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Category:herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white crystals (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 95.00 °C. @ 760.00 mm Hg
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| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est)
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| logP (o/w): | 2.380 |
| Soluble in: |
| | water, 330 mg/L @ 20 °C (exp) | | | water, 195.3 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-dog LD50 > 10200 mg/kg
Ciba-Geigy Toxicology Data/Indexes. Vol. -, Pg. -, 1972.
intraperitoneal-mouse LD50 847 mg/kg
Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976.
oral-mouse LD50 2098 mg/kg
Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976.
unreported-quail LD50 565 mg/kg
Farm Chemicals Handbook. Vol. -, Pg. C203, 1991.
intraperitoneal-rat LD50 430 mg/kg
Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976.
oral-rat LD50 2000 mg/kg
World Review of Pest Control. Vol. 9, Pg. 119, 1970.
unreported-rat LD50 3875 mg/kg
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
BEHAVIORAL: ATAXIA
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(3), Pg. 86, 1973.
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| Dermal Toxicity: |
skin-rabbit LD50 > 10200 mg/kg
World Review of Pest Control. Vol. 9, Pg. 119, 1970.
skin-rat LD50 > 3000 mg/kg
Pesticide Manual. Vol. 9, Pg. 584, 1991.
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| Inhalation Toxicity: |
inhalation-rat LC50 > 1100 mg/m3/4H
Pesticide Manual. Vol. 9, Pg. 584, 1991.
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Safety in Use Information:
| Category: | | herbicides / pesticides |
| Recommendation for metobromuron usage levels up to: | | | not for fragrance use.
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| Recommendation for metobromuron flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron
View page or View pdf
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Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for metobromuron in light of confirmatory data
View page or View pdf
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Review of the existing maximum residue levels for metobromuron according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf
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| EPI System: View |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA GENetic TOXicology:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :18290 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| 3-(4-bromophenyl)-1-methoxy-1-methylurea |
| Chemidplus:0003060897 |
| RTECS:YS3325000 for cas# 3060-89-7 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 3-(4- | bromophenyl)-1-methoxy-1-methylurea | | 3-(p- | bromophenyl)-1-methoxy-1-methylurea | | 1-(4- | bromophenyl)-3-methoxy-3-methylurea | | N'-(4- | bromophenyl)-N-methoxy-N-methylurea | | N-(p- | bromophenyl)-N'-methyl-N'-methoxyurea | | | metbromuron | | | metobromurone | | | monobromuron | | | patoran | | | pattonex | | | urea, 3-(p-bromophenyl)-1-methoxy-1-methyl- | | | urea, N'-(4-bromophenyl)-N-methoxy-N-methyl- |
Articles:
| PubMed:Part I: Temporal and spatial distribution of multiclass pesticide residues in lake waters of Northern Greece: application of an optimized SPE-UPLC-MS/MS pretreatment and analytical method. |
| PubMed:Leaching potential of phenylurea herbicides in a calcareous soil: comparison of column elution and batch studies. |
| PubMed:Assessment of the leaching potential of 12 substituted phenylurea herbicides in two agricultural soils under laboratory conditions. |
| PubMed:Mineralisation of the herbicide linuron by Variovorax sp. strain RA8 isolated from Japanese river sediment using an ecosystem model (microcosm). |
| PubMed:Investigation of the inclusion of the herbicide metobromuron in native cyclodextrins by powder X-ray diffraction and isothermal titration calorimetry. |
| PubMed:Analysis of phenylurea herbicides from plants by GC/MS. |
| PubMed:Simultaneous determination of 15 phenylurea herbicides in rice and corn using HPLC with fluorescence detection combined with UV decomposition and post-column derivatization. |
| PubMed:Method development for the determination of selected pesticides on tobacco by high-performance liquid chromatography-electrospray ionisation-tandem mass spectrometry. |
| PubMed:Biomimetic approach to biomembrane models studies: medium influence on the interaction kinetics of some phenylurea derivatives herbicides. |
| PubMed:Monitoring of triazine and phenylurea herbicides in the surface waters of Greece. |
| PubMed:Ambient air concentrations of pesticides used in potato cultivation in Prince Edward Island, Canada. |
| PubMed:Clean up of phenylurea herbicides in plant sample extracts using molecularly imprinted polymers. |
| PubMed:Application of solid-phase microextraction for determining phenylurea herbicides and their homologous anilines from vegetables. |
| PubMed:Investigation of the effect of soil herbicides on the growth and nutrient uptake of potato. |
| PubMed:Influence of UV irradiation on the toxicity of phenylurea herbicides using Microtox test. |
| PubMed:Solid-phase microextraction coupled with high-performance liquid chromatography for the determination of phenylurea herbicides in aqueous samples. |
| PubMed:Multiresidue determination of pesticides in drinking and related waters by solid-phase extraction and liquid chromatography with ultraviolet detection: interlaboratory study. |
| PubMed:Removal of herbicides from liquid media by fungi isolated from a contaminated soil. |
| PubMed:Enrichment and molecular characterization of a bacterial culture that degrades methoxy-methyl urea herbicides and their aniline derivatives. |
| PubMed:Indirect analysis of urea herbicides from environmental water using solid-phase microextraction. |
| PubMed:Multiresidue HPLC methods for phenyl urea herbicides in water. |
| PubMed:Acute metobromuron poisoning with severe associated methemoglobinemia. Identification of four metabolites in plasma and urine by LC-DAD, LC-ESI-MS, and LC-ESI-MS-MS. |
| PubMed:Determination of linuron and related compounds in soil by microwave-assisted solvent extraction and reversed-phase liquid chromatography with UV detection. |
| PubMed:[Methemoglobinemia caused by accidental poisoning with metolachlor and metobromuron]. |
| PubMed:Electrically driven microseparation methods for pesticides and metabolites. II: on-line and off-line preconcentration of urea herbicides in capillary electrochromatography. |
| PubMed:Determination of phenylurea herbicide residues in vegetables by liquid chromatography after gel permeation chromatography and Florisil cartridge cleanup. |
| PubMed:Mixed immunosorbent for selective on-line trace enrichment and liquid chromatography of phenylurea herbicides in environmental waters. |
| PubMed:Adsorption-desorption and leaching of phenylurea herbicides on soils. |
| PubMed:Metobromuron/metolachlor ingestion with late onset methemoglobinemia in a pregnant woman successfully treated with methylene blue. |
| PubMed:Solid-phase extraction followed by high-performance liquid chromatographic analysis for monitoring herbicides in drinking water. |
| PubMed:Determination of linuron in potatoes using capillary column gas chromatography/mass spectrometry. |
| PubMed:Multiresidue method for determining substituted urea herbicides in foods by liquid chromatography. |
| PubMed:[Toxicologic characteristics of several pesticides and standards for them in water]. |
| PubMed:[On the determination of chlorpropham, metobromuron and chlorbromuron residues in drugs of the 2. AB-DDR (author's transl)]. |
| PubMed:[Gas chromatographic determination of chlorpropham, metobromuron and chlorbromuron residues in drugs of the East German Pharmacopoeia, 2d edition]. |
| PubMed:[Thin-layer chromatographic testing of drugs of the East German Pharmacopoeia, 2d edition, metobromuron and chlorbromuron residues]. |
| PubMed:[Chemical weed control in the cropping of medicinal plants. Part 1: Valerian (Valeriana officinalis L.) (author's transl)]. |
| PubMed:Metabolism in human embryonic lung cell cultures of three phenylurea herbicides: chlorotoluron, fluometuron, and metobromuron. |
| PubMed:Degradation of chlorbromuron and related compounds by the fungus Rhizoctonia solani. |
| PubMed:Metabolism of 3-(p-bromophenyl)-1-methoxy-1-methylurea (metobromuron) by selected soil microorganisms. |
| PubMed:Metobromuron: acetylation of the aniline moiety as a detoxification mechanism. |
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3D/inchi