EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

harmalol hydrochloride
3H-pyrido(3,4-b)indol-7-ol, 4,9-dihydro-1-methyl-, monohydrochloride

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Name:1-methyl-2,3,4,9-tetrahydropyrido[3,4-b]indol-7-one;hydrochloride
CAS Number: 6028-07-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:227-898-9
FDA UNII: Search
Molecular Weight:236.70081000
Formula:C12 H13 Cl N2 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Harmalol hydrochloride >95%
Odor: characteristic
Use: Harmalol hydrochloride is found in the herbs of Peganum harmala L.
ExtraSynthese
For experimental / research use only.
Harmalol Hydrochloride (HPLC) ≥90%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-mouse LD50 100 mg/kg
U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03207

intraperitoneal-mouse LDLo 230 mg/kg
Quarterly Journal of Pharmacy & Pharmacology. Vol. 3, Pg. 218, 1930.

Dermal Toxicity:
subcutaneous-frog LDLo 250 mg/kg
BEHAVIORAL: REGIDITY LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Quarterly Journal of Pharmacy & Pharmacology. Vol. 3, Pg. 218, 1930.

subcutaneous-guinea pig LDLo 300 mg/kg
Quarterly Journal of Pharmacy & Pharmacology. Vol. 3, Pg. 218, 1930.

subcutaneous-mouse LDLo 380 mg/kg
Quarterly Journal of Pharmacy & Pharmacology. Vol. 3, Pg. 218, 1930.

subcutaneous-rabbit LDLo 300 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: MUSCLE WEAKNESS CARDIAC: PULSE RATE
Quarterly Journal of Pharmacy & Pharmacology. Vol. 3, Pg. 218, 1930.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for harmalol hydrochloride usage levels up to:
 not for fragrance use.
 
Recommendation for harmalol hydrochloride flavor usage levels up to:
 not for flavor use.
 
Safety References:
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5459187
National Institute of Allergy and Infectious Diseases:Data
1-methyl-2,3,4,9-tetrahydropyrido[3,4-b]indol-7-one;hydrochloride
Chemidplus:0006028075
 
References:
 1-methyl-2,3,4,9-tetrahydropyrido[3,4-b]indol-7-one;hydrochloride
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5459187
Pubchem (sid):135103860
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
4,9-dihydro-1-methyl-3H-pyrido(3,4-b)indol-7-ol hydrochloride
 harmalol HCl
1-methyl-2,3,4,9-tetrahydropyrido[3,4-b]indol-7-one;hydrochloride
3H-pyrido(3,4-b)indol-7-ol, 4,9-dihydro-1-methyl-, monohydrochloride
 
 
Notes:
None found
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