EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

sodium nigericin
nigericin, monosodium salt

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CAS Number: 28643-80-3Picture of molecule3D/inchi
FDA UNII: DGN38HI976
Beilstein Number:3892398
MDL:MFCD00036825
Molecular Weight:746.95495928
Formula:C40 H67 Na O11
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Appearance:white powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 779.90 °C. @ 760.00 mm Hg (est)
Flash Point: 440.00 °F. TCC ( 226.90 °C. ) (est)
logP (o/w): 4.817 (est)
Soluble in:
 water, 0.01632 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Nigericin sodium >98% by HPLC
Odor: characteristic
Use: The atypical salt of nigericin
Carbosynth
For experimental / research use only.
Nigericin sodium salt
Glentham Life Sciences
Nigericin sodium salt
Sigma-Aldrich: Sigma
For experimental / research use only.
Nigericin sodium salt ≥98% (TLC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 48 mg/kg
Journal of Antibiotics. Vol. 30, Pg. 77-5, 1977.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for sodium nigericin usage levels up to:
 not for fragrance use.
 
Recommendation for sodium nigericin flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

EPI System: View
AIDS Citations:Search
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Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23681158
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
Chemidplus:0028643803
RTECS:QT6840000 for cas# 28643-80-3
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):23681158
Pubchem (sid):134998025
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 nigericin sodium
 nigericin sodium salt
 nigericin, monosodium salt
 
 
Notes:
a polyether antibiotic which affects ion transport and atpase activity in mitochondria. it is produced by streptomyces hygroscopicus. (from merck index, 11th ed)
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