EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dulcoside A
1-O-[(5b,8a,9b,10a,13a)-13-{[6-deoxy-2-O-(b-D-glucopyranosyl)-b-D-mannopyranosyl]oxy}-18-oxokaur-16-en-18-yl]-b-D-glucopyranose

Supplier Sponsors

CAS Number: 64432-06-0Picture of molecule3D/inchi
FDA UNII: BV1X94PJ0P
MDL:MFCD02752302
XlogP3-AA:-0.70 (est)
Molecular Weight:788.88260000
Formula:C38 H60 O17
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 928.40 °C. @ 760.00 mm Hg (est)
Flash Point: 535.00 °F. TCC ( 279.60 °C. ) (est)
logP (o/w): 1.720 (est)
Soluble in:
 water, 97.45 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Dulcosidea 98%
BOC Sciences
For experimental / research use only.
Dulcoside A
Carbosynth
For experimental / research use only.
Dulcoside A
Coompo
For experimental / research use only.
Dulcoside A from Plants ≥97%
Nacalai USA
For experimental / research use only.
Dulcoside A
Sigma-Aldrich
For experimental / research use only.
Dulcoside A analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for dulcoside A usage levels up to:
 not for fragrance use.
 
Recommendation for dulcoside A flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :44564217
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
Chemidplus:0064432060
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):44564217
Pubchem (sid):135312103
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB36708
FooDB:FDB015644
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 stevia rebaudiana
Search Trop Picture
 
Synonyms:
1-O-[(5b,8a,9b,10a,13a)-13-{[6-deoxy-2-O-(b-D-glucopyranosyl)-b-D-mannopyranosyl]oxy}-18-oxokaur-16-en-18-yl]-b-D-glucopyranose
 

Articles:

PubMed:Gene transcription and steviol glycoside accumulation in Stevia rebaudiana under polyethylene glycol-induced drought stress in greenhouse cultivation.
PubMed:Evaluation of the Antihyperglycemic Effect of Minor Steviol Glycosides in Normoglycemic and Induced-Diabetic Wistar Rats.
PubMed:Steviol glycosides in purified stevia leaf extract sharing the same metabolic fate.
PubMed:Comprehensive review on agro technologies of low-calorie natural sweetener stevia (Stevia rebaudiana Bertoni): a boon to diabetic patients.
PubMed:Ultra-HPLC method for quality and adulterant assessment of steviol glycosides sweeteners - Stevia rebaudiana and stevia products.
PubMed:Intensified Separation of Steviol Glycosides from a Crude Aqueous Extract of Stevia rebaudiana Leaves Using Centrifugal Partition Chromatography.
PubMed:Influence of drying method on steviol glycosides and antioxidants in Stevia rebaudiana leaves.
PubMed:Validation of HPLC-UV method for determination of minor glycosides contained in Stevia rebaudiana Bertoni leaves.
PubMed:Efficient regeneration for enhanced steviol glycosides production in Stevia rebaudiana (Bertoni).
PubMed:Quantitation of sweet steviol glycosides by means of a HILIC-MS/MS-SIDA approach.
PubMed:Simultaneous analysis of steviol and steviol glycosides by liquid chromatography with ultraviolet detection on a mixed-mode column: application to Stevia plant material and Stevia-containing dietary supplements.
PubMed:Structures of the novel α-glucosyl linked diterpene glycosides from Stevia rebaudiana.
PubMed:Diterpene glycosides from Stevia rebaudiana.
PubMed:Structures of the novel diterpene glycosides from Stevia rebaudiana.
PubMed:A new diterpene glycoside from Stevia rebaudiana.
PubMed:Two minor diterpene glycosides from the leaves of Stevia rebaudiana.
PubMed:Monitoring stevioside in soju by high-performance liquid chromatography and liquid chromatography/mass spectrometry.
PubMed:Inhibitory effect of stevioside on tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin.
 
Notes:
Present in Stevia rebaudiana (stevia) extracts 26Mg has found application in isotopic geology, similar to that of aluminium. 26Mg is a radiogenic daughter product of 26Al, which has a half-life of 717,000 years. Large enrichments of stable 26Mg have been observed in the Ca-Al-rich inclusions of some carbonaceous chondrite meteorites. The anomalous abundance of 26Mg is attributed to the decay of its parent 26Al in the inclusions. Therefore, the meteorite must have formed in the solar nebula before the 26Al had decayed. Hence, these fragments are among the oldest objects in the solar system and have preserved information about its early history.; Elemental magnesium is a fairly strong, silvery-white, light-weight metal (two thirds the density of aluminium). It tarnishes slightly when exposed to air, although unlike the alkaline metals, storage in an oxygen-free environment is unnecessary because magnesium is protected by a thin layer of oxide which is fairly impermeable and hard to remove. Like its lower periodic table group neighbor calcium, magnesium reacts with water at room temperature, though it reacts much more slowly than calcium. When it is submerged in water, hydrogen bubbles will almost unnoticeably begin to form on the surface of the metal, though if powdered it will react much more rapidly. The reaction will occur faster with higher temperatures (see precautions). Magnesium also reacts exothermically with most acids, such as hydrochloric acid (HCl). As with aluminium, zinc and many other metals, the reaction with hydrochloric acid produces the chloride of the metal and releases hydrogen gas.; Historically, magnesium was one of the main aerospace construction metals and was used for German military aircraft as early as World War I and extensively for German aircraft in World War II. The Germans coined the name 'Elektron' for magnesium alloy which is still used today. Due to perceived hazards with magnesium parts in the event of fire, the application of magnesium in the commercial aerospace industry was generally restricted to engine related components. Currently the use of magnesium alloys in aerospace is increasing, mostly driven by the increasing importance of fuel economy and the need to reduce weight. The development and testing of new magnesium alloys continues, notably Elektron 21 which has successfully undergone extensive aerospace testing for suitability in engine, internal and airframe components. The European Community runs three R&D magnesium projects in the Aerospace priority of Six Framework Program.; Magnesium (pronounced /mæ??ni?zi?m/) is a chemical element with the symbol Mg, atomic number 12 and common oxidation number +2. It is an alkaline earth metal and the ninth most abundant element in the universe by mass. This preponderance of magnesium is related to the fact that it is easily built up in supernova stars from a sequential addition of three helium nuclei to carbon (which in turn is made from a single reaction between three helium nuclei at once). Magnesium constitutes about 2% of the Earth's crust by mass, which makes it the eighth most abundant element in the crust. Magnesium ion's high solubility in water helps ensure that it is the third most abundant element dissolved in seawater.; Magnesium compounds are typically white crystals. Most are soluble in water, providing the sour-tasting magnesium ion Mg2+. Small amounts of dissolved magnesium ion contribute to the tartness and taste of natural waters. Magnesium ion in large amounts is an ionic laxative, and magnesium sulfate (Epsom salts) is sometimes used for this purpose. So-called "milk of magnesia" is a water suspension of one of the few insoluble magnesium compounds, magnesium hydroxide. The undissolved particles give rise to its appearance and name. Milk of magnesia is a mild base commonly used as an antacid.; Magnesium is a highly flammable metal, but while it is easy to ignite when powdered or shaved into thin strips, it is difficult to ignite in mass or bulk. Once ignited, it is difficult to extinguish, being able to burn in both nitrogen (forming magnesium nitride), and carbon dioxide (forming magnesium oxide and carbon). On burning in air, magnesium produces a brilliant white light. Thus magnesium powder (flash powder) was used as a source of illumination in the early days of photography. Later, magnesium ribbon was used in electrically ignited flash bulbs. Magnesium powder is used in the manufacture of fireworks and marine flares where a brilliant white light is required. Flame temperatures of magnesium and magnesium alloys can reach 1,371 °C (2,500 °F), although flame height above the burning metal is usually less than 300 mm (12 in).; Magnesium is a vital component of a healthy human diet. Human magnesium deficiency (including conditions which show few overt symptoms) is relatively common, with only 32% of the United States meeting the RDA-DRI, and has been implicated in the development of a number of human illnesses such as asthma, osteoporosis, and ADHD.; Magnesium salts are essential in nutrition, being required for the activity of many enzymes, especially those concerned with oxidative phosphorylation. Physiologically, it exists as an ion in the body. It is a component of both intra- and extracellular fluids and is excreted in the urine and feces. Deficiency causes irritability of the nervous system with tetany, vasodilatation, convulsions, tremors, depression, and psychotic behavior. Magnesium ion in large amounts is an ionic laxative, and magnesium sulfate (Epsom salts) is sometimes used for this purpose. So-called "milk of magnesia" is a water suspension of one of the few insoluble magnesium compounds, magnesium hydroxide; There are a number of magnesium dietary supplements available. Magnesium oxide, one of the most common because it has high magnesium content per weight, has been reported to be the least bioavailable. Magnesium citrate has been reported as more bioavailable than oxide or amino-acid chelate (glycinate) forms.; the undissolved particles give rise to its appearance and name. Milk of magnesia is a mild base, and is commonly used as an antacid.
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