EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

saponarin
isovitexin-7-O-glucoside

Supplier Sponsors

Name:5-hydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-7-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]o
CAS Number: 20310-89-8Picture of molecule3D/inchi
FDA UNII: 3081Z76OX9
Nikkaji Web:J94.482C
XlogP3-AA:-1.60 (est)
Molecular Weight:594.52410000
Formula:C27 H30 O15
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 919.50 °C. @ 760.00 mm Hg (est)
Flash Point: 582.00 °F. TCC ( 305.40 °C. ) (est)
logP (o/w): -1.210 (est)
Soluble in:
 water, 4.116e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
4H-1-Benzopyran-4-one,6-b-D-glucopyranosyl-7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)- 95%
ExtraSynthese
For experimental / research use only.
Saponarin (HPLC) ≥98%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for saponarin usage levels up to:
 not for fragrance use.
 
Recommendation for saponarin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :441381
National Institute of Allergy and Infectious Diseases:Data
5-hydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-7-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]o
Chemidplus:0020310898
 
References:
 5-hydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-7-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]o
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):441381
Pubchem (sid):135228635
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
KEGG (GenomeNet):C08064
HMDB (The Human Metabolome Database):Search
FooDB:FDB016655
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 barley leaf
Search Trop Picture
 barley shoot
Search Trop Picture
 cucumber
Search Trop Picture
 
Synonyms:
4H-1-benzopyran-4-one, 3-((6-O-(6-deoxy-beta-L-mannofuranosyl)-beta-O-galactofuranosyl)oxy)-7-((6-deoxy-beta-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-
 saponaretin-7-O-glucoside
isovitexin-7-O-glucoside
 

Articles:

PubMed:Preparation of two flavonoid glycosides with unique structures from barley seedlings by membrane separation technology and preparative high-performance liquid chromatography.
PubMed:Saponarin from barley sprouts inhibits NF-κB and MAPK on LPS-induced RAW 264.7 cells.
PubMed:Protective effects of the apigenin-O/C-diglucoside saponarin from Gypsophila trichotoma on carbone tetrachloride-induced hepatotoxicity in vitro/in vivo in rats.
PubMed:Hepatoprotective and antioxidant effects of saponarin, isolated from Gypsophila trichotoma Wend. on paracetamol-induced liver damage in rats.
PubMed:First synthesis of saponarin, 6-C- and 7-O-di-β-D-glucosylapigenin.
PubMed:Flavonoids with potent antioxidant activity found in young green barley leaves.
PubMed:Bioflavonoid profile of citrus juices from Greece.
PubMed:HPLC determination of flavonoid glycosides in Mongolian Dianthus versicolor Fisch. (Caryophyllaceae) compared with quantification by UV spectrophotometry.
PubMed:Hepatoprotective effects of saponarin, isolated from Gypsophila trichotoma Wend. on cocaine-induced oxidative stress in rats.
PubMed:Flavonoid C- and O-glycosides from the Mongolian medicinal plant Dianthus versicolor Fisch.
PubMed:Distribution of free amino acids, flavonoids, total phenolics, and antioxidative activities of Jujube (Ziziphus jujuba) fruits and seeds harvested from plants grown in Korea.
PubMed:Quantification of flavonoid glycosides in an aqueous extract from the traditional Mongolian medicinal plant Dianthus versicolor FISCH.
PubMed:Phytochemical investigation and biological studies of Bombax malabaricum flowers.
PubMed:Extracts from the Mongolian traditional medicinal plants Dianthus versicolorFisch. and Lilium pumilum Delile stimulate bile flow in an isolated perfused rat liver model.
PubMed:The effect of isosaponarin isolated from wasabi leaf on collagen synthesis in human fibroblasts and its underlying mechanism.
PubMed:Proteome and flavonoid analysis reveals distinct responses of epidermal tissue and whole leaves upon UV-B radiation of barley (Hordeum vulgare L.) seedlings.
PubMed:Dolichandroside A, a new alpha-glucosidase inhibitor and DPPH free-radical scavenger from Dolichandrone falcata seem.
PubMed:Hypoglycemic activity of the antioxidant saponarin, characterized as alpha-glucosidase inhibitor present in Tinospora cordifolia.
PubMed:Further knowledge on barley (Hordeum vulgare L.) leaves O-glycosyl-C-glycosyl flavones by liquid chromatography-UV diode-array detection-electrospray ionisation mass spectrometry.
PubMed:Antioxidant activity of flavonoids isolated from young green barley leaves toward biological lipid samples.
PubMed:Phenolic constituents in dried flowers of aloe vera (Aloe barbadensis) and their in vitro antioxidative capacity.
PubMed:Flavonoid biosynthesis in barley primary leaves requires the presence of the vacuole and controls the activity of vacuolar flavonoid transport.
PubMed:Antioxidant phenolic glucosides from Gentiana piasezkii.
PubMed:Contribution of phenolic compounds to the UV-B screening capacity of developing barley primary leaves in relation to DNA damage and repair under elevated UV-B levels.
PubMed:The mis-identification of the major antioxidant flavonoids in young barley (Hordeum vulgare) leaves.
PubMed:Jasmonate-induced changes in flavonoid metabolism in barley (Hordeum vulgare) leaves.
PubMed:Flavone glucoside uptake into barley mesophyll and Arabidopsis cell culture vacuoles. Energization occurs by H(+)-antiport and ATP-binding cassette-type mechanisms.
PubMed:Acylated flavone C-glycosides from Cucumis sativus.
PubMed:Antihepatotoxic C-glycosylflavones from the leaves of Allophyllus edulis var. edulis and gracilis.
PubMed:Chemical constituents of gentianaceae XXVIII: flavonoids of Enicostemma hyssopifolium (Willd.) Verd.
PubMed:Uridinediphosphate-glucose: Isovitexin 7-O-glucosyltransferase from barley protoplasts: Subcellular localization.
PubMed:The flavonoid constituents of barley (Horedum vulgare). I. Saponarin.
 
Notes:
None found
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