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sparteine sulfate anhydrous
7,14-methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-, sulfate (1:1) (9CI)

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Name:(1R,2S,9R,10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecane;sulfuric acid
CAS Number: 299-39-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:206-078-4
FDA UNII: 3D76XVF9R0
Molecular Weight:332.46396000
Formula:C15 H28 N2 O4 S
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 6.67E+05mg/L @ 15 °C (exp)
 water, 3.801e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Sparteine sulfate >98%
ExtraSynthese
For experimental / research use only.
Sparteine Sulfate Anhydrous
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
parenteral-frog LDLo 375 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 431, 1926.

intraperitoneal-guinea pig LDLo 42 mg/kg
Journal of Agricultural Research Vol. 32, Pg. 51, 1926.

intraperitoneal-mouse LD50 43 mg/kg
Journal of Medicinal Chemistry. Vol. 20, Pg. 1668, 1977.

intravenous-mouse LD50 15 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: STIFFNESS
Japanese Journal of Pharmacology. Vol. 16, Pg. 353, 1966.

oral-mouse LD50 350 mg/kg
BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 1497, 1980.

intravenous-rat LD50 30400 ug/kg
BEHAVIORAL: STIFFNESS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Japanese Journal of Pharmacology. Vol. 16, Pg. 353, 1966.

Dermal Toxicity:
subcutaneous-mouse LD50 117 mg/kg
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: STIFFNESS
Japanese Journal of Pharmacology. Vol. 16, Pg. 353, 1966.

subcutaneous-rabbit LDLo 80 mg/kg
VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION
Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 431, 1926.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for sparteine sulfate anhydrous usage levels up to:
 not for fragrance use.
 
Recommendation for sparteine sulfate anhydrous flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :9293
National Institute of Allergy and Infectious Diseases:Data
(1R,2S,9R,10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecane;sulfuric acid
Chemidplus:0000299398
 
References:
 (1R,2S,9R,10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecane;sulfuric acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):9293
Pubchem (sid):134975117
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 actospar
 depasan
(1R,2S,9R,10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecane;sulfuric acid
7,14-methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-, sulfate (1:1) (9CI)
 siarczan sparteiny
 spareng
 sparteine sulfate
 sparteine sulphate anhydrous
 sparteine, sulfate (1:1) (8CI)
 spartepur
 spartin
 spartocin
 spatym
 tocosamine sulfate
 tocosimplex
 
 
Notes:
a quinolizidine alkaloid isolated from several fabaceae including lupinus; spartium; and cytisus. it has been used as an oxytocic and an anti-arrhythmia agent. it has also been of interest as an indicator of cyp2d6 genotype.
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