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homatropine
DL-mandelsaeure-tropylester

Supplier Sponsors

Name:[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2-phenylacetate
CAS Number: 87-00-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:201-716-8
FDA UNII: 8QS6WCL55Z
Nikkaji Web:J253.896B
Beilstein Number:0087959
XlogP3:1.90 (est)
Molecular Weight:275.34797000
Formula:C16 H21 N O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed:Search
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 99.50 °C. @ 760.00 mm Hg
Boiling Point: 403.30 °C. @ 760.00 mm Hg (est)
Flash Point: 388.00 °F. TCC ( 197.70 °C. ) (est)
logP (o/w): 1.570 (est)
Soluble in:
 water, 1.00E+04 mg/L @ 15 °C (exp)
 water, 1.07e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
homatropine 98%
ExtraSynthese
For experimental / research use only.
Homatropine (HPLC) ≥90%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 370 mg/kg
French Demande Patent Document. Vol. #2035763

oral-mouse LD50 1307 mg/kg
French Demande Patent Document. Vol. #2035763

intraperitoneal-rat LDLo 180 mg/kg
Toxicology and Applied Pharmacology. Vol. 1, Pg. 156, 1959.

Dermal Toxicity:
subcutaneous-mouse LD50 1800 mg/kg
French Demande Patent Document. Vol. #2035763

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for homatropine usage levels up to:
 not for fragrance use.
 
Recommendation for homatropine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5282593
National Institute of Allergy and Infectious Diseases:Data
[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2-phenylacetate
Chemidplus:0000087003
 
References:
 [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2-phenylacetate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5282593
Pubchem (sid):134971426
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C07814
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 homatropin
 homoatropine
 homotropine
 mandelic acid, 3d-tropanyl ester
DL-mandelsaeure-tropylester
 mandelyltropeine
 mandelytropeine
[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2-phenylacetate
 methylhomatropinum
 omatropina
(RS)-3alpha(1alphaH,5alphaH)-tropanylmandelat
 tropine, mandelate (ester)
 tropinmandelsaeureester
3alpha-tropylmandelat
 

Articles:

PubMed:The effect of topical adrenergic and anticholinergic agents on the choroidal thickness of young healthy adults.
PubMed:Simultaneous determination of atropine, scopolamine, and anisodamine from Hyoscyamus niger L. in rat plasma by high-performance liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetics study.
PubMed:Role of the autonomic nervous system and baroreflex in stress-evoked cardiovascular responses in rats.
PubMed:Adenosine deaminase activity modulation by some street drug: molecular docking simulation and experimental investigation.
PubMed:Myomatous hepatic angiomyolipoma: imaging findings in 14 cases with radiological-pathological correlation and review of the literature.
PubMed:Development and validation of a LC-MS/MS method for homocysteine thiolactone in plasma and evaluation of its stability in plasma samples.
PubMed:Effects of different mydriatics on intraocular pressure, pupil diameter, and ruminal and intestinal motility in healthy sheep.
PubMed:Effect of Homatropine eye drops on pain after photorefractive keratectomy: A pilot study.
PubMed:Acute onset myopia as a presenting feature of systemic lupus erythematosus.
PubMed:Combined use of ionic liquid and hydroxypropyl-β-cyclodextrin for the enantioseparation of ten drugs by capillary electrophoresis.
PubMed:Is surgery necessary for patients with hepatic angiomyolipoma? Retrospective analysis from eight Chinese cases.
PubMed:NMDA receptors in the lateral hypothalamus have an inhibitory influence on the tachycardiac response to acute restraint stress in rats.
PubMed:[Systemic adverse effects of topical ocular instillation of atropine in two children].
PubMed:A misleading hepatic tumour: epithelioid angiomyolipoma.
PubMed:Stromal rejection after big bubble deep anterior lamellar keratoplasty: case series and review of literature.
PubMed:Combined use of ionic liquid and β-CD for enantioseparation of 12 pharmaceuticals using CE.
PubMed:Acute anterior uveitis following zoledronic acid infusion for osteoporosis.
PubMed:Simulation of the effects of complex-formation equilibria in electrophoresis: III. Simultaneous effects of chiral selector concentration and background electrolyte pH.
PubMed:Efficacy assessment of various anticholinergic agents against topical sarin-induced miosis and visual impairment in rats.
PubMed:Effect of tropicamide and homatropine eye drops on a-scan parameters of the phakic normal eyes.
PubMed:Hepatic angiomyolipoma with a giant hemangioma.
PubMed:Efficacy of tropicamide, homatropine, cyclopentolate, atropine and hyoscine as mydriatics in Angora goats.
PubMed:A pallid paroxysmal event in children: it is vagal anoxic seizure, it is treatable, and it is not "epilepsy".
PubMed:Development of a liquid chromatography-tandem mass spectrometric method for the simultaneous determination of tropane alkaloids and glycoalkaloids in crops.
PubMed:Bilateral microbial keratitis in highly active antiretroviral therapy-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: a case series.
PubMed:An old drug for use in the prevention of sudden infant unexpected death due to vagal hypertonia.
PubMed:Comparing homatropine and atropine in pediatric cycloplegic refractions.
PubMed:[Comparison of topic mydriasis and mydriasis achieved by soaked cellulose in the conjunctival sac].
PubMed:Topical chloramphenicol prophylaxis is of dubious benefit in corneal abrasion.
PubMed:The role of the cholinergic system of the bed nucleus of the stria terminalis on the cardiovascular responses and the baroreflex modulation in rats.
PubMed:Development and validation of a highly sensitive LC-MS/MS method for organic cation transporter (OCT) substrate tetraethylammonium (TEA) in rabbits.
PubMed:Unusual presentation of phacolytic glaucoma: simulating microbial keratitis.
PubMed:Is homatropine 5% effective in reducing pain associated with corneal abrasion when compared with placebo? A randomized controlled trial.
PubMed:Diagnostic and prognostic role of galectin 3 expression in cutaneous melanoma.
PubMed:Hepatic angiomyolipoma: a case report.
PubMed:Syphilitic palmoplantar keratoderma and ocular disease: a rare combination in an HIV-positive patient.
PubMed:Inhibitory effect of anticholinergics on the contraction of isolated caprine urinary bladder detrusor muscle.
PubMed:The endogenous cannabinoid, anandamide, inhibits dopamine transporter function by a receptor-independent mechanism.
PubMed:LC-ESI MS/MS quantification of atropine and six other antimuscarinic tropane alkaloids in plasma.
PubMed:A hepatic lipoma mimicking angiomyolipoma of the liver: report of a case.
PubMed:Vasopressin and sympathetic systems mediate the cardiovascular effects of the GABAergic system in the bed nucleus of the stria terminalis.
PubMed:Two differing presentations of chronic bilateral anterior uveitis.
PubMed:Bed nucleus of the stria terminalis N-methyl-D-aspartate receptors and nitric oxide modulate the baroreflex cardiac component in unanesthetized rats.
PubMed:Flow-injection turbidimetric determination of homatropine methylbromide in pharmaceutical formulations using silicotungstic acid as precipitant reagent.
PubMed:Bed nucleus of the stria terminalis alpha(1)-adrenoceptor modulates baroreflex cardiac component in unanesthetized rats.
PubMed:Role of the bed nucleus of the stria terminalis in the cardiovascular responses to acute restraint stress in rats.
PubMed:Hepatic angiomyolipoma.
PubMed:Hypotony maculopathy in a patient with HLA-B27-associated uveitis.
PubMed:Capillary electrophoresis of tropane alkaloids and glycoalkaloids occurring in Solanaceae plants.
PubMed:Granuloma annulare anterior uveitis.
PubMed:Cardiovascular effects of L-glutamate injected in the medial prefrontal cortex of spontaneously hypertensive rats.
PubMed:Intramuscular ophthalmic homatropine vs. atropine to prevent lethality in rates with dichlorvos poisoning.
PubMed:Peripheral ulcerative keratitis with bilateral optic nerve involvement as an initial presentation of acute lymphocytic leukemia in an adult.
PubMed:Acute retinal necrosis complicating chickenpox in a healthy adult--a case report and review of literature.
PubMed:Enantioseparation of chiral tropa alkaloids by means of cyclodextrin-modified microemulsion electrokinetic chromatography.
PubMed:True moving bed electrophoresis using stepped electric field gradients.
PubMed:Pretreating rats with parenteral ophthalmic antimuscarinic agents decreases mortality from lethal organophosphate poisoning.
PubMed:[Neurotoxic effects induced by the topical administration of cycloplegics. A case report and review of the literature].
PubMed:Increasing the scale of true moving bed electrophoretic separations using filtration to reduce solvent volumetric flows between sections II and III.
PubMed:Hepatic angiomyolipoma with trace amounts of fat: a case report and literature review.
PubMed:Role of the medial prefrontal cortex in cardiovascular responses to acute restraint in rats.
PubMed:Homatropine and psychosis in Weill-Marchesani syndrome.
PubMed:Evaluation of amniotic membrane transplantation as an adjunct to medical therapy as compared with medical therapy alone in acute ocular burns.
PubMed:Pressor and tachycardic responses evoked by microinjections of L-glutamate into the medial prefrontal cortex of unanaesthetized rats.
PubMed:Dense membrane formation after combined phacoemulsification-trabeculectomy surgery.
PubMed:Frontotemporal dementia with co-occurrence of astrocytic plaques and tufted astrocytes, and severe degeneration of the cerebral white matter: a variant of corticobasal degeneration?
PubMed:Acute posterior multifocal placoid pigment epitheliopathy after meningococcal C conjugate vaccine.
PubMed:Identification and estimation of the levo isomer in raw materials and finished products containing atropine and/or hyoscyamine.
PubMed:Familial HLA-A2- and HLA-B7-associated anterior uveitis.
PubMed:Multifocal choroiditis--an unusual finding in Crohn's disease.
PubMed:Human carboxylesterase 1: from drug metabolism to drug discovery.
PubMed:Microbial keratitis and vision loss with contact lenses.
PubMed:Tubulointerstitial nephritis and uveitis syndrome.
PubMed:Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme.
PubMed:Scavenging of photogenerated oxidative species by antimuscarinic drugs: atropine and derivatives.
PubMed:Characterizing the subjective, psychomotor, and physiological effects of a hydrocodone combination product (Hycodan) in non-drug-abusing volunteers.
PubMed:Bilateral panuveitis in a child with hypohidrotic ectodermal dysplasia.
PubMed:Topical ketorolac tromethamine 0.5% versus diclofenac sodium 0.1% to inhibit miosis during cataract surgery.
PubMed:[Effect of pilocarpine and cycloplegic substances on ophthalmic tone in healthy eyes and ones with glaucoma].
PubMed:[An ultrasound biomicroscopic study on changes of the structure of ocular anterior segment after topical application of cycloplegia].
PubMed:Mechanisms involved in the water intake-related pressor response in the rat.
PubMed:Herpes simplex virus type 1 associated acute retinal necrosis following encephalitis.
PubMed:Contact allergy to atropine and other mydriatic agents in eye drops.
PubMed:Ultrasound biomicroscopic study on changes of ocular anterior segment structure after topical application of cycloplegia.
PubMed:[Neurological manifestations in the intoxication of infants by dimethicone combined with homatropine: report of 6 cases].
PubMed:Tris(2,2'-bipyridine)ruthenium(II) electrogenerated chemiluminescence of alkaloid type drugs with solid phase extraction sample preparation.
PubMed:Muscarinic mediation of the urethro genital reflex in spinal cord-transected rats.
PubMed:Masculine copulatory behavior is facilitated by intrathecally administered muscarine.
PubMed:Effect of the dry-cold season dormancy on the tonic and phasic neural control of heart rate in the toad, Bufo paracnemis.
PubMed:Crack eye syndrome.
PubMed:Enantioseparation of tropa alkaloids by means of anionic cyclodextrin-modified capillary electrophoresis.
PubMed:Chiral resolution of atropine, homatropine and eight synthetic tropinyl and piperidinyl esters by capillary zone electrophoresis with cyclodextrin additives.
PubMed:[Epidemiology of drug use during the first three months of life in a urban area of southern Brazil].
PubMed:Infectious keratopathy complicating photorefractive keratectomy.
PubMed:Bilateral hyphemas and cataracts after diode laser retinal photoablation for retinopathy of prematurity.
PubMed:Occupational allergic contact dermatitis from homatropine and phenylephrine eyedrops.
PubMed:Development and validation of a capillary zone electrophoresis method for the determination of atropine, homatropine and scopolamine in ophthalmic solutions.
PubMed:Systemic toxicity from ocular homatropine.
PubMed:Topical analgesia for superficial corneal injuries.
PubMed:Significance of mobile phase composition in enantioseparation of chiral drugs by HPLC on a cellulose-based chiral stationary phase.
PubMed:Pupillary and cardiovascular responses to the cold-pressor test.
PubMed:Cataract extraction and Parkinson's disease.
PubMed:Inadvertent instillation of Minims eye drops.
PubMed:Anterior segment ischemia after the Jensen procedure in a 10-year-old patient.
PubMed:Buspirone, but not sumatriptan, induces miosis in humans: relevance for a serotoninergic pupil control.
PubMed:Inadvertent instillation of Minims eye drops in an ophthalmic casualty department.
PubMed:Interference of mandelic acid with the determination of homatropine hydrobromide by second-order derivative spectroscopy.
PubMed:Use of topical nonsteroidal anti-inflammatory drugs in excimer laser photorefractive keratectomy.
PubMed:[Partition behavior of tropane alkaloids between organic solvents and water].
PubMed:Muscarinic receptors in the aortae of normo- and hypertensive rats: a binding study.
PubMed:The trigemino-pupillary reflex: a model of sensory-vegetative integration.
PubMed:Preoperative topical flurbiprofen-Na+ in extracapsular lens extraction role in maintaining intraoperative pupillary dilatation.
PubMed:The effect of topical corticosteroids on refractive outcome and corneal haze after photorefractive keratectomy. A prospective, randomized, double-blind trial.
PubMed:Anticholinergic delirium caused by topical homatropine ophthalmologic solution: confirmation by anticholinergic radioreceptor assay in two cases.
PubMed:Ultrasonic study to see the effect of topical pilocarpine and homatropine on anterior chamber depth in phakic cases.
PubMed:The effect of tarsorrhaphy on normal healing of corneal epithelial defects in a rabbit model.
PubMed:Analysis of tropane alkaloids with thermospray high-performance liquid chromatography-mass spectrometry.
PubMed:Determination of homatropine hydrobromide in eye drops by second-order derivative spectroscopy.
PubMed:In vivo pupillary constrictor effects of substance P in man.
PubMed:Transcutaneous electrical stimulation applied to the infratrochlear nerve induces a homatropine-resistant miosis in humans.
PubMed:[Correction of the symptoms of late substance withdrawal syndrome by intra-conjunctival administration of 5% homatropine solution (preliminary report)].
PubMed:[Drug therapy of progressive myopia].
PubMed:Positive diagnosis of self-medication with homatropine eye drops.
PubMed:Acanthamoeba keratitis successfully treated with prolonged propamidine isethionate and neomycin-polymyxin-gramicidin.
PubMed:Atropine- and scopolamine-resistant subtypes of muscarinic receptors in the rabbit aorta.
PubMed:[Prokinetic drugs in gastrointestinal motility. Their application in pediatrics].
PubMed:Tachycardia precipitated by topical homatropine.
PubMed:Characterization of the discriminative stimulus effects of physostigmine in the rat.
PubMed:Ocular manifestations of syphilis.
PubMed:Possible non-muscarinic miotic action of echothiophate iodide in humans.
PubMed:Pupil responsiveness in diabetes mellitus.
PubMed:Characterization of the antimuscarinic effect of heptane-1,7-bis-(dimethyl-3'-phthalimidopropyl ammonium bromide).
PubMed:Acute closed-angle glaucoma after arteriovenous fistulas.
PubMed:Status of cyclopentolate as a cycloplegic in children: a comparison with atropine and homatropine.
PubMed:Production and characterization of high-affinity monoclonal antibodies against morphine.
PubMed:Homatropine-associated confusion in an elderly patient.
PubMed:An evaluation of the effectiveness of intramuscular atropine or homatropine eyedrops in preventing the effects of physostigmine eyedrops on human vision.
PubMed:Effects of mydriatic agents on neutrophil migration.
PubMed:PVC membrane electrodes of anisodamine, N-butylscopolamine and homatropine.
PubMed:Separation of optical isomers of scopolamine, cocaine, homatropine, and atropine.
PubMed:Interaction of himbacine with carbachol at muscarinic receptors of heart and smooth muscle.
PubMed:Application of second-derivate UV spectrophotometry to the determination of homatropine methylbromide in single-component dosage form.
PubMed:[Endocrinological and neurophysiological modifications in a case of atropinic delusional state].
PubMed:Homatropine eyedrops change sleep and mood disorders in depressive patients.
PubMed:A comparison of cycloplegic and manifest refractions on the NR-1000F (an objective Auto Refractometer).
PubMed:A quantitative investigation into the effects of pupil diameter and defocus on contrast sensitivity for an extended range of spatial frequencies in natural and homatropinized eyes.
PubMed:Repeated delirium from homatropine eye-drops. A case report.
PubMed:Reduction in plasma prolactin levels in depressed women after homatropine administration.
PubMed:Comparative behavioral effects of anticholinergic agents in cats: psychomotor stimulation and aggression.
PubMed:The cardio-selectivity of himbacine: a muscarine receptor antagonist.
PubMed:Failure of gallamine and pancuronium to inhibit selectively (-)-[3H]quinuclidinyl benzilate binding in guinea-pig atria.
PubMed:Treatment of snake venom ophthalmia.
PubMed:Morphine eye-drops reduce homatropine induced mydriasis in man.
PubMed:[Gas chromatography determination of atropine, theophylline, phenobarbital and aminophenazone in tablets].
PubMed:Cogan's syndrome: a treatable cause of neurosensory deafness.
PubMed:Influence of antimuscarinics on alpha-adrenoceptors in the female rabbit urethra.
PubMed:Effect of urea on the activity of certain ophthalmic drugs in man.
PubMed:Angiotensin-converting enzyme in sarcoid perivasculitis.
PubMed:Structure-activity requirements for hypotension and alpha-adrenergic receptor blockade by analogues of atropine.
PubMed:4-(Diphenylmethyl)-1-[(imino)methyl]piperidines as gastric antisecretory agents.
PubMed:Effect of one year clofazimine therapy on autonomic functions in lepromatous leprosy with lepra (ENL) reaction.
PubMed:Latent dysautonomic pupillary lateralization in cluster headache. A pupillometric study.
PubMed:Memo on medications: atropine sulfate and homatropine hydrobromide: common mydriatic/cycloplegic agents.
PubMed:Ocular toxoplasmosis treatment and clinical monitoring of the patient.
PubMed:Evaluation of laser iridectomy in angle-closure glaucoma: provocative tests.
PubMed:Modification by hexamethonium of the muscarinic receptors blocking activity of pancuronium and homatropine in isolated tissues of the guinea-pig.
PubMed:Cardiovascular reflexes in conscious toads.
PubMed:A study of autonomic functions in leprosy.
PubMed:Mydriatic and cycloplegic drugs: a review of ocular and systemic complications.
PubMed:Application of one-phase end-point change system in two-phase titration to amine drug analysis.
PubMed:Effect of antimuscarinic agents on the contractile responses to cholinomimetics in the rat anococcygeus muscle.
PubMed:[Limits of pharmacodynamic differentiation of pupillary-disturbances (author's transl)].
PubMed:The selective antimuscarinic action of stercuronium.
PubMed:Radioimmunoassay for atropine and l-hyoscyamine.
PubMed:The failure of conventional drug therapy in the management of infantile colic.
PubMed:Poisoning with homatropine.
PubMed:[Cycloplegia with cyclopentolate for testing-refraction of children (author's transl)].
PubMed:Relapsing polychondritis in a Latin American man.
PubMed:Effect of variations in temperature on antimuscarinic activity in guinea-pig atria.
PubMed:Rectal absorption of homatropine [14C]methylbromide in the rat.
PubMed:Atropine substitutes and the writhing syndrome in mice.
PubMed:Measurements of the air conditioning capacity of the nose during normal and pathological conditions and pharmacological influence.
PubMed:A second conponent of atropine mydriasis.
PubMed:[Photometric determination of homatropine hydrobromide in eyedrops].
PubMed:Analysis of homatropine methylbromide dosage forms.
PubMed:Effect of atropine on vascular adrenergic neuroeffector transmission.
PubMed:[Effect of phenactil (chlorpromazine) on cortical visual evoked potentials in clinically healthy subjects with normal and abnormal electroencephalograms].
PubMed:Anticholinergic activities of D(-)R- and L(+)S-mandeloylcholines.
PubMed:Analysis of alkaloid mixtures by charge-transfer complexation.
PubMed:Influence of thymoxamine on changes in pupil diameter and accommodation produced by homatropine and ephedrine.
PubMed:Analysis of Duboisia myoporoides R. Br. and Duboisia leichhardtii F. Muell.
PubMed:Antimuscarinic action of an alkane-bis-ammonium compound alone and in combination with (+)-benzetimide.
PubMed:[Cycloplegia and residual accommodation (author's transl)].
PubMed:[Pupil's reaction to atropine, homatropine, neosynephrine and adrenaline in experimental hyperlipemia and human atherosclerosis].
PubMed:Role of the blood-brain barrier in the anticholinergic differential effects on LH and prolactin release in proestrous rats.
PubMed:Specific analysis for homatropine methylbromide in syrups.
PubMed:[Analysis of the molecule complexes of atropine and homatropine with mercury-(II)-chloride].
PubMed:A nonfatal case of intentional scopolamine poisoning.
PubMed:The effects of conjunctival instillation of eserine and homatropine on pupillary reactivity in schizophrenics.
PubMed:Nonsolvolytic acetylation of homatropine by aspirin.
PubMed:GLC analysis of homatropine methylbromide in tablets and elixirs.
PubMed:[Reaction of atropine and homatropine with mercury(II)-chloride].
PubMed:[Homatropine extraction from aqueous solutions with organic solvents as dependent on the pH of the medium].
PubMed:Stability-indicating method for analysis of homatropine methylbromide in pharmaceutical formulations.
PubMed:The action of physostigmine, morphine, cyclopentolate and homatropine on the secretion and outflow of aqueous humour in the rabbit eye.
PubMed:Provocative test combining water drinking and homatropine eye drops. Applanation versus tonography.
PubMed:Relationships between ocular dimensions and the effects of provocative tests. Water drinking. Homatropine eye drops. Water drinking and homatropine eye drops.
PubMed:Effect of temperature on solubilization and hydrolytic degradation of solubilized benzocaine and homatropine.
PubMed:Colorimetric determination of atropine, homatropine, scopolamine, and their derivatives by the ferric hydroxamate method.
PubMed:Homatropine bradycardia in man.
PubMed:Stabilization of homatropine methylbromide-iodobismuthate complex in solution for quantitative analysis of homatropine methylbromide.
PubMed:Provocative outflow test. Combining water drinking and homatropine.
PubMed:[The identification of atropine, homatropine, acopolamine and pilocarpine as impurities in eye drops].
PubMed:[Homatropine hydrobromide].
PubMed:[Applications of gas chromatography in pharmaceutical analysis. IX. Separation and determination of atropine and homatropine and their control in pharmaceutical preparations].
PubMed:Stability determination of homatropine hydrobromide by direct cerimetric titration.
PubMed:Stability of homatropine in aqueous solution.
PubMed:Adrenolytic activity of atropine, (+)-hyoscyamine, atroscine, homatropine, and related compounds.
PubMed:[A case of acute psychosis following use of a 1 per cent homatropine solution].
PubMed:EVALUATION OF ANISOCORIA AFTER THE USE OF HOMATROPINE IN NEUROSURGICAL PATIENTS.
PubMed:SOME EFFECTS OF ATROPINE ON SMOOTH MUSCLE.
PubMed:HOMATROPINE HYDROBROMIDE. EFFECT OF TOPICAL ADMINISTRATION UPON THE INTRAOCULAR PRESSURE AND AQUEOUS FACILITY VALUES OF NORMAL AND CHRONIC SIMPLE GLAUCOMATOUS EYES.
PubMed:[Use of a 4 per cent solution of homatropine hydrobromide for the determination of refraction in young patients].
PubMed:The studies on the residual accomodation of Koreans. I. The residual accomodation under 1 percent atropine and 5 percent homatropine cycloplegia.
PubMed:CLINICAL EVALUATION OF A NEW MYDRIATIC-MYDRILATE.
PubMed:[On the effect of atropine and homatropine on accomodation in determination of refraction].
PubMed:Influence of morphine, codeine, meperidine, ephedrine and homatropine methylbromide upon absorption of aspirin from the gastro-intestinal tract of man.
PubMed:Toxic effects of atropine and homatropine eyedrops in children.
PubMed:[Symptomatic treatment of Meniere's syndrome with homatropine methylbromide].
PubMed:[Observations on the use in neurosurgery of a new hypotensive drug: phenacyl homatropine chloride].
PubMed:Prolonged treatment of peptic ulcer with homatropine methylbromide: a study of 58 patients under continuous therapy for periods up to one year.
PubMed:The kinetics of the hydrolysis of homatropine methylbromide and atropine methylbromide.
PubMed:[Additional data on the pharmacodynamics of phenacyl homatropine chloride, a short-acting ganglion-blocking agent].
PubMed:The kinetics of the hydrolysis of homatropine.
PubMed:[Poisoning caused by ingestion of homatropine eyewash].
PubMed:[Acute psychopathological accident in a 13 year old boy after conjunctival administration of homatropine].
PubMed:Effect of certain drugs on the iris vessels; the action of isoflurophate and homatropine on the rat's eye.
PubMed:[Acute psychopathological accident in a 13 year old boy after conjunctival administration of homatropine].
PubMed:The effect of homatropine on the accomodation-convergence association.
PubMed:Ophthalmic vehicles: the effect of methylcellulose on the penetration of homatropine hydrobromide through the cornea.
PubMed:Adjunctive anticholinergic treatment with homatropine methylbromide; a preliminary report.
PubMed:The effect of homatropine methyl bromide on human gastrointestinal motor activity.
PubMed:[Effect of homatropine on tension of normal and glaucomatous eye].
PubMed:[Suspected scopolamine poisoning in instillation with homatropine eye drops].
PubMed:[Homatropine and ocular hypertension].
PubMed:Residual accommodation: a method for its objective determination: with an analysis of several different cycloplegics, especially homatropine (five percent) in methylcellulose and zephiran.
PubMed:The use of several new drugs as substitutes for homatropine.
PubMed:Residual accommodation under homatropine-cocaine cycloplegia.
PubMed:[Visual acuity following administration of homatropine into eyes with various states of refraction but with normal vision].
PubMed:Homatropine methylbromide; a pharmacological reevaluation.
PubMed:A note on the determination of purity of homatropine methyl bromide.
PubMed:Chronic biliary disease in general practice.
PubMed:The colorimetric determination of homatropine methylbromide.
PubMed:The action of atropine, homatropine, eserine and prostigmine on the osmotic pressure of the aqueous humour.
PubMed:Effects of atropine sulfate, methylatropine nitrate (metropine) and homatropine hydrobromide on adult human eyes.
PubMed:THE OCCURRENCE AND DISTRIBUTION OF ATROPINESTERASE, AND THE SPECIFICITY OF TROPINESTERASES.
PubMed:Transient Pulsation of Retinal Arteries induced by Application of Homatropine.
PubMed:The inefficiency of Hydrobromate of Homatropine in controlling Accommodation.
PubMed:Mydriasis of one Eye, with intact accommodation lasting four months after application of Homatropine to both eyes.
 
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