EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

alpha-D-glucopyranoside, beta-D-fructofuranosyl O-alpha-D-galactopyranosyl-(1->6)-O-alpha-D-galactopyranosyl-(1->6)-

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CAS Number: 470-55-3Picture of molecule3D/inchi
Other(deleted CASRN):11036-79-6
ECHA EINECS - REACH Pre-Reg:207-427-3
FDA UNII: 25VX64653N
XlogP3:-8.00 (est)
Molecular Weight:666.58194000
Formula:C24 H42 O21
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point:1044.20 °C. @ 760.00 mm Hg (est)
Flash Point:1086.00 °F. TCC ( 585.30 °C. ) (est)
logP (o/w): -2.880 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
BOC Sciences
For experimental / research use only.
Stachyose - 70%
For experimental / research use only.
For experimental / research use only.
Jiangyin Healthway
New functional food ingredients
Santa Cruz Biotechnology
For experimental / research use only.
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
natural substances and extractives
Recommendation for stachyose usage levels up to:
 not for fragrance use.
Recommendation for stachyose flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):470-55-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :91455
National Institute of Allergy and Infectious Diseases:Data
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):91455
Pubchem (sid):135048506
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C01613
HMDB (The Human Metabolome Database):HMDB03553
VCF-Online:VCF Volatile Compounds in Food
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
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alpha-D-glucopyranoside, beta-D-fructofuranosyl O-alpha-D-galactopyranosyl-(1->6)-O-alpha-D-galactopyranosyl-(1->6)-


PubMed:Oligosaccharides composition in eight food legumes species as detected by high-resolution mass spectrometry.
PubMed:Application of ultrasound for enhanced extraction of prebiotic oligosaccharides from selected fruits and vegetables.
PubMed:Metabolomic shifts in Brassica napus lines with enhanced BnPLC2 expression impact their response to low temperature stress and plant pathogens.
PubMed:Thermostability of Probiotics and Their α -Galactosidases and the Potential for Bean Products.
PubMed:A reliable and rapid method for soluble sugars and RFO analysis in chickpea using HPAEC-PAD and its comparison with HPLC-RI.
PubMed:Optimization of extracting stachyose from Stachys floridana Schuttl. ex Benth by response surface methodology.
PubMed:Changes due to cooking and sterilization in low molecular weight carbohydrates in immature seeds of five cultivars of common bean.
PubMed:Stachyose-enriched α-galacto-oligosaccharides regulate gut microbiota and relieve constipation in mice.
PubMed:Inhibitory effects of resistant starch (RS3) as a carrier for stachyose on dextran sulfate sodium-induced ulcerative colitis in C57BL/6 mice.
PubMed:Compositional equivalence of DAS-444Ø6-6 (AAD-12 + 2mEPSPS + PAT) herbicide-tolerant soybean and nontransgenic soybean.
PubMed:Effect of controlled lactic acid fermentation on selected bioactive and nutritional parameters of tempeh obtained from unhulled common bean (Phaseolus vulgaris) seeds.
PubMed:Adaptation of the AOAC 2011.25 integrated total dietary fiber assay to determine the dietary fiber and oligosaccharide content of dry edible beans.
PubMed:Biotechnological potential of microbial α-galactosidases.
PubMed:Isolation, characterization, and hepatoprotective effects of the raffinose family oligosaccharides from Rehmannia glutinosa Libosch.
PubMed:Global characterization of neutral saccharides in crude and processed Radix Rehmanniae by hydrophilic interaction liquid chromatography tandem electrospray ionization time-of-flight mass spectrometry.
PubMed:Genotype and growing environment interaction shows a positive correlation between substrates of raffinose family oligosaccharides (RFO) biosynthesis and their accumulation in chickpea ( Cicer arietinum L.) seeds.
PubMed:Characterization of functional, safety, and gut survival related characteristics of Lactobacillus strains isolated from farmhouse goat's milk cheeses.
PubMed:Classification of distinct seed carbohydrate profiles in soybean.
PubMed:Nutritional potential of rice bean (Vigna umbellata): an underutilized legume.
PubMed:Manninotriose is a major carbohydrate in red deadnettle (Lamium purpureum, Lamiaceae).
PubMed:Bayesian statistical approaches to compositional analyses of transgenic crops 2. Application and validation of informative prior distributions.
PubMed:Characterization of lactic acid bacteria from naturally-fermented Manzanilla Aloreña green table olives.
PubMed:Composition of two Spanish common dry beans (Phaseolus vulgaris), 'Almonga' and 'Curruquilla', and their postprandial effect in type 2 diabetics.
PubMed:Functional analysis of family GH36 α-galactosidases from Ruminococcus gnavus E1: insights into the metabolism of a plant oligosaccharide by a human gut symbiont.
PubMed:Levansucrase and sucrose phoshorylase contribute to raffinose, stachyose, and verbascose metabolism by lactobacilli.
PubMed:Effect of CMV infection and high temperatures on the enzymes involved in raffinose family oligosaccharide biosynthesis in melon plants.
PubMed:Changes in growth and survival of Bifidobacterium by coculture with Propionibacterium in soy milk, cow's milk, and modified MRS medium.
PubMed:Controlled exogenous enzyme imbibition and activation in whole chickpea seed enzyme reactor (SER).
PubMed:Purification and characterization of α-galactosidase from white chickpea (Cicer arietinum).
PubMed:Comparing anti-hyperglycemic activity and acute oral toxicity of three different trivalent chromium complexes in mice.
PubMed:Characterization of a protease-resistant α-galactosidase from the thermophilic fungus Rhizomucor miehei and its application in removal of raffinose family oligosaccharides.
PubMed:A simple and accurate method for determining wheat grain fructan content and average degree of polymerization.
PubMed:Effects of non-fermented and fermented soybean milk intake on faecal microbiota and faecal metabolites in humans.
PubMed:Study of influential factors on oligosaccharide formation by fructosyltransferase activity during stachyose hydrolysis by Pectinex ultra SP-L.
PubMed:Reduction of α-galactoside content in red gram (Cajanus cajan L.) upon germination followed by heat treatment.
PubMed:Quantification of fructans, galacto-oligosacharides and other short-chain carbohydrates in processed grains and cereals.
PubMed:Purification and characterization of Aspergillus terreus α-galactosidases and their use for hydrolysis of soymilk oligosaccharides.
PubMed:Molecular description and industrial potential of Tn6098 conjugative transfer conferring alpha-galactoside metabolism in Lactococcus lactis.
PubMed:Changes in the contents of sugars and organic acids during the ripening and storage of sufu, a traditional Oriental fermented product of soybean cubes.
PubMed:Effects of roasting on taste-active compounds of Turkish hazelnut varieties ( Corylus avellana L.).
PubMed:Naturally occurring prebiotic oligosaccharides in poultry feed mixtures.
PubMed:An alpha-galactosidase from an acidophilic Bispora sp. MEY-1 strain acts synergistically with beta-mannanase.
PubMed:Isolation, characterization, and immunological effects of alpha-galacto-oligosaccharides from a new source, the herb Lycopus lucidus Turcz.
PubMed:Studies on the incorporation of velvet bean (Mucuna pruriens var. utilis) as an alternative protein source in poultry feed and its effect on growth performance of broiler chickens.
PubMed:Enhanced growth of lactobacilli in soymilk upon immobilization on agrowastes.
PubMed:Sucrose and raffinose family oligosaccharides (RFOs) in soybean seeds as influenced by genotype and growing location.
PubMed:A genomic approach to nutritional, pharmacological and genetic issues of faba bean (Vicia faba): prospects for genetic modifications.
PubMed:Effect of cooking time on some nutrient and antinutrient components of bambaragroundnut seeds.
PubMed:Molecular cloning and expression of a novel protease-resistant GH-36 alpha-galactosidase from Rhizopus sp. F78 ACCC 30795.
PubMed:Chemical composition and in vitro polysaccharide fermentation of different beans (Phaseolus vulgaris L.).
PubMed:Soybean whey enhance mineral balance and caecal fermentation in rats.
PubMed:Evaluation of agrowastes as immobilizers for probiotics in soy milk.
PubMed:Enhancement of alpha- and beta-galactosidase activity in Lactobacillus reuteri by different metal ions.
PubMed:Metabolite profiling of two novel low phytic acid (lpa) soybean mutants.
PubMed:Identification of oligosaccharides formed during stachyose hydrolysis by Pectinex Ultra SP-L.
PubMed:A novel protease-resistant alpha-galactosidase with high hydrolytic activity from Gibberella sp. F75: gene cloning, expression, and enzymatic characterization.
PubMed:Debaryomyces hansenii UFV-1 intracellular alpha-galactosidase characterization and comparative studies with the extracellular enzyme.
PubMed:Measurement of short-chain carbohydrates in common Australian vegetables and fruits by high-performance liquid chromatography (HPLC).
PubMed:Enzyme activities of lactic acid bacteria from a pearl millet fermented gruel (ben-saalga) of functional interest in nutrition.
PubMed:Novel process of fermenting black soybean [Glycine max (L.) Merrill] yogurt with dramatically reduced flatulence-causing oligosaccharides but enriched soy phytoalexins.
PubMed:Selection and optimization procedure of synbiotic for cholesterol removal.
PubMed:Chemical composition of glyphosate-tolerant soybean 40-3-2 grown in Europe remains equivalent with that of conventional soybean (Glycine max L.).
PubMed:Change in oligosaccharides during processing of soybean sheet.
PubMed:Saponin-containing subfractions of soybean molasses induce enteritis in the distal intestine of Atlantic salmon.
PubMed:Characterization of lactobacilli isolated from caper berry fermentations.
PubMed:Elevated atmospheric CO2 and strain of rhizobium alter freezing tolerance and cold-induced molecular changes in alfalfa (Medicago sativa).
PubMed:Characterisation and biochemical properties of predominant lactic acid bacteria from fermenting cassava for selection as starter cultures.
PubMed:Evaluation of soyasaponin, isoflavone, protein, lipid, and free sugar accumulation in developing soybean seeds.
PubMed:A novel thermostable alpha-galactosidase from the thermophilic fungus Thermomyces lanuginosus CBS 395.62/b: purification and characterization.
PubMed:Effect of industrial dehydration on the soluble carbohydrates and dietary fiber fractions in legumes.
PubMed:Soybean oligosaccharides. Potential as new ingredients in functional food.
PubMed:Identification of a novel alpha-galactosidase from the hyperthermophilic archaeon Sulfolobus solfataricus.
PubMed:Extracellular alpha-galactosidase from Debaryomyces hansenii UFV-1 and its use in the hydrolysis of raffinose oligosaccharides.
PubMed:Chemical components with health implications in wild and cultivated Mexican common bean seeds (Phaseolus vulgaris L.).
PubMed:In vivo measurement of flatulence and nutrient digestibility in dogs fed poultry by-product meal, conventional soybean meal, and low-oligosaccharide low-phytate soybean meal.
PubMed:Oligosaccharins of black gram (Vigna mungo L.) as affected by processing methods.
PubMed:Antinutritional factors and in vitro protein digestibility of improved haricot bean (Phaseolus vulgaris L.) varieties grown in Ethiopia.
PubMed:Diversity and technological properties of predominant lactic acid bacteria from fermented cassava used for the preparation of Gari, a traditional African food.
PubMed:Compositional variations for alpha-galactosides in different species of leguminosae, brassicaceae, and barley: a chemotaxonomic study based on chemometrics and high-performance capillary electrophoresis.
PubMed:Yeast (different sources and levels) as protein source in diets of reared piglets: effects on protein digestibility and N-metabolism.
PubMed:Amino acid, carbohydrate, and fat composition of soybean meals prepared at 55 commercial U.S. soybean processing plants.
PubMed:Reduction of non-digestible oligosaccharides in soymilk: application of engineered lactic acid bacteria that produce alpha-galactosidase.
PubMed:Molecular characterization, technological properties and safety aspects of enterococci from 'Hussuwa', an African fermented sorghum product.
PubMed:Alpha and beta-galactosidase activities and oligosaccharide content in peanuts.
PubMed:Reduction of alpha-galactooligosaccharides in soyamilk by Lactobacillus fermentum CRL 722: in vitro and in vivo evaluation of fermented soyamilk.
PubMed:Antioxidants, low molecular weight carbohydrates, and total antioxidant capacity in strawberries (Fragaria x ananassa): effects of cultivar, ripening, and storage.
PubMed:Growth of Lactobacillus paracasei ssp. paracasei on tofu whey.
PubMed:High-performance capillary electrophoresis with indirect UV detection for determination of alpha-galactosides in Leguminosae and Brassicaceae.
PubMed:Use of carbohydrases in corn-soybean meal-based nursery diets.
PubMed:Synthesis of alpha-galactooligosaccharides with alpha-galactosidase from Lactobacillus reuteri of canine origin.
PubMed:Different food sources affect the gustatory response of Anaphes iole, an egg parasitoid of Lygus Spp.
PubMed:Influence of ozone on cold acclimation in sugar maple seedlings.
PubMed:Soaking the common bean in a domestic preparation reduced the contents of raffinose-type oligosaccharides but did not interfere with nutritive value.
PubMed:Two novel oligosaccharides formed by 1F-fructosyltransferase purified from roots of asparagus (Asparagus officinalis L.).
PubMed:The effect of enzyme treatment of soybean meal on oligosaccharide disappearance and chick growth performance.
PubMed:Effect of soaking, germination, cooking and fermentation on antinutritional factors in cowpeas.
PubMed:Nutritional composition and antinutritional factors of chickpeas (Cicer arietinum L.) undergoing different cooking methods and germination.
PubMed:[The domestic processing of the common bean resulted in a reduction in the phytates and tannins antinutritional factors, in the starch content and in the raffinose, stachiose and verbascose flatulence factors].
PubMed:Indigenous mucuna tempe as functional food.
PubMed:Soy molasses as fermentation substrate for production of butanol using Clostridium beijerinckii BA101.
PubMed:A comparison of nectar- and honeydew sugars with respect to their utilization by the hymenopteran parasitoid Cotesia glomerata.
PubMed:Characteristics and composition of watermelon, pumpkin, and paprika seed oils and flours.
PubMed:Nutritional evaluation of ethanol-extracted lentil flours.
PubMed:Effect of domestic processing on flatus producing factors in ricebean (Vigna umbellata).
PubMed:Effect of soaking process on nutritional quality and protein solubility of some legume seeds.
PubMed:Effect of soaking, cooking and germination on the oligosaccharide content of selected Nigerian legume seeds.
PubMed:Relationships of sweet, bitter, and roasted peanut sensory attributes with carbohydrate components in peanuts.
PubMed:Investigations into genotypic variations of peanut carbohydrates.
PubMed:Transglycosidase activity of Bifidobacterium adolescentis DSM 20083 alpha-galactosidase.
PubMed:Nutrient composition and amino acid pattern of cowpea (Vigna unguiculata (L.) Walp, Fabaceae) grown in the Gizan area of Saudi Arabia.
PubMed:Characterization of Bifidobacterium strains for use in soymilk fermentation.
PubMed:Substrate specificities of Penicillium simplicissimum alpha-galactosidases.
PubMed:Chemical and sensory evaluation of vegetable milks from African yam bean Sphenostylis stenocarpa (Hochst ex A Rich) Harms and maize (Zea mays L.).
PubMed:Effect of processing on flatus producing oligosaccharides in cowpea (Vigna unguiculata) and the tropical African yam bean (Sphenostylis stenocarpa).
PubMed:Effect of different post-harvest treatments on antinutritional factors in seeds of the tribal pulse, Mucuna pruriens (L.) DC.
PubMed:Acceleration of sterol excretion, little meteorism, and less inhibition of iron absorption by Okara Koji, a new foodstuff, in rats.
PubMed:The composition of glyphosate-tolerant soybean seeds is equivalent to that of conventional soybeans.
PubMed:Development by extrusion of soyabari snack sticks: a nutritionally improved soya-maize product based on the Nigerian snack (kokoro).
PubMed:Leguminosae in the diet: the raffinose-stachyose question.
PubMed:Hydrolysis of raffinose and stachyose in cowpea (Vigna unguiculata) flour, using α-galactosidase fromAspergillus niger.
PubMed:Analysis of legume oligosaccharides by high-resolution gas chromatography.
PubMed:Effect of overcooked soybean meal on chicken performance and amino acid availability.
PubMed:Oligosaccharides in several Philippine indigenous food legumes: determination, localization and removal.
PubMed:[Chemical composition of seeds from Cucumeropsis mannii Naudin and their suitability as food].
PubMed:[Effects of soluble carbohydrates from several tropical foods (cassava, peanuts, coconut and papaya) on calcium utilization in the rat].
PubMed:Alpha-galactosidase production and use in a hollow-fiber reactor.
Isol. from soybean meal (Glycine max), tubers of Japanese artichoke (Stachys tubifera) and lentils Stachyose is a tetrasaccharide consisting of two D-galactose units, one D-glucose unit, and one D-fructose unit sequentially linked. Stachyose is a normal human metabolite present in human milk and is naturally found in many vegetables (e.g. green beans, soybeans and other beans) and plants. The glycosylation of serum transferrin from galactosemic patients with a deficiency of galactose-1-phosphate uridyl transferase (EC 2. 7.7 12) is abnormal but becomes normal after treatment with a galactose-free diet. Adhering to a galactose-free diet by strictly avoiding dairy products and known hidden sources of galactose does not completely normalize galactose-1-phosphate (gal-1-P) in erythrocytes from patients with galactosemia, since galactose released from stachyose may be absorbed and contribute to elevated gal-1-P values in erythrocytes of galactosemic patients. (PMID: 7671975, 9499382); Stachyose is a tetrasaccharide consisting of two ?-D-galactose units, one ?-D-glucose unit, and one ?-D-fructose unit sequentially linked as gal(?1?6)gal(?1?6)glc(?1?2?)fru. Stachyose is naturally found in numerous vegetables (e.g. green beans, soybeans and other beans) and plants.
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