EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

decoquinate
ethyl 6-decyloxy-7-ethoxy-4-hydroxy-3-quinolinate

Supplier Sponsors

CAS Number: 18507-89-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:242-389-1
FDA UNII: 534I52PVWH
Nikkaji Web:J10.996G
MDL:MFCD00673686
XlogP3-AA:6.80 (est)
Molecular Weight:417.54595000
Formula:C24 H35 N O5
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 517.90 °C. @ 760.00 mm Hg (est)
Flash Point: 513.00 °F. TCC ( 267.00 °C. ) (est)
logP (o/w): 8.740 (est)
Soluble in:
 water, 0.0005194 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Decoquinate >98%
Odor: characteristic
Use: Decoquinate is a feed additive intended for the control of coccidiosis, a debilitating protozoal infection in poultry.
Sigma-Aldrich
For experimental / research use only.
Decoquinate VETRANAL™
analytical standard
TCI AMERICA
For experimental / research use only.
Decoquinate >97.0%(HPLC)(N)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for decoquinate usage levels up to:
 not for fragrance use.
 
Recommendation for decoquinate flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific opinion on the modification of authorisation of Deccox® (decoquinate) as feed additive for chickens for fattening
View page or View pdf

Scientific Opinion on the modification of the terms of authorisation of Avi-Deccox® 60G (decoquinate) for chickens for fattening
View page or View pdf

EPI System: View
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :29112
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
ethyl 6-decoxy-7-ethoxy-4-oxo-1H-quinoline-3-carboxylate
Chemidplus:0018507896
RTECS:VB1983800 for cas# 18507-89-6
 
References:
 ethyl 6-decoxy-7-ethoxy-4-oxo-1H-quinoline-3-carboxylate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):29112
Pubchem (sid):134993515
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEMBL:View
KEGG (GenomeNet):D03667
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 deccox
 decoquinato
 decoquinatum
6-decyloxy-7-ethoxy-4-hydroxy-3-quinolinecarboxylic acid ethyl ester
6-decyloxy-7-ethoxy-4-hydroxy-quinoline-3-carboxylic acid ethyl ester
 ethyl 6-(decyloxy)-7-ethoxy-4-hydroxy-3-quinolinecarboxylate
 ethyl 6-(decyloxy)-7-ethoxy-4-hydroxyquinoline-3-carboxylate
 ethyl 6-(N-decyloxy)-7-ethoxy-4-hydroxyquinoline-3-carboxylate
 ethyl 6-decoxy-7-ethoxy-4-oxo-1H-quinoline-3-carboxylate
 ethyl 6-decyloxy-7-ethoxy-4-hydroxy-3-quinolinate
 ethyl 6-decyloxy-7-ethoxy-4-oxohydroquinoline-3-carboxylate
3-quinolinecarboxylic acid, 6- (decyloxy)-7-ethoxy-4-hydroxy-, ethyl ester
3-quinolinecarboxylic acid, 6-(decyloxy)-7-ethoxy-4-hydroxy-, ethyl ester
 

Articles:

PubMed:Evaluation of essential oils and prebiotics for newborn dairy calves.
PubMed:Relationship Between Broiler Body Weights, Eimeria maxima Gross Lesion Scores, and Microscores in Three Anticoccidial Sensitivity Tests.
PubMed:Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites.
PubMed:Genetic diversity and drug sensitivity studies on Eimeria tenella field isolates from Hubei Province of China.
PubMed:Technical note: Evaluating nuclear magnetic resonance spectroscopy for determining body composition in Holstein dairy calves using deuterium oxide dilution methods.
PubMed:Coccidiosis in the Chukar Partridge ( Alectoris chukar ): A Survey of Coccidiosis Outbreaks and a Test of Anticoccidial Drugs Against Eimeria kofoidi.
PubMed:Nitrogen utilization, preweaning nutrient digestibility, and growth effects of Holstein dairy calves fed 2 amounts of a moderately high protein or conventional milk replacer.
PubMed:A multi-residue method for 17 anticoccidial drugs and ractopamine in animal tissues by liquid chromatography-tandem mass spectrometry and time-of-flight mass spectrometry.
PubMed:Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activities.
PubMed:Efficacy of treatment of elevated coccidial oocyst counts in goats using amprolium versus ponazuril.
PubMed:Growth, ruminal measurements, and health characteristics of Holstein bull calves fed an Aspergillus oryzae fermentation extract.
PubMed:Determination of fifteen coccidiostats in feed at carry-over levels using liquid chromatography-mass spectrometry.
PubMed:Deposition and depletion of decoquinate in eggs after administration of cross-contaminated feed.
PubMed:New insight-guided approaches to detect, cure, prevent and eliminate malaria.
PubMed:High-throughput screening of FDA-approved drugs using oxygen biosensor plates reveals secondary mitofunctional effects.
PubMed:Development and validation of a multiresidue liquid chromatography/tandem mass spectrometry method for 11 coccidiostats in feed.
PubMed:Herd-level risk factors associated with fecal shedding of Shiga toxin-encoding bacteria on dairy farms in Minnesota, USA.
PubMed:Detection of veterinary drug residues in surface waters collected nearby farming areas in Galicia, North of Spain.
PubMed:Nanoparticle formulations of decoquinate increase antimalarial efficacy against liver stage Plasmodium infections in mice.
PubMed:Formulation and particle size reduction improve bioavailability of poorly water-soluble compounds with antimalarial activity.
PubMed:Determination of 20 coccidiostats in milk, duck muscle and non-avian muscle tissue using UHPLC-MS/MS.
PubMed:Efficacy of decoquinate against Sarcocystis neurona in cell cultures.
PubMed:Development of transgenic lines of Eimeria tenella expressing M2e-enhanced yellow fluorescent protein (M2e-EYFP).
PubMed:Development and validation of a liquid chromatographic-tandem mass spectrometric method for determination of eleven coccidiostats in milk.
PubMed:The history of decoquinate in the control of coccidial infections in ruminants.
PubMed:Use of coccidiostat in mineral salt and study on ovine eimeriosis.
PubMed:Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug.
PubMed:Detection and quantitative analysis of 21 veterinary drugs in river water using high-pressure liquid chromatography coupled to tandem mass spectrometry.
PubMed:Residue depletion of decoquinate in chicken tissues after oral administration.
PubMed:Effect of dietary antimicrobials on immune status in broiler chickens.
PubMed:Medicating feeds for early lambing ewes.
PubMed:Severe myositis associated with Sarcocystis spp. infection in 2 dogs.
PubMed:A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor.
PubMed:Development and validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for eleven coccidiostats in eggs.
PubMed:Determination of eleven coccidiostats in animal feed by liquid chromatography-tandem mass spectrometry at cross contamination levels.
PubMed:Perspectives on canine and feline hepatozoonosis.
PubMed:The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites.
PubMed:Treatment of Hepatozoon americanum infection: review of the literature and experimental evaluation of efficacy.
PubMed:Risk assessment of coccidostatics during feed cross-contamination: animal and human health aspects.
PubMed:Multi-residue method for detecting coccidiostats at carry-over level in feed by HPLC-MS/MS.
PubMed:Oral pharmacokinetics and milk residues of decoquinate in milking cows.
PubMed:Multi-residue confirmatory method for the determination of twelve coccidiostats in chicken liver using liquid chromatography tandem mass spectrometry.
PubMed:Supply of Deccox 25 Individual Treatment Packs.
PubMed:Determination of decoquinate in animal feeds by liquid chromatography: collaborative study.
PubMed:Ovine toxoplasmosis: transmission, clinical outcome and control.
PubMed:A laboratory method for the single-passage selection of drug-resistant mutants from populations of Eimeria species in chickens and its potential value in the choice of field use concentrations for new anticoccidial drugs.
PubMed:Analysis of the phenotypes in field populations of Eimeria acervulina expressing dual drug-resistance to decoquinate and clopidol.
PubMed:Efficacy of decoquinate against drug sensitive laboratory strains of Eimeria tenella and field isolates of Eimeria spp. in broiler chickens in China.
PubMed:Field study of the efficacy of halofuginone and decoquinate in the treatment of cryptosporidiosis in veal calves.
PubMed:Effect of the quinolone coccidiostat decoquinate on the rearrangement of chromosomes of Eimeria tenella.
PubMed:Relative virulences of a drug-resistant and a drug-sensitive strain of Eimeria acervulina, a coccidium of chickens.
PubMed:Tracing the emergence of drug-resistance in coccidia (Eimeria spp.) of commercial broiler flocks medicated with decoquinate for the first time in the United Kingdom.
PubMed:Effect of different decoquinate treatments on cryptosporidiosis in naturally infected cashmere goat kids.
PubMed:Questions limitation in treatment of hepatozoonosis.
PubMed:Prophylactic use of decoquinate for infections with Cryptosporidium parvum in experimentally challenged neonatal calves.
PubMed:Efficacy of selected oral chemotherapeutants against Ichthyophthirius multifiliis (Ciliophora: Ophyroglenidae) infecting rainbow trout Oncorhynchus mykiss.
PubMed:Monitoring of domestic and imported eggs for veterinary drug residues by the Canadian Food Inspection Agency.
PubMed:Treatment of dogs infected with Hepatozoon americanum: 53 cases (1989-1998).
PubMed:Activity of decoquinate against Cryptosporidium parvum in cell cultures and neonatal mice.
PubMed:Cytochrome b mutation identified in a decoquinate-resistant mutant of Toxoplasma gondii.
PubMed:Decoquinate induces tissue cyst formation by the RH strain of Toxoplasma gondii.
PubMed:Protozoan infections (Toxoplasma gondii, Neospora caninum and Sarcocystis spp.) in sheep and goats: recent advances.
PubMed:Evaluation of decoquinate to treat experimental cryptosporidiosis in kids.
PubMed:The mode of action of anticoccidial quinolones (6-decyloxy-4-hydroxyquinoline-3-carboxylates) in chickens.
PubMed:Efficacy of decoquinate against Neospora caninum tachyzoites in cell cultures.
PubMed:Decoquinate and the control of experimental ovine toxoplasmosis.
PubMed:A descriptive epidemiological study of coccidiosis in early lambing housed flocks.
PubMed:Sensitivity of field isolates of Eimeria from two broiler complexes to anticoccidial drugs in the chicken.
PubMed:Efficacy of lasalocid and decoquinate against coccidiosis in naturally infected dairy calves.
PubMed:Toxoplasma gondii: susceptibility and development of resistance to anticoccidial drugs in vitro.
PubMed:Mutants of Toxoplasma gondii resistant to atovaquone (566C80) or decoquinate.
PubMed:In vivo expression of in vitro anticoccidial activity.
PubMed:Estimation of relative fecundity in Eimeria tenella strains by a mixed infection method.
PubMed:Evaluation of decoquinate or lasalocid against coccidiosis from natural exposure in neonatal dairy calves.
PubMed:Evaluation of anticoccidial drugs in chicken embryos.
PubMed:Coccidiosis and cryptosporidiosis in sheep and goats.
PubMed:Influence of decoquinate fed to neonatal dairy calves on early and conventional weaning systems.
PubMed:Alteration of neutrophil function associated with coccidiosis in cattle: influence of decoquinate and dexamethasone.
PubMed:Evaluation of lasalocid and decoquinate against coccidiosis resulting from natural exposure in weaned dairy calves.
PubMed:Effects of inoculations with Eimeria zuernii on young calves treated with decoquinate or narasin with or without dexamethasone.
PubMed:Effects of intermittent and continuous administration of decoquinate on bovine coccidiosis in male calves.
PubMed:Alternative to monensin in sheep.
PubMed:Metabolism of decoquinate in chickens and Japanese quail.
PubMed:Glucose phosphate isomerase isozymes as genetic markers for lines of Eimeria tenella.
PubMed:Comparative drug depletion in domestic animals and birds.
PubMed:The extraintestinal stages of Eimeria tenella and E. maxima in the chicken.
PubMed:Influence of decoquinate on ruminal fermentation, diet digestibility and cattle performance.
PubMed:Coccidiosis in sheep and goats.
PubMed:Evaluation of lasalocid as a coccidiostat in calves: titration, efficacy, and comparison with monensin and decoquinate.
PubMed:Comparative metabolism of 14C-decoquinate in chickens, quail and sheep.
PubMed:Evaluation of decoquinate, lasalocid, and monensin against experimentally induced sarcocystosis in calves.
PubMed:Experimental development of resistance to decoquinate and robenidine in a multiple drug-resistant strain of Eimeria necatrix.
PubMed:Prevention and control of coccidiosis in goats with decoquinate.
PubMed:Effect of decoquinate on the control of coccidiosis in young ruminating calves.
PubMed:Eimeria tenella: stability of resistance to halofuginone, decoquinate and arprinocid in the chicken.
PubMed:Eimeria tenella: relative survival of drug-resistant and drug-sensitive populations in floor pen chickens.
PubMed:Eimeria tenella: immunogenicity of arrested sporozoites in chickens.
PubMed:Eimeria tenella: development of resistance to arprinocid and decoquinate in the chicken.
PubMed:Potent and selective hydroxynaphthoquinone inhibitors of mitochondrial electron transport in Eimeria tenella (Apicomplexa: Coccidia).
PubMed:Bovine coccidiosis: protective effects of low-level infection and coccidiostat treatments in calves.
PubMed:Effects of decoquinate and clopidol on electron transport in mitochondria of Eimeria tenella (Apicomplexa: Coccidia).
PubMed:Development by genetic recombination of a line of Eimeria tenella resistant to robenidine, decoquinate and amprolium.
PubMed:[Not Available].
PubMed:Coccidiostat residues in poultry excreta.
PubMed:Determination of decoquinate in poultry feed.
PubMed:Porcine neonatal coccidiosis.
PubMed:Resistance and cross-resistance studies with narasin, a new polyether antibiotic anticoccidial drug.
PubMed:Mutagenicity screening of feed additives in the microbial system.
PubMed:Factors influencing the assessment of anticoccidial activity in cell culture.
PubMed:Bovine coccidiosis. A review, including field safety studies with decoquinate for prevention.
PubMed:Development of immunity to coccidiosis in chickens administered anticoccidials in feed.
PubMed:Eimeria tenella: inhibition of development in cell culture by serum from chickens fed anticoccidial drugs.
PubMed:Studies on the growth, chemotherapy and enzyme variation of Eimeria acervulina var. diminuta and E. acervulina var. mivati.
PubMed:The influence of monensin sodium upon feather development of male chickens.
PubMed:Further studies on the use of chicken embryo infections for the study of drug resistance in Eimeria tenella.
PubMed:Anticoccidial drugs: effects on infectivity and survival intracellularly of Eimeria tenella sporozoites.
PubMed:Genetic recombination of precociousness and anticoccidial drug resistance in Eimeria tenella.
PubMed:Reduction of anticoccidial drug resistance by massive introduction of drug-sensitive coccidia.
PubMed:Decoquinate in the control of experimentally induced coccidiosis of calves.
PubMed:The short-term toxicity of some feed additives to different freshwater organisms.
PubMed:Studies of the mitochondria from Eimeria tenella and inhibition of the electron transport by quinolone coccidiostats.
PubMed:Lasalocid: resistance and cross-resistance studies in Eimeria tenella-infected chicks.
PubMed:The determination of decoquinate in animal feeds.
PubMed:Drug residues in animal tissues. Fluorometric determination of decoquinate in chicken tissues.
PubMed:Presence of residues in eggs laid by chickens receiving decoquinate.
PubMed:The presence of residues in the tissues of rats receiving decoquinate orally.
PubMed:The disposition of decoquinate- 14 C administered orally to chickens.
PubMed:Efficacy of decoquinate against eleven strains of Eimeria tenella and development of a decoquinate-resistant strain.
PubMed:Decoquinate. Estimation of residues in chicken tissues before and after cooking.
PubMed:Estimation of decoquinate residues in chicken tissues by thin-layer chromatography and measurement of fluorescence on plates.
PubMed:Decoquinate. II. Absorption and residue studies in chickens.
PubMed:Decoquinate. I. An absorption and elimination study in broiler chickens using 14C-labelled decoquinate.
 
Notes:
a coccidiostat for poultry.
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy