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benfuracarb
2-methyl-4-(1-methylethyl)-7-oxo-8-oxa-3-thia-2,4-diazadecanoic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester

Supplier Sponsors

CAS Number: 82560-54-1Picture of molecule3D/inchi
Other(deleted CASRN):88650-68-4
FDA UNII: 807671FRZY
Nikkaji Web:J42.319J
Beilstein Number:8347990
MDL:MFCD00210247
XlogP3:4.20 (est)
Molecular Weight:410.53410000
Formula:C20 H30 N2 O5 S
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Scholar: with word "volatile"Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 496.20 °C. @ 760.00 mm Hg (est)
Flash Point: 489.00 °F. TCC ( 253.90 °C. ) (est)
logP (o/w): 4.300
Soluble in:
 water, 8 mg/L @ 20 °C (exp)
 water, 0.5604 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
benfuracarb 95%
Santa Cruz Biotechnology
For experimental / research use only.
Benfuracarb
Sigma-Aldrich
For experimental / research use only.
Benfuracarb PESTANAL®, analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-chicken LD50 92 mg/kg
Japan Pesticide Information. Vol. (54), Pg. 23, 1989.

oral-dog LD50 300 mg/kg
Pesticide Manual. Vol. 9, Pg. 57, 1991.

oral-mouse LD50 102 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 14, Pg. 517, 1989.

oral-rat LD50 105 mg/kg
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 14, Pg. 517, 1989.

Dermal Toxicity:
subcutaneous-mouse LD50 288 mg/kg
"International Congress of Plant Protection, Proceedings of a Conference: Plant Protection fo Human Welfare, 10th, Brighton, UK, Nov. 20-25, 1983" Vol. 1, Pg. 360, 1983.

skin-rat LD50 > 2000 mg/kg
Pesticide Manual. Vol. 9, Pg. 57, 1991.

Inhalation Toxicity:
inhalation-rat LC50 240 mg/m3/4H
Defense des Vegetaux. Vol. 38, Pg. 3, 1984.

 
Safety in Use Information:
Category:
herbicides / pesticides
Recommendation for benfuracarb usage levels up to:
 not for fragrance use.
 
Recommendation for benfuracarb flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Reasoned opinion on the review of the existing MRLs for carbofuran, carbosulfan, benfuracarb and furathiocarb and the setting of an import tolerance for carbofuran in cultivated mushrooms
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :54886
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate
Chemidplus:0082560541
RTECS:AY5088000 for cas# 82560-54-1
 
References:
 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):54886
Pubchem (sid):135013812
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C11073
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
b-alanine, N-(((((2,3-dihydro-2,2-dimethyl-7-benzofuranyl)oxy)carbonyl)methyl
b-alanine, N-[[[[(2,3-dihydro-2,2-dimethyl-7-benzofuranyl)oxy]carbonyl]methylamino]thio]-N-(1-methylethyl)-, ethyl ester
 aminofuracarb
2,3-dihydro-2,2-dimethyl-7-benzofuranyl N-[N-[2-(ethoxycarbonyl)ethyl]-N-isopropylsulfenamoyl]-N-methylcarbamate
N-(((((2,3-dihydro-2,2-dimethyl-7-benzofuranyl)oxy)carbonyl)methylamino)thio)-N-(1-methylethyl)-b-alanine, ethyl ester
2,3-dihydro-2,2-dimethylbenzofuran-7-yl N-(N-isopropyl-N-ethoxycarbonylethylaminosulfenyl)-N-methylcarbamate
 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate
 ethyl 3-[{[{[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]carbonyl}(methyl)amino]sulfanyl}(1-methylethyl)amino]propanoate
 ethyl 3-[{[{[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]carbonyl}(methyl)amino]sulfanyl}(isopropyl)amino]propanoate
 ethyl N-[2,3-dihydro-2,2-dimethylbenzofuran-7-yloxycarbonyl(methyl)aminothio]-N-isopropyl-b-alaninate
 ethyl N-{[{[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]carbonyl}(methyl)amino]sulfanyl}-N-isopropyl-b-alaninate
 ethyl N-{[{[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]carbonyl}(methyl)amino]sulfanyl}-N-propan-2-yl-b-alaninate
 furacon
2-methyl-4-(1-methylethyl)-7-oxo-8-oxa-3-thia-2,4-diazadecanoic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
 oncol 10G
 

Articles:

PubMed:Human variation and CYP enzyme contribution in benfuracarb metabolism in human in vitro hepatic models.
PubMed:Comparative metabolism of benfuracarb in in vitro mammalian hepatic microsomes model and its implications for chemical risk assessment.
PubMed:Development of a new QuEChERS method based on dry ice for the determination of 168 pesticides in paprika using tandem mass spectrometry.
PubMed:Kinetics of sorption-desorption of benfuracarb insecticide in mollisols.
PubMed:Fate of benfuracarb insecticide in mollisols and brinjal crop.
PubMed:Multivariate analysis of toxicological and environmental properties of soil nematicides.
PubMed:[Behavior of N-methylcarbamate pesticides during refinement processing of edible oils].
PubMed:Cuticular hydrocarbon profiles in Blattella germanica: effects of halofenozide, boric acid and benfuracarb.
PubMed:Contact and fumigant toxicity of oriental medicinal plant extracts against Dermanyssus gallinae (Acari: Dermanyssidae).
PubMed:Adsorption and degradation of benfuracarb in three soils in Hunan, People's Republic of China.
PubMed:Transformation and ecotoxicity of carbamic pesticides in water.
PubMed:Reproductive effects in German cockroaches by ecdysteroid agonist RH-0345, juvenile hormone analogue methoprene and carbamate benfuracarb.
PubMed:Application of liquid chromatography with electrospray tandem mass spectrometry to the determination of a new generation of pesticides in processed fruits and vegetables.
PubMed:Development of a simultaneous analysis method for carbofuran and its three derivative pesticides in water by GC/MS with temperature programmable inlet on-column injection.
PubMed:Effect of some granular insecticides currently used for the treatment of maize crops (Zea mays) on the survival of inoculated Azospirillum lipoferum.
PubMed:Determination of five pesticide residues in oranges by matrix solid-phase dispersion and liquid chromatography to estimate daily intake of consumers.
PubMed:Blood carbofuran concentrations in suicidal ingestion cases.
PubMed:Development of monoclonal antibody-based immunoassays to the N-methylcarbamate pesticide carbofuran.
PubMed:Flow-injection spectrophotometric determination of phenolic drugs and carbamate pesticides by coupling with diazotized 2,4,6-trimethylaniline.
PubMed:Forensic toxicological implication of acute fatal poisoning cases due to benfuracarb ingestion.
PubMed:Matrix solid-phase dispersion microextraction and determination by high-performance liquid chromatography with UV detection of pesticide residues in citrus fruit.
PubMed:Alternative methods for mechanistic studies in toxicology. Screening of hepatotoxicity of pesticides using freshly isolated and primary cultured hepatocytes and non-liver-derived cells, SIRC cells.
PubMed:Genotoxic evaluation of three heterocyclic N-methylcarbamate pesticides using the mouse bone marrow micronucleus assay and the Saccharomyces cerevisiae strains D7 and D61.M.
PubMed:Antidotal action of atropine sulfate against insecticide benfuracarb poisoning in rats.
PubMed:Effects of benzofuran and seven benzofuran derivatives including four carbamate insecticides in the in vitro porcine brain tubulin assembly assay and description of a new approach for the evaluation of the test data.
PubMed:Control of Heterodera carotae, Ditylenchus dipsaci, and Meloidogyne javanica with Fumigant and Nonfumigant Nematicides.
 
Notes:
a procarbamate insecticide.
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