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scopolamine hydrobromide
benzeneacetic acid, a-(hydroxymethyl)-, (1S,2R,4S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, (aS)-, hydrobromide (1:1)

Supplier Sponsors

CAS Number: 6533-68-2Picture of molecule3D/inchi
Other(deleted CASRN):6791-70-4
FDA UNII: 451IFR0GXB
Beilstein Number:6100669
MDL:MFCD00150066
Molecular Weight:384.27014000
Formula:C17 H22 Br N O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Appearance:white crystals (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 487.70 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000000 mmHg @ 25.00 °C. (est)
Flash Point: 480.00 °F. TCC ( 248.80 °C. ) (est)
logP (o/w): 0.760 (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Scopolamine hydrobromide trihydrate
Odor: characteristic
Use: Scopolamine is a competitive muscarinic acetylcholine receptor antagonist with IC50 value of 55.3 nM.
Carbosynth
For experimental / research use only.
Scopolamine hydrobromide trihydrate - USP
Changsha Organic Herb
Henbane Extract
Glentham Life Sciences
(-)-Scopolamine hydrobromide trihydrate
Santa Cruz Biotechnology
For experimental / research use only.
Scopolamine hydrobromide trihydrate
Shaanxi Y-Herb Biotechnology
Datura Flower Extract Monomer Powder Scopolamine Hydrobromide Powder CAS 114-49-8
Sigma-Aldrich: Sigma
For experimental / research use only.
(-)-Scopolamine hydrobromide trihydrate ≥98% (HPLC), powder
TCI AMERICA
For experimental / research use only.
Scopolamine Hydrobromide Trihydrate >98.0%(HPLC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
subcutaneous-mouse LD50 1413 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 17, Pg. 60, 1970.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for scopolamine hydrobromide usage levels up to:
 not for fragrance use.
 
Recommendation for scopolamine hydrobromide flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on Tropane alkaloids in food and feed
View page or View pdf

ClinicalTrials.gov:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :656679
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
Chemidplus:0006533682
EPA/NOAA CAMEO:hazardous materials
RTECS:YM4730000 for cas# 6533-68-2
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):656679
Pubchem (sid):135019156
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):D02071
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2939.80.0000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 benzeneacetic acid, a-(hydroxymethyl)-, (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, (aS)-, hydrobromide
 benzeneacetic acid, a-(hydroxymethyl)-, (1S,2R,4S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, (aS)-, hydrobromide (1:1)
 hyoscinehydrobromide
(1S,2R,4S,5S,7R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl (2S)-3-hydroxy-2-phenylpropanoate
(1S,2R,4S,5S,7R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl (2S)-3-hydroxy-2-phenylpropanoate hydrobromide
(1S,2R,4S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl (2S)-3-hydroxy-2-phenylpropanoate hydrobromide (1:1)
 scopolamine hydrobromide trihydrate
 

Articles:

PubMed:Chin rub CRs are elicited by flavors associated with apomorphine, scopolamine, methscopolamine, physostigmine and neostigmine.
PubMed:[Simultaneous determination of scopolamine hydrobromide, atropine sulfate, ephedrine hydrochloride and pseudoephedrine hydrochloride in Zhichuanling oral liquid with HPLC].
PubMed:D-cycloserine in prelimbic cortex reverses scopolamine-induced deficits in olfactory memory in rats.
PubMed:Neuromodulatory propensity of Bacopa monniera against scopolamine-induced cytotoxicity in PC12 cells via down-regulation of AChE and up-regulation of BDNF and muscarnic-1 receptor expression.
PubMed:Cognitive-enhancing effects of Rhus verniciflua bark extract and its active flavonoids with neuroprotective and anti-inflammatory activities.
PubMed:Noradrenergic but not cholinergic modulation of olfactory bulb during processing of near threshold concentration stimuli.
PubMed:Lactobacillus pentosus var. plantarum C29 protects scopolamine-induced memory deficit in mice.
PubMed:Acute effects of a low-dose atropine/scopolamine mixture as a food contaminant in human volunteers.
PubMed:Effects of acute administration of nicotinic and muscarinic cholinergic agonists and antagonists on performance in different cost-benefit decision making tasks in rats.
PubMed:Amelioration of scopolamine induced cognitive dysfunction and oxidative stress by Inonotus obliquus - a medicinal mushroom.
PubMed:Prevention of scopolamine-induced memory deficits by schisandrin B, an antioxidant lignan from Schisandra chinensis in mice.
PubMed:A comparison of scopolamine and biperiden as a rodent model for cholinergic cognitive impairment.
PubMed:Arctigenin isolated from the seeds of Arctium lappa ameliorates memory deficits in mice.
PubMed:Transdermal scopolamine for the prevention of postoperative nausea and vomiting: a systematic review and meta-analysis.
PubMed:A novel extended sequence learning task (ESLeT) for rodents: validation and the effects of amphetamine, scopolamine and striatal lesions.
PubMed:Reversal of memory deficits by Coriandrum sativum leaves in mice.
PubMed:Anti-amnesic effect of Chong-Myung-Tang on scopolamine-induced memory impairments in mice.
PubMed:Influence of age on cognition and scopolamine induced memory impairment in rats measured in the radial maze paradigm.
PubMed:Seizures triggered by food intake in antimuscarinic-treated fasted animals: evaluation of the experimental findings in terms of similarities to eating-triggered epilepsy.
PubMed:Ethanol extract and saponin of Platycodon grandiflorum ameliorate scopolamine-induced amnesia in mice.
PubMed:Interactions between morphine, scopolamine and nicotine: schedule-controlled responding in rats.
PubMed:The ameliorating effect of the extract of the flower of Prunella vulgaris var. lilacina on drug-induced memory impairments in mice.
PubMed:Intra-accumbens infusion of a muscarinic antagonist reduces food intake without altering the incentive properties of food-associated cues.
PubMed:Mass intoxication with Datura innoxia--case series and confirmation by analytical toxicology.
PubMed:Different effects of scopolamine and inhibition of prolyl oligopeptidase on mnemonic and motility functions of young and 8- to 9-month-old rats in the radial-arm maze.
PubMed:Scopolamine-induced convulsions in fasted mice after food intake: evaluation of the sedative effect in the suppression of convulsions.
PubMed:Zeatin prevents amyloid beta-induced neurotoxicity and scopolamine-induced cognitive deficits.
PubMed:Scopolamine-induced migraine like headache.
PubMed:Procyanidins extracted from the lotus seedpod ameliorate scopolamine-induced memory impairment in mice.
PubMed:The role of solid food intake in antimuscarinic-induced convulsions in fasted mice.
PubMed:Effect of triterpenoid saponins from Bacopa monniera on scopolamine-induced memory impairment in mice.
PubMed:[A case of food poisoning due to ingestion of eggplant, Solanum melongena, grafted on Devil's trumpet, Datura metel].
PubMed:Muscarinic receptor blockade in ventral hippocampus and prelimbic cortex impairs memory for socially transmitted food preference.
PubMed:Muscarinic transmission in the basolateral amygdala is necessary for the acquisition of socially transmitted food preferences in rats.
PubMed:Scopolamine-induced convulsions in fasted mice after food intake: the effect of duration of food deprivation.
PubMed:Muscarinic receptor antagonism causes a functional alteration in nucleus accumbens mu-opiate-mediated feeding behavior.
PubMed:Effects of chemotherapeutic agents 5-fluorouracil and methotrexate alone and combined in a mouse model of learning and memory.
PubMed:Scopolamine impairs auditory delayed matching-to-sample performance in monkeys.
PubMed:Interactions between neurons in the frontal cortex and hippocampus in cats trained to select reinforcements of different value in conditions of cholinergic deficiency.
PubMed:Aqueous and hydroalcoholic extracts of Black Maca (Lepidium meyenii) improve scopolamine-induced memory impairment in mice.
PubMed:Urinary excretion of dietary contaminants in horses.
PubMed:Is current UK management of oesophageal food bolus obstruction evidence based? An e-mail survey and literature review.
PubMed:Muscarinic cholinergic receptor blockade in the rat prelimbic cortex impairs the social transmission of food preference.
PubMed:Confirmed Datura poisoning in a horse most probably due to D. ferox in contaminated tef hay.
PubMed:[Determination of scopolamine in the poisoning case by GC/MS].
PubMed:Cholinergic basis of memory-strengthening effect of Foeniculum vulgare Linn.
PubMed:The evaluation of antimuscarinic-induced convulsions in fasted rats after food intake.
PubMed:Electroencephalographic characterization of scopolamine-induced convulsions in fasted mice after food intake.
PubMed:Food for thought: honeybee foraging, memory, and acetylcholine.
PubMed:Nardostachys jatamansi improves learning and memory in mice.
PubMed:Blockade of muscarinic acetylcholine receptors in the ventral tegmental area prevents acquisition of food-rewarded operant responding in rats.
PubMed:Striatal muscarinic receptor antagonism reduces 24-h food intake in association with decreased preproenkephalin gene expression.
PubMed:Blockade of muscarinic acetylcholine receptors in the ventral tegmental area disrupts food-related learning in rats.
PubMed:Scopolamine-induced convulsions in fasted mice after food intake: effects of glucose intake, antimuscarinic activity and anticonvulsant drugs.
PubMed:Identification and estimation of the levo isomer in raw materials and finished products containing atropine and/or hyoscyamine.
PubMed:Memory-strengthening activity of Glycyrrhiza glabra in exteroceptive and interoceptive behavioral models.
PubMed:Effect of acidic oligosaccharide sugar chain on scopolamine-induced memory impairment in rats and its related mechanisms.
PubMed:Effects of green tea polyphenol on cognitive and acetylcholinesterase activities.
PubMed:Nucleus accumbens acetylcholine regulates appetitive learning and motivation for food via activation of muscarinic receptors.
PubMed:Improvement of mouse memory by Myristica fragrans seeds.
PubMed:Effect of antioxidant flavanone, naringenin, from Citrus junoson neuroprotection.
PubMed:Hippocampal N-acetyl aspartate levels do not mirror neuronal cell densities in creatine-supplemented epileptic rats.
PubMed:Scopolamine-induced convulsions in fasted mice after food intake: determination of blood glucose levels, [3H]glutamate binding kinetics and antidopaminergic drug effects.
PubMed:Network activity in neurons of the motor and prefrontal areas of the cortex in trained cats in conditions of systemic administration of m-cholinoreceptor blockers.
PubMed:Residential maze as a task for testing rats' maze learning ability: effects of hippocampal lesions and cholinergic receptor antagonists.
PubMed:The effects of psychotomimetics and psychomotor stimulants on two schedules promoting response switching in the rat.
PubMed:Posttraining intra-basolateral amygdala scopolamine impairs food- and amphetamine-induced conditioned place preferences.
PubMed:Behavioral characterization of mice lacking histamine H(3) receptors.
PubMed:Muscarinic cholinergic receptor blockade impairs free fatty acid mobilization during fasting in pigeons (Columba livia).
PubMed:Effects of selected anticholinergics on acoustic startle response in rats.
PubMed:Evidence that mnesic states govern normal and disordered memory.
PubMed:Water maze versus radial maze: differential performance of rats in a spatial delayed match-to-position task and response to scopolamine.
PubMed:Dietary restriction of choline reduces hippocampal acetylcholine release in rats: in vivo microdialysis study.
PubMed:Investigating potential anxiolytic, antidepressant and memory enhancing activity of deprenyl.
PubMed:[Cooperative activity of motor and frontal cortex neurons in trained cats systemically administered M-cholinoreceptor blockers].
PubMed:Substance P and its transglutaminase-synthesized spermine derivative elicit yawning behavior via nitric oxide in rats.
PubMed:The role of muscarinic cholinoceptors in the retrieval of an operant food-related conditioned reflex in cats.
PubMed:The role of the cholinergic system of the sensorimotor cortex of the rat brain in controlling different types of movement.
PubMed:Enterostatin (VPDPR) has anti-analgesic and anti-amnesic activities.
PubMed:Effects of the cannabinoid ligand SR 141716A alone or in combination with delta9-tetrahydrocannabinol or scopolamine on learning in squirrel monkeys.
PubMed:Involvement of the parafascicular nucleus of the thalamus and the cholinoreactive system of the neostriatum in controlling a food-procuring reflex in rats at different stages of learning.
PubMed:[The role of muscarinic cholinoreceptors in the retrieval of the instrumental food conditioned reflex in cats].
PubMed:Behavioral and memory improving effects of mirtazapine in rats.
PubMed:Effects of scopolamine on a novel choice serial reaction time task.
PubMed:Nicotine in an animal model of attention.
PubMed:The NMDA antagonist EAA 494 does not impair working memory in an operant DNMTP task in rats.
PubMed:[The participation of the cholinergic system of the rat sensorimotor cortex in regulating different types of movements].
PubMed:Dose-response curves and time-course effects of selected anticholinergics on locomotor activity in rats.
PubMed:[The participation of the parafascicular thalamic nucleus and of the neostriatal cholinoreactive system in regulating the food-procuring reflex in rats at different stages of learning].
PubMed:The acetylcholinesterase inhibitor, ENA 713 (Exelon), attenuates the working memory impairment induced by scopolamine in an operant DNMTP task in rats.
PubMed:Scopolamine-induced convulsions in food given fasted mice: effects of clonidine and tizanidine.
PubMed:Hepatic blood supply: comparison of optimized dual phase contrast-enhanced three-dimensional MR angiography and digital subtraction angiography.
PubMed:Intra-amygdala infusions of scopolamine impair performance on a conditioned place preference task but not a spatial radial maze task.
PubMed:The effect of hypothalamic peptide YY on hippocampal acetylcholine release in vivo: implications for limbic function in binge-eating behavior.
PubMed:Anxiolytic and memory improving effects of moclobemide.
PubMed:Evidence of GABAergic modulation in melatonin-induced short-term memory deficits and food consumption.
PubMed:Scopolamine-induced impairment in concurrent fixed-interval responding in a radial maze task.
PubMed:Alcohol intake of P rats is regulated by muscarinic receptors in the pedunculopontine nucleus and VTA.
PubMed:Scopolamine impairs spatial working memory in the radial maze: an analysis by error type and arm choice.
PubMed:Scopolamine-induced convulsions in food given fasted mice: effects of physostigmine and MK-801.
PubMed:Postprandial electrogastrographic changes with or without parasympathetic nerve blockade.
PubMed:Effects of microinjection of scopolamine into the neostriatum of rats on performance of a food conditioned reflex at different levels of fixation.
PubMed:NTP Toxicology and Carcinogenesis Studies of Scopolamine Hydrobromide Trihydrate (CAS No. 6533-68-2) in F344 Rats and B6C3F1 Mice (Gavage Studies).
PubMed:Effects of 5-HT1A receptor agonists, partial agonists and a silent antagonist on the performance of the conditioned emotional response test in the rat.
PubMed:Toxicological comparison of a muscarinic agonist given to rats by gavage or in the diet.
PubMed:The sensitivity of the NTP bioassay for carcinogen hazard evaluation can be modulated by dietary restriction.
PubMed:Effects of scopolamine on learning and memory in monkeys.
PubMed:Age-associated impairments in a test of attention: evidence for involvement of cholinergic systems.
PubMed:[Characteristics of the effect of microinjections of scopolamine into the rat neostriatum on the realization of a conditioned food reflex with different degrees of reinforcement].
PubMed:Physostigmine, but not 3,4-diaminopyridine, improves radial maze performance in memory-impaired rats.
PubMed:Scopolamine-physostigmine combination does not substitute for nicotine.
PubMed:The role of the medial prefrontal cortex of rats in short-term memory functioning: further support for involvement of cholinergic, rather than dopaminergic mechanisms.
PubMed:Influence of prefeeding and scopolamine upon performance in a delayed matching-to-position task.
PubMed:Anti-nutritional factors of Datura in feedstuffs.
PubMed:Computer-assisted shock-reinforced Y-maze training: a method for studying spatial alternation behaviour.
PubMed:Estrogen and estrogen-progesterone treatments counteract the effect of scopolamine on reinforced T-maze alternation in female rats.
PubMed:The effects of physostigmine and scopolamine on memory for food caches in the black-capped chickadee.
PubMed:Radial arm maze behavior in mice when a return to the home cage serves as the reinforcer.
PubMed:Toxicity study of the main alkaloids of Datura ferox in broilers.
PubMed:[A method employing housing in a radial maze apparatus for estimating working memory in mice: effects of scopolamine and delay upon maze performance].
PubMed:Impairment of acquisition but not retention of a simple operant discrimination performance in aged Fischer 344 rats.
PubMed:MK-801 impairs recognition memory in rhesus monkeys: comparison with cholinergic drugs.
PubMed:Comparison of the effects of scopolamine and methylscopolamine on the performance of a fixed-ratio discrimination in squirrel monkeys.
PubMed:Neural mechanisms in the responses to amino acid deficiency.
PubMed:Evaluation of response perseveration of rats in the radial arm maze following reinforcing and nonreinforcing drugs.
PubMed:Cholecystokinin receptors and memory: a radial maze study.
PubMed:Attenuation of scopolamine-induced spatial memory deficits in the rat by cholinomimetic and non-cholinomimetic drugs using a novel task in the 12-arm radial maze.
PubMed:Learning behaviour in chronic vitamin E-deficient and -supplemented rats: radial arm maze learning and passive avoidance response.
PubMed:Differential effects of scopolamine on working and reference memory depend upon level of training.
PubMed:Mice housed in a cage with a maze learn the maze without explicit training.
PubMed:Place conditioning reveals the rewarding aspect of social interaction in juvenile rats.
PubMed:Behavioral effects of some diphenyl-substituted antimuscarinics: comparison with cocaine and atropine.
PubMed:[A simple method using a maze task for estimating working memory in mice].
PubMed:Scopolamine impairs delayed matching in an olfactory task in rats.
PubMed:[A simple multiple maze test to estimate learning and memory in mice: application to the effect of scopolamine on learning and memory].
PubMed:The behavioral effects of heptyl physostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents.
PubMed:Drug effects on cognitive function in mice determined by the non-matching to sample task using a 4-arm maze.
PubMed:[Effects of scopolamine upon delayed radial-arm maze performance in rats].
PubMed:[Scopolamine poisoning as a cause of acute paranoid hallucinatory psychoses].
PubMed:Interactions between scopolamine and muscarinic cholinergic agonists or cholinesterase inhibitors on spatial alternation performance in rats.
PubMed:Relationship of the behavioral effects of aprophen, atropine and scopolamine to antagonism of the behavioral effects of physostigmine.
PubMed:Cholinergic blockade in prefrontal cortex and hippocampus disrupts short-term memory in rats.
PubMed:Effects of azaprophen, scopolamine and trihexyphenidyl on schedule-controlled behavior, before and after chronic physostigmine.
PubMed:Assessment of working memory in rats using spatial alternation behavior with variable retention intervals: effects of fixed-ratio size and scopolamine.
PubMed:Scopolamine and methylscopolamine differentially affect fixed-consecutive-number performance of male and female Wistar rats.
PubMed:Idebenone improves learning and memory impairment induced by cholinergic or serotonergic dysfunction in rats.
PubMed:In vitro release profiles of clonidine transdermal therapeutic systems and scopolamine transdermal patches.
PubMed:Physostigmine-insensitive behavioral excitatory effects of atropine in squirrel monkeys.
PubMed:Time-related facilitation and suppression of drinking by muscarinic anticholinergic drugs in water non-deprived rats.
PubMed:Discriminative stimulus properties of physostigmine in rats.
PubMed:Muscarinic antagonist enhances one-trial food-aversion learning in the mollusc Pleurobranchaea.
PubMed:Validation of a radial maze test for assessing learning and memory in rats.
PubMed:Nicotine impairs acquisition of radial maze performance in rats.
PubMed:Cholinergic-dopaminergic interactions in radial-arm maze performance.
PubMed:Effects of scopolamine on repeated acquisition of radial-arm maze performance by rats.
PubMed:A new method for studying working memory by using the three-panel runway apparatus in rats.
PubMed:Effects of selection delays on radial maze performance: acquisition and effects of scopolamine.
PubMed:Microwave--drug interactions in the cholinergic nervous system of the mouse.
PubMed:Potential interactions between GABAb and cholinergic systems: baclofen augments scopolamine-induced performance deficits in the eight-arm radial maze.
PubMed:Pharmacological characterization of the physostigmine stimulus in rats.
PubMed:Characterization of the scopolamine stimulus in rats.
PubMed:Transcallosal evoked potentials in relation to behavior in the rat: effects of atropine, p-chlorophenylalanine, reserpine, scopolamine and trifluoperazine.
PubMed:Studies on desglycinamide arginine vasopressin and scopolamine in a modified/lever-touch autoshaping model of learning/memory in rats.
PubMed:Discriminative stimulus properties of muscarinic agonists.
PubMed:[Effect of thyrotropin-releasing hormone (TRH) and its analog DN-1417 on scopolamine-induced impairment of short-term memory in rats].
PubMed:Motor activity changes and conditioned taste aversions induced by administration of scopolamine in rats: role of the area postrema.
PubMed:Effects of muscarinic receptor antagonism upon two forms of stress-induced analgesia.
PubMed:A system for assessing toxicity of chemicals by continuous monitoring of homecage behaviors.
PubMed:Chronic exercise produces tolerance to muscarinic antagonists in rats.
PubMed:Scopolamine effects on Hamilton search task performance in monkeys.
PubMed:Effects of altered cholinergic function on working and reference memory in the rat.
PubMed:Specific disruption of spatial behaviour in rats by central muscarinic receptor blockade.
PubMed:Contrasting baseline-dependent effects of amphetamine, chlorpromazine and scopolamine on response switching in the pigeon.
PubMed:[Effect of idebenone on scopolamine-induced impairment of short-term memory in rats].
PubMed:Learning and memory deficits after lesions of the nucleus basalis magnocellularis: reversal by physostigmine.
PubMed:Effects of LY150720 (picenadol), a novel mixed-action opioid, on schedule-controlled responding in the squirrel monkey.
PubMed:Differential effects of scopolamine on working and reference memory of rats in the radial maze.
PubMed:Prolonged behavioral effects of early postnatal lead exposure in rhesus monkeys: fixed-interval responding and interactions with scopolamine and pentobarbital.
PubMed:The effects of amphetamine and scopolamine on adjunctive drinking and wheel-running in rats.
PubMed:Effects of anticholinergic drugs on DRL performance of rhesus monkeys.
PubMed:Changes in schedule-controlled response and schedule-induced drinking after cholinergic blockers in rats.
PubMed:Effects of scopolamine on radial maze performance in rats.
PubMed:Effects of scopolamine, pentobarbital, and amphetamine on radial arm maze performance in the rat.
PubMed:[Role of the cholinergic and monoaminergic systems of the brain in dissociated learning].
PubMed:Effects of physostigmine, atropine and scopolamine on behavior maintained by a multiple schedule of food presentation in the mouse.
PubMed:Pentobarbital, promazine, d-amphetamine, and scopolamine effects on behavior under multiple and primed schedules of reinforcement.
PubMed:The effects of d-amphetamine and scopolamine on drinking induced by a multiple schedule.
PubMed:The effects of scopolamine on extinction and spontaneous recovery.
PubMed:The effects of scopolamine on the temporal control of behavior.
PubMed:Effects of anticholinergic and cholinesterase blocking drugs on appetitive behavior under different deprivation conditions.
PubMed:Scopolamine and adjunctive drinking in rats.
PubMed:Scopolamine: effects on fear or defense responses in the rat.
PubMed:Frontal-striatal control of behavioral inhibition in the rat.
PubMed:Comparing the effects of scopolamine on operant and aggressive responses in squirrel monkeys.
PubMed:Separating the effects of response rate and reinforcement frequency in the rate-dependent effects of amphetamine and scopolamine on the schedule-controlled performance of rats and pigeons.
PubMed:Cholinergic and dopaminergic blocking agents modulate water intake elicited by deprivation, hypovolemia, hypertomicity and isoproterenol.
PubMed:[Effect of fentonio on the basal gastric secretion and on the secretion induced by histalog and food in patients with duodenal ulcer. Comparison with hyoscin butyl-bromide effect].
PubMed:Asthmador: a legal hallucinogen.
PubMed:The effects of cholinolytic drugs and cholinesterase blockade on deprivation based activity and appetitive behavior.
PubMed:Effects of intrastriatal injections of scopolamine on appetitive behavior.
PubMed:Conditioning of food aversions by injections of psychoactive drugs.
PubMed:Comparative effects of amphetamine, scopolamine, chlordiazepoxide, and diphenylhydantoin on operant and extinction behavior with brain stimulation and food reward.
PubMed:Indomethacin-induced intestinal lesions in the rat.
PubMed:Generalization by rats of alcohol and atropine stimulus characteristics to other drugs.
PubMed:[The action of scopolamine and aminazine on the electrical activity of the hypothalamus, cortex and the reticular formation of the midbrain in rabbits with a stimulated conditioned food reflex].
PubMed:NOCTURNAL ENURESIS, A TREATMENT REGIMEN FOR GENERAL USE.
PubMed:Anticholinergic drugs and the central control of thirst.
PubMed:Effect of food, alcohol, and hyoscine on body-temperature and reflex responses of men immersed in cold water.
 
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