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teflubenzuron
benzamide, N-[[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl]-2,6-difluoro-

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Name:N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide
CAS Number: 83121-18-0Picture of molecule3D/inchi
FDA UNII: FS9P57VL74
Nikkaji Web:J134.962G
Beilstein Number:8229925
MDL:MFCD00068254
XlogP3:4.90 (est)
Molecular Weight:381.11183280
Formula:C14 H6 Cl2 F4 N2 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 222.50 °C. @ 760.00 mm Hg
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): 4.560
Soluble in:
 water, 0.019 mg/L @ 23C (exp)
 water, 0.5109 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Teflubenzuron
Santa Cruz Biotechnology
For experimental / research use only.
Teflubenzuron
Sigma-Aldrich: Sigma
For experimental / research use only.
Teflubenzuron PESTANAL®, analytical standard
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 > 5000 mg/kg
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 18, Pg. S15, 1993.

oral-rat LD50 > 5000 mg/kg
Pesticide Manual. Vol. 9, Pg. 790, 1991.

Dermal Toxicity:
skin-rat LD50 > 2000 mg/kg
Pesticide Manual. Vol. 9, Pg. 790, 1991.

Inhalation Toxicity:
inhalation-rat LC50 > 5038 mg/m3/4H
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 18, Pg. S15, 1993.

 
Safety in Use Information:
Category:
herbicides / pesticides
Recommendation for teflubenzuron usage levels up to:
 not for fragrance use.
 
Recommendation for teflubenzuron flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Reasoned opinion on the review of the existing maximum residue levels (MRLs) for teflubenzuron according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf

Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf

Evaluation of confirmatory data following the Article 12 MRL review for teflubenzuron
View page or View pdf

Setting of import tolerances for teflubenzuron in grapefruits, mandarins and broccoli
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :91734
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide
Chemidplus:0083121180
RTECS:CV3459590 for cas# 83121-18-0
 
References:
 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):91734
Pubchem (sid):135049038
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C18437
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 benzamide, N-[[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl]-2,6-difluoro-
 calicide
 diaract
N-[(3,5-dichlor-2,4-difluorphenyl)carbamoyl]-2,6-difluorbenzamid
1-(3,5-dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl)urea
N-[[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl]-2,6-difluorobenzamide
N-{[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl}(2,6-difluorophenyl)carboxamide
N-{[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl}-2,6-difluorobenzamide
N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide
 nomolt
 teflubenzuron [ISO] [BSI]
 tefluron
 

Articles:

PubMed:Mortality and deformities in European lobster (Homarus gammarus) juveniles exposed to the anti-parasitic drug teflubenzuron.
PubMed:Study on the simultaneous determination of seven benzoylurea pesticides in Oolong tea and their leaching characteristics during infusing process by HPLC-MS/MS.
PubMed:Comparative effects of insecticides with different mechanisms of action on Chrysoperla externa (Neuroptera: Chrysopidae): lethal, sublethal and dose-response effects.
PubMed:Acute toxicity and environmental risk of teflubenzuron to Daphnia magna, Poecilia reticulata and Lemna minor in the absence and presence of sediment.
PubMed:In-situ metathesis reaction combined with ultrasound-assisted ionic liquid dispersive liquid-liquid microextraction method for the determination of phenylurea pesticides in water samples.
PubMed:A broad-spectrum analysis of the effects of teflubenzuron exposure on the biochemical activities and microbial community structure of soil.
PubMed:Determination of 16 insect growth regulators in edible Chinese traditional herbs by liquid chromatography electrospray tandem mass spectrometry.
PubMed:Effects of a methanolic extract of the plant Haplophyllum tuberculatum and of teflubenzuron on female reproduction in the migratory locust, Locusta migratoria (Orthoptera: Oedipodinae).
PubMed:Reshuffling of Aspergillus fumigatus cell wall components chitin and β-glucan under the influence of caspofungin or nikkomycin Z alone or in combination.
PubMed:Control of mushroom sciarid fly Lycoriella ingenua populations with insect growth regulators applied by soil drench.
PubMed:Two-generation effects of the chitin synthesis inhibitor, teflubenzuron, on the aquatic midge Chironomus riparius.
PubMed:Control failure likelihood and spatial dependence of insecticide resistance in the tomato pinworm, Tuta absoluta.
PubMed:[Determination of benzoylurea and bishydrazide pesticide residues in vegetables by ultra performance liquid chromatography-tandem mass spectrometry with matrix solid phase dispersion].
PubMed:The effect of chitin metabolic effectors on the population increase of stored product mites.
PubMed:Side effects of teflubenzuron and chlorfenapyr in Eriopis connexa eggs (Coleoptera: Coccinellidae).
PubMed:Compatibility of Verticillium lecani (Zimm.) with several pesticides.
PubMed:Solid-phase microextraction for the determination of benzoylureas in orange juice using liquid chromatography combined with post-column photochemically induced fluorimetry derivatization and fluorescence detection.
PubMed:Insecticidal resistance and cross-resistance in populations of Cydia pomonella (Lepidoptera: Tortricidae) in central Europe.
PubMed:Determination of benzoylurea insecticide residues in tomatoes by high-performance liquid chromatography with ultraviolet-diode array and atmospheric pressure chemical ionization-mass spectrometry detection.
PubMed:Safe apples for baby-food production: survey of pesticide treatment regimes leaving minimum residues.
PubMed:Multigeneration effects of insect growth regulators on the springtail Folsomia candida.
PubMed:Historical control clinical trial to assess the effectiveness of teflubenzuron for treating sea lice on Atlantic salmon.
PubMed:Randomized clinical trial to investigate the effectiveness of teflubenzuron for treating sea lice on Atlantic salmon.
PubMed:Hazards and uptake of chitin synthesis inhibitors in bumblebees Bombus terrestris.
PubMed:Compatibility of the entomopathogenic fungus Lecanicillium muscarium and insecticides for eradication of sweetpotato whitefly, Bemisia tabaci.
PubMed:Determination of seven benzoylphenylurea insecticides in processed fruit and vegetables using high-performance liquid chromatography/tandem mass spectrometry.
PubMed:Effects of insect growth regulators on the nontarget soil arthropod Folsomia candida (Collembola).
PubMed:Effects of teflubenzuron on sediment processing by members of the Capitella species-complex.
PubMed:Toxicological efficacy of some indigenous dill compounds against the flesh fly, Parasarcophaga dux Thomson.
PubMed:Persistence and residual activity of an organophosphate, pirimiphos-methyl, and three IGRs, hexaflumuron, teflubenzuron and pyriproxyfen, against the cowpea weevil, Callosobruchus maculatus (Coleoptera: Bruchidae).
PubMed:Novaluron (Rimon), a novel IGR: potency and cross-resistance.
PubMed:Influence of a short exposure to teflubenzuron residues on the predation of thrips by Iphiseius degenerans (Acari: Phytoseiidae) and Orius laevigatus (Hemiptera: Anthocoridae).
PubMed:Determination of seventeen polar/thermolabile pesticides in apples and apricots by liquid chromatography/mass spectrometry.
PubMed:Clinical efficacy of teflubenzuron (Calicide) for the treatment of Lepeophtheirus salmonis infestations of farmed Atlantic salmon Salmo salar at low water temperatures.
PubMed:Age-dependent response to insecticides and enzymatic variation in susceptible and resistant codling moth larvae.
PubMed:Field trials in Norway with SLICE (0.2% emamectin benzoate) for the oral treatment of sea lice infestation in farmed Atlantic salmon Salmo salar.
PubMed:New developments in insecticide resistance in the glasshouse whitefly (Trialeurodes vaporariorum) and the two-spotted spider mite (Tetranychus urticae) in the UK.
PubMed:Transformation of the insecticide teflubenzuron by microorganisms.
PubMed:Dissipation of teflubenzuron and triflumuron residues in field-sprayed and cold-stored pears.
PubMed:Evaluation of teflubenzuron residue levels in grapes exposed to field treatments and in the must and wine produced from them.
PubMed:High-performance liquid chromatographic determination of benzoylurea insecticides residues in grapes and wine using liquid and solid-phase extraction.
PubMed:Liquid chromatographic determination of five benzoylurea insecticides in fruit and vegetables.
PubMed:Metabolism of the insecticide teflubenzuron in rats.
PubMed:[First drafts of the Environmental Health Criteria (EHC) circulated for comments by IPCS in 1995-1996].
PubMed:Effects of some insect growth regulators on growth of Aspergillus flavus and its productivity of aflatoxin B1 and lipids.
PubMed:[The action of insect developmental regulators on the housedust mites Dermatophagoides pteronyssinus (Trouessart, 1897) and D. farinae Hughes, 1961 (Acari: Pyroglyphidae)].
PubMed:[Small-scale evaluation of the efficacy of growth-regulating insecticides on larvae of the Simulium damnosum complex (Diptera: Simuliidae)].
PubMed:Ecdysteroid-stimulated synthesis and secretion of an N-acetyl-D-glucosamine-rich glycopeptide in a lepidopteran cell line derived from imaginal discs.
PubMed:Evaluation of the control of mosquitoes with insect growth regulators.
PubMed:Efficacy of new insect growth regulators against mosquito larvae in dairy wastewater lagoons.
PubMed:Efficacy of CME 134 against mosquitoes (Diptera: Culicidae): effects on nontarget organisms and evaluation of potential chemical persistence.
PubMed:Laboratory & field evaluation of three insect growth regulators against mosquito vectors.
PubMed:New ways how to control development of the house fly larvae (Musca domestica) in litter.
 
Notes:
effective against development of house fly larvae (musca domestica).
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