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ginsenoside Rf

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CAS Number: 52286-58-5Picture of molecule3D/inchi
FDA UNII: JOS8BON5YW
MDL:MFCD00210509
XlogP3-AA:2.70 (est)
Molecular Weight:801.02464000
Formula:C42 H72 O14
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 921.00 °C. @ 760.00 mm Hg (est)
Flash Point: 951.00 °F. TCC ( 510.80 °C. ) (est)
logP (o/w): 3.560 (est)
Soluble in:
 water, 0.1125 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Ginsenoside Rf 98%
BOC Sciences
For experimental / research use only.
Ginsenoside Rf
ExtraSynthese
For experimental / research use only.
Ginsenoside Rf (HPLC) ≥98%
Santa Cruz Biotechnology
For experimental / research use only.
Ginsenoside Rf
Sigma-Aldrich
For experimental / research use only.
Ginsenoside Rf
analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 1340 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 539, 1975.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for ginsenoside Rf usage levels up to:
 not for fragrance use.
 
Recommendation for ginsenoside Rf flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6441008
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
Chemidplus:0052286585
RTECS:LY9536900 for cas# 52286-58-5
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):6441008
Pubchem (sid):135117839
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C08945
HMDB (The Human Metabolome Database):HMDB34745
FooDB:FDB013289
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 ginseng
Search Trop Picture
 
Synonyms:
 ginsenoside RF
 panaxoside Rf
 panaxoside RF
 

Articles:

PubMed:Discrimination of white ginseng origins using multivariate statistical analysis of data sets.
PubMed:Detoxifying effect of fermented black ginseng on H2O2-induced oxidative stress in HepG2 cells.
PubMed:[Determination of twelve active compounds in Qili Qiangxin capsules by UPLC-MS].
PubMed:Metabolomic approach for discrimination of processed ginseng genus (Panax ginseng and Panax quinquefolius) using UPLC-QTOF MS.
PubMed:Efficacy comparison of Korean ginseng and American ginseng on body temperature and metabolic parameters.
PubMed:[Chemical constituents from roots and rhizomes of Panax ginseng cultivated in Jilin province].
PubMed:Induction of G2/M phase cell cycle arrest and apoptosis by ginsenoside Rf in human osteosarcoma MG‑63 cells through the mitochondrial pathway.
PubMed:Production of aglycone protopanaxatriol from ginseng root extract using Dictyoglomus turgidum β-glycosidase that specifically hydrolyzes the xylose at the C-6 position and the glucose in protopanaxatriol-type ginsenosides.
PubMed:Updating chemical profiling of red ginseng via the elucidation of two geometric isomers of ginsenosides Rg9 and Rg10.
PubMed:Ginsenjilinol, a new protopanaxatriol-type saponin with inhibitory activity on LPS-activated NO production in macrophage RAW 264.7 cells from the roots and rhizomes of Panax ginseng.
PubMed:Effects of ginsenoside on pacemaker potentials of cultured interstitial cells of Cajal clusters from the small intestine of mice.
PubMed:Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways.
PubMed:Mass spectrometric imaging of ginsenosides localization in Panax ginseng root.
PubMed:Rapid qualitative and quantitative analyses of Asian ginseng in adulterated American ginseng preparations by UPLC/Q-TOF-MS.
PubMed:Microbial conversion of rare ginsenoside Rf to 20(S)-protopanaxatriol by Aspergillus niger.
PubMed:On-line concentration of neutral analytes by complexation and acetonitrile sweeping in nonionic microemulsion electrokinetic chromatography with direct ultraviolet detection.
PubMed:Biotransformation of ginsenoside Rf to Rh1 by recombinant beta-glucosidase.
PubMed:Direct on-line analysis of neutral analytes by dual sweeping via complexation and organic solvent field enhancement in nonionic MEKC.
PubMed:[A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].
PubMed:Pressure and electrokinetic injections for on-line sample stacking neutral analytes in microemulsion electrokinetic chromatography with salt-containing matrixes.
PubMed:Ultra-performance LC/TOF MS analysis of medicinal Panax herbs for metabolomic research.
PubMed:Neuroprotective effects of ginseng saponins against L-type Ca2+ channel-mediated cell death in rat cortical neurons.
PubMed:Retention behavior of ginsenosides on a poly(vinyl alcohol)-bonded stationary phase in hydrophilic interaction chromatography.
PubMed:Inhibitory effects of Korean red ginseng and its genuine constituents ginsenosides Rg3, Rf, and Rh2 in mouse passive cutaneous anaphylaxis reaction and contact dermatitis models.
PubMed:Ginsenoside Rf, a component of ginseng, regulates lipoprotein metabolism through peroxisome proliferator-activated receptor alpha.
PubMed:Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytes.
PubMed:[Study on the chemical constituents of the roots of commercial ginseng].
PubMed:Phytochemistry of wild populations of Panax quinquefolius L. (North American ginseng).
PubMed:Effects of ginsenosides on glycine receptor alpha1 channels expressed in Xenopus oocytes.
PubMed:[Practical optimization of the two-dimensional thin-layer chromatographic separation of ginsenosides].
PubMed:Ginsenoside Rf potentiates U-50,488H-induced analgesia and inhibits tolerance to its analgesia in mice.
PubMed:Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus laevis oocytes.
PubMed:The antimetastatic and immunomodulating activities of ginseng minor glycosides.
PubMed:Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions.
PubMed:Use of high-performance liquid chromatography-tandem mass spectrometry to distinguish Panax ginseng C. A. Meyer (Asian ginseng) and Panax quinquefolius L. (North American ginseng).
PubMed:Preparation of monoclonal antibody against ginsenoside Rf and its enzyme immunoassay.
PubMed:Differentiation and authentication of Panax ginseng, Panax quinquefolius, and ginseng products by using HPLC/MS.
PubMed:Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity.
PubMed:Ginsenoside Rf2, a new dammarane glycoside from Korean red ginseng (Panax ginseng).
PubMed:Determination of ginsenoside Rf and Rg2 from Panax ginseng using enzyme immunoassay.
PubMed:Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice.
PubMed:A trace component of ginseng that inhibits Ca2+ channels through a pertussis toxin-sensitive G protein.
PubMed:Saponins from Vietnamese Ginseng, Panax vietnamensis HA et Grushv. Collected in central Vietnam. II.
PubMed:[Suppression of lipid peroxidation by sho-saiko-to and its components in rat liver subcellular membranes].
PubMed:[Isolation and identification of saponin IV, V, VI and VII in ginseng stems].
 
Notes:
from ginseng. Constit. of Panax ginseng (ginseng). The first pure ginseng constit. to show nearly all the activities of the plant extract
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