EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

diflufenican
3-pyridinecarboxamide, N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]-

Supplier Sponsors

CAS Number: 83164-33-4Picture of molecule3D/inchi
FDA UNII: 3T8D1VDO6K
Nikkaji Web:J246.562K
Beilstein Number:4212494
MDL:MFCD01311804
XlogP3-AA:4.60 (est)
Molecular Weight:394.30108600
Formula:C19 H11 F5 N2 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 160.00 °C. @ 760.00 mm Hg
Boiling Point: 376.17 °C. @ 760.00 mm Hg (est)
Flash Point: 358.00 °F. TCC ( 181.30 °C. ) (est)
logP (o/w): 4.900
Soluble in:
 water, 0.05 mg/L @ 25 °C (exp)
 water, 0.2171 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Glentham Life Sciences
Diflufenican
Santa Cruz Biotechnology
For experimental / research use only.
Diflufenican
Sigma-Aldrich
For experimental / research use only.
Diflufenican PESTANAL®, analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 > 1000 mg/kg
Pesticide Manual. Vol. 9, Pg. 283, 1991.

oral-rabbit LD50 5000 mg/kg
Defense des Vegetaux. Vol. 41(247), Pg. 21, 1987.

oral-rat LD50 2000 mg/kg
Defense des Vegetaux. Vol. 41(247), Pg. 21, 1987.

Dermal Toxicity:
skin-rat LD50 2000 mg/kg
Defense des Vegetaux. Vol. 41(247), Pg. 21, 1987.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
herbicides / pesticides
Recommendation for diflufenican usage levels up to:
 not for fragrance use.
 
Recommendation for diflufenican flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Reasoned opinion on the review of the existing maximum residue levels (MRLs) for diflufenican according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf

Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf

Protocol for the evaluation of data concerning the necessity of the application of herbicide active substances to control a serious danger to plant health which cannot be contained by other available means, including non-chemical methods
View page or View pdf

Modification of the existing maximum residue level for diflufenican in olives for oil production
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :91735
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide
Chemidplus:0083164334
 
References:
 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):91735
Pubchem (sid):135049039
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C18549
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 brodal
 diflufenicanil
2',4'-difluoro-2-(a,a,a-trifluoro-m-tolyloxy)nicotinanilide
N-(2,4-difluorophenyl)-2-(3-(trifluoromethyl)phenoxy)-3-pyridinecarboxamide
N-(2,4-difluorophenyl)-2-(3-(trifluoromethyl)phenoxy)nicotinamide
N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]-3-pyridinecarboxamide
N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]nicotinamide
N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide
N-(2,4-difluorophenyl){2-[3-(trifluoromethyl)phenoxy](3-pyridyl)}carboxamide
 kwarc
3-pyridinecarboxamide, N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]-
 

Articles:

PubMed:Identification of the first glyphosate-resistant wild radish (Raphanus raphanistrum L.) populations.
PubMed:Comparison of solid phase- and liquid/liquid-extraction for the purification of hair extract prior to multi-class pesticides analysis.
PubMed:Single drop microextraction and gas chromatography-mass spectrometry for the determination of diflufenican, mepanipyrim, fipronil, and pretilachlor in water samples.
PubMed:Radical-based regioselective C-H functionalization of electron-deficient heteroarenes: scope, tunability, and predictability.
PubMed:Accumulation and half-lives of 13 pesticides in muscle tissue of freshwater fishes through food exposure.
PubMed:Pesticide pressure and fish farming in barrage pond in Northeastern France. Part II: residues of 13 pesticides in water, sediments, edible fish and their relationships.
PubMed:Aquatic toxicity tests with substances that are poorly soluble in water and consequences for environmental risk assessment.
PubMed:Pesticide pressure and fish farming in barrage pond in northeastern France. Part III: how management can affect pesticide profiles in edible fish?
PubMed:Determination of farm workers' exposure to pesticides by hair analysis.
PubMed:Phyt'Eaux Cités: application and validation of a programme to reduce surface water contamination with urban pesticides.
PubMed:Simultaneous analysis of pesticides from different chemical classes by using a derivatisation step and gas chromatography-mass spectrometry.
PubMed:Multiresidue method for the determination of 13 pesticides in three environmental matrices: water, sediments and fish muscle.
PubMed:Determination of acetanilide herbicides in cereal crops using accelerated solvent extraction, solid-phase extraction and gas chromatography-electron capture detector.
PubMed:Multiresidue method to quantify pesticides in fish muscle by QuEChERS-based extraction and LC-MS/MS.
PubMed:Use of metabolic control analysis to give quantitative information on control of lipid biosynthesis in the important oil crop, Elaeis guineensis (oilpalm).
PubMed:Utility of delayed fluorescence as endpoint for rapid estimation of effect concentration on the green alga Pseudokirchneriella subcapitata.
PubMed:Evolution of soil biological properties after addition of glyphosate, diflufenican and glyphosate+diflufenican herbicides.
PubMed:CRA-W's committee of intervention: analyse of catchments polluted with pesticides.
PubMed:Treatment influence on herbicide resistance level of Belgian Alopecurus myosuroides populations (black-grass).
PubMed:Comparison of annual dry and wet deposition fluxes of selected pesticides in Strasbourg, France.
PubMed:Synthesis and herbicidal activities of novel 3-N-substituted amino-6-methyl-4-(3-trifluoromethylphenyl)pyridazine derivatives.
PubMed:Possibilities of chemical weed control in Lupinus albus and Lupinus luteus-screening of herbicides.
PubMed:Characterization of a higher plant herbicide-resistant phytoene desaturase and its use as a selectable marker.
PubMed:Comparison of the efficiencies of different types of adsorbents at trapping currently used pesticides in the gaseous phase using the technique of high-volume sampling.
PubMed:Investigation of various physicochemical and environmental parameter influence on pesticide sorption to ditch bed substratum by means of experimental design.
PubMed:Spatial variation in the degradation rate of the pesticides isoproturon, azoxystrobin and diflufenican in soil and its relationship with chemical and microbial properties.
PubMed:Elimination of pesticides in olive oil by refining using bleaching and deodorization.
PubMed:Rainfastness and adsorption of herbicides on hard surfaces.
PubMed:Field experiences with recent ALS-inhibitors on herbicide resistant blackgrass (Alopecurus myosuroides Huds.).
PubMed:Soil surface structure effect on isoproturon and diflufenican loss in runoff.
PubMed:Soil dissipation of diuron, chlorotoluron, simazine, propyzamide, and diflufenican herbicides after repeated applications in fruit tree orchards.
PubMed:Evaluation of surface- and ground-water pollution due to herbicides in agricultural areas of Zamora and Salamanca (Spain).
PubMed:Analytical methods for the determination of isoproturon and diflufenican residues in runoff and soil.
PubMed:The effect of diflufenican on lipid metabolism in plants.
 
Notes:
None found
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