EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

(+)-catechin hydrate

Supplier Sponsors

CAS Number: 88191-48-4Picture of molecule3D/inchi
FDA UNII: Search
Molecular Weight:308.28692000
Formula:C15 H16 O7
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
(+)-Catechin Hydrate > 95%
Odor: characteristic
Use: Catechin is a flavan-3-ol, a type of natural phenol and antioxidant. It is a plant secondary metabolite. It belongs to the group of flavan-3-ols (or simply flavanols), part of the chemical family of flavonoids.
Nacalai USA
For experimental / research use only.
(+)-Catechin Hydrate [(+)-C]
Santa Cruz Biotechnology
For experimental / research use only.
(+)-Catechin Hydrate >98%
Sigma-Aldrich: Sigma
For experimental / research use only.
(+)-Catechin Hydrate ≥98% (HPLC), powder
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for (+)-catechin hydrate usage levels up to:
 not for fragrance use.
 
Recommendation for (+)-catechin hydrate flavor usage levels up to:
 not for flavor use.
 
Safety References:
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :107957
National Institute of Allergy and Infectious Diseases:Data
(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol;hydrate
Chemidplus:0088191484
 
References:
 (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol;hydrate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):107957
Pubchem (sid):135066037
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):D00200
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 tea green tea
Search Trop Picture
 
Synonyms:
2H-1-benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R,3S)-, hydrate (1:1)
2H-1-benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, monohydrate, (2R,3S)-
(+)-catechin monohydrate
(+)-cyanidol-3
(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol
(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol;hydrate
(2R,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-chromanetriol hydrate (1:1)
(2R,3S)-2-(3,4-dihydroxyphenyl)-chroman-3,5,7-triol hydrate
(2R,3S)-2-(3,4-dihydroxyphenyl)chroman-3,5,7-triol hydrate
(2R,3S)-2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol hydrate (1:1)
 

Articles:

PubMed:Establishment of drug delivery system nanocapsulated with an antioxidant (+)-catechin hydrate and sodium meta borate chelator against sodium fluoride induced oxidative stress in rats.
PubMed:Antioxidant and Anti-Inflammatory Activity Determination of One Hundred Kinds of Pure Chemical Compounds Using Offline and Online Screening HPLC Assay.
PubMed:Pharmacognostic evaluation with reference to catechin content and antioxidant activities of pale catechu in Thailand.
PubMed:Effect of polyphenols on reactive oxygen species production and cell growth of human dermal fibroblasts after irradiation with ultraviolet-A light.
PubMed:Phenolic compounds, antioxidant activity and insulinotropic effect of extracts prepared from grape (Vitis vinifera L) byproducts.
PubMed:Analysis of phenolic compounds in commercial dried grape pomace by high-performance liquid chromatography electrospray ionization mass spectrometry.
PubMed:Delineating the anti-cytotoxic and anti-genotoxic potentials of catechin hydrate against cadmium toxicity in human peripheral blood lymphocytes.
PubMed:Nephroprotective effect of catechin on gentamicin-induced experimental nephrotoxicity.
PubMed:Flavonoids and 5-aminosalicylic acid inhibit the formation of neutrophil extracellular traps.
PubMed:Simultaneous determination of phenolic compounds in Cynthiana grape (Vitis aestivalis) by high performance liquid chromatography-electrospray ionisation-mass spectrometry.
PubMed:Effect of (+)-catechin hydrate on oxidative stress induced by high sucrose and high fat diet in male Wistar rats.
PubMed:Catechin averts experimental diabetes mellitus-induced vascular endothelial structural and functional abnormalities.
PubMed:Inhibition of urease activity in the urinary tract pathogen Staphylococcus saprophyticus.
PubMed:A novel inhibitor, 16-hydroxy-cleroda-3,13-dien-16,15-olide, blocks the autophosphorylation site of focal adhesion kinase (Y397) by molecular docking.
PubMed:Amelioration of cognitive impairment and neurodegeneration by catechin hydrate in rat model of streptozotocin-induced experimental dementia of Alzheimer's type.
PubMed:HPLC determination of phenolic acids, flavonoids and juglone in walnut leaves.
PubMed:Engineering the production of major catechins by Escherichia coli carrying metabolite genes of Camellia sinensis.
PubMed:Catechin hydrate ameliorates redox imbalance and limits inflammatory response in focal cerebral ischemia.
PubMed:Catechin hydrate inhibits proliferation and mediates apoptosis of SiHa human cervical cancer cells.
PubMed:A novel retinoic acid, catechin hydrate and mustard oil-based emulsion for enhanced cytokine and antibody responses against multiple strains of HIV-1 following mucosal and systemic vaccinations.
PubMed:Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis.
PubMed:Ascorbate improves metabolic abnormalities in Wrn mutant mice but not the free radical scavenger catechin.
PubMed:Antioxidant activity and phenolic content of betalain extracts from intact plants and hairy root cultures of the red beetroot Beta vulgaris cv. Detroit dark red.
PubMed:Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons.
PubMed:Development of a potential reference material for evaluating antioxidant activity.
PubMed:Distinct mechanisms underlie distinct polyphenol-induced neuroprotection.
PubMed:Effects of varied EGCG and (+)-catechin concentrations on proinflammatory cytokines mrna expression in cona-stimulated primary white blood cell cultures.
PubMed:Carbon-13 CP-MAS nuclear magnetic resonance studies of teas.
PubMed:Effect of dietary catechin and vitamin E on aortic fatty streak accumulation in hypercholesterolemic hamsters.
PubMed:Screening for agents inhibiting the mutagenicity of extracts and constituents of tobacco products.
 
Notes:
None found
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