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pterostilbene
4-stilbenol, 3',5'-dimethoxy-, (E)-

Sponsors

Name:4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol
CAS Number: 537-42-8Picture of molecule3D/inchi
FDA UNII:26R60S6A5I
Nikkaji Web:J11.562B
MDL:MFCD00238710
XlogP3-AA:3.80 (est)
Molecular Weight:256.30112000
Formula:C16 H16 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:antioxidants, skin conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 420.45 °C. @ 760.00 mm Hg (est)
Flash Point: 407.00 °F. TCC ( 208.10 °C. ) (est)
logP (o/w): 4.056 (est)
Soluble in:
 water, 21.24 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antioxidants
skin conditioning
 
Suppliers:
BOC Sciences
For experimental / research use only.
Pterostilbene >98%
Jiangyin Healthway
Trans-Pterostilbene
New functional food ingredients
Nacalai USA
For experimental / research use only.
Pterostilbene
Sabinsa Corporation
pTeroWhite® 90%
Sigma-Aldrich: Sigma
For experimental / research use only.
Pterostilbene ≥97% (HPLC), solid
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: antioxidants, skin conditioning
Recommendation for pterostilbene usage levels up to:
 not for fragrance use.
 
Recommendation for pterostilbene flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281727
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol
Chemidplus:0000537428
 
References:
 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281727
Pubchem (sid):135114939
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C10287
HMDB (The Human Metabolome Database):Search
FooDB:FDB012375
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 grape leaf
Search Trop Picture
 pterocarpus marsupium wood
Search Trop Picture
 
Synonyms:
(E)-3',5'-dimethoxy-4-stilbenol
3',5'-dimethoxy-4-stilbenol
3,5-dimethoxy-4'-hydroxy-trans-stilbene
3,5-dimethoxy-4'-hydroxystilbene
3',5'-dimethoxy-4E-stilbenol
4-[(E)-2-(3,5-dimethoxy-phenyl)-vinyl]-phenol
4-((E)-2-(3,5-dimethoxyphenyl)ethenyl)phenol
4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol
4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol
4-[(1E)-2-(3,5-dimethoxyphenyl)vinyl]phenol
4-[(E)-2-(3,5-dimethoxyphenyl)vinyl]phenol
(E)-4-(3,5-dimethoxystyryl)phenol
(E)-4'-hydroxy-3,5-dimethoxystilbene
(E)-1-hydroxy-4-(3,5-dimethoxy)styrylbenzene
 phenol, 4-(2-(3,5-dimethoxyphenyl)ethenyl)-, (E)-
 phenol, 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-
 phenol, 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-
 pterostilben
trans-pterostilbene
4-stilbenol, 3',5'-dimethoxy-, (E)-
 

Articles:

PubMed:Pterostilbene mediates neuroprotection against oxidative toxicity via oestrogen receptor α signalling pathways.
PubMed:The emerging role of redox-sensitive Nrf2-Keap1 pathway in diabetes.
PubMed:Potent anti-cancer effect of 3'-hydroxypterostilbene in human colon xenograft tumors.
PubMed:Involvement of the Nrf2 pathway in the regulation of pterostilbene-induced apoptosis in HeLa cells via ER stress.
PubMed:Pterostilbene attenuates the inflammatory reaction induced by ischemia/reperfusion in rat heart.
PubMed:Synthesis of glycosides of resveratrol, pterostilbene, and piceatannol, and their anti-oxidant, anti-allergic, and neuroprotective activities.
PubMed:Protective Effects of Pterostilbene against Acetaminophen-Induced Hepatotoxicity in Rats.
PubMed:Cytotoxicity studies of novel combretastatin and pterostilbene derivatives.
PubMed:Pterostilbene simultaneously induced G0/G1-phase arrest and MAPK-mediated mitochondrial-derived apoptosis in human acute myeloid leukemia cell lines.
PubMed:Estrogen receptor-α36 is involved in pterostilbene-induced apoptosis and anti-proliferation in in vitro and in vivo breast cancer.
PubMed:Anticancer activities of pterostilbene-isothiocyanate conjugate in breast cancer cells: involvement of PPARγ.
PubMed:The berry constituents quercetin, kaempferol, and pterostilbene synergistically attenuate reactive oxygen species: involvement of the Nrf2-ARE signaling pathway.
PubMed:Pterostilbene suppresses oral cancer cell invasion by inhibiting MMP-2 expression.
PubMed:Pterostilbene, a dimethyl ether derivative of resveratrol, reduces fat accumulation in rats fed an obesogenic diet.
PubMed:Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trial.
PubMed:MALDI mass spectrometry imaging for the simultaneous location of resveratrol, pterostilbene and viniferins on grapevine leaves.
PubMed:Pharmacokinetics and tissue distribution of pterostilbene in the rat.
PubMed:Amphiphilic graft copolymers from end-functionalized starches: synthesis, characterization, thin film preparation, and small molecule loading.
PubMed:Anti-proliferative effect of pterostilbene on rat hepatoma cells in culture.
PubMed:The anti-tumor efficiency of pterostilbene is promoted with a combined treatment of Fas signaling or autophagy inhibitors in triple negative breast cancer cells.
PubMed:Proteomic identification of pterostilbene-mediated anticancer activities in HepG2 cells.
PubMed:Regulation of plant immunity through modulation of phytoalexin synthesis.
PubMed:Fatty acid synthase methylation levels in adipose tissue: effects of an obesogenic diet and phenol compounds.
PubMed:The novel pterostilbene derivative ANK-199 induces autophagic cell death through regulating PI3 kinase class III/beclin 1/Atg‑related proteins in cisplatin‑resistant CAR human oral cancer cells.
PubMed:Nanoemulsion for solubilization, stabilization, and in vitro release of pterostilbene for oral delivery.
PubMed:Pterostilbene attenuates lipopolysaccharide-induced learning and memory impairment possibly via inhibiting microglia activation and protecting neuronal injury in mice.
PubMed:Pterostilbene-isothiocyanate conjugate suppresses growth of prostate cancer cells irrespective of androgen receptor status.
PubMed:Investigation of liquid chromatography quadrupole time-of-flight mass spectrometry performance for identification and determination of hydroxylated stilbene antioxidants in wine.
PubMed:Enhanced antitumor efficacy with combined administration of astragalus and pterostilbene for melanoma.
PubMed:In vitro and in vivo activities of pterostilbene against Candida albicans biofilms.
PubMed:Natural potential therapeutic agents of neurodegenerative diseases from the traditional herbal medicine Chinese dragon's blood.
PubMed:Inhibitory effects of stilbenes on the growth of three soybean pathogens in culture.
PubMed:Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators.
PubMed:Urokinase-type plasminogen activator expression and Rac1/WAVE-2/Arp2/3 pathway are blocked by pterostilbene to suppress cell migration and invasion in MDA-MB-231 cells.
PubMed:Pterostilbene as a potential novel telomerase inhibitor: molecular docking studies and its in vitro evaluation.
PubMed:Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2.
PubMed:The stilbenes resveratrol, pterostilbene and piceid affect growth and stress resistance in mammalian cells via a mechanism requiring estrogen receptor beta and the induction of Mn-superoxide dismutase.
PubMed:Nutritional Supplement-5 with a Combination of Proteasome Inhibitors (Resveratrol, Quercetin, δ-Tocotrienol) Modulate Age-Associated Biomarkers and Cardiovascular Lipid Parameters in Human Subjects.
PubMed:Natural stilbenoids isolated from grapevine exhibiting inhibitory effects against HIV-1 integrase and eukaryote MOS1 transposase in vitro activities.
PubMed:Pterostilbene induces accumulation of autophagic vacuoles followed by cell death in HL60 human leukemia cells.
PubMed:Production of pinostilbene compounds by the expression of resveratrol O-methyltransferase genes in Escherichia coli.
PubMed:Characterisation of stilbenes in California almonds (Prunus dulcis) by UHPLC-MS.
PubMed:Role of isothiocyanate conjugate of pterostilbene on the inhibition of MCF-7 cell proliferation and tumor growth in Ehrlich ascitic cell induced tumor bearing mice.
PubMed:The effects of pterostilbene on neutrophil activity in experimental model of arthritis.
PubMed:A combination of pterostilbene with autophagy inhibitors exerts efficient apoptotic characteristics in both chemosensitive and chemoresistant lung cancer cells.
PubMed:Strategies to improve the solubility and stability of stilbene antioxidants: a comparative study between cyclodextrins and bile acids.
PubMed:Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions.
PubMed:Scavenging of hydroxyl radical by resveratrol and related natural stilbenes after hydrogen peroxide attack on DNA.
PubMed:Protective effect of Pterostilbene against free radical mediated oxidative damage.
PubMed:Synergistic induction of human cathelicidin antimicrobial peptide gene expression by vitamin D and stilbenoids.
PubMed:Differences in the glucuronidation of resveratrol and pterostilbene: altered enzyme specificity and potential gender differences.
PubMed:BlueBerry Isolate, Pterostilbene, Functions as a Potential Anticancer Stem Cell Agent in Suppressing Irradiation-Mediated Enrichment of Hepatoma Stem Cells.
PubMed:The molecular basis for the inhibition of phosphodiesterase-4D by three natural resveratrol analogs. Isolation, molecular docking, molecular dynamics simulations, binding free energy, and bioassay.
PubMed:Reporter protein complementation imaging assay to screen and study Nrf2 activators in cells and living animals.
PubMed:Pterostilbene: Biomedical applications.
PubMed:Stilbenes and anthocyanins reduce stress signaling in BV-2 mouse microglia.
PubMed:A review of pterostilbene antioxidant activity and disease modification.
PubMed:Anxiolytic action of pterostilbene: involvement of hippocampal ERK phosphorylation.
PubMed:Pterostilbene exerts antitumor activity via the Notch1 signaling pathway in human lung adenocarcinoma cells.
PubMed:Dehydrodimerization of pterostilbene during electrospray ionization mass spectrometry.
PubMed:Ebselen reduces the toxicity of mechlorethamine in A-431 cells via inhibition of apoptosis.
PubMed:Identification of Plasmopara viticola genes potentially involved in pathogenesis on grapevine suggests new similarities between oomycetes and true fungi.
PubMed:Ebselen analogues reduce 2-chloroethyl ethyl sulphide toxicity in A-431 cells.
PubMed:Resveratrol and related stilbenes: their anti-aging and anti-angiogenic properties.
PubMed:Long-term ethanol exposure-induced hepatocellular carcinoma cell migration and invasion through lysyl oxidase activation are attenuated by combined treatment with pterostilbene and curcumin analogues.
PubMed:Pterostilbene, a bioactive component of blueberries, suppresses the generation of breast cancer stem cells within tumor microenvironment and metastasis via modulating NF-κB/microRNA 448 circuit.
PubMed:Pterostilbene acts through metastasis-associated protein 1 to inhibit tumor growth, progression and metastasis in prostate cancer.
PubMed:Analysis of safety from a human clinical trial with pterostilbene.
PubMed:Pharmacokinetics of pterostilbene in Sprague-Dawley rats: the impacts of aqueous solubility, fasting, dose escalation, and dosing route on bioavailability.
PubMed:Invadopodia-associated proteins blockade as a novel mechanism for 6-shogaol and pterostilbene to reduce breast cancer cell motility and invasion.
PubMed:Pterostilbene and its emerging antineoplastic effects: a prospective treatment option for systemic malignancies.
PubMed:Pterostilbene inhibits dimethylnitrosamine-induced liver fibrosis in rats.
PubMed:Growth inhibitory effect of grape phenolics against wine spoilage yeasts and acetic acid bacteria.
PubMed:Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signaling pathway.
PubMed:The inhibitory effect of pterostilbene on inflammatory responses during the interaction of 3T3-L1 adipocytes and RAW 264.7 macrophages.
PubMed:Pterostilbene induces cell cycle arrest and apoptosis in MOLT4 human leukemia cells.
PubMed:Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
PubMed:Suppression of Nitric Oxide Production and Cardiovascular Risk Factors in Healthy Seniors and Hypercholesterolemic Subjects by a Combination of Polyphenols and Vitamins.
PubMed:Involvement of caspase-3 in stilbene derivatives induced apoptosis of human neutrophils in vitro.
PubMed:Effect of stilbene derivative on superoxide generation and enzyme release from human neutrophils in vitro.
PubMed:Polyphenol derivatives - potential regulators of neutrophil activity.
PubMed:Decreased activity and accelerated apoptosis of neutrophils in the presence of natural polyphenols.
PubMed:Chemopreventive effects of pterostilbene on urethane-induced lung carcinogenesis in mice via the inhibition of EGFR-mediated pathways and the induction of apoptosis and autophagy.
PubMed:Pterostilbene-induced tumor cytotoxicity: a lysosomal membrane permeabilization-dependent mechanism.
PubMed:Pterostilbene ameliorates tumor necrosis factor alpha-induced pancreatitis in vitro.
PubMed:Determination of hydroxylated stilbenes in wine by dispersive liquid-liquid microextraction followed by gas chromatography mass spectrometry.
PubMed:Pterostilbene, a natural small-molecular compound, promotes cytoprotective macroautophagy in vascular endothelial cells.
PubMed:Effect of polyphenols on enniatins-induced cytotoxic effects in mammalian cells.
PubMed:Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice.
PubMed:Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesis.
PubMed:[Simultaneous determination of five active components in resina draconis and its extract by HPLC].
PubMed:Calcofluor white combination antifungal treatments for Trichophyton rubrum and Candida albicans.
PubMed:Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor.
PubMed:Activation of AMPK by pterostilbene suppresses lipogenesis and cell-cycle progression in p53 positive and negative human prostate cancer cells.
PubMed:Comparison of conventional and non conventional methods of extraction of heartwood of Pterocarpus marsupium Roxb.
PubMed:Inhibitory effects of (-)-epigallocatechin-3-gallate and pterostilbene on pancreatic cancer growth in vitro.
PubMed:Pterostilbene induces mitochondrially derived apoptosis in breast cancer cells in vitro.
PubMed:A berry thought-provoking idea: the potential role of plant polyphenols in the treatment of age-related cognitive disorders.
PubMed:Genomic analysis of pterostilbene predicts its antiproliferative effects against pancreatic cancer in vitro and in vivo.
PubMed:Stilbene derivatives promote Ago2-dependent tumour-suppressive microRNA activity.
PubMed:Pterostilbene simultaneously induces apoptosis, cell cycle arrest and cyto-protective autophagy in breast cancer cells.
PubMed:Susceptibility to downy mildew in grape clusters: New microscopical and biochemical insights.
PubMed:Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention.
PubMed:3,5-dibenzyloxy-4'-hydroxystilbene induces early caspase-9 activation during apoptosis in human K562 chronic myelogenous leukemia cells.
PubMed:Long term induction by pterostilbene results in autophagy and cellular differentiation in MCF-7 cells via ROS dependent pathway.
PubMed:Potential chemoprevention activity of pterostilbene by enhancing the detoxifying enzymes in the HT-29 cell line.
PubMed:Pterostilbene and cancer: current review.
PubMed:Inhibitory effects of garcinol and pterostilbene on cell proliferation and adipogenesis in 3T3-L1 cells.
PubMed:Critical factors in the development of tumor-targeted anti-inflammatory nanomedicines.
PubMed:Co-expression of VpROMT gene from Chinese wild Vitis pseudoreticulata with VpSTS in tobacco plants and its effects on the accumulation of pterostilbene.
PubMed:Antifungal activity of resveratrol against Botrytis cinerea is improved using 2-furyl derivatives.
PubMed:Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease.
PubMed:The antiproliferative effects of pterostilbene on breast cancer in vitro are via inhibition of constitutive and leptin-induced Janus kinase/signal transducer and activator of transcription activation.
PubMed:Resveratrol modulates MED28 (Magicin/EG-1) expression and inhibits epidermal growth factor (EGF)-induced migration in MDA-MB-231 human breast cancer cells.
PubMed:Inhibitory effects of resveratrol and pterostilbene on human colon cancer cells: a side-by-side comparison.
PubMed:Pterostilbene protects vascular endothelial cells against oxidized low-density lipoprotein-induced apoptosis in vitro and in vivo.
PubMed:In planta production of the highly potent resveratrol analogue pterostilbene via stilbene synthase and O-methyltransferase co-expression.
PubMed:Resistance to Plasmopara viticola in a grapevine segregating population is associated with stilbenoid accumulation and with specific host transcriptional responses.
PubMed:Pterostilbene suppresses benzo[a]pyrene-induced airway remodeling.
PubMed:Utilization of adjuvant arthritis model for evaluation of new approaches in rheumatoid arthritis therapy focused on regulation of immune processes and oxidative stress.
PubMed:Development of a reversed phase high performance liquid chromatography method based on the use of cyclodextrins as mobile phase additives to determine pterostilbene in blueberries.
PubMed:Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway.
PubMed:[Chemical principles and bioactivities of blueberry].
PubMed:Identification of reference genes suitable for qRT-PCR in grapevine and application for the study of the expression of genes involved in pterostilbene synthesis.
PubMed:Biological activity of peanut (Arachis hypogaea) phytoalexins and selected natural and synthetic Stilbenoids.
PubMed:Improving solubility and chemical stability of natural compounds for medicinal use by incorporation into liposomes.
PubMed:Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression.
PubMed:The effectiveness of stilbenes in resistant Vitaceae: ultrastructural and biochemical events during Plasmopara viticola infection process.
PubMed:In vivo effect of pinosylvin and pterostilbene in the animal model of adjuvant arthritis.
PubMed:Molecular targets of the natural antioxidant pterostilbene: effect on protein kinase C, caspase-3 and apoptosis in human neutrophils in vitro.
PubMed:Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats.
PubMed:Kinetic mechanism and product characterization of the enzymatic peroxidation of pterostilbene as model of the detoxification process of stilbene-type phytoalexins.
PubMed:Pterostilbene and tamoxifen show an additive effect against breast cancer in vitro.
PubMed:Pterostilbene. Monograph.
PubMed:Pterostilbene inhibits colorectal aberrant crypt foci (ACF) and colon carcinogenesis via suppression of multiple signal transduction pathways in azoxymethane-treated mice.
PubMed:[Chemopreventive and chemotherapeutic effect of trans-resveratrol and its analogues in cancer].
PubMed:Pterostilbene induces autophagy and apoptosis in sensitive and chemoresistant human bladder cancer cells.
PubMed:Structural identification of mouse urinary metabolites of pterostilbene using liquid chromatography/tandem mass spectrometry.
PubMed:Use of reversed phase high pressure liquid chromatography for the physicochemical and thermodynamic characterization of oxyresveratrol/beta-cyclodextrin complexes.
PubMed:Pterostilbene, a natural dimethylated analog of resveratrol, inhibits rat aortic vascular smooth muscle cell proliferation by blocking Akt-dependent pathway.
PubMed:Cytotoxic and antioxidant effects of methoxylated stilbene analogues on HepG2 hepatoma and Chang liver cells: Implications for structure activity relationship.
PubMed:The assay of pterostilbene in spiked matrices by liquid chromatography tandem mass spectrometry and isotope dilution method.
PubMed:In vitro evaluation of the cytotoxic, anti-proliferative and anti-oxidant properties of pterostilbene isolated from Pterocarpus marsupium.
PubMed:Pterostilbene inhibits pancreatic cancer in vitro.
PubMed:Antioxidant effect of trans-resveratrol, pterostilbene, quercetin and their combinations in human erythrocytes in vitro.
PubMed:Stilbene glucoside from Polygonum multiflorum Thunb.: a novel natural inhibitor of advanced glycation end product formation by trapping of methylglyoxal.
PubMed:Differential effects of resveratrol and its naturally occurring methylether analogs on cell cycle and apoptosis in human androgen-responsive LNCaP cancer cells.
PubMed:Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats.
PubMed:Determination and imaging of metabolites from Vitis vinifera leaves by laser desorption/ionisation time-of-flight mass spectrometry.
PubMed:Pterostilbene inhibits breast cancer in vitro through mitochondrial depolarization and induction of caspase-dependent apoptosis.
PubMed:Pterostilbene inhibits lung cancer through induction of apoptosis.
PubMed:Effects of pterostilbene on melanoma alone and in synergy with inositol hexaphosphate.
PubMed:Complexation of pinosylvin, an analogue of resveratrol with high antifungal and antimicrobial activity, by different types of cyclodextrins.
PubMed:Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation.
PubMed:Anti-inflammatory action of pterostilbene is mediated through the p38 mitogen-activated protein kinase pathway in colon cancer cells.
PubMed:Determination of pterostilbene in rat plasma by a simple HPLC-UV method and its application in pre-clinical pharmacokinetic study.
PubMed:Simultaneous quantification of five major constituents in stems of Dracaena plants and related medicinal preparations from China and Vietnam by HPLC-DAD.
PubMed:Physicochemical study of the complexation of pterostilbene by natural and modified cyclodextrins.
PubMed:Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells.
PubMed:Induction of defence mechanisms in grapevine leaves by emodin- and anthraquinone-rich plant extracts and their conferred resistance to downy mildew.
PubMed:Dietary administration of high doses of pterostilbene and quercetin to mice is not toxic.
PubMed:Pterostilbene from Vitis coignetiae protect H2O2-induced inhibition of gap junctional intercellular communication in rat liver cell line.
PubMed:Structure-efficiency relationship in derivatives of stilbene. Comparison of resveratrol, pinosylvin and pterostilbene.
PubMed:Polyphenolic composition of roots and petioles of Rheum rhaponticum L.
PubMed:Cellular and behavioral effects of stilbene resveratrol analogues: implications for reducing the deleterious effects of aging.
PubMed:Characterization of a Pterostilbene Dehydrodimer Produced by Laccase of Botrytis cinerea.
PubMed:Botrytis cinerea Infection in Grape Flowers: Defense Reaction, Latency, and Disease Expression.
PubMed:Natural polyphenols facilitate elimination of HT-29 colorectal cancer xenografts by chemoradiotherapy: a Bcl-2- and superoxide dismutase 2-dependent mechanism.
PubMed:Biological/chemopreventive activity of stilbenes and their effect on colon cancer.
PubMed:A stress-inducible resveratrol O-methyltransferase involved in the biosynthesis of pterostilbene in grapevine.
PubMed:Pharmacometrics of stilbenes: seguing towards the clinic.
PubMed:Pterostilbene suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages.
PubMed:Pterostilbene is equally potent as resveratrol in inhibiting 12-O-tetradecanoylphorbol-13-acetate activated NFkappaB, AP-1, COX-2, and iNOS in mouse epidermis.
PubMed:In vitro evaluation of the cytotoxic and anti-proliferative properties of resveratrol and several of its analogs.
PubMed:Effects of resveratrol and its derivatives on lipopolysaccharide-induced microglial activation and their structure-activity relationships.
PubMed:Identification of molecular pathways affected by pterostilbene, a natural dimethylether analog of resveratrol.
PubMed:Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARalpha.
PubMed:Pharmacometrics of pterostilbene: preclinical pharmacokinetics and metabolism, anticancer, antiinflammatory, antioxidant and analgesic activity.
PubMed:Pterostilbene induces apoptosis and cell cycle arrest in human gastric carcinoma cells.
PubMed:Production and secretion of resveratrol in hairy root cultures of peanut.
PubMed:Inhibition of human recombinant cytochromes P450 CYP1A1 and CYP1B1 by trans-resveratrol methyl ethers.
PubMed:Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci formation in the azoxymethane-induced colon carcinogenesis model in rats.
PubMed:Nitric oxide mediates natural polyphenol-induced Bcl-2 down-regulation and activation of cell death in metastatic B16 melanoma.
PubMed:The antioxidant role of pterostilbene in streptozotocin-nicotinamide-induced type 2 diabetes mellitus in Wistar rats.
PubMed:High-performance liquid chromatographic analysis of pterostilbene in biological fluids using fluorescence detection.
PubMed:Effect of natural analogues of trans-resveratrol on cytochromes P4501A2 and 2E1 catalytic activities.
PubMed:Effect of pterostilbene on hepatic key enzymes of glucose metabolism in streptozotocin- and nicotinamide-induced diabetic rats.
PubMed:Pterocarpus marsupium extract (Vijayasar) prevented the alteration in metabolic patterns induced in the normal rat by feeding an adequate diet containing fructose as sole carbohydrate.
PubMed:Selective COX-2 inhibition by a Pterocarpus marsupium extract characterized by pterostilbene, and its activity in healthy human volunteers.
PubMed:Pterostilbene and 3'-hydroxypterostilbene are effective apoptosis-inducing agents in MDR and BCR-ABL-expressing leukemia cells.
PubMed:Pterostilbene, a new agonist for the peroxisome proliferator-activated receptor alpha-isoform, lowers plasma lipoproteins and cholesterol in hypercholesterolemic hamsters.
PubMed:Association between pterostilbene and quercetin inhibits metastatic activity of B16 melanoma.
PubMed:Antioxidant activity of hydroxystilbene derivatives in homogeneous solution.
PubMed:Resveratrol, pterostilbene, and piceatannol in vaccinium berries.
PubMed:Chalconoid and stilbenoid glycosides from Guibourtia tessmanii.
PubMed:Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol.
PubMed:[Constituents in petroleum ether and ethyl acetate extract fractions of Dracaena cochinensis (Lour.) S.C. Chen].
PubMed:Stilbene content of mature Vitis vinifera berries in response to UV-C elicitation.
PubMed:Occurrence of resveratrol and pterostilbene in age-old darakchasava, an ayurvedic medicine from India.
PubMed:Changes in the phytoalexin content of various Vitis spp. in response to ultraviolet C elicitation.
PubMed:Antihyperglycemic activity of phenolics from Pterocarpus marsupium.
 
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