EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

9H-xanthen-9-one, 2-beta-D-glucopyranosyl-1,3,6,7-tetrahydroxy- (9CI)

Supplier Sponsors

CAS Number: 4773-96-0Picture of molecule3D/inchi
Other(deleted CASRN):99331-60-9
Nikkaji Web:J15.735J
XlogP3-AA:-0.40 (est)
Molecular Weight:422.34366000
Formula:C19 H18 O11
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic ingredient for skin protecting
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 842.70 °C. @ 760.00 mm Hg (est)
Flash Point: 578.00 °F. TCC ( 303.60 °C. ) (est)
logP (o/w): 0.130 (est)
Soluble in:
 water, 467.8 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin protecting agents
Alfa Biotechnology
For experimental / research use only.
Mangiferin 98%
BOC Sciences
For experimental / research use only.
For experimental / research use only.
Mangiferin (HPLC) ≥90%
Sigma-Aldrich: Sigma
For experimental / research use only.
Mangiferin from Mangifera indica bark
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 2300 ug/kg
Problemi na Vutreshnata Meditsina. Problems of Internal Medicine. Vol. 8(2), Pg. 109, 1980.

intraperitoneal-rat LD50 365 mg/kg
Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1838, 1972.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic ingredient for skin protecting
Recommendation for mangiferin usage levels up to:
 not for fragrance use.
Recommendation for mangiferin flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281647
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
RTECS:OP1927800 for cas# 4773-96-0
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281647
Pubchem (sid):135023010
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C10077
HMDB (The Human Metabolome Database):HMDB34410
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 mango bark
Search Trop Picture
 mango fruit
Search Trop Picture
9H-xanthen-9-one, 2-beta-D-glucopyranosyl-1,3,6,7-tetrahydroxy- (9CI)


PubMed:The Rhizome Mixture of Anemarrhena asphodeloides and Coptidis chinensis Ameliorates Acute and Chronic Colitis in Mice by Inhibiting the Binding of Lipopolysaccharide to TLR4 and IRAK1 Phosphorylation.
PubMed:Mangiferin in cancer chemoprevention and treatment: pharmacokinetics and molecular targets.
PubMed:Mangiferin ameliorates colitis by inhibiting IRAK1 phosphorylation in NF-κB and MAPK pathways.
PubMed:Evaluation of extraction methods for preparative scale obtention of mangiferin and lupeol from mango peels (Mangifera indica L.).
PubMed:Iriflophenone-3-C-glucoside from Cyclopia genistoides: isolation and quantitative comparison of antioxidant capacity with mangiferin and isomangiferin using on-line HPLC antioxidant assays.
PubMed:The genus Anemarrhena Bunge: A review on ethnopharmacology, phytochemistry and pharmacology.
PubMed:Ultrasound-assisted extraction of Mangiferin from Mango (Mangifera indica L.) leaves using response surface methodology.
PubMed:Antioxidant properties and hyphenated HPLC-PDA-MS profiling of Chilean Pica mango fruits (Mangifera indica L. Cv. piqueño).
PubMed:Beneficial effects of mangiferin isolated from Salacia chinensis on biochemical and hematological parameters in rats with streptozotocin-induced diabetes.
PubMed:Protective nature of mangiferin on oxidative stress and antioxidant status in tissues of streptozotocin-induced diabetic rats.
PubMed:Soya phospholipid complex of mangiferin enhances its hepatoprotectivity by improving its bioavailability and pharmacokinetics.
PubMed:Mangiferin from Salacia chinensis prevents oxidative stress and protects pancreatic β-cells in streptozotocin-induced diabetic rats.
PubMed:Comparison of microwave-assisted and conventional extraction of mangiferin from mango (Mangifera indica L.) leaves.
PubMed:Antioxidant markers based TLC-DPPH differentiation on four commercialized botanical sources of Shankhpushpi (A Medhya Rasayana): A preliminary assessment.
PubMed:Food ingredient extracts of Cyclopia subternata (Honeybush): variation in phenolic composition and antioxidant capacity.
PubMed:Polyphenolic and vitamin C contents and antioxidant activities of aqueous extracts from mature-green and ripe fruit fleshes of Mangifera sp.
PubMed:Evaluation of genotoxicity and DNA protective effects of mangiferin, a glucosylxanthone isolated from Mangifera indica L. stem bark extract.
PubMed:Gentiana asclepiadea exerts antioxidant activity and enhances DNA repair of hydrogen peroxide- and silver nanoparticles-induced DNA damage.
PubMed:Development and application of an enzyme-linked immunosorbent assay for specific detection of mangiferin content in various cultivars of Mangifera indica leaves using anti-mangiferin polyclonal antibody.
PubMed:Mangiferin decreases plasma free fatty acids through promoting its catabolism in liver by activation of AMPK.
PubMed:Mangiferin glucuronidation: important hepatic modulation of antioxidant activity.
PubMed:Beneficial effects of mangiferin on hyperlipidemia in high-fat-fed hamsters.
PubMed:Anti-diabetic effects of TongGuanWan, a Chinese traditional herbal formula, in C57BL/KsJ-db/db mice.
PubMed:Identification and quantification of phenolic compounds in bambangan (Mangifera pajang Kort.) peels and their free radical scavenging activity.
PubMed:Characterization of bioactive compounds from raw and ripe Mangifera indica L. peel extracts.
PubMed:The phenolic acids from bacterial degradation of the mangiferin aglycone are quantified in the feces of pigs after oral ingestion of an extract of Cyclopia genistoides (honeybush tea).
PubMed:Mango extracts and the mango component mangiferin promote endothelial cell migration.
PubMed:Influences of harvest date and location on the levels of beta-carotene, ascorbic acid, total phenols, the in vitro antioxidant capacity, and phenolic profiles of five commercial varieties of mango (Mangifera indica L.).
PubMed:Effect of pre-drying treatments and storage on color and phenolic composition of green honeybush (Cyclopia subternata) herbal tea.
PubMed:In vitro effects of Mangifera indica and polyphenols derived on ABCB1/P-glycoprotein activity.
PubMed:Cytoprotective and antigenotoxic potential of Mangiferin, a glucosylxanthone against cadmium chloride induced toxicity in HepG2 cells.
PubMed:Mangiferin and hesperidin metabolites are absorbed from the gastrointestinal tract of pigs after oral ingestion of a Cyclopia genistoides (honeybush tea) extract.
PubMed:Characterization and quantitation of polyphenolic compounds in bark, kernel, leaves, and peel of mango (Mangifera indica L.).
PubMed:Salacia root, a unique Ayurvedic medicine, meets multiple targets in diabetes and obesity.
PubMed:Effects of the mango components mangiferin and quercetin and the putative mangiferin metabolite norathyriol on the transactivation of peroxisome proliferator-activated receptor isoforms.
PubMed:Effect of species variation and processing on phenolic composition and in vitro antioxidant activity of aqueous extracts of Cyclopia spp. (Honeybush Tea).
PubMed:A comparative study on the antimutagenic properties of aqueous extracts of Aspalathus linearis (rooibos), different Cyclopia spp. (honeybush) and Camellia sinensis teas.
PubMed:Evaluation of the genotoxic potential of Mangifera indica L. extract (Vimang), a new natural product with antioxidant activity.
PubMed:Use of NIRS for quantification of mangiferin and hesperidin contents of dried green honeybush (Cyclopia genistoides) plant material.
PubMed:Neuroprotection by two polyphenols following excitotoxicity and experimental ischemia.
PubMed:Phenolic metabolites from honeybush tea (Cyclopia subternata).
PubMed:Identification of flavonol and xanthone glycosides from mango (Mangifera indica L. Cv. "Tommy Atkins") peels by high-performance liquid chromatography-electrospray ionization mass spectrometry.
PubMed:Salacia reticulata and its polyphenolic constituents with lipase inhibitory and lipolytic activities have mild antiobesity effects in rats.
PubMed:Isolation and quantitative analysis of phenolic antioxidants, free sugars, and polyols from mango (Mangifera indica L.) stem bark aqueous decoction used in Cuba as a nutritional supplement.
has effects on central nervous system; an antidiabetic agent. Constit. of Mangifera indica (mango)
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy