| PubMed:[The evaluation of prognostic value of biomarkers in patients with chronic cardiac insufficiency]. |
| PubMed:A Root-Expressed l-Phenylalanine:4-Hydroxyphenylpyruvate Aminotransferase Is Required for Tropane Alkaloid Biosynthesis in Atropa belladonna. |
| PubMed:Tropine forming tropinone reductase gene from Withania somnifera (Ashwagandha): biochemical characteristics of the recombinant enzyme and novel physiological overtones of tissue-wide gene expression patterns. |
| PubMed:Stereo signature molecular descriptor. |
| PubMed:Molecular cloning and catalytic characterization of a recombinant tropine biosynthetic tropinone reductase from Withania coagulans leaf. |
| PubMed:Enhancing the production of tropane alkaloids in transgenic Anisodus acutangulus hairy root cultures by over-expressing tropinone reductase I and hyoscyamine-6β-hydroxylase. |
| PubMed:A general method for palladium-catalyzed direct carbonylation of indole with alcohol and phenol. |
| PubMed:Plant tropane alkaloid biosynthesis evolved independently in the Solanaceae and Erythroxylaceae. |
| PubMed:Development of a liquid chromatography-tandem mass spectrometric method for the simultaneous determination of tropane alkaloids and glycoalkaloids in crops. |
| PubMed:Co-expression of AaPMT and AaTRI effectively enhances the yields of tropane alkaloids in Anisodus acutangulus hairy roots. |
| PubMed:Elucidation of the mechanism of N-demethylation catalyzed by cytochrome P450 monooxygenase is facilitated by exploiting nitrogen-15 heavy isotope effects. |
| PubMed:High-performance liquid-chromatographic tandem-mass spectrometric methods for atropinesterase-mediated enantioselective and chiral determination of R- and S-hyoscyamine in plasma. |
| PubMed:[Datura intoxication--report of three cases]. |
| PubMed:Determination of the natural abundance delta15N of nortropane alkaloids by gas chromatography-isotope ratio mass spectrometry of their ethylcarbamate esters. |
| PubMed:Determination of nitrogen-15 isotope fractionation in tropine: evaluation of extraction protocols for isotope ratio measurement by isotope ratio mass spectrometry. |
| PubMed:Molecular cloning and characterization of two tropinone reductases in Anisodus acutangulus and enhancement of tropane alkaloid production in AaTRI-transformed hairy roots. |
| PubMed:Synthesis of heteroaromatic tropeines and heterogeneous binding to glycine receptors. |
| PubMed:The development of ultrashort acting neuromuscular relaxant tropane derivatives. |
| PubMed:Tropane alkaloids as medicinally useful natural products and their synthetic derivatives as new drugs. |
| PubMed:Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol. |
| PubMed:Characterization of Atropa belladonna L. compounds by capillary electrophoresis-electrospray ionization-time of flight-mass spectrometry and capillary electrophoresis-electrospray ionization-ion trap-mass spectrometry. |
| PubMed:Virtual reality system for planning minimally invasive neurosurgery. Technical note. |
| PubMed:The functional divergence of short-chain dehydrogenases involved in tropinone reduction. |
| PubMed:Synthesis of (nor)tropeine (di)esters and allosteric modulation of glycine receptor binding. |
| PubMed:Calystegines in potatoes with genetically engineered carbohydrate metabolism. |
| PubMed:Differentiation of fibroblastic meningiomas from other benign subtypes using diffusion tensor imaging. |
| PubMed:Optimization of homonuclear 2D NMR for fast quantitative analysis: application to tropine-nortropine mixtures. |
| PubMed:In vitro organogenesis and alkaloid accumulation in Datura innoxia. |
| PubMed:White matter fiber tracking computation based on diffusion tensor imaging for clinical applications. |
| PubMed:Brassicaceae contain nortropane alkaloids. |
| PubMed:Immunolocalisation of two tropinone reductases in potato (Solanum tuberosum L.) root, stolon, and tuber sprouts. |
| PubMed:Quaternary derivatives of granatanol diesters: potent, ultrashort acting non-depolarizing neuromuscular relaxants. |
| PubMed:Tropinone reductases, enzymes at the branch point of tropane alkaloid metabolism. |
| PubMed:Alkaloid content of the seeds from Erythroxylum Coca var. Coca. |
| PubMed:Sensitive and specific liquid chromatographic-tandem mass spectrometric assay for atropine and its eleven metabolites in rat urine. |
| PubMed:Induction of tropane alkaloid formation in transformed root cultures of Brugmansia suaveolens (Solanaceae). |
| PubMed:Overexpression of tropinone reductases alters alkaloid composition in Atropa belladonna root cultures. |
| PubMed:Contribution of diffusion tensor imaging to delineation of gliomas and glioblastomas. |
| PubMed:Antagonist binding in the rat muscarinic receptor A study by docking and X-ray crystallography. |
| PubMed:Altered nitrogen metabolism associated with de-differentiated suspension cultures derived from root cultures of Datura stramonium studied by heteronuclear multiple bond coherence (HMBC) NMR spectroscopy. |
| PubMed:Preparing for chemical terrorism: stability of injectable atropine sulfate. |
| PubMed:Role of 5-HT3 receptors in the mechanisms of central pain syndrome. |
| PubMed:Alkaloids in plants and root cultures of Atropa belladonna overexpressing putrescine N-methyltransferase. |
| PubMed:Structure-activity relationships among derivatives of dicarboxylic acid esters of tropine. |
| PubMed:Receptor binding studies of soft anticholinergic agents. |
| PubMed:Five new nortropane alkaloids and six new amino acids from the fruit of Morus alba LINNE growing in Turkey. |
| PubMed:Calystegines in root cultures of Atropa belladonna respond to sucrose, not to elicitation. |
| PubMed:Photochemical N-demethylation of alkaloids. |
| PubMed:Synthesis, analgesic activity, and binding properties of some epibatidine analogs with a tropine skeleton. |
| PubMed:Biosynthetic studies on the tropane ring system of the tropane alkaloids from Datura stramonium. |
| PubMed:Specificities of the enzymes of N-alkyltropane biosynthesis in Brugmansia and Datura. |
| PubMed:Structures and expression patterns of two tropinone reductase genes from Hyoscyamus niger. |
| PubMed:Cardiovascular response to the injection of acetylcholine into the anterior cingulate region of the medial prefrontal cortex of unanesthetized rats. |
| PubMed:Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis. |
| PubMed:Effect of tropine derivatives, antimuscarinic agents, on the growth of Bombyx mori larvae. |
| PubMed:Atropine Metabolism by Pseudomonas sp. Strain AT3: Evidence for Nortropine as an Intermediate in Tropine Breakdown and Reactions Leading to Succinate. |
| PubMed:Toxicity of field bindweed (Convolvulus arvensis) to mice. |
| PubMed:Phase I and II metabolites of benztropine in rat urine and bile. |
| PubMed:Tropane alkaloids and toxicity of Convolvulus arvensis. |
| PubMed:Tropine dehydrogenase: purification, some properties and an evaluation of its role in the bacterial metabolism of tropine. |
| PubMed:Interference of mandelic acid with the determination of homatropine hydrobromide by second-order derivative spectroscopy. |
| PubMed:The reduction of tropinone in Datura stramonium root cultures by two specific reductases. |
| PubMed:Intrapericardial blocking agents have extracardiac effects in dogs. |
| PubMed:Spontaneous reversal of a tropine induced delirium in organophosphorous compound poisoning. |
| PubMed:Determination of distribution coefficients for some 5-HT3 receptor antagonists by reversed-phase high-performance liquid chromatography. |
| PubMed:Opposite stereospecificity of two tropinone reductases is conferred by the substrate-binding sites. |
| PubMed:Detection and identification of side reactions of halogenated hydrocarbon solvents with amines of pharmaceutical interest by secondary processes to the neutralizations of sulphonphthaleinic dyes with these amines. |
| PubMed:Two tropinone reductases with different stereospecificities are short-chain dehydrogenases evolved from a common ancestor. |
| PubMed:Synthesis and biological activity of a series of aryl tropanyl esters and amides chemically related to 1H-indole-3-carboxylic acid endo 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester. Development of a 5-HT4 agonist endowed with potent antinociceptive activity. |
| PubMed:The isolation and identification of 6-hydroxycyclohepta-1,4-dione as a novel intermediate in the bacterial degradation of atropine. |
| PubMed:Serotonin-induced vasodilatation in the human forearm is mediated by the "nitric oxide-pathway": no evidence for involvement of the 5-HT3-receptor. |
| PubMed:Tropane alkaloid production in Datura stramonium suspension cultures: elicitor and precursor effects. |
| PubMed:Two Tropinone Reductases with Distinct Stereospecificities from Cultured Roots of Hyoscyamus niger. |
| PubMed:Putrescine N-Methyltransferase in Cultured Roots of Hyoscyamus albus: n-Butylamine as a Potent Inhibitor of the Transferase both in Vitro and in Vivo. |
| PubMed:Datura delirium. |
| PubMed:Zatosetron, a potent, selective, and long-acting 5HT3 receptor antagonist: synthesis and structure-activity relationships. |
| PubMed:The formation of 3 alpha- and 3 beta-acetoxytropanes by Datura stramonium transformed root cultures involves two acetyl-CoA-dependent acyltransferases. |
| PubMed:Malonamic acid derivatives as M1 selective muscarinic receptor antagonists. |
| PubMed:Studies on the biosynthesis of tropane alkaloids in Datura stramonium L. transformed root cultures : 1. The kinetics of alkaloid production and the influence of feeding intermediate metabolites. |
| PubMed:Factors regulating tropane-alkaloid production in a transformed root culture of a Datura candida × D. aurea hybrid. |
| PubMed:Atropine- and scopolamine-resistant subtypes of muscarinic receptors in the rabbit aorta. |
| PubMed:Effects of Exogenous Polyamines on Tropane Alkaloid Production by a Root Culture of Duboisia myoporoides. |
| PubMed:[Sites of seizure discharges after intracerebroventricular injection of anisodamine and the antagonism by diazepam in rabbits]. |
| PubMed:Determination of atropine in blood by gas chromatography/mass spectrometry. |
| PubMed:[Effect of several m-cholinoblockaders on the functioning of sodium potential-dependent channels of neuroblastoma cells]. |
| PubMed:Novel 'soft' anticholinergic agents. |
| PubMed:[Studies on the synthesis and neuromuscular-blocking activity of symmetrical bis-and poly-quaternary derivatives of quinuclidine and tropine]. |
| PubMed:Investigation of the Alkaloid Pattern of Datura innoxia Plants by Capillary Gas-Liquid-Chromatography-Mass Spectrometry. |
| PubMed:Metabolism of the tropine indole-3-carboxylate ICS 205-930 by differentiated rat and human hepatoma cells. |
| PubMed:The metabolism of atropine in man. |
| PubMed:Integrated pharmacokinetics and pharmacodynamics of atropine in healthy humans. II: Pharmacodynamics. |
| PubMed:Integrated pharmacokinetics and pharmacodynamics of atropine in healthy humans. I: Pharmacokinetics. |
| PubMed:[Mechanisms of self-regulation and interaction of the central nervous system and of the hypophyseal-sexual system]. |
| PubMed:[Comparative study of the effect of 3 M-cholinergic blockaders on memory and motor activity in rats]. |
| PubMed:Biological activity of the alkaloids of Erythroxylum coca and Erythroxylum novogranatense. |
| PubMed:Axon-myelin transfer of glycerol-labeled lipids and inorganic phosphate during axonal transport. |
| PubMed:Structure-activity requirements for hypotension and alpha-adrenergic receptor blockade by analogues of atropine. |
| PubMed:[Analysis and stability of atropine sulfate and scopolamine hydrobromide. 1. Qualitative detection of alkaloids in the presence of their decomposition products. 73. Contribution to the problem of the use of plastic receptacles for liquid pharmaceuticals]. |
| PubMed:Przewalskia tangutica - A tropane alkaloid-containing plant. |
| PubMed:Partial purification and properties of tropine dehydrogenase from root cultures of Datura stramonium. |
| PubMed:Atropine: a sensitive gas chromatography-mass spectrometry assay and prepharmacokinetic studies. |
| PubMed:The comparative phytochemistry of the genus Erythroxylon. |
| PubMed:Radioimmunoassay for atropine and l-hyoscyamine. |
| PubMed:Some features of modern pharmacology. |
| PubMed:Photaffinity labeling of specific muscarinic antagonist binding sites of brain: I. Preliminary studies using two p-azidophenylacetate esters of tropine. |
| PubMed:Structure-activity relationship in a new series of atropine analogues. 1. N,N'-Disubstituted 6,7-diazabicyclo[3.2.2]nonane derivatives. |
| PubMed:[Antihistaminic and antiserotonin properties of new complex tropine esters]. |
| PubMed:[Effect of cocaine molecule fragments on the central nervous system]. |
| PubMed:C-NMR spectroscopy of tropane alkaloids. |
| PubMed:[Effect of tropaphene and fentolamin on the spasmogenic effects of adrenaline, noradrenaline, serotonin and other biologically active substances]. |
| PubMed:[Scope and limitation of the analytical use of dansyl chloride, II: Formation of secondary dansyl amines by the reaction of dansyl chloride with N-oxides of aliphatic tertiary amino derivatives according to the Polonovski reaction (author's transl)]. |
| PubMed:[Effect of several tropane derivatives on noradrenaline absorption by hypothalamic synaptic vesicles]. |
| PubMed:Tropine derivatives with central activities. Part II: Solvolysis of N-substituted nortropine methanesulfonates. |
| PubMed:Unit-dose assay of tropine alkaloids and their synthetic analogs. |
| PubMed:[Pharmacological properties of some p-chlorophenoxyacetic acid derivatives]. |
| PubMed:Relationships between chemical structure and affinity for postganglionic acetylcholine receptors of the guinea-pig ileum. |
| PubMed:Acetylcholine-like molecular arrangement in psychomimetic anticholinergic drugs. |
| PubMed:[Studies on diphenyl ether derivatives. 3. Synthesis and spasmolytic screening of new quaternary salts of tropine tropates]. |
| PubMed:[Conformation analysis of tropines: conformation of benzoyl tropine and benzoyl-psi-tropine (tropacocaine) and their cholinolytic actions]. |
| PubMed:Studies on carbanilic acid esters of cyclic amino alcohols. 3. Esters of ecgonine, tropine and some related bicyclic alcohols as local anesthetics. |
| PubMed:Blockade of superior cervical ganglionic transmission by tropine-p-tolylacetate and its quaternary methiodide derivative. |
| PubMed:[Comparative pharmacological activity of some esters of tropine, piperidol and oxymethylpyrrolidine]. |
| PubMed:Some derivatives of tropine and pseudotropine. |
| PubMed:[Studies on the extraction of plant constituents. II. Extraction of tropine alkaloid from Scopoliae rhizoma]. |
| PubMed:Synthesis of tropine-labeled atropine. IV. Labeling of the 2, 3, and 4 positions of atropine from citric-14-C acid. |
| PubMed:[Antispasmodic action of tropine alpha-methyl tropate]. |
| PubMed:Pharmacology of new tropine ethers with central activity. |
| PubMed:Synthesis of rropine-labeled atropine 3. Synthesis of N-methyl-14C-tropine and N-methyl-14C-atropine. |
| PubMed:Action of certain tropine esters on voltage-clamped lobster axon. |
| PubMed:Synthesis of tropine-labeled atropine II. Prototype synthesis for the preparation of tropine-14C and atropine-14C from arabinose-14C. |
| PubMed:Spasmolytic and cholinergic blocking properties and toxicity of levomepate, 1-tropine alpha-methyltropate. |
| PubMed:Synthesis of tropine-labeled atropine. I. Micro methods for the synthesis of tropine and for its esterification with tropic acid. |
| PubMed:[Action of tropine alpha methyltropate (levomepate) on bile duct motility in guinea pigs]. |
| PubMed:Tropine 1,2-dithiolane-3-carboxylate, a new alkaloid from Bruguiera sexangula. |
| PubMed:Comparison of the adrenolytic properties of esters formed by tropine and other aminoalcohols with alpha-, beta-diphenylpropionic acid derivatives. |
| PubMed:Potency convergence and crossover in tertiary vs. quaternary tropine amino esters. |
| PubMed:[Contribution to the quantitative paper chromatographic analysis of tropine alkaloids]. |
| PubMed:[A comparison of the adrenolytic properties of esters formed by tropine and other amino alcohols with derivatives of alpha-, beta-diphenylpropionic acid]. |
| PubMed:Some toxic properties of 2-alpha-tropine aryl esters. |
| PubMed:Blockade of excitable nodes of Ranvier by stereoisomeric phenylacetate esters in the tropine and psi-tropine series. 3. |
| PubMed:[THE TRANSFORMATION OF TROPINE INTO PSEUDOTROPINE BY SYNERGISM OF 2 BACTERIAL STRAINS. II]. |
| PubMed:SOME PHARMACOLOGICAL EFFECTS OF N-ALKYL- AND N-ARALKYL-NOR-TROPINE ESTERS. |
| PubMed:INTERACTIONS OF ARYL ESTERS IN THE TROPINE AND PSI-TROPINE SERIES WITH TISSUE CHEMORECEPTORS. THE ORTHO EFFECT. 7. |
| PubMed:COMPARATIVE PHARMACOLOGICAL STUDIES OF GANGLIONIC STIMULANTS: DIMETHYLPHENYLPIPERAZINIUM BROMIDE (DMPP), TETRAMETHYLAMMONIUM BROMIDE (TMA) AND GANGLIONIC STIMULANTS OF THE TROPINE TYPE. I. |
| PubMed:[THE TRANSFORMATION OF TROPINE INTO PSEUDOTROPINE BY THE SYNERGISM OF 2 BACTERIAL STRAINS]. |
| PubMed:STRUCTURE VS. TOXICOLOGIC PARAMETERS IN NEW ESTERS OF TROPINE AND PSI-TROPINE. VI. |
| PubMed:[SEPARATION OF ALKALOIDS BY THIN LAYER CHROMATOGRAPHY. 1. METHODS FOR SEPARATION OF TROPINE ALKALOIDS IN SOLANACEAE DRUGS AND CINCHONA ALKALOIDS]. |
| PubMed:[PHARMACOLOGICAL CHARACTERISTICS OF SOME TROPINE COMPOUNDS]. |
| PubMed:A GAS CHROMATOGRAPHIC DETERMINATION OF PSEUDOTROPINE IN TROPINE. |
| PubMed:COMPARATIVE HYDROLYTIC RATES OF SOME TROPINE ESTERS. |
| PubMed:[DEMONSTRATION OF A CHOLINERGIC FACTOR IN THE TRIGGERING OF OVULATION BY COITUS IN THE RAT. ANTI-OVULAR ACTION OF A TROPINE]. |
| PubMed:[THE EFFECT OF SOME QUATERNARY TROPINE ESTERS ON THE GASTROINTESTINAL SYSTEM]. |
| PubMed:STRUCTURE VS. TOXICITY RELATIONSHIPS IN ARYL ESTERS OF TROPINE AND PSEUDOTROPINE. V. |
| PubMed:[SPATIAL CONFIGURATION AND ACTIVITY OF TROPINE DERIVATIVES]. |
| PubMed:Interference patterns in twitch potentiation of the rat phrenic nerve-diaphragm by aryl esters of tropine and psi-tropine. IV. |
| PubMed:Further elements of structural specificity in potentiation and blockade of excitable tissue preparations by aryl esters of tropine and pseudotropine. III. |
| PubMed:[N-carbobenzyloxy derivatives of nor-tropine and their use in the synthesis of tropeines]. |
| PubMed:Adrenergic neurone blocking tropine derivatives with long-lasting hypotensive action. |
| PubMed:[Determination of atropine, tropine and tropic acid in decomposed atropine solutions]. |
| PubMed:Neuromuscular blocking properties of some bistropinium esters. |
| PubMed:The neuromuscular blocking properties of certain tropine derivatives. |
| PubMed:Further toxicologic properties of aromatic esters in the tropine and psi-tropine series. |
| PubMed:Cholinergic blockade as related to chain length of monoquaternary derivatives of atropine and benzoyl-tropine. |
| PubMed:The neuromuscular blocking properties of a series of bis-quaternary tropeines. |
| PubMed:Pharmacological studies on new tertiary tropine esters. |
| PubMed:Antagonism of the effects of tremorine by tropine derivatives. |
| PubMed:[Synthesis & pharmacology of various tropine & speudotropine esters with substituted pyrrolidine ring]. |
| PubMed:[Inversion by tropine of the cardio-inhibitory action of the vagus]. |
| PubMed:[Adrenalytic characteristics of tropine ethers]. |
| PubMed:[Opsonin and tropine; old and new concepts; personal contributions; their behavior in various diseases]. |
| PubMed:Pharmacologic properties of tropine 4-chlorobenzhydryl ether hydrochloride (SL-6057), a potent long-acting antihistaminic agent. |
| PubMed:[Micromethod of determination of tropine alkaloids in vegetable material]. |
| PubMed:[Treatment of angina pectoris by intrathoracic novocaine and tropine]. |
| PubMed:[Pharmacological properties and clinical effects of the hydrochloride of the benzilic acid ester of tropine]. |
| PubMed:[Pharmacological study on synthetic alkoxy-tropine derivatives]. |
| PubMed:Quaternary derivatives of benzoyltropine and benzoyl-psi-tropine with anticholinergic and local anaesthetic properties. |
| PubMed:Studies on cholinergic blocking substances. 4. Correlation between structure and effect of quaternary derivatives of benzoyltropine and benzoyl psi tropine compounds. |
| PubMed:New anticholinergic drugs in peptic ulcer therapy; preliminary report on tropine benzohydryl (MK-02). |
| PubMed:Treatment of Parkinson's syndrome with tropine benzohydryl ether methane sulfonate and other drugs. |
| PubMed:MK-02 (tropine benzohydryl ether methane sulfonate); a new parasympathetic depressant. |
| PubMed:Effects of prolonged administration of tropine and pilocarpine on the submaxillary gland of the cat. |
| PubMed:The ganglionic blocking action of tropine and tropinium. |
| PubMed:A colorimetric method for the estimation of some tropine alkaloids. |
| PubMed:The action of tropine and heliotridine-alkaloids on excitation, propagation and recovery in muscle. |
3D/inchi