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formamidine
methanoic acid amidine

Supplier Sponsors

CAS Number: 463-52-5Picture of molecule3D/inchi
FDA UNII: M8KP3Q82AG
Nikkaji Web:J231.841E
Beilstein Number:878149
MDL:MFCD11501605
XlogP3-AA:-0.80 (est)
Molecular Weight:44.05688000
Formula:C H4 N2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 81.00 °C. @ 760.00 mm Hg
Boiling Point: 46.30 °C. @ 760.00 mm Hg (est)
Vapor Pressure:337.200000 mmHg @ 25.00 °C. (est)
Flash Point: -1.00 °F. TCC ( -18.20 °C. ) (est)
logP (o/w): -1.170 (est)
Soluble in:
 water, 6.671e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
formamidine
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
herbicides / pesticides
Recommendation for formamidine usage levels up to:
 not for fragrance use.
 
Recommendation for formamidine flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Reasoned Opinion on the modification of the existing MRL for formetanate in strawberries
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EPI System: View
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Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :68047
National Institute of Allergy and Infectious Diseases:Data
methanimidamide
Chemidplus:0000463525
 
References:
 methanimidamide
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):68047
Pubchem (sid):135025674
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 formamidinium
 formimidamide
 imidoformamide
 methanimidamide
 methanoic acid amidine
 

Articles:

PubMed:pH oscillations and mechanistic analysis in the hydrogen peroxide-sulfite-thiourea reaction system.
PubMed:Cerium(III/IV) formamidinate chemistry, and a stable cerium(IV) diolate.
PubMed:Probing the limits of ligand steric bulk: backbone C-H activation in a saturated N-heterocyclic carbene.
PubMed:Topical treatment with probiotic Lactobacillus brevis CD2 inhibits experimental periodontal inflammation and bone loss.
PubMed:Concerted halogen bonding and orthogonal metal-halogen interactions in dimers of lithium formamidinate and halogenated formamidines: an ab initio study.
PubMed:New azido-substituted tantalum compounds: syntheses and DFT examination of nitrogen-rich mono-, di-, and trinuclear tantalum(V) compounds.
PubMed:Acaricide and ivermectin resistance in a field population of Rhipicephalus microplus (Acari: Ixodidae) collected from red deer (Cervus elaphus) in the Mexican tropics.
PubMed:The protective effect of HET0016 on brain edema and blood-brain barrier dysfunction after cerebral ischemia/reperfusion.
PubMed:In vitro induction of apoptosis and necrosis by new derivatives of daunorubicin.
PubMed:Amitraz.
PubMed:Competition between hydrogen bonds and halogen bonds in complexes of formamidine and hypohalous acids.
PubMed:In vitro and in vivo evaluation of cypermethrin, amitraz, and piperonyl butoxide mixtures for the control of resistant Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) in the Mexican tropics.
PubMed:Synthesis, structure, and reactivity of lanthanide complexes incorporating indolyl ligands in novel hapticities.
PubMed:20-Hydroxyeicosatetraenoic acid inhibition attenuates balloon injury-induced neointima formation and vascular remodeling in rat carotid arteries.
PubMed:Increased 20-HETE synthesis explains reduced cerebral blood flow but not impaired neurovascular coupling after cortical spreading depression in rat cerebral cortex.
PubMed:Evaluation of the DNA damaging effects of amitraz on human lymphocytes in the Comet assay.
PubMed:Selective oxidation of thiourea with H(2)O(2) catalyzed by [Ru(III)(edta)(H(2)O)](-): kinetic and mechanistic studies.
PubMed:Synergistic actions of formamidine insecticides on the activity of pyrethroids and neonicotinoids against Aedes aegypti (Diptera: Culicidae).
PubMed:Unique stepwise substitution reaction of a mono(guanidinate)tetraplatinum complex with amidines, giving mono(amidinate)tetraplatinum complexes through mixed-ligand intermediate complexes.
PubMed:Synthesis, structures and reactivity of lanthanoid(II) formamidinates of varying steric bulk.
PubMed:Treatment with the cytochrome P450 ω-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats.
PubMed:Molecular cloning and pharmacological characterisation of a tyramine receptor from the rice stem borer, Chilo suppressalis (Walker).
PubMed:Thermal fluctuations and infrared spectra of the formamide-formamidine complex.
PubMed:Synthesis of biologically active and photostable rigid poly(vinyl chloride).
PubMed:20-HETE induces hyperglycemia through the cAMP/PKA-PhK-GP pathway.
PubMed:Chronic doxorubicin cardiotoxicity modulates cardiac cytochrome P450-mediated arachidonic acid metabolism in rats.
PubMed:Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer.
PubMed:Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases.
PubMed:Amitraz poisoning.
PubMed:Inhibitors of 20-hydroxyeicosatetraenoic acid (20-HETE) formation attenuate the natriuretic effect of dopamine.
PubMed:Nitrogen incorporation in CH(4)-N(2) photochemical aerosol produced by far ultraviolet irradiation.
PubMed:Sodium chloride concentration affects yield, quality, and sensory acceptability of vacuum-tumbled marinated broiler breast fillets.
PubMed:Protective effect of 20-hydroxyeicosatetraenoic acid (20-HETE) on adriamycin-induced toxicity of human renal tubular epithelial cell (HK-2).
PubMed:Assessment of the adverse effects of the acaricide amitraz: in vitro evaluation of genotoxicity.
PubMed:Attenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitor.
PubMed:Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures.
PubMed:Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1 subtype.
PubMed:Direct condensation of sulfonamide and formamide: NaI-catalyzed synthesis of N-sulfonyl formamidine using TBHP as oxidant.
PubMed:1,5,2,4,6,8-Dithiatetrazocine. Synthesis, computation, crystallography and voltammetry of the parent heterocycle.
PubMed:Bioactivation of 4-Ipomeanol by a CYP4B enzyme in bovine lung and inhibition by HET0016.
PubMed:Alkoxyamine-derived formamidines: configurational control and molecular folding.
PubMed:Redetermination of (E)-N,N'-bis-(4-bromo-phen-yl)formamidine.
PubMed:A new in vitro test to evaluate the resistance level against acaricides of the cattle tick, Rhipicephalus (Boophilus) microplus.
PubMed:Inhibition of 20-HETE attenuates diabetes-induced decreases in retinal hemodynamics.
PubMed:Modeling energy landscapes of proton motion in nonaqueous, tethered proton wires.
PubMed:The cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid system: a regulator of endothelial precursor cells derived from human umbilical cord blood.
PubMed:Microwave-assisted synthesis of a pyrazolyl ketone library for evaluation as p38 MAPK inhibitors in Werner syndrome cells.
PubMed:Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats.
PubMed:Amine exchange in formamidines: an experimental and theoretical study.
PubMed:20-Hydroxyeicosatetraenoic acid induces apoptosis in neonatal rat cardiomyocytes through mitochondrial-dependent pathways.
PubMed:Synergy between fipronil and amitraz in a Rhipicephalus sanguineus tick residual contact test.
PubMed:20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II and endothelin-1.
PubMed:Synthesis and crystal structure of a rare square-planar Co(II) complex of a hydroxyamidinate ligand.
PubMed:Synthesis, X-ray crystallography characterization, vibrational spectroscopic, molecular electrostatic potential maps, thermodynamic properties studies of N,N'-di(p-thiazole)formamidine.
PubMed:Selectivity of externally facing ion-binding sites in the Na/K pump to alkali metals and organic cations.
PubMed:CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent.
PubMed:Role of 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of vascular function in a model of hypertension and endothelial dysfunction.
PubMed:X-ray crystallography characterization, vibrational spectroscopy, NMR spectra and quantum chemical DFT/HF study of N,N'-di(2-methoxyphenyl)formamidine.
PubMed:Discovery and characterization of an amidinotransferase involved in the modification of archaeal tRNA.
PubMed:Double-stranded supramolecular assembly through salt bridge formation between rigid and flexible amidine and carboxylic acid strands.
PubMed:A computational study of the nuclear magnetic resonance parameters for double proton exchange pathways in the formamide-formic acid and formamide-formamidine complexes.
PubMed:The role of 20-hydroxyeicosatetraenoic acid in cerebral arteriolar constriction and the inhibitory effect of propofol.
PubMed:Pharmacological characterization of a Bombyx mori alpha-adrenergic-like octopamine receptor stably expressed in a mammalian cell line.
PubMed:Stereochemical and conformational exchanges in N,N'-di(2-pyridyl)formamidines: An X-ray and (1)H NMR study.
PubMed:Down-regulation of 20-HETE synthesis and signaling inhibits renal adenocarcinoma cell proliferation and tumor growth.
PubMed:Design, synthesis and pharmacological evaluation of a series of 5-carbethoxy-4-chloro-6-(substituted amino)pyrimidines as potential analgesic and anti-flammatory agents with very low ulcerogenic potential.
PubMed:Expression and characterization of CYP4V2 as a fatty acid omega-hydroxylase.
PubMed:Imidazol-2-ylidene-4-olate: an anionic N-heterocyclic carbene pre-programmed for further derivatization.
PubMed:The role of 20-hydroxyeicosatetraenoic acid in adrenocorticotrophic hormone and dexamethasone-induced hypertension.
PubMed:Cytotoxicity and cellular uptake of doxorubicin and its formamidine derivatives in HL60 sensitive and HL60/MX2 resistant cells.
PubMed:Kidney androgen-regulated protein transgenic mice show hypertension and renal alterations mediated by oxidative stress.
PubMed:Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury.
PubMed:Role of 20-hydroxyeicosatetraenoic acid in altering vascular reactivity in diabetes.
PubMed:Endothelin rather than 20-HETE contributes to loss of pial arteriolar dilation during focal cerebral ischemia with and without polymeric hemoglobin transfusion.
PubMed:Cytotoxicity and inhibitory properties against topoisomerase II of doxorubicin and its formamidine derivatives.
PubMed:Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.
PubMed:Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD.
PubMed:N,N-Bis(6-methyl-2-pyrid-yl)formamidine.
PubMed:N-Ethyl-N-phenyl-N'-tosyl-formamidine.
PubMed:N,N-Bis(2-pyrid-yl)formamidine.
PubMed:N,N-Bis-(2,6-di-methyl-phen-yl)-N-hydroxyformamidine N,N'-bis-(2,6-dimethyl-phen-yl)-N-oxidoformamidinium dichloro-methane solvate.
PubMed:Theoretical studies on the water-assisted hydrolysis of N,N-dimethyl-N'-(2',3'-dideoxy-3'-thiacytidine) formamidine with three water molecules.
PubMed:Parallel synthesis of trisubstituted formamidines: a facile and versatile procedure.
PubMed:Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury.
PubMed:Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats.
PubMed:The use of formamidine protection for the derivatization of aminobenzoic acids.
PubMed:Role of CYP epoxygenases in A2A AR-mediated relaxation using A2A AR-null and wild-type mice.
PubMed:Cytochrome P450 omega-hydroxylase inhibition reduces cardiomyocyte apoptosis via activation of ERK1/2 signaling in rat myocardial ischemia-reperfusion.
PubMed:Intravenous formulation of N-hydroxy-N'-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for inhibition of rat brain 20-hydroxyeicosatetraenoic acid formation.
PubMed:A stable anionic N-heterocyclic carbene and its zwitterionic complexes.
PubMed:Rapid and sensitive ultra-high-pressure liquid chromatography-quadrupole time-of-flight mass spectrometry for the quantification of amitraz and identification of its degradation products in fruits.
PubMed:20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease.
PubMed:Toward more efficient CCSD(T) calculations of intermolecular interactions in model hydrogen-bonded and stacked dimers.
PubMed:Expression of CYP4A1 in U251 human glioma cell induces hyperproliferative phenotype in vitro and rapidly growing tumors in vivo.
PubMed:Interaction of nitric oxide, 20-HETE, and EETs during functional hyperemia in whisker barrel cortex.
PubMed:A facile preparation of imidazolinium chlorides.
PubMed:Syntheses, structures and magnetism of linear tri- and tetra-copper chains containing anions of N,N'-bis(pyrimidine-2-yl)formamidine.
PubMed:20-HETE increases renal sympathetic nerve activity via activation of chemically and mechanically sensitive muscle afferents.
PubMed:Modulation of serum concentrations and hepatic metabolism of 17beta-estradiol and testosterone by amitraz in rats.
PubMed:A monoclinic polymorph of N,N'-bis-(2,6-diisopropyl-phen-yl)formamidine.
PubMed:Theoretical study on the hydrolysis mechanism of N,N-dimethyl-N'-(2-oxo-1, 2-dihydro-pyrimidinyl)formamidine: water-assisted mechanism and cluster-continuum model.
PubMed:Hoogsteen vs. Watson-Crick base pairing: incorporation of 2-substituted adenine- and 7-deazaadenine 2'-deoxy-beta-D-ribonucleosides into oligonucleotides.
PubMed:Synthesis of DNA-oligonucleotides damaged by arylamine-modified 2'-deoxyguanosine.
PubMed:Facile synthesis of optically active imidazole derivatives.
PubMed:Role of cytochrome P450 metabolites of arachidonic acid in regulation of corporal smooth muscle tone in diabetic and older rats.
PubMed:Effect of acaricides on the activity of glutathione transferases from the parasitic mite Sarcoptes scabiei.
PubMed:Steric modulation of coordination number and reactivity in the synthesis of lanthanoid(III) formamidinates.
PubMed:Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine.
PubMed:NMR studies of double proton transfer in hydrogen bonded cyclic N,N'-diarylformamidine dimers: conformational control, kinetic HH/HD/DD isotope effects and tunneling.
PubMed:Crystal structures and solution behaviors of dinuclear d(10)-metal complexes containing anions of N,N'-bis(pyrimidine-2-yl)formamidine.
PubMed:Adenine synthesis in interstellar space: mechanisms of prebiotic pyrimidine-ring formation of monocyclic HCN-pentamers.
PubMed:A study on immunotoxicological effects of subacute amitraz exposure in rats.
PubMed:Relative stability of formamidine and carbamate groups in the bifunctional pesticide formetanate hydrochloride.
PubMed:Vascular cytochrome P450 4A expression and 20-hydroxyeicosatetraenoic acid synthesis contribute to endothelial dysfunction in androgen-induced hypertension.
PubMed:Role of endogenous CYP450 metabolites of arachidonic acid in maintaining the glomerular protein permeability barrier.
PubMed:Biological properties of new derivatives of daunorubicin.
PubMed:Long-term fenofibrate treatment impairs endothelium-dependent dilation to acetylcholine by altering the cyclooxygenase pathway.
PubMed:Cytochrome P-450 monooxygenases in control of renal haemodynamics and arterial pressure in anaesthetized rats.
PubMed:Elevations in renal interstitial hydrostatic pressure and 20-hydroxyeicosatetraenoic acid contribute to pressure natriuresis.
PubMed:Identification of pesticide transformation products in food by liquid chromatography/time-of-flight mass spectrometry via "fragmentation-degradation" relationships.
PubMed:Synthesis and biological evaluation of some 5-ethoxycarbonyl-6-isopropylamino-4-(substitutedphenyl)aminopyrimidines as potent analgesic and anti-inflammatory agents.
PubMed:Canine renal cortical necrosis and haemorrhage following ingestion of an Amitraz-formulated insecticide dip.
PubMed:CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime].
PubMed:Nitric oxide/cytochrome P450 interactions in cyclosporin A-induced effects in the rat.
PubMed:Synthesis and structural characterisation of heavy alkaline earth N,N'-bis(aryl)formamidinate complexes.
PubMed:VEGF-induced relaxation of pulmonary arteries is mediated by endothelial cytochrome P-450 hydroxylase.
PubMed:Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE.
PubMed:Comparison of the reproductive biology between acaricide-resistant and acaricide-susceptible Rhipicephalus (Boophilus) microplus (Acari: Ixodidae).
PubMed:Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia.
PubMed:An efficient synthesis of acyclic N7- and N9-adenine nucleosides via alkylation with secondary carbon electrophiles to introduce versatile functional groups at the C-1 position of acyclic moiety.
PubMed:Glial cells dilate and constrict blood vessels: a mechanism of neurovascular coupling.
PubMed:Acute amitraz poisoning in adults: clinical features, laboratory findings, and management.
PubMed:9L gliosarcoma cell proliferation and tumor growth in rats are suppressed by N-hydroxy-N'-(4-butyl-2-methylphenol) formamidine (HET0016), a selective inhibitor of CYP4A.
PubMed:Synthesis and in solution and solid state structural study of intramolecular Pt...H interactions in pentafluorophenyl platinum(II) complexes containing the ligands triazene, formamidine, and 2-aminopyridine.
PubMed:Amitraz: an unusual aetiology of Ogilvie's syndrome.
PubMed:Taking the 20-HETE out of the cardiovascular system: the potential of 20-HETE synthesis inhibitors.
PubMed:Cytochrome P450 4A isoform inhibitory profile of N-hydroxy-N'-(4-butyl-2-methylphenyl)-formamidine (HET0016), a selective inhibitor of 20-HETE synthesis.
PubMed:Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A.
PubMed:Stable planar six-pi-electron six-membered N-heterocyclic carbenes with tunable electronic properties.
PubMed:Inhibition of Ca2+/calmodulin-dependent protein kinase II, RAS-GTPase and 20-hydroxyeicosatetraenoic acid attenuates the development of diabetes-induced vascular dysfunction in the rat carotid artery.
PubMed:Elevated plasma cysteinylglycine levels caused by cilastatin-associated antibiotic treatment.
PubMed:Structural and magnetic evidence concerning spin crossover in formamidinate compounds with ru2 5+ cores.
PubMed:Steric engineering of C-F activation with lanthanoid formamidinates.
PubMed:A theoretical study on the mechanism of the reductive half-reaction of xanthine oxidase.
PubMed:Linear and cyclic tetranuclear copper(I) complexes containing anions of N,N'-bis(pyrimidine-2-yl)formamidine.
PubMed:Inhibitors of cytochrome P450 4A suppress angiogenic responses.
PubMed:Paramagnetic precursors for supramolecular assemblies: selective syntheses, crystal structures, and electrochemical and magnetic properties of Ru2(O2CMe)4-n(formamidinate)nCl complexes, n = 1-4.
PubMed:An in vitro larval immersion microassay for identifying and characterizing candidate acaricides.
PubMed:Interactions of novel morpholine and hexamethylene derivatives of anthracycline antibiotics with DNA.
PubMed:Modular synthesis of formamidines and their formation of stable organogels.
PubMed:Reaction products of W(CO)(6) with formamidines; electronic structure of a W(2)(mu-CO)(2) core with unsymmetric bridging carbonyls.
PubMed:Effects of amitraz on cytochrome P450-dependent monooxygenases and estrogenic activity in MCF-7 human breast cancer cells and immature female rats.
PubMed:[Control strategies against Varroa mites].
PubMed:Amitraz poisoning: clinical and laboratory findings.
PubMed:Experimental and theoretical evidence of basic site preference in polyfunctional superbasic amidinazine: N(1),N(1)-dimethyl-N(2)-beta-(2-pyridylethyl)formamidine.
PubMed:Detection and characterization of amitraz resistance in the southern cattle tick, Boophilus microplus (Acari: Ixodidae).
PubMed:Potent nonclassical nucleoside antiviral drugs based on the N,N-diarylformamidine concept.
PubMed:Expanded chemistry of formamidine ureas.
PubMed:Formamidine ureas as tunable electrophiles.
PubMed:Smooth muscle--specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels.
PubMed:Molecular squares with paramagnetic diruthenium corners: synthetic and crystallographic challenges.
PubMed:Inhibitors of 20-HETE formation promote salt-sensitive hypertension in rats.
PubMed:First practical synthesis of formamidine ureas and derivatives.
PubMed:Report of eight children with amitraz intoxication.
PubMed:Contribution of 5-hydroxytryptamine1B receptors and 20-hydroxyeiscosatetraenoic acid to fall in cerebral blood flow after subarachnoid hemorrhage.
PubMed:Contributions of 20-HETE to the antihypertensive effects of Tempol in Dahl salt-sensitive rats.
PubMed:Structural studies of N,N'-di(ortho-fluorophenyl)formamidine group 1 metallation.
PubMed:CYP4A metabolites of arachidonic acid and VEGF are mediators of skeletal muscle angiogenesis.
PubMed:NMR studies of the tautomerism of cyclo-tris(4-R-2,6-pyridylformamidine) in solution and in the solid state.
PubMed:Comparative toxic and genotoxic effects of chloroacetanilides, formamidines and their degradation products on Vibrio fischeri and Chironomus riparius.
PubMed:Synthesis of 99mTc-ciprofloxacin by different methods and its biodistribution.
PubMed:Basic toxicological approach has been effective in two poisoned patients with amitraz ingestion: case reports.
PubMed:20-HETE contributes to the acute fall in cerebral blood flow after subarachnoid hemorrhage in the rat.
PubMed:[Effects of occupational exposure to formamidines on cardiovascular functions].
PubMed:Discovery of a N'-hydroxyphenylformamidine derivative HET0016 as a potent and selective 20-HETE synthase inhibitor.
PubMed:Quadruply Bonded Dichromium Complexes with Variously Fluorinated Formamidinate Ligands.
PubMed:"One-pot" synthesis and antimalarial activity of formamidine derivatives of 4-anilinoquinoline.
PubMed:Role of guanylyl cyclase and cytochrome P-450 on renal response to nitric oxide.
PubMed:Minimal amidine structure for inhibition of nitric oxide biosynthesis.
PubMed:HET0016, a potent and selective inhibitor of 20-HETE synthesizing enzyme.
PubMed:Proton motion and proton transfer in the formamidine-formic acid complex: an Ab initio projector augmented wave molecular dynamics study.
PubMed:Interaction of formamidine pesticides with the presynaptic alpha(2)-adrenoceptor regulating.
PubMed:Dinuclear and heteropolynuclear complexes containing Mo2(4+) units.
PubMed:Tyramine injections reduce locust viability.
PubMed:The ability of new formamidine sugar-modified derivatives of daunorubicin to stimulate free radical formation in three enzymatic systems: NADH dehydrogenase, NADPH cytochrome P450 reductase and xanthine oxidase.
PubMed:Susceptibility to two pyrethroids in Boophilus microplus (Acari: Ixodidae) populations of northwest Argentina. Preliminary results.
PubMed:Effects of the pesticide amitraz and its metabolite BTS 27271 on insulin and glucagon secretion from the perfused rat pancreas: involvement of alpha2D-adrenergic receptors.
PubMed:In vitro and in vivo effects of formamidines in locust (Locusta migratoria migratorioides).
PubMed:Lorentzian noise in single gramicidin A channel formamidinium currents.
PubMed:Isolation of a cDNA for an octopamine-like, G-protein coupled receptor from the cattle tick, Boophilus microplus.
PubMed:Neuroendocrine and reproductive effects of contemporary-use pesticides.
PubMed:S-oxygenation of thiourea results in the formation of genotoxic products.
PubMed:The effect of biogenic amines and their analogs on carbohydrate metabolism in the fat body of the cockroach Blaberus discoidalis.
PubMed:An unusual poisoning with the unusual pesticide amitraz.
PubMed:Molecular dynamics study of free energy profiles for organic cations in gramicidin A channels.
PubMed:Synthesis and assessment of formamidines as new histamine H2-receptor antagonists.
PubMed:Novel histamine H3 receptor antagonists: synthesis and evaluation of formamidine and S-methylisothiourea derivatives.
PubMed:Synergism of toxicity of N,N-diethyl-m-toluamide to German cockroaches (Orthoptera: Blattellidae) by hydrolytic enzyme inhibitors.
PubMed:Evaluation of C-(beta-D-galactosyl) and C-(2-deoxy-D-lyxo-hex-1-enopyranosyl) (D-galactal type) derivatives as inhibitors of beta-D-galactosidase from Escherichia coli.
PubMed:Novel Bicyclic Lactams as XaaPro Type VI beta Turn Mimics: Design, Synthesis, and Evaluation.
PubMed:Total Synthesis of (-)-Tetrahydropalmatine via Chiral Formamidine Carbanions: Unexpected Behavior with Certain Ortho-Substituted Electrophiles.
PubMed:Synthesis and Structural Studies of Platinum Complexes Containing Monodentate, Bridging, and Chelating Formamidine Ligands.
PubMed:The permeation of organic cations through cAMP-gated channels in mammalian olfactory receptor neurons.
PubMed:Gramicidin tryptophans mediate formamidinium-induced channel stabilization.
PubMed:Inhibition of insulin release by a formamidine pesticide amitraz and its metabolites in a rat beta-cell line: an action mediated by alpha-2 adrenoceptors, a GTP-binding protein and a decrease in cyclic AMP.
PubMed:Influence of the formamidine pesticide amitraz and its metabolites on porcine myometrial contractility: involvement of alpha 2-adrenoceptors and Ca2+ channels.
PubMed:Monovalent amidiniums block calcium channels in chick sensory neurons.
PubMed:Antinociceptive effect of amitraz in mice and rats.
PubMed:N4-(dialkylamino)methylene derivatives of 2'-deoxycytidine and arabinocytidine: physicochemical studies for potential prodrug applications.
PubMed:Properties of an arylalkylamine N-acetyltransferase from the nematode, Ascaridia galli.
PubMed:Formamidinium-induced dimer stabilization and flicker block behavior in homo- and heterodimer channels formed by gramicidin A and N-acetyl gramicidin A.
PubMed:Amides and formamidines with antinociceptive activity (note II).
PubMed:Amides and formamidines with antinociceptive activity (note I).
PubMed:Influence of the formamidine pesticide chlordimeform on ovulation in the female hamster: dissociable shifts in the luteinizing hormone surge and oocyte release.
PubMed:Effects of amitraz on motor function.
PubMed:The permeation properties of small organic cations in gramicidin A channels.
PubMed:Calcium entry blockade as a mechanism for chlordimeform-induced inhibition of motor activity in the isolated guinea-pig ileum.
PubMed:Gramicidin channel selectivity. Molecular mechanics calculations for formamidinium, guanidinium, and acetamidinium.
PubMed:Comet Halley as an aggregate of interstellar dust and further evidence for the photochemical formation of organics in the interstellar medium.
PubMed:Sublethal effects of the formamidine amitraz on honeybees gut lipids, following in vivo injections.
PubMed:Estimation of flavin-containing monooxygenase activities in crude tissue preparations by thiourea-dependent oxidation of thiocholine.
PubMed:The formamidine pesticides chlordimeform and amitraz decrease hepatic glutathione in mice through an interaction with alpha 2-adrenoceptors.
PubMed:Adenine photodimerization in deoxyadenylate sequences: elucidation of the mechanism through structural studies of a major d(ApA) photoproduct.
PubMed:Substituent effect on the stereochemistry of H2-receptor antagonists of the phenylformamidine series. A conformation-dependent mode of interaction with the H2 receptor.
PubMed:Rat strain and stock comparisons using a functional observational battery: baseline values and effects of amitraz.
PubMed:Interaction between amitraz and alpha 2-adrenoceptors inhibits epinephrine-induced canine platelet aggregation.
PubMed:Quantification of imipenem's primary metabolite in plasma by postcolumn chemical rearrangement and UV detection.
PubMed:Synthesis and biological activity of the 2-desamino and 2-desamino-2-methyl analogues of aminopterin and methotrexate.
PubMed:Formamidines as synergists of cypermethrin in susceptible and pyrethroid resistant house flies (Diptera: Muscidae).
PubMed:Prebiotic synthesis of histidine.
PubMed:Synthesis and biological evaluation of new antimuscarinic compounds with amidine basic centers. A useful bioisosteric replacement of classical cationic heads.
PubMed:Hexocyclium derivatives with a high selectivity for smooth muscle muscarinic receptors.
PubMed:[Production and antineoplastic activity of new asymmetric azines on the rubomycin base].
PubMed:Irreversible H2-antagonism of the four isomeric butyl analogues of mifentidine.
PubMed:[The effect of pesticides-CDM and AMZ on inhibition of the binding of 3H-clonidine to alpha 2-adrenoreceptor in rat forebrain tissue].
PubMed:Central and peripheral alpha-adrenoceptor actions of amitraz in the dog.
PubMed:Synthesis and structure-activity relationship of C5-substituted analogues of (+-)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine [(+-)-desmethyl-MK801]: ligands for the NMDA receptor-coupled phencyclidine binding site.
PubMed:Octopamine uptake and metabolism in the insect nervous system.
PubMed:Synthesis of 11C-labeled (+-)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imin e [(+-)-[11C]MK801].
PubMed:Amitraz-induced glucose intolerance in rats: antagonism by yohimbine but not by prazosin.
PubMed:Formamidine pesticides and alpha 2-adrenoceptors: studies with amitraz and chlordimeform in rats and development of a radioreceptor binding assay.
PubMed:The formamidine amitraz as a hyperglycemic alpha-agonist in worker honeybees (Apis mellifera mellifera L.) in vivo.
PubMed:N-(fluoroethyl)(imidazolylphenyl)formamidines. The issue of the active species of mifentidine.
PubMed:Acute and chronic effects of the pesticide amitraz on alpha 2-adrenoceptors in mouse brain.
PubMed:Investigations of amitraz neurotoxicity in rats. III. Effects on motor activity and inhibition of monoamine oxidase.
PubMed:Technetium-99m spiperone dithiocarbamate: a potential radiopharmaceutical for dopamine receptor imaging with SPECT.
PubMed:Enhanced susceptibility to kindling by chlordimeform may be mediated by a local anesthetic action.
PubMed:Comparison of chlordimeform and carbaryl using a functional observational battery.
PubMed:Permeability to various cations of the voltage-dependent sodium channel of isolated rat hippocampal pyramidal neurons.
PubMed:Increased hippocampal excitability produced by amitraz.
PubMed:Formamidine pesticides enhance susceptibility to kindled seizures in amygdala and hippocampus of the rat.
PubMed:Alpha 2-adrenoceptors as a target for formamidine pesticides: in vitro and in vivo studies in mice.
PubMed:Effects of topical application of amitraz on plasma glucose and insulin concentrations in dogs.
PubMed:The toxicity of disulphides to isolated hepatocytes and mitochondria.
PubMed:The bradycardic and mydriatic effects of chlordimeform and its demethylated analogs in the rat: antagonism by idazoxan but not by prazosin.
PubMed:Characterization of nonheme iron and reaction mechanism of bromoperoxidase in Corallina pilulifera.
PubMed:Investigations of amitraz neurotoxicity in rats. I. Effects on operant performance.
PubMed:Investigations of amitraz neurotoxicity in rats. II. Effects on visual evoked potentials.
PubMed:Cardiovascular and respiratory effects of the acaricide amitraz.
PubMed:Further evidence to support the alpha 2-adrenergic nature of amitraz-induced decrease in intestinal motility.
PubMed:Interaction of the pesticide chlordimeform with adrenergic receptors in mouse brain: an in vitro study.
PubMed:Cholinergic involvement in the action of formetanate on operant behavior in rats.
PubMed:Mechanism of ammonium translocation in rat liver mitochondria. Finger-printing of the translocator.
PubMed:Prebiotic synthesis of imidazole-4-acetaldehyde and histidine.
PubMed:Technetium-99m diethyldithiocarbamate (DDC): comparison with thallium-201 DDC as an agent for brain imaging.
PubMed:Differential effects of formamidine pesticides on fixed-interval behavior in rats.
PubMed:The analgesic activity of a clonidine analog. The formamidine, U-47,476A.
PubMed:Induction of hepatic drug-metabolising enzymes following treatment of rats and mice with chlordimeform.
PubMed:Yohimbine attenuates the delayed lethality induced in mice by amitraz, a formamidine pesticide.
PubMed:Thermoregulation in mice following acute chlordimeform administration.
PubMed:Monoamine oxidase inhibition cannot account for changes in visual evoked potentials produced by chlordimeform.
PubMed:Interactions of permeant cations with sodium channels of squid axon membranes.
PubMed:Receptors for 3H-octopamine in the adult firefly light organ.
PubMed:Body temperature-dependent and independent actions of chlordimeform on visual evoked potentials and axonal transport in optic system of rat.
PubMed:The preparation of carbon-11 labelled proline for positron emission tomography. Preliminary distribution studies in rats with Walker 256 carcinosarcoma.
PubMed:Effects of chlordimeform on cardiovascular functional parameters: Part 1. Lethality and arrhythmogenicity in the geriatric rat.
PubMed:Suppression of the antibody response by a formamidine pesticide: dependence on the route of exposure.
PubMed:Formamidine-mediated inhibition of rat platelet aggregation.
PubMed:Mifentidine: evaluation of antiandrogen effects and kidney function studies.
PubMed:Conformational studies of two histamine H2-receptor antagonistic phenylformamidines: mifentidine and its guanidinothiazole analogue DA 4643.
PubMed:Chlordimeform produces profound, selective, and transient changes in visual evoked potentials of hooded rats.
PubMed:The pharmacokinetics of imipenem (thienamycin-formamidine) and the renal dehydropeptidase inhibitor cilastatin sodium in normal subjects and patients with renal failure.
PubMed:Effect of amitraz and chlordimeform on heart rate and pupil diameter in rats: mediated by alpha 2-adrenoreceptors.
PubMed:(Imidazolylphenyl)formamidines. A structurally novel class of potent histamine H2 receptor antagonists.
PubMed:Relaxation of rabbit aorta by chlordimeform.
PubMed:Hot atoms in cosmic chemistry.
PubMed:Metabolism of four thiobis(formamidine) insecticides in the mouse and the rat.
PubMed:Some effects of the formamidine pesticide chlordimeform on the behavior of mice.
PubMed:Permeability to various cations of the voltage-dependent sodium channel of rat single heart cells.
PubMed:5-Hydroxytryptamine stimulates fluid secretion in locust malpighian tubules independently of cAMP.
PubMed:Extrapolation from safety data to management of poisoning with reference to amitraz (a formamidine pesticide) and xylene.
PubMed:Animal studies on the treatment of poisoning by amitraz (a formamidine pesticide) and xylene.
PubMed:A randomized study comparing clinical efficacy and safety of thienamycin formamidine (MK0787)/renal dipeptidase inhibitor (MK0791) and cefazolin.
PubMed:Northienamycin and 8-epi-thienamycin, new carbapenems from Streptomyces cattleya.
PubMed:Experimental studies of drug-induced impaction colic in the horse.
PubMed:Potential neuromuscular toxicity of N'-(2,4-xylyl)-N-methyl formamidine HCl in rodents.
PubMed:Perturbation of hydrogen bonds in the adenine . thymine base pair by Na+: A quantum chemical study.
PubMed:Synthesis of N'-aryl-N3-(substituted)-alpha, alpha'-thio-bis-formamidine dihydrochlorides and their effect on blood sugar level of albino rats.
PubMed:Effects of Selected Insecticides and Nematicides on the In Vitro Development of the Entomogenous Nematode Neoaplectana carpocapsae.
PubMed:Interaction of formamidines with the platelet 5-hydroxytryptamine uptake system.
PubMed:The influence of reducing agents on the composition of 99Tc-complexes: implications for 99mTc-radiopharmaceutical preparation.
PubMed:Effect of amitraz on contractions of the guinea-pig ileum in vitro.
PubMed:Reduction of aspirin-induced ulcers by a new imidazoline anti-inflammatory agent.
PubMed:Inhibition of rat platelet 5-hydroxytryptamine uptake by chlordimeform.
PubMed:Transport of ammonium and methylammonium ions by Azotobacter vinelandii.
PubMed:Response of adrenal catecholamine to a newly synthesized chemical radioprotector.
PubMed:Excretion balance, metabolic fate and tissue residues following treatment of rats with amitraz and N'-(2,4-dimethylphenyl)-N-methylformamidine.
PubMed:The use of formamidine sulphinic acid in the preparation of 99mTc-labelled radiopharmaceuticals--a cautionary note.
PubMed:Action of formamidine pesticides on octopamine receptors.
PubMed:Pharmacological modulation of edema mediated by prostaglandin, serotonin and histamine.
PubMed:Trial of a new compound as a chemical radioprotector and its effect on melatonin.
PubMed:Anti-inflammatory and analgesic profile of amidines of 3-amino-1,2,4-benzotriazine and 3-amino-1,2,4-benzotriazine-1-oxide.
PubMed:The effects of U-40481, demethylchlordimeform, and formetanate on calcium flux in the isolated rabbit aorta.
PubMed:Formamidine pesticides: octopamine-like actions in a firefly.
PubMed:A survey of reducing agents for the synthesis of tetraphenylarsonium oxotechnetiumbis(ethanedithiolate) from [99Tc] pertechnetate in aqueous solution.
PubMed:Preparation of technetium-99m glucoheptonate utilizing formamidine sulfinic acid.
PubMed:Cation selectivity of acetylcholine-activated ionic channel of frog endplate.
PubMed:Thiourea and cyanamide as inhibitors of thyroid peroxidase: the role of iodide.
PubMed:Mode of action of formamidine pesticides: an evaluation of monoamine oxidase as the target.
PubMed:Prostaglandin synthesis inhibited by formamidine pesticides.
PubMed:Increased feeding in rats treated with chlordimeform and related formamidines: a new class of appetite stimulants.
PubMed:Evaluation of formamidine sulfinic acid and other reducing agents for use in the preparation of Tc-99m labeled radiopharmaceuticals.
PubMed:Formamidine acaricides. Toxicity and metabolism studies with twospotted spider mites, Tetranychus urticae Koch.
PubMed:Cation permeability ratios of sodium channels in normal and grayanotoxin-treated squid axon membranes.
PubMed:Permeability of the sodium channel in Myxicola to organic cations.
PubMed:Chemistry and toxicology of quinoxaline, organotin, organofluorine, and formamidine acaricides.
PubMed:Chemistry, biological activity, and uses of formamidine pesticides.
PubMed:Formamidine acaricides: toxicological studies with the cattle tick.
PubMed:Studies on models for tetrahydrofolic acid. V.A. kinetically significant transport process in general base catalyzed aminolysis of a formamidine.
PubMed:Toxicity to Boophilus microplus of formamidine acaricides and related compounds, and modification of toxicity by certain insecticide synergists.
PubMed:[Inhibition of serum transamidinase by formamidine disulfide: identification of the SH-group in the active center of the enzyme].
PubMed:The permeability of the sodium channel to organic cations in myelinated nerve.
PubMed:[Formamidine derivatives of anthelmintic effect. (Preliminary report)].
PubMed:On the pharmacological characteristic of some pyridine derivatives of formamidine and the relationship of their structure and action.
PubMed:Pharmacological assaying of some compounds of the formamidine group.
PubMed:FORMAMIDINE SULFINIC ACID AS A BIOCHEMICAL REDUCING AGENT.
PubMed:Formamidine group transfer in extracts of human pancreas, liver, and kidney.
PubMed:Inhibition of sulfhydryl enzymes by formamidine disulfide.
PubMed:The reaction of ketones with formamidine disulfide.
PubMed:Oxidation-reduction potentials of thiol-dithio systems: thiourea-formamidine disulfide.
PubMed:Synthesis of 4-hydroxyquinolines; a modified preparation through bis-(m-chlorophenyl)-formamidine.
 
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