EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

hederagenin
olean-12-en-28-oic acid, 3,23-dihydroxy-, (3-beta,4-alpha)-

Supplier Sponsors

Name:(4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carbo
CAS Number: 465-99-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:207-369-9
FDA UNII: RQF57J8212
Nikkaji Web:J1.536I
XlogP3-AA:6.80 (est)
Molecular Weight:472.70936000
Formula:C30 H48 O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 589.40 °C. @ 760.00 mm Hg (est)
Flash Point: 616.00 °F. TCC ( 324.30 °C. ) (est)
logP (o/w): 7.410 (est)
Soluble in:
 water, 0.003427 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Hederagenin 98%
BOC Sciences
For experimental / research use only.
Hederagenin >97%
Carbosynth
For experimental / research use only.
Hederagenin
ExtraSynthese
For experimental / research use only.
Hederagenin (HPLC) ≥98.5%
Santa Cruz Biotechnology
For experimental / research use only.
Hederagenin
Sigma-Aldrich: Sigma
For experimental / research use only.
Hederagenin ≥97% (HPLC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 600 mg/kg
Indian Journal of Medical Research. Vol. 58, Pg. 724, 1970.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for hederagenin usage levels up to:
 not for fragrance use.
 
Recommendation for hederagenin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :73299
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carbo
Chemidplus:0000465996
 
References:
 (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carbo
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):73299
Pubchem (sid):135030311
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 astrantiagenin E
 caulosapogenin
(3-beta,4-alpha)-3,23-dihydroxyolean-12-en-28-oic acid
 olean-12-en-28-oic acid, 3-beta,23-dihydroxy- (6CI,7CI,8CI)
 olean-12-en-28-oic acid, 3,23-dihydroxy-, (3-beta,4-alpha)-
 olean-12-en-28-oic acid, 3,23-dihydroxy-, (3beta,4alpha)- (9CI)
 olean-12-en-28-oic acid, 3beta,23-dihydroxy- (8CI)
 

Articles:

PubMed:Triterpenoid Glycosides from Medicago sativa as Antifungal Agents against Pyricularia oryzae.
PubMed:Hederagenin from the leaves of ivy (Hedera helix L.) induces apoptosis in human LoVo colon cells through the mitochondrial pathway.
PubMed:Synthesis of Cyclocaric Acid A and Comparison to Material from Cyclocarya paliurus.
PubMed:Simultaneous quantification of Akebia saponin D and its five metabolites in human intestinal bacteria using ultra-performance liquid chromatography triple quadrupole mass spectrometry.
PubMed:A strategy for characterization of triterpene saponins in Caulophyllum robustum hairy roots by liquid chromatography with electrospray ionization quadrupole time-of-flight mass spectrometry.
PubMed:Inhibition of COX-2 and PGE2 in LPS-stimulated RAW264.7 cells by lonimacranthoide VI, a chlorogenic acid ester saponin.
PubMed:Antinociceptive activity of the HPLC- and MS-standardized hydroethanolic extract of Pterodon emarginatus Vogel leaves.
PubMed:Metabolites profiling of Pulsatilla saponin D in rat by ultra performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF-MS/MS).
PubMed:A new triterpenoid saponin and an oligosaccharide isolated from the fruits of Sapindus mukorossi.
PubMed:Determination of asperosaponin VI and its active metabolite hederagenin in rat tissues by LC-MS/MS: application to a tissue distribution study.
PubMed:Domain formation and permeabilization induced by the saponin α-hederin and its aglycone hederagenin in a cholesterol-containing bilayer.
PubMed:Oleanane-type glycosides from Tremastelma palaestinum (L.) Janchen.
PubMed:Pharmacokinetics study of asperosaponin VI and its metabolites cauloside A, HN saponin F and hederagenin.
PubMed:A new oleanane-type triterpenoidal saponin from Pulsatilla chinensis.
PubMed:[Study on pharmacokinetics of asperosaponin VI and its active metabolite in rats].
PubMed:[Chemical constituents of Dipsacus asper].
PubMed:Bioactive oleanane-type saponins from the rhizomes of Anemone taipaiensis.
PubMed:[Quality survey of different species of clematidis radix et rhizoma].
PubMed:New cytotoxic triterpenoid saponins from the whole plant of Clematis lasiandra Maxim.
PubMed:Anti-HIV-1 integrase compound from Pometia pinnata leaves.
PubMed:Chemical constituents of Swertia yunnanensis and their anti-hepatitis B virus activity.
PubMed:Triterpene glucosides from the leaves of Aralia elata and their cytotoxic activities.
PubMed:Induction of highly curved structures in relation to membrane permeabilization and budding by the triterpenoid saponins, α- and δ-Hederin.
PubMed:Combinatorial biosynthesis of legume natural and rare triterpenoids in engineered yeast.
PubMed:A new feruloyl tyramine glycoside from the roots of Achyranthes bidentata.
PubMed:A new monodesmosidic triterpenoid saponin from the leaves of Pometia pinnata.
PubMed:Studies on cytotoxic triterpene saponins from the leaves of Aralia elata.
PubMed:Triterpene saponin content in the roots of red beet (Beta vulgaris L.) cultivars.
PubMed:Plant metabolomics: resolution and quantification of elusive peaks in liquid chromatography-mass spectrometry profiles of complex plant extracts using multi-way decomposition methods.
PubMed:Chemical constituents of Arisaema franchetianum tubers.
PubMed:UDP-glycosyltransferases from the UGT73C subfamily in Barbarea vulgaris catalyze sapogenin 3-O-glucosylation in saponin-mediated insect resistance.
PubMed:Chemical investigation of saponins from twelve annual Medicago species and their bioassay with the brine shrimp Artemia salina.
PubMed:[Alpha-glucosidase inhibitory active constituents contained in nutshell of Trapa acornis].
PubMed:Triterpene acids from Euscaphis japonica and assessment of their cytotoxic and anti-NO activities.
PubMed:Three new triterpenoid saponins from root of Gardenia jasminoides Ellis.
PubMed:Antimicrobially active hederagenin glycosides from Cephalaria elmaliensis.
PubMed:Triterpenes from Callicarpa integerrima Champ.
PubMed:Cytotoxic triterpene saponins from the leaves of Aralia elata.
PubMed:Two new cytotoxic triterpenoid saponins from the roots of Clematis argentilucida.
PubMed:Triterpene saponins from the roots of Dipsacus asper and their protective effects against the Aβ(25-35) induced cytotoxicity in PC12 cells.
PubMed:Triterpenoid saponins from the root of Anemone tomentosa.
PubMed:[Mass spectrometry of triterpene glycosides molecular complexation with purine bases of nucleic acids].
PubMed:The extracts of Fructus Akebiae, a preparation containing 90% of the active ingredient hederagenin: serotonin, norepinephrine and dopamine reuptake inhibitor.
PubMed:Effect of triterpenes and triterpene saponins from the stem bark of Kalopanax pictus on the transactivational activities of three PPAR subtypes.
PubMed:Two new triterpenoid glycosides from the leaves of Anthocephalus chinensis.
PubMed:Simultaneous determination of asperosaponin VI and its active metabolite hederagenin in rat plasma by liquid chromatography-tandem mass spectrometry with positive/negative ion-switching electrospray ionization and its application in pharmacokinetic study.
PubMed:Anti-inflammatory triterpenoid saponins from the stem bark of Kalopanax pictus.
PubMed:Triterpenoid saponins from Dipsacus asper and their activities in vitro.
PubMed:Constituents of the root of Anemone tomentosa.
PubMed:[Triterpenoid saponins of Alternanthera philoxeroides (Mart.) Griseb].
PubMed:Quantitative determination of hederagenin in rat plasma and cerebrospinal fluid by ultra fast liquid chromatography-tandem mass spectrometry method.
PubMed:Fatty acid synthase inhibitors from the hulls of Nephelium lappaceum L.
PubMed:Triterpenoid glycosides from the leaves of two cultivars of Medicago polymorpha L.
PubMed:Effects of the dichloromethane fraction of Dipsaci Radix on the osteoblastic differentiation of human alveolar bone marrow-derived mesenchymal stem cells.
PubMed:Structural elucidations and spectral assigments of two novel triterpene glycosides from Cephalaria paphlagonica.
PubMed:Antimicrobial and antioxidant effects of phenolic constituents from Klainedoxa gabonensis.
PubMed:Variation in saponin content during the growing season of spotted medic [Medicago arabica (L.) Huds.].
PubMed:Pre-treatment with α-hederin increases β-adrenoceptor mediated relaxation of airway smooth muscle.
PubMed:Structure-biological activity relationships in triterpenic saponins: the relative activity of protobassic acid and its derivatives against plant pathogenic fungi.
PubMed:The hederagenin saponin SMG-1 is a natural FMLP receptor inhibitor that suppresses human neutrophil activation.
PubMed:Triterpene saponins from Clematis chinensis and their potential anti-inflammatory activity.
PubMed:New resistance-correlated saponins from the insect-resistant crucifer Barbarea vulgaris.
PubMed:Genomic and coexpression analyses predict multiple genes involved in triterpene saponin biosynthesis in Medicago truncatula.
PubMed:Resistance in the plant, Barbarea vulgaris, and counter-adaptations in flea beetles mediated by saponins.
PubMed:Isolation and structure determination of acetylated triterpenoid saponins from the seeds of Centratherum anthelminticum.
PubMed:[Advance in chemical constituents of genus Clematis].
PubMed:[Chemical constituents of roots of Boehmeria nivea].
PubMed:[Constituents from Alternanthera philoxeroides and their antitumor activity].
PubMed:Inhibitory effects of diterpene acids from root of Aralia cordata on IgE-mediated asthma in guinea pigs.
PubMed:Screening for feeding deterrent and insect growth regulatory activity of triterpenic saponins from Diploknema butyracea and Sapindus mukorossi.
PubMed:Antidepressant effect of the extracts from Fructus Akebiae.
PubMed:A new triterpene hexaglycoside from the bark of Kalopanax septemlobus (Thunb.) Koidz.
PubMed:Rapid analysis of constituents of Radix Cyathulae using hydrophilic interaction-reverse phase LC-MS.
PubMed:Identification of defense compounds in Barbarea vulgaris against the herbivore Phyllotreta nemorum by an ecometabolomic approach.
PubMed:[Chemical constituents from roots of Phlomis umbrosa].
PubMed:Akebia saponin D, a saponin component from Dipsacus asper Wall, protects PC 12 cells against amyloid-beta induced cytotoxicity.
PubMed:Triterpenoid saponins from the stems of Clematis parviloba.
PubMed:Bidesmoside triterpenoid glycosides from Stauntonia chinensis and relationship to anti-inflammation.
PubMed:Macranthoside B, a hederagenin saponin extracted from Lonicera macranthoides and its anti-tumor activities in vitro and in vivo.
PubMed:Preparative isolation and purification of isobenzofuranone derivatives and saponins from seeds of Nigella glandulifera Freyn by high-speed counter-current chromatography combined with gel filtration.
PubMed:Alpha-hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors.
PubMed:New triterpenic saponins from the aerial parts of Medicago arabica (L.) huds.
PubMed:Structures of acetylated oleanane-type triterpene saponins, rarasaponins IV, V, and VI, and anti-hyperlipidemic constituents from the pericarps of Sapindus rarak.
PubMed:Molluscicidal saponins from leaves of Hedera canariensis.
PubMed:Enhanced triterpene saponin biosynthesis and root nodulation in transgenic barrel medic (Medicago truncatula Gaertn.) expressing a novel beta-amyrin synthase (AsOXA1) gene.
PubMed:A new naturally acetylated triterpene saponin from Nigella sativa.
PubMed:Effect of hydrolysis on the yield of hederagenin and High-performance thin-layer chromatography densitometric quantification of hederagenin in fruit pericarp of Sapindus spp.
PubMed:Active component of Fatsia japonica enhances the transduction efficiency of Tat-SOD fusion protein both in vitro and in vivo.
PubMed:[Chemical constituents in root of Hemerocallis fulva].
PubMed:A convenient preparation of a disaccharide motif and its role in the cytotoxicity of the triterpenoid saponin, alpha-hederin.
PubMed:Triterpene saponins from Chenopodium quinoa Willd.
PubMed:[Triterpenoid saponins from flower bud of Jasminum officinale var. grandiflorum].
PubMed:Triterpenoid saponins from the fruits and galls of Sapindus mukorossi.
PubMed:Antifungal activity of the extracts and saponins from Sapindus saponaria L.
PubMed:[Triterpene glycosides from the aerial parts of Pulsatilla chinensis].
PubMed:[Comparative study on quality of Flos Lonicerae between geo-authentic and non-authentic producing areas].
PubMed:Pancreatic lipase-inhibiting triterpenoid saponins from fruits of Acanthopanax senticosus.
PubMed:A new lupene triterpenetriol and anticholinesterase activity of Salvia sclareoides.
PubMed:Triterpenoid saponins from Stauntonia chinensis.
PubMed:Remote hydroxylation of methyl groups by regioselective cyclopalladation. Partial synthesis of hyptatic acid-A.
PubMed:Triterpene saponin hemi-biosynthesis of a leaf beetle's (Platyphora kollari) defensive secretion.
PubMed:Four new triterpene glycosides from Nigella damascena.
PubMed:Antioxidant constituents and a new triterpenoid glycoside from Flos Lonicerae.
PubMed:Cytotoxic triterpenoid saponins from the roots of Cephalaria gigantea.
PubMed:Effect of five triterpenoid compounds from the buds of Aralia elata on stimulus-induced superoxide generation, tyrosyl phosphorylation and translocation of cytosolic compounds to the cell membrane in human neutrophils.
PubMed:Antidermatophyte activity of medicago extracts and contained saponins and their structure-activity relationships.
PubMed:Bioactive flavonoids and saponins from Climacoptera obtusifolia.
PubMed:Triterpenoid saponins from the stem bark of Caryocar villosum.
PubMed:Structure-activity relationships of some hederagenin diglycosides: haemolysis, cytotoxicity and apoptosis induction.
PubMed:Antimicrobial activity of saponins from Medicago sp.: structure-activity relationship.
PubMed:Triterpene saponins from the roots of Medicago hybrida.
PubMed:[Study on sterols and triterpenes from the stems of Akebia quinata].
PubMed:Triterpenoid saponins from the fruits of Caryocar glabrum.
PubMed:The antioxidant activity of a triterpenoid glycoside isolated from the berries of Hedera colchica: 3-O-(beta-D-glucopyranosyl)-hederagenin.
PubMed:Antitumor activity of Pulsatilla koreana saponins and their structure-activity relationship.
PubMed:Cytotoxic saponins from the root of Dipsacus asper Wall.
PubMed:[Chemical constituents from rhizome of Pulsatilla dahurica].
PubMed:[Studies on chemical constituents in the seeds of Nigella glandulifera].
PubMed:Complete 1H and 13C NMR assignments of six saponins from Sapindus trifoliatus.
PubMed:Two new saponins from Zygophyllum atriplicoides.
PubMed:Bioactive constituents of the leaves of Phyllanthus polyphyllus var. siamensis.
PubMed:Saponins and other constituents from the leaves of Aralia elata.
PubMed:Quality evaluation of Flos lonicerae through a simultaneous determination of seven saponins by HPLC with ELSD.
PubMed:Antinociceptive and anti-inflammatory effects of the saponin and sapogenins obtained from the stem of Akebia quinata.
PubMed:Genomics-based selection and functional characterization of triterpene glycosyltransferases from the model legume Medicago truncatula.
PubMed:Triterpenoid saponins from the roots of Pulsatilla koreana.
PubMed:Structure elucidation by NMR spectroscopy of a new acetylated saponin from Centratherum anthelminticum.
PubMed:Triterpenoid saponins from leaves of Hedera pastuchowii.
PubMed:Structures of four new triterpenoid saponins from the leaves of Oplopanax elatus Nakai.
PubMed:Synthesis and hemolytic activity of some hederagenin diglycosides.
PubMed:Anti-platelet pentacyclic triterpenoids from leaves of Campsis grandiflora.
PubMed:Structure-activity relationship of oleanane disaccharides isolated from Akebia quinata versus cytotoxicity against cancer cells and NO inhibition.
PubMed:Further saponins from Meryta lanceolata.
PubMed:Triterpene saponins from aerial parts of Medicago arabica L.
PubMed:Recycling plant wax constituents for chemical defense: hemi-biosynthesis of triterpene saponins from beta-amyrin in a leaf beetle.
PubMed:Molluscicidal saponins from Sapindus mukorossi, inhibitory agents of golden apple snails, Pomacea canaliculata.
PubMed:Two new antifungal saponins from the Tibetan herbal medicine Clematis tangutica.
PubMed:Eranthisaponins A and B, two new bisdesmosidic triterpene saponins from the tubers of Eranthis cilicica.
PubMed:An unusual case of death: suffocation caused by leaves of common ivy (Hedera helix). Detection of hederacoside C, alpha-hederin, and hederagenin by LC-EI/MS-MS.
PubMed:Bioactive crude plant seed extracts from the NCAUR oilseed repository.
PubMed:[Studies on chemical constituents of Galeopsis bifida].
PubMed:Antitrichomonas in vitro activity of Cussonia holstii Engl.
PubMed:Loniceroside C, an antiinflammatory saponin from Lonicera japonica.
PubMed:[Isolation and identification of triterpenoide compound from Patrinia scabiosaefolia].
PubMed:[Analysis of surface-active substances in Sapindus mukurossi by high performance liquid chromatography-mass spectrometry].
PubMed:A genomics approach to the early stages of triterpene saponin biosynthesis in Medicago truncatula.
PubMed:In vitro activity of hederacolchisid A1 compared with other saponins from Hedera colchica against proliferation of human carcinoma and melanoma cells.
PubMed:[Studies on the chemical constituents of Patrinia scabiasaefolia fisch].
PubMed:Oleanane saponins in "kancolla", a sweet variety of Chenopodium quinoa.
PubMed:The active constituents from Gualou-xiebai-baijiu-tang part I: active saponins.
PubMed:[Triterpenes and steroidal compounds from Momordica dioica].
PubMed:Triterpenoid saponins from Oreopanax guatemalensis.
PubMed:In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells.
PubMed:Identification of a triterpenoid saponin from a crucifer, Barbarea vulgaris, as a feeding deterrent to the diamondback moth, Plutella xylostella.
PubMed:Triterpene saponins from debittered quinoa (Chenopodium quinoa) seeds.
PubMed:Metabolism of kalopanaxsaponin K by human intestinal bacteria and antirheumatoid arthritis activity of their metabolites.
PubMed:Antinociceptive and anti-rheumatoidal effects of Kalopanax pictus extract and its saponin components in experimental animals.
PubMed:Anti-lipid peroxidative principles from the stem bark of Kalopanax pictus Nakai.
PubMed:Kalopanaxsaponin A from Kalopanax pictus, a potent antioxidant in the rheumatoidal rat treated with Freund's complete adjuvant reagent.
PubMed:Characterization of the triterpene saponins of the roots and rhizomes of blue cohosh (Caulophyllum thalictroides).
PubMed:Acetylated triterpene saponins from the Thai medicinal plant, Sapindus emarginatus.
PubMed:New oleanane saponins in Chenopodium quinoa.
PubMed:Two unusual oleanane saponins from Anemone anhuiensis.
PubMed:Antifungal activity of modified hederagenin glycosides from the leaves of Kalopanax pictum var. chinense.
PubMed:Studies on the constituents of Clematis species. VIII. Triterpenoid saponins from the aerial part of Clematis tibetana KUNTZ.
PubMed:[Triterpene saponins from Pulsatilla cernua].
PubMed:Identification and biological activities of triterpenoid saponins from Chenopodium quinoa.
PubMed:Kalopanaxsaponin A is a basic saponin structure for the anti-tumor activity of hederagenin monodesmosides.
PubMed:Five saponins from the root bark of Aralia elata.
PubMed:[New triterpenoid saponins from Anemone begoniifolia].
PubMed:Triterpenoid saponins from Fagonia cretica.
PubMed:Triterpenoidal saponins from Cornulaca monacantha.
PubMed:Essential moiety for antimutagenic and cytotoxic activity of hederagenin monodesmosides and bisdesmosides isolated from the stem bark of Kalopanax pictus.
PubMed:Triterpene saponins from the fruits of Hedera helix.
PubMed:Triterpenoid saponins from Bongardia chrysogonum.
PubMed:Triterpene saponins and lignans from the roots of Pulsatilla chinensis and their cytotoxic activity against HL-60 cells.
PubMed:Two oleanene glycosides from the aerial parts of Caltha polypetala.
PubMed:In vitro anticomplementary activity of hederagenin saponins isolated from roots of Dipsacus asper.
PubMed:Inhibition of mouse ear edema by steroidal and triterpenoid saponins.
PubMed:Five new triterpene saponins from Pulsatilla patens var. multifida.
PubMed:Studies on the constituents of Clematis species. VII. Triterpenoid saponins from the roots of Clematis terniflora DC. var. robusta Tamura.
PubMed:Two new sulfated saponins from the roots of Gypsophila bermejoi.
PubMed:Saponins from Gliricidia sepium.
PubMed:Medicinal foodstuffs. XII. Saponin constituents with adjuvant activity from hyacinth bean, the seeds of Dolichos lablab L. (1): Structures of lablabosides A, B, and C.
PubMed:Metabolism of kalopanaxsaponin B and H by human intestinal bacteria and antidiabetic activity of their metabolites.
PubMed:A triterpenoid saponin from Patrinia scabiosaefolia.
PubMed:In vitro antispasmodic compounds of the dry extract obtained from Hedera helix.
PubMed:Hederagenin glycosides from the flowers of Cephalaria transsylvanica.
PubMed:Leonticins D-H, five triterpene saponins from Leontice kiangnanensis.
PubMed:Triterpenoid saponins from Anemone hupehensis.
PubMed:Two new saponins, congmuyenosides A and B, from the leaves of Aralia elata collected in Heilongjiang, China.
PubMed:Leonticins A-C, three octasaccharide saponins from Leontice kiangnanensis.
PubMed:Triterpenoid glycosides from bark of Meliosma lanceolata.
PubMed:Antifungal and molluscicidal saponins from Serjania salzmanniana.
PubMed:Triterpenoid saponins from Cephalaria transsylvanica.
PubMed:[Studies on the chemical constituents of seed from Nigella glandulifera].
PubMed:Chemistry and biological activity of triterpenoid glycosides from Medicago sativa.
PubMed:Triterpenoidal saponins from Dumasia truncata.
PubMed:Studies on the constituents of Clematis species. VI. The constituents of Clematis stans Sieb. et Zucc.
PubMed:Antitumor agents, 162. Cell-based assays for identifying novel DNA topoisomerase inhibitors: studies on the constituents of Fatsia japonica.
PubMed:Medicinal foodstuffs. I. Hypoglycemic constituents from a garnish foodstuff "taranome," the young shoot of Aralia elata SEEM.: elatosides G, H, I, J, and K.
PubMed:Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency.
PubMed:Hederagenin glycosides from Pometia eximia.
PubMed:A bidesmosidic hederagenin hexasaccharide from the roots of Symphytum officinale.
PubMed:Patensin, a saponin from Pulsatilla patens var. multifida.
PubMed:[Triterpene glycosides from Hedera taurica. XIII. Structure of taurosides St-I1 and St-I2 from Crimean ivy stems].
PubMed:Triterpenoid saponins from Clematis chinensis.
PubMed:Structure elucidation of an acetylated saponin of Blighia welwitschii by NMR spectroscopy.
PubMed:Synergistic spermicidal activity of neem seed extract, reetha saponins and quinine hydrochloride.
PubMed:A bidesmosidic triterpene glycoside from the roots of Symphytum officinale.
PubMed:Triterpenoid saponins from the aerial parts of Lonicera japonica.
PubMed:In vitro antifungal activity of triterpenoid saponins.
PubMed:Triterpenoid saponins from Dianthus chinensis.
PubMed:The effects of 10 triterpenoid compounds on experimental liver injury in mice.
PubMed:Triterpene glycosides from thalictri herba. II.
PubMed:Triterpene glycosides from the roots of Dipsacus asper.
PubMed:Triterpenoid saponins from Anemone hupehensis.
PubMed:Triterpenoid glycosides from Stauntonia hexaphylla.
PubMed:Saponins from leaves of Acanthopanax sieboldianus.
PubMed:A New Bidesmosidic Triterpenoidal Saponin from the Roots of Symphytum officinale.
PubMed:Comparison of cytoprotective effects of saponins isolated from leaves of Aralia elata Seem. (Araliaceae) with synthesized bisdesmosides of oleanoic acid and hederagenin on carbon tetrachloride-induced hepatic injury.
PubMed:Triterpenoid glycosides from Stauntonia hexaphylla.
PubMed:Two triterpenoidal saponins from sapindus, mukorossi gaertn.
PubMed:Allelopathic potentials of alfalfa (Medicago sativa) saponins: Their relation to antifungal and hemolytic activities.
PubMed:Clemontanoside-C, a saponin from Clematis montana.
PubMed:Symphytoxide A, a triterpenoid saponin from the roots of Symphytum officinale.
PubMed:[Structure determination of saponin XI, XII and XIII from Dipsacus asper Wall].
PubMed:Adjuvanticity and ISCOM formation by structurally diverse saponins.
PubMed:[Structure determination of saponin IX and X from Dipsacus asper Wall].
PubMed:Inhibition of human leucocyte elastase by ursolic acid. Evidence for a binding site for pentacyclic triterpenes.
PubMed:Saponins of the ivy plant, Hedera helix, and their leishmanicidic activity.
PubMed:Saponins from the stem bark of Kalopanax pictum var. magnificum (I).
PubMed:[New triterpenoid glycosides from Dipsacus asper Wall].
PubMed:[Studies on the chemical constituents of Dipsacus asper Wall].
PubMed:Saponins from leaves of Acanthopanax hypoleucus Makino.
PubMed:Clematoside-S, a triterpenoid saponin from the roots of Clematis grata.
PubMed:Saponins from leaves of Kalopanax pictum var. maximowiczii, a Korean medicinal plant.
PubMed:[Studies on the chemical constituents of Lonicera fulvotomentosa Hsu et S.C. Cheng].
PubMed:Inhibition of the tumor-promoting action of 12-O-tetradecanoylphorbol-13-acetate by some oleanane-type triterpenoid compounds.
PubMed:[Anti-inflammatory effects of fulvotomentosasides].
PubMed:Triterpenoid Saponins from Caltha palustris.
PubMed:[Use of a strain of Aspergillus niger for purification of a hederagenin rhamnoglucoside from tubers of ficaria(Ficaria ranunculoides Moench)].
PubMed:The structure-hemolysis relationship of oleanolic acid derivatives and inhibition of the saponin-induced hemolysis with sapogenins.
PubMed:Anti-inflammatory activities of hederagenin and crude saponin isolated from Sapindus mukorossi Gaertn.
PubMed:Chemical structure and antifungal activity of a number of triterpenoids.
PubMed:Isolation of a saponin, hederin, and its sapogenin, hederagenin, from bur clover (Medicago hispida).
 
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