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lanatoside C
desacetyllanatoside

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Name:[6-[6-[6-[[12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-hydroxy-2
CAS Number: 17575-22-3Picture of molecule3D/inchi
Other(deleted CASRN):11019-78-6
ECHA EINECS - REACH Pre-Reg:241-546-1
FDA UNII: 5RR3JFZ771
MDL:MFCD00869432
XlogP3:0.20 (est)
Molecular Weight:985.12872000
Formula:C49 H76 O20
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): 0.070
Soluble in:
 water, 0.3613 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Lanatoside C (Digoxin Impurity H)
Carbosynth
For experimental / research use only.
Lanatoside C
ExtraSynthese
For experimental / research use only.
Lanatoside C (HPLC) ≥95%
Santa Cruz Biotechnology
For experimental / research use only.
Lanatoside C ≥97%
Sigma-Aldrich: Sigma
For experimental / research use only.
Lanatoside C ≥95%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-cat LDLo 230 ug/kg
Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 657, 1969.

intravenous-dog LD50 340 ug/kg
CARDIAC: OTHER CHANGES
Indian Veterinary Journal. Vol. 57, Pg. 31, 1980.

intravenous-frog LD50 790 ug/kg
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 61, Pg. 231, 1965.

oral-guinea pig LD50 100 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 481, 1965.

intravenous-guinea pig LDLo 502 ug/kg
Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 1237, 1967.

intraperitoneal-mouse LD50 7 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 165, 1965.

intravenous-mouse LD50 8100 ug/kg
Drugs in Japan Vol. 6, Pg. 877, 1982.

intravenous-rat LD50 16500 ug/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 848, 1961.

intraperitoneal-rat LDLo 10 mg/kg
Toxicology and Applied Pharmacology. Vol. 1, Pg. 156, 1959.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for lanatoside C usage levels up to:
 not for fragrance use.
 
Recommendation for lanatoside C flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :3879
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
[6-[6-[6-[[12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-hydroxy-2
Chemidplus:0017575223
 
References:
 [6-[6-[6-[[12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-hydroxy-2
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):3879
Pubchem (sid):135042462
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 digitalis lanata leaf
Search Trop Picture
 
Synonyms:
 cedilanid
 ceglunate
 celadigal
 celanid
 celanidum
 cetosanol
 desacetyllanatoside
 digilanid C
 digilanide C
 isolanid
 lanatosid C
 lanatosidum C
isolanide
 lanimerck
 lanocide-C
 

Articles:

PubMed:Antiviral activity of lanatoside C against dengue virus infection.
PubMed:Identification of natural compound inhibitors for multidrug efflux pumps of Escherichia coli and Pseudomonas aeruginosa using in silico high-throughput virtual screening and in vitro validation.
PubMed:Hydrogen peroxide-induced antioxidant activities and cardiotonic glycoside accumulation in callus cultures of endemic Digitalis species.
PubMed:Systemic anticancer neural stem cells in combination with a cardiac glycoside for glioblastoma therapy.
PubMed:Protein-protein interaction network analysis in chronic obstructive pulmonary disease.
PubMed:Calcium and magnesium elimination enhances accumulation of cardenolides in callus cultures of endemic Digitalis species of Turkey.
PubMed:Regioselective diversification of a cardiac glycoside, lanatoside C, by organocatalysis.
PubMed:Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor-related apoptosis-inducing ligand and induces an alternative cell death pathway.
PubMed:Digitalis-like induced arrhythmia in a patient with rheumatic mitral regurgitation complicated by preeclampsia.
PubMed:Optimization and validation of a high-performance liquid chromatography method for the analysis of cardiac glycosides in Digitalis lanata.
PubMed:Some solutions to obtain very efficient separations in isocratic and gradient modes using small particles size and ultra-high pressure.
PubMed:Drug therapy of paroxysmal atrial fibrillation in the elderly over 75 years old.
PubMed:[Cardiac glycosides in complex treatment of patients with heart failure and supraventricular arrhythmias].
PubMed:Systemic induction of the biosynthesis of terpenic compounds in Digitalis lanata.
PubMed:Cytotoxicity of digitoxin and related cardiac glycosides in human tumor cells.
PubMed:[Lanatoside C Reference Standard (Control 981) of National Institute of Health Sciences].
PubMed:Induction of digoxin-like material production, and the digoxin binding in the unicellular organism Tetrahymena by digitoxin.
PubMed:High-performance liquid chromatography-ionspray mass spectrometry for the specific determination of digoxin and some related cardiac glycosides in human plasma.
PubMed:Isolation of cardenolides from a Brazilian cultivar of Digitalis lanata by rotation locular counter-current chromatography.
PubMed:Enzymatic transformation of de-O-acetyl-lanatoside C into digoxin.
PubMed:[When, why, and how to treat atrial fibrillation].
PubMed:The effects of the purinergic system on digitalis-induced epileptiform activity.
PubMed:Digitalis restores the forearm sympathetic response to cardiopulmonary receptor unloading in hypertensive patients with left ventricular hypertrophy.
PubMed:[Determination of cardenolides in Digitalis lanata by a solid-phase immunoenzyme method].
PubMed:[Comparative study of the effect of cycloartane and cardiac glycosides on various parameters of myocardial metabolism in animals].
PubMed:[A study on the hemodynamic effect of cedilanid in the treatment of acute myocardial infarction].
PubMed:Adenosine. An evaluation of its use in cardiac diagnostic procedures, and in the treatment of paroxysmal supraventricular tachycardia.
PubMed:Prolonged duration of myocardial ischemia in patients with coronary heart disease and impaired cardiopulmonary baroreceptor sensitivity.
PubMed:Mechanics of vomiting: a minireview.
PubMed:Toxicokinetic-toxicodynamic models describing the relation of plasma and red blood cell potassium with plasma digitalis in acute human digitalis poisoning.
PubMed:Effects of crotoxin on the isolated guinea pig heart.
PubMed:Production and characterization of monoclonal and polyclonal antibodies against digoxin.
PubMed:Contribution of clinical pharmacology to a rational use of cardiac glycosides in Czechoslovakia.
PubMed:[Utilization of cardiac glycosides in Czechoslovakia--does it correspond to need?].
PubMed:Clinical utility of plasma digoxin measurements.
PubMed:[Use of digitalis 1981 to 1988 in the Frankfurt (Oder) district].
PubMed:Comparative effects of captopril, nitroprusside, dopamine and lanatoside C on a new model of rabbit congestive heart failure.
PubMed:Human cell mutants affected in the interaction of the 12 beta-OH group of cardiac glycosides with the digitalis receptor.
PubMed:Electrophysiological study on hypertrophied and ischemic myocardial of rats.
PubMed:Electrophysiological mechanisms for the initiation and maintenance of ventricular fibrillation in nonischemic rabbit hearts.
PubMed:[Treatment of patients with acute digitalis poisoning by charcoal hemoperfusion].
PubMed:[Practical use of computer technics and nomograms in controlling treatment using digitalis preparations].
PubMed:[Guidelines for prescription of the assay of digitalis glycosides by immunologic methods].
PubMed:Effects of digitalis on cardiopulmonary baroreflex in man.
PubMed:Isolation and quantitative determination of some cardioactive glycosides from Digitalis lanata by high-performance liquid chromatography.
PubMed:[Clinical application of the determination of serum digoxin concentration].
PubMed:[Determination of isolanid in cadaveric material].
PubMed:Digitalis-induced augmentation of cardiopulmonary baroreflex control of forearm vascular resistance.
PubMed:Effect of chlordiazepoxide on experimentally induced centrogenic arrhythmias in anaesthetized dogs.
PubMed:[Treatment of arrhythmia in pregnancy].
PubMed:Selective impairment of baroreflex-mediated vasoconstrictor responses in patients with ventricular dysfunction.
PubMed:Digitalis glycosides: mechanisms and manifestations of toxicity. Part I.
PubMed:[Arrest of rhythmic disorders in an outpatient polyclinic].
PubMed:Protective effect of nifedipine upon digitalis intoxication.
PubMed:[Curbing of arrhythmias under outpatient polyclinic conditions].
PubMed:[Effect of a single dose of lanatoside C on the left heart ventricle in patients with primary congestive cardiomyopathy].
PubMed:[The contraction of intestinal myocells and block of cationic pumps].
PubMed:Modification of the baroreceptor control of atrio-ventricular conduction induced by digitalis in man.
PubMed:[Electrocardiographic changes in the rat induced by high doses of the coenzymatic forms of several vitamins of the B group].
PubMed:[Electrocardiographic changes in the rat induced by digitalis glucosides].
PubMed:[Studies on the usefulness of calcium-potassium and sodium-potassium indicators for the detection of the toxic effect of cardiac glycosides].
PubMed:[Effect of strophanthin and celanide on the autoregulation of the cerebral blood flow].
PubMed:The digital circulation in congestive heart failure.
PubMed:Cortical control of neurally-mediated arrhythmogenic properties of desacetyl lanatoside C: the role of the posterior hypothalamus.
PubMed:Bio-Transformation of (G-3H)-digitoxin and (G-3H)-digoxin by Digitalis purpurea.
PubMed:[Effect of strophanthin and celanide on brain blood supply and metabolism].
PubMed:Treatment of paroxysmal supraventricular tachycardia in infancy with digitalis, adenosine-5'-triphosphate, and verapamil: a comparative study.
PubMed:[Digitalis drugs].
PubMed:Effect of sheng mai san on left ventricular performance in coronary heart disease.
PubMed:[Effect of the cardiac glycosides lanatoside C and strophanthin K on left on left ventricular function in patients with mitral stenosis].
PubMed:[Effect of strophanthin and celanide on the tonus of the cerebral and peripheral vessels].
PubMed:Transformation of 12-deoxycardenolids with Streptomyces purpurascens.
PubMed:[Effect of digoxin, strophanthin and isolanid on oxygen absorption, oxidative phosphorylation and the amount of cytochromes in the myocardial mitochondria and their ATPase activity].
PubMed:[Prevention of frequent paroxysmal ventricular tachycardia by combined use of anti-arrhythmia drugs].
PubMed:Synthesis and biological activity of digitoxigenin aminoesters.
PubMed:Therapeutic effects and pharmacokinetics of beta-methyldigoxin.
PubMed:Clinical implications of serum digoxin concentrations.
PubMed:[Comparative evaluation of the effect of digoxin, strophanthin, isolanid and corglycon on the indices of central hemodynamics, vascular tonus, circulating blood volume and myocardial contractility in acute heart failure].
PubMed:Digitalis and baroreceptor reflexes in man.
PubMed:Effect of lanatoside C on right ventricular function and pulmonary circulation in patients with mitral stenosis.
PubMed:[Toxic effects and pharmacokinetics of cardiac glycosides in mice with experimental radiation disease].
PubMed:[Relationship between blood serum magnesium and potassium levels in patients with right-ventricular circulatory insufficiency treated with lanatoside C, and the role of magnesium in the prevention of digitalis-induced arrhythmias].
PubMed:Cedilanid (lanatoside C)
PubMed:Changeover from lanatoside C to digoxin.
PubMed:[Effects of Coronilla varia Linné extract and lanatoside C in rabbits with experimental acute heart overloading in vivo].
PubMed:A study of the pharmacology of lanatoside C in experimentally induced pathophysiological conditions.
PubMed:[Changes in adenosine triphosphatase activity in the heart after administration of lanatoside C in irradiated and non-irradiated rabbits with acute cardiac overload].
PubMed:[The toxic effects and pharmacokinetics of lanatoside C in animals with experimental radiation sickness or trimepranol premedication].
PubMed:Some effects of lanatoside C in irradiated rabbits with acute heart overloading.
PubMed:Treatment of a case of lanatoside C intoxication with digoxin-specific F(ab')2 antibody fragments.
PubMed:[Nifedipine effect upon experimental digitalis toxicity (author's transl)].
PubMed:[Lanatoside C concentration in the blood serum of patients treated with this drug].
PubMed:[Comparative study of blood serum concentrations of digoxin and lanatoside C after single oral administration].
PubMed:Species restriction of the mitogenicity induced by lanatoside C. Lymphocyte activation by digitalis glycosides is confined to cells from digitalis resistant species.
PubMed:[Effects of inotropic drugs on the indices of systolic time intervals and diastolic time intervals (author's transl)].
PubMed:[The National Institute of Hygienic Sciences Reference Standard (the Japanese Ppharmacopoeia Standard) "Lanatoside C Reference Standard" (author's transl)].
PubMed:[Creatine phosphokinase release from perfused cardiac muscle under hypoxic conditions. Effect of propranolol, verapamil, reserpine and deslanoside].
PubMed:[Use of digitalis glycosides in severe disorders of intra-ventricular conduction].
PubMed:Lanatoside C, a new polyclonal B-cell activator.
PubMed:Molecular basis of B cell activation: mitogenicity of native and modified digitalis glycosides.
PubMed:[Intestinal absorption and metabolism of lanatoside C].
PubMed:Functional characterization of lanatoside-C-responsive cells.
PubMed:Absorption and metabolism of lanatoside C. II. Fate after oral administration.
PubMed:[Clinical study of the biological availability of lanatoside C and digoxin in long-term tests].
PubMed:[Variability in the lanatoside C content of harvested leaves and drugs of Digitalis lanata Ehrh].
PubMed:Rapid and sensitive high-resolution procedure for digitalis glycoside analysis by derivatization liquid chromatography.
PubMed:Comparative study of the cardiac and peripheral vascular effects of strophantin K and lanatoside C in coronary heart disease.
PubMed:Therapeutic and toxic lanatoside C serum concentrations in hospital patients.
PubMed:[Biliary and urinary elimination of desacetyl-lanatoside C in anesthetized guinea pigs].
PubMed:[Subcellular distribution of desacetyl-lanatoside C, ouabain and digitoxin in the liver of awake guinea pigs].
PubMed:[Subcellular distribution of desacetyl-lanatoside C in the isolated guinea-pig heart].
PubMed:[Influence of desacetil lanatoside C glycoside upon the electrocardiogram, arterial blood pressure and electrolites in animals under experimental hypoxia (author's transl)].
PubMed:Letter: The double peak in the plasma-drug curve after oral digoxin and lanatoside C.
PubMed:[Quantitative determination of lanatoside C during chemical toxicological study. II].
PubMed:[The action of deacetyl lanatoside C on the contraction of isolated rat uterus].
PubMed:[On the National Institute of Hygienic Sciences Standard (the Japanese Pharmacopoeia Standard) "Lanatoside C reference Standard" (author's transl)].
PubMed:[Eosinophilia in the course of lanatoside C and quinidine treatment as the sole sign of drug hypersensitivity].
PubMed:[Clinical study of a new digitalic drug in 50 patients: deacetyl lanatoside C].
PubMed:[Extraction of digitoxin, oleandrin and lanatoside C with organic solvents].
PubMed:[Isolation and identification of lanatoside C in cadaveric material. I].
PubMed:[Clinical study of a new digitalic drug: desacetyl-lanatoside C].
PubMed:[Clinical study of a new cardiotonic drug, desacetyl-lanatoside C].
PubMed:[Influence of lanatoside C on the normal heart].
PubMed:[Lanatoside C and the adrenergic beta receptor blocker 39,089-Ba in hyperthyroid patients].
PubMed:Cat assay for the emetic action of digitalis and related glycosides (digitoxin, digoxin, lanatoside C, ouabain and calactin).
PubMed:[Behavior of cardiac glycosides in human organism. A review based on the example of digoxin and lanatoside C].
PubMed:[Chromatographic isolation and direct spectrofluorimetric determination on the chromatogram of medicines in micro amounts. 3. Study of tablets containing dixogin, digitoxin, acetyldigitoxin and lanatoside C].
PubMed:Investigation on changes in complex of cardiac glycosides under the influence of fungi parasitizing on foxgloves. II. Phyllosticta digitalis--transformation of lanatoside C.
PubMed:Interactions of lanatoside C and potassium on atrioventricular conduction in rabbits.
PubMed:[Desacetyl-lanatoside C: therapeutic effect in congestive heart failure].
PubMed:[Effectiveness of the use of desacetyl-lanatoside C in the treatment of cardiac insufficiency].
PubMed:[Influence of the inotropic effect of lanatoside C on the cardiac function and mechanism of mitral valve closure in patients with sinus rhythm].
PubMed:[The treatment of cardiac insufficiency with desacetyl-lanatoside C].
PubMed:[Acute myocardial infarct complicated by atrio-ventricular block. Hemodynamic effects of electrosystolic drive and lanatoside C].
PubMed:[Hemodynamic evaluation of the inotropic effect of lanatoside C. Patients with electro-paced chronic auriculo-ventricular block].
PubMed:The action of MJ1999 on the lethal effects of lanatoside C and ouabain in intact dogs.
PubMed:[Lanatoside C].
PubMed:[Comparison of the onset of the effect of G-strophanthin and lanatoside C in healthy persons].
PubMed:A study on the effect of lanatoside C on ventricular automaticity in man.
PubMed:Long-term cardiac pacing. Experience of fixed-rate pacing with an endocardial electrode in 260 patients. XIV. The effect of lanatoside C on ventricular automaticity in man.
PubMed:[Practical usefulness of the lanatoside C test in the diagnosis of rheumatic carditis].
PubMed:[Plasmatic concentrations of tritiated desacetyl-lanatoside C after intravenous and intramuscular injections in cardiopathic subjects].
PubMed:[Comparative evaluation, by the polygraphic method, of the effect of proscillaridine A and desacetyl-lanatoside C in normal subjects].
PubMed:[Biometric study of the changes of the mechanical phases of the cardiac cycle induced by intravenous desacetyl-lanatoside C in normal humans].
PubMed:[Influence of the maintenance dosage on urinary elimination of an average standard digitalization dose of tritiated desacetyl-lanatoside C in normal subjects and in fibrillating cardiopathic subjects].
PubMed:[Action of desacetyl-lanatoside C on acetylcholinesterase activity of the rat myocardium].
PubMed:[Comparison between blood levels, distribution in tissues and urinary elimination of desacetyl-lanatoside C labelled with tritium in the dog after intravenous and oral administration].
PubMed:[Clinical experience on Desacetyl-lanatoside C].
PubMed:[On the advantages of the use of desacetyl-lanatoside C in cardiokinetic therapy].
PubMed:[On some immediate effects of the intravenous administration of desacetyl-lanatoside C in aged subjects].
PubMed:[Extracellular concentrations of potassium and fixation of tritium-labelled desacetyl-lanatoside C in isolated guinea pig heart].
PubMed:Emesis in birds.
PubMed:[Calculation of doses of lanatoside C for maintenance treatment in cardiologic practice].
PubMed:[Infantile cardiac insufficiency of bronchopneumopathic origin. Treatment with desacetyl-lanatoside C].
PubMed:[The bradycardiac effect of oral administration of an overload of desacetyl-lanatoside C].
PubMed:[Cardenolide glycosides. XVI. Studies on the stability of lanatoside C and of the complex of lanatosides ABC in drug forms].
PubMed:[First studies on desacetyl-lanatoside C labeled with tritium: concentration of glycoside in tissues, blood and urine in experimental animals (dog)].
PubMed:[Diacetyl-lanatoside C in the therapy of cardio-circulatory decompensation in the aged].
PubMed:[Desacetyl-lanatoside-C in heart diseases].
PubMed:[Experiences with desacetyl-lanatoside C in treatment and in preparation for surgery of surgical heart disease patients].
PubMed:[On the use of desacetyl-lanatoside C in therapy of uncompensated heart diseases. Clinical contribution].
PubMed:[Clinical experiences with desacetyl-lanatoside-C].
PubMed:[DESACETYL-LANATOSIDE C IN THERAPY OF HEART DECOMPENSATION].
PubMed:[RESULTS OF A CARDIOTONIC THERAPY WITH DESACETYL-LANATOSIDE C].
PubMed:[Ballistocardiographic studies on the effect of lanatoside C on the normal heart].
PubMed:[ON THE USE OF DESACETYL-LANATOSIDE C IN THE TREATMENT OF CARDIAC INSUFFICIENCY].
PubMed:[PROPOSALS FOR DAB 7. LANATOSIDE C].
PubMed:[STUDIES OF THE EFFECT OF LANATOSIDE C ON THE HYPOTHERMIC HEART].
PubMed:[CONTRIBUTION TO THE CLINICAL STUDY OF THE THERAPEUTIC EFFECTS OF DESACETYL-LANATOSIDE C].
PubMed:[CLINICAL EXPERIENCE WITH A NEW CARDIOACTIVE GLYCOSIDE: DESACETYL-LANATOSIDE C].
PubMed:[HEART THERAPY WITH LANATOSIDE C, THEOPHYLLINE AND VITAMIN B FACTORS].
PubMed:[CARDENOLID GLYCOSIDES. 8. ALKALINE DEGRADATION OF LANATOSIDE C].
PubMed:[OBSERVATIONS ON THE ACTIVITY OF A NEW DIGITALIC PRODUCT (DESACETYL-LANATOSIDE C) IN THE TREATMENT OF CARDIAC INSUFFICIENCY].
PubMed:[RAPID DIGITALIZATION AND MAINTENANCE WITH DESACETYL-LANATOSIDE C; CLINICAL OBSERVATIONS].
PubMed:EFFECTS OF INTRAVENOUS LANATOSIDE C ON THE PULMONARY CIRCULATION IN PATIENTS WITH PULMONARY HYPERTENSION.
PubMed:[ON THE CLINICAL USE OF DESACETYL-LANATOSIDE C].
PubMed:Role of calcium and lanatoside C in increasing oxygen consumption in human myocardial tissue slices.
PubMed:[Clinical experiences with a lanatoside C preparation soluble in the small intestine].
PubMed:[Lanatoside C in hospital therapeutics].
PubMed:[Effects of desacetyl-lanatoside C on cardiac output, coronary flow and O2 consumption of the dog heart in situ].
PubMed:[Arterial concentration, arteriovenous difference in the coronary blood and organ distribution of C14-labeled-lanatoside C after rapid intravenous injection].
PubMed:[Contribution to cardiotonic therapy by oral route with deacetyl-lanatoside C and diethlamino-phenyl-ethylbarbiturate].
PubMed:[Effects of the administration of lanatoside C in cardiocirculatory decompensation].
PubMed:[Saturation therapy with lanatoside C].
PubMed:Effects of intravenous lanatoside-C upon cardiodynamics in patients with mitral stenosis and regular sinus rhythm.
PubMed:[Clinical trial of a new oral preparation of Lanatoside C ("Cedilanid Space Tab")].
PubMed:[Oxygen consumption and glycogen content of the liver and right and left ventricles of the heart of rats treated with lanatoside C of digitalis].
PubMed:[Oxygen consumption and glycogen content of the liver and right and left ventricles of the heart of rats treated with testosterone propionate and lanatoside C of digitalis].
PubMed:The effect of Lanatoside-C on the reponse of the human cardiac output to walking exercise.
PubMed:Effects of lanatoside C on cardiovascular hemodynamics; acute digitalizing doses in subjects with normal hearts and with heart disease without failure.
PubMed:The duration of action of some cardiac glycosides and aglycones in the guinea-pig.
PubMed:[Lanatoside C therapy of cardiac insufficiency highly sensitive to glycosides].
PubMed:[Pharmacological and clinical considerations on the association ATP-cardiac glycosides (lanatoside C, strophanthin) in the treatment of arteriosclerotic heart disease].
PubMed:Intramuscular desacetyl lanatoside C: a safe and practical method of parenteral digitalization.
PubMed:[The effects of digitalis (lanatoside-C and digitoxin) on electrocardiogram and myocardium in guinea pigs].
PubMed:Chronic cardiac insufficiency; prolonged oral lanatoside C therapy.
PubMed:[Role of lanatoside C in current heart therapy].
PubMed:[Mechanism of arterial hypertension induced by lanatoside C in the guinea pig].
PubMed:[Effect of hemorrhage & ligation of portal vein on the lethal dose of digitalin & lanatoside C in guinea pig].
PubMed:[Treatment of cardiac insufficiency with simultaneously administered lanatoside C & scillaren].
PubMed:[Actions of adenosine. III. Influence of adenosine on the effects of lanatoside C].
PubMed:[Cardiopulmonary hemodynamic behavior after intravenous administration of lanatoside C in mitral valve disease].
PubMed:The hemodynamic response to lanatoside C of dogs with experimental aortic-caval fistulas.
PubMed:A comparison of effects of lanatoside C and digoxigenin on heart muscle.
PubMed:[Behavior of several enzymatic activities of the rabbit heart treated with cardiac glycosides. II. Variations in the succinic dehydrogenase and cytochrome oxidase activity of the rabbit heart after a single dose and after prolonged administration of lanatoside C].
PubMed:[Spectrophotometric method for the determination of cardioactive glycosides. III. Calibration curve for acetyldigitoxin, lanatoside C and strophanthoside K].
PubMed:[An unidentified glycosidic substance in lanatoside C preparations].
PubMed:Studies on myocardial metabolism. V. The effects of lanatoside-C on the metabolism of the human heart.
PubMed:Studies of the renal circulation and renal function in mitral valvular disease. IV. The effect of a single intravenous injection of lanatoside C.
PubMed:[Effects of adrenal hormones on the cardiotonic and toxic actions of lanatoside C].
PubMed:[Effect of lanatoside C on renal blood flow, diuresis and sodium excretion in mitral stenosis].
PubMed:[Effects of lanatoside C on the pulmonary circulation in mitral valve defect].
PubMed:The excretory products of lanatoside C and digitoxin in the rat.
PubMed:Action of dinitrophenol and lanatoside C on the canine heart-lung preparation.
PubMed:Use of lanatoside C (cedilanid) in cardiac arrythmias and congestive failure.
PubMed:[Lanatoside C, ther. of heart disease in pregnancy].
PubMed:Factors affecting the action of lanatoside C on the potassium content of isolated perfused guinea pig hearts.
PubMed:The effect of lanatoside C on the circulatory and ventilatory changes of chronic rheumatic hear disease with mitral stenosis.
PubMed:The effect of potassium depletion induced by desoxycorticosterone acetate on the lethal dose of lanatoside C in dogs: relationship of plasma levels, skeletal and cardiac muscle potassium content to the lethal dose.
PubMed:[Pharmacotherapy of heart and blood circulation in childhood with special reference to lanatoside C (cedilanid)].
PubMed:[Peroral continous therapy of the chronic muscular cardiac insufficiency with lanatoside C].
PubMed:Increase in oxygen consumption of human cardiac muscle incubated with lanatoside C.
PubMed:The circulatory and ventilatory changes in chronic pulmonary disease as affected by lanatoside C.
PubMed:The usefulness of intravenous lanatoside C in paroxysmal ventricular tachycardia not due to myocardial infarction.
PubMed:Lanatoside C in the treatment of supraventricular tachycardia.
PubMed:[Lanatoside C therapy of cardiac insufficiency].
PubMed:Renal excretion of Lanatoside C. in the rat.
PubMed:[Effect of lanatoside C on circulatory insufficiency].
PubMed:[Effect of lanatoside C in patients with sinusal rhythm].
PubMed:Some common arrhythmias and their treatment with lanatoside C (cedilanid).
PubMed:[Effect of lanatoside C in auricular flutter and fibrillation].
PubMed:Treatment of cardiac emergencies with K-strophanthoside and lanatoside C.
PubMed:[Peripheral effect of lanatoside C on water hemato-tissular exchange. I. In normal subjects].
PubMed:The rate of disappearance of lanatoside C. and digitoxin from the blood of rats.
PubMed:Treatment of paroxysmal supraventricular tachycardia with lanatoside C.
PubMed:Study of the rate of disappearance of a digitalis glycoside, lanatoside C, from the blood of man.
PubMed:Studies on the circulation in man; the effect of cedilanid (lanatoside C) on cardiac output and blood pressure in the pulmonary circulation in patients with compensated and decompensated heart disease.
PubMed:A STUDY OF THE RATE OF DISAPPEARANCE OF A DIGITALIS GLYCOSIDE (LANATOSIDE C.) FROM THE BLOOD OF MAN.
PubMed:[Therapeutic use of lanatoside C].
PubMed:The delay in the action of digitalis glycoside, lanatoside C.
PubMed:[Not Available].
PubMed:Effect of lanatoside C on the circulation of patients with congestive failure; a study using catheterization of the right side of the heart.
PubMed:Observations concerning the influence of potassium upon the action of a digitalis glycoside (lanatoside C).
PubMed:Lanatoside C in the treatment of persistent paroxysmal auricular tachycardia.
PubMed:Effect of lanotoside C upon the survival of rats subjected to severe hypothermia.
PubMed:Comparative study on the use of the purified digitalis glycosides, digoxin, digitoxin, and lanatoside C, for the management of ambulatory patients with congestive heart failure.
PubMed:Employment of the embryonic duck heart for the detection of minute amounts of a digitalis glycoside (lanatoside C).
PubMed:Lanatoside C (cedilanid).
PubMed:The use of lanatoside C in the treatment of congestive heart failure.
PubMed:The intravenous administration of lanatoside C to patients taking maintenance doses of folia digitalis up to the date of hospitalization with recurrent congestive heart failure.
 
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