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Category:antimicrobial agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white to pale yellow powder (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | antimicrobial agents |
| Recommendation for hops beta acids usage levels up to: | | | not for fragrance use.
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| Recommendation for hops beta acids flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
Articles:
| PubMed:Inhibition of fructan-fermenting equine faecal bacteria and Streptococcus bovis by hops (Humulus lupulus L.) β-acid. |
| PubMed:Quantitative genetic parameters for yield, plant growth and cone chemical traits in hop (Humulus lupulus L.). |
| PubMed:In vitro and in vivo antioxidant and antimutagenic activities of polyphenols extracted from hops (Humulus lupulus L.). |
| PubMed:Hexahydro-β-acids potently inhibit 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice. |
| PubMed:Metabolism of hop-derived bitter acids. |
| PubMed:Beer and beer compounds: physiological effects on skin health. |
| PubMed:Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice. |
| PubMed:Comparative proteomic profiling in compatible and incompatible interactions between hop roots and Verticillium albo-atrum. |
| PubMed:Empiric mathematical model for predicting the content of alpha-acids in hop (Humulus lupulus L.) cv. Aurora. |
| PubMed:Isoprene synthase genes form a monophyletic clade of acyclic terpene synthases in the TPS-B terpene synthase family. |
| PubMed:Effects of extracts of Humulus lupulus (hops) and Yucca schidigera applied alone or in combination with monensin on rumen fermentation and microbial populations in vitro. |
| PubMed:Identification and quantification of the oxidation products derived from α-acids and β-acids during storage of hops ( Humulus lupulus L.). |
| PubMed:Comparative analysis of production and purification of homo- and hetero-polysaccharides produced by lactic acid bacteria. |
| PubMed:On the reaction of lupulones, hops β-acids, with 1-hydroxyethyl radical. |
| PubMed:Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro. |
| PubMed:The effects of beta acids from hops (Humulus lupulus) on mortality of Varroa destructor (Acari: Varroidae). |
| PubMed:Effects of hop varieties on ruminal fermentation and bacterial community in an artificial rumen (rusitec). |
| PubMed:Isolation of bitter acids from hops (Humulus lupulus L.) using countercurrent chromatography. |
| PubMed:HlPT-1, a membrane-bound prenyltransferase responsible for the biosynthesis of bitter acids in hops. |
| PubMed:Flavonoid production in transgenic hop (Humulus lupulus L.) altered by PAP1/MYB75 from Arabidopsis thaliana L. |
| PubMed:Survival of Escherichia coli O157:H7 in meat product brines containing antimicrobials. |
| PubMed:LC determination of luteolin-7-O-β-D-glucoside and apigenin-7-O-β-D-glucoside in rat plasma after administration of Humulus scandens extract and its application to pharmacokinetic studies. |
| PubMed:Occurrence of odorant polyfunctional thiols in the Super Alpha Tomahawk hop cultivar. Comparison with the thiol-rich Nelson Sauvin bitter variety. |
| PubMed:High-performance liquid chromatographic determination and pharmacokinetic study of apigenin-7-O-β-D-glucoside in rat plasma after intravenous administration. |
| PubMed:Chicken intestine microbiota following the administration of lupulone, a hop-based antimicrobial. |
| PubMed:Application of plant-based antimicrobials for the growth inhibition of clostridia in pressed beet pulp silage. |
| PubMed:Evaluation of genetic variability of wild hops (Humulus lupulus L.) in Canada and the Caucasus region by chemical and molecular methods. |
| PubMed:Evaluation of brining ingredients and antimicrobials for effects on thermal destruction of Escherichia coli O157:H7 in a meat model system. |
| PubMed:Effects of hops (Humulus lupulus L.) extract on volatile fatty acid production by rumen bacteria. |
| PubMed:Transport of hop bitter acids across intestinal Caco-2 cell monolayers. |
| PubMed:Identification of new phase II metabolites of xanthohumol in rat in vivo biotransformation of hop extracts using high-performance liquid chromatography electrospray ionization tandem mass spectrometry. |
| PubMed:Crystal structure and substrate specificity of plant adenylate isopentenyltransferase from Humulus lupulus: distinctive binding affinity for purine and pyrimidine nucleotides. |
| PubMed:Rho iso-alpha acids from hops inhibit the GSK-3/NF-kappaB pathway and reduce inflammatory markers associated with bone and cartilage degradation. |
| PubMed:Hop bitter acids efficiently block inflammation independent of GRalpha, PPARalpha, or PPARgamma. |
| PubMed:Xanthohumol from hop (Humulus lupulus L.) is an efficient inhibitor of monocyte chemoattractant protein-1 and tumor necrosis factor-alpha release in LPS-stimulated RAW 264.7 mouse macrophages and U937 human monocytes. |
| PubMed:Identification and RP-HPLC-ESI-MS/MS quantitation of bitter-tasting beta-acid transformation products in beer. |
| PubMed:Capillary zone electrophoresis method for determination of bitter (alpha- and beta-) acids in hop (Humulus lupulus L.) cone extracts. |
| PubMed:Control of Listeria monocytogenes on frankfurters by dipping in hops beta acids solutions. |
| PubMed:Hop proanthocyanidins induce apoptosis, protein carbonylation, and cytoskeleton disorganization in human colorectal adenocarcinoma cells via reactive oxygen species. |
| PubMed:LC-MS/MS quantitation of hop-derived bitter compounds in beer using the ECHO technique. |
| PubMed:Antilisterial activity of hops beta acids in broth with or without other antimicrobials. |
| PubMed:Terpene biosynthesis in glandular trichomes of hop. |
| PubMed:Structural basis of human pregnane X receptor activation by the hops constituent colupulone. |
| PubMed:Development of a screening assay for ligands to the estrogen receptor based on magnetic microparticles and LC-MS. |
| PubMed:Protective effect of hop beta-acids on microbial degradation of thick juice during storage. |
| PubMed:Studying the structural properties of polyalanine and polyglutamine peptides. |
| PubMed:Constitutive expression of a grapevine stilbene synthase gene in transgenic hop (Humulus lupulus L.) yields resveratrol and its derivatives in substantial quantities. |
| PubMed:NMR assignment of iso-alpha-acids from isomerised extracts of Humulus lupulus L. cones. |
| PubMed:Chemopreventive effects of lupulone, a hop {beta}-acid, on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis. |
| PubMed:Relevance of organic farming and effect of climatological conditions on the formation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol in hop (Humulus lupulus L.). |
| PubMed:Sensitive electrochemical detection method for alpha-acids, beta-acids and xanthohumol in hops (Humulus lupulus L.). |
| PubMed:Evidence that the beta-acids fraction of hops reduces central GABAergic neurotransmission. |
| PubMed:Sedating effects of Humulus lupulus L. extracts. |
| PubMed:Analysis of hop acids and their oxidized derivatives and iso-alpha-acids in beer by capillary electrophoresis-electrospray ionization mass spectrometry. |
| PubMed:Characterization of the methanolic extract of hops using capillary electrophoresis-electrospray ionization-mass spectrometry. |
| PubMed:Isohumulones modulate blood lipid status through the activation of PPAR alpha. |
| PubMed:Generation of organic acids and monosaccharides by hydrolytic and oxidative transformation of food processing residues. |
| PubMed:Direct characterization of bitter acids in a crude hop extract by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. |
| PubMed:Mechanisms of cancer chemoprevention by hop bitter acids (beer aroma) through induction of apoptosis mediated by Fas and caspase cascades. |
| PubMed:Antiviral activity of hop constituents against a series of DNA and RNA viruses. |
| PubMed:Inhibition of peroxynitrite-mediated LDL oxidation by prenylated flavonoids: the alpha,beta-unsaturated keto functionality of 2'-hydroxychalcones as a novel antioxidant pharmacophore. |
| PubMed:Formation and accumulation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol during flowering of hops (Humulus lupulus L.). |
| PubMed:Comparative chemical attributes of native North American hop, Humulus lupulus var. lupuloides E. Small. |
| PubMed:Mechanism for formation of the lightstruck flavor in beer revealed by time-resolved electron paramagnetic resonance. |
| PubMed:Cloning and analysis of valerophenone synthase gene expressed specifically in lupulin gland of hop (Humulus lupulus L.). |
| PubMed:Phlorisovalerophenone synthase, a novel polyketide synthase from hop (Humulus lupulus L.) cones. |
| PubMed:The effect of colupulone (a HOPS beta-acid) on hepatic cytochrome P-450 enzymatic activity in the rat. |
| PubMed:A modified TnphoA useful for single-stranded DNA sequencing. |
| PubMed:Factors affecting antibacterial activity of hop compounds and their derivatives. |
| PubMed:Slippery runs, shifty stops, backward steps, and forward hops: -2, -1, +1, +2, +5, and +6 ribosomal frameshifting. |
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