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lanatoside B

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CAS Number: 17575-21-2Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:241-545-6
FDA UNII: 3822U6I4Z0
Nikkaji Web:J53.670I
Beilstein Number:0078394
MDL:MFCD00016800
XlogP3:0.50 (est)
Molecular Weight:985.12872000
Formula:C49 H76 O20
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -0.250 (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Lanatoside B
ExtraSynthese
For experimental / research use only.
Lanatoside B (HPLC) ≥85%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-cat LD50 388 ug/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 31, Pg. 236, 1942.

intravenous-guinea pig LDLo 3695 ug/kg
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 252, Pg. 314, 1966.

intravenous-rat LDLo 12 ug/kg
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 177, Pg. 60, 1934.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for lanatoside B usage levels up to:
 not for fragrance use.
 
Recommendation for lanatoside B flavor usage levels up to:
 not for flavor use.
 
Safety References:
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :72604
National Institute of Allergy and Infectious Diseases:Data
Chemidplus:0017575212
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):72604
Pubchem (sid):135152000
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 digilanid B
 digilanide B
 lanatosid B
 

Articles:

PubMed:High-performance liquid chromatography-ionspray mass spectrometry for the specific determination of digoxin and some related cardiac glycosides in human plasma.
PubMed:Subalpinoside (S1), an Unknown Oleandrigenin Glycoside and Other Cardenol from Digitalis subalpina var. subalpina.
PubMed:Toxicokinetic-toxicodynamic models describing the relation of plasma and red blood cell potassium with plasma digitalis in acute human digitalis poisoning.
PubMed:Human cell mutants affected in the interaction of the 12 beta-OH group of cardiac glycosides with the digitalis receptor.
PubMed:[The contraction of intestinal myocells and block of cationic pumps].
PubMed:[Electrocardiographic changes in the rat induced by high doses of the coenzymatic forms of several vitamins of the B group].
PubMed:Bio-Transformation of (G-3H)-digitoxin and (G-3H)-digoxin by Digitalis purpurea.
PubMed:Effects of age and growth regulators on serially propagated Digitalis Ianata leaf and root cultures.
PubMed:Species restriction of the mitogenicity induced by lanatoside C. Lymphocyte activation by digitalis glycosides is confined to cells from digitalis resistant species.
PubMed:Lanatoside C, a new polyclonal B-cell activator.
PubMed:Molecular basis of B cell activation: mitogenicity of native and modified digitalis glycosides.
PubMed:Functional characterization of lanatoside-C-responsive cells.
PubMed:Rapid and sensitive high-resolution procedure for digitalis glycoside analysis by derivatization liquid chromatography.
PubMed:[HEART THERAPY WITH LANATOSIDE C, THEOPHYLLINE AND VITAMIN B FACTORS].
PubMed:[Comparison of lanatoside A, B, C, D on the heart-lung preparation in cats].
 
Notes:
None found
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