| PubMed:Osteoclast-inhibiting saikosaponin derivatives from Bupleurum chinense. |
| PubMed:[Structure of secondary saikosaponins in saiko decoction]. |
| PubMed:[Chemical constituents of n-BuOH extract of Comastoma pedunculatum]. |
| PubMed:Large-scale production of saikosaponins through root culturing of Bupleurum falcatum L. using modified airlift reactors. |
| PubMed:[Effect of combined application of zinc, boron and molybdenum on yield and saikosaponin a, saikosaponin d contents of Bupleurum chinense]. |
| PubMed:Saikosaponin D acts against corticosterone-induced apoptosis via regulation of mitochondrial GR translocation and a GR-dependent pathway. |
| PubMed:Attenuation of neuropathic pain by saikosaponin a in a rat model of chronic constriction injury. |
| PubMed:Saikosaponin-d inhibits proliferation of human undifferentiated thyroid carcinoma cells through induction of apoptosis and cell cycle arrest. |
| PubMed:Formulations, hemolytic and pharmacokinetic studies on saikosaponin a and saikosaponin d compound liposomes. |
| PubMed:Saikosaponin-D reduces cisplatin-induced nephrotoxicity by repressing ROS-mediated activation of MAPK and NF-κB signalling pathways. |
| PubMed:Saikosaponin A of Bupleurum chinense (Chaihu) elevates bone morphogenetic protein 4 (BMP-4) during hepatic stellate cell activation. |
| PubMed:Saikosaponin a inhibits RANKL-induced osteoclastogenesis by suppressing NF-κB and MAPK pathways. |
| PubMed:Saikosaponin C inhibits lipopolysaccharide-induced apoptosis by suppressing caspase-3 activation and subsequent degradation of focal adhesion kinase in human umbilical vein endothelial cells. |
| PubMed:Saikosaponin-d protects renal tubular epithelial cell against high glucose induced injury through modulation of SIRT3. |
| PubMed:Saikosaponin-D attenuates heat stress-induced oxidative damage in LLC-PK1 cells by increasing the expression of anti-oxidant enzymes and HSP72. |
| PubMed:Saikosaponin a and saikosaponin d inhibit proliferation and migratory activity of rat HSC-T6 cells. |
| PubMed:Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling. |
| PubMed:Saikosaponin D disrupts platelet-derived growth factor-β receptor/p38 pathway leading to mitochondrial apoptosis in human LO2 hepatocyte cells: a potential mechanism of hepatotoxicity. |
| PubMed:Effects of saikosaponin A on cocaine self-administration in rats. |
| PubMed:[Impact of saikosaponin on absorption and transport of paeoniflorin in Caco-2 cell model]. |
| PubMed:Saikosaponin b2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry. |
| PubMed:Saikosaponin-d affects the differentiation, maturation and function of monocyte-derived dendritic cells. |
| PubMed:Saikosaponin a, an active compound of Radix Bupleuri, attenuates inflammation in hypertrophied 3T3-L1 adipocytes via ERK/NF-κB signaling pathways. |
| PubMed:Robust PLS Prediction Model for Saikosaponin A in Bupleurum chinense DC. Coupled with Granularity-Hybrid Calibration Set. |
| PubMed:Hepatoprotective saikosaponin homologs from Comastoma pedunculatum. |
| PubMed:Saikosaponin-d increases the radiosensitivity of smmc-7721 hepatocellular carcinoma cells by adjusting the g0/g1 and g2/m checkpoints of the cell cycle. |
| PubMed:[Effects of interferon-alpha combined with saikosaponin on serum T lymphocyte subgroups and hepatic cytokines in mice with immune hepatic injury]. |
| PubMed:Saikosaponin a and its epimer saikosaponin d exhibit anti-inflammatory activity by suppressing activation of NF-κB signaling pathway. |
| PubMed:Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells. |
| PubMed:Saikosaponin-d inhibits β-conglycinin induced activation of rat basophilic leukemia-2H3 cells. |
| PubMed:Saikosaponin D isolated from Bupleurum falcatum inhibits selectin-mediated cell adhesion. |
| PubMed:Saikosaponin A mediates the inflammatory response by inhibiting the MAPK and NF-κB pathways in LPS-stimulated RAW 264.7 cells. |
| PubMed:Effect of corchorusin-D, a saikosaponin like compound, on B16F10 melanoma cells (in vitro and in vivo). |
| PubMed:Multiscale study on the interaction mechanism between ginsenoside biosurfactant and saikosaponin a. |
| PubMed:Osteoclast-inhibiting saikosaponin derivatives from Bupleurum chinense. |
| PubMed:Metabolism of saikosaponin a in rats: diverse oxidations on the aglycone moiety in liver and intestine in addition to hydrolysis of glycosidic bonds. |
| PubMed:Saikosaponin-D enhances radiosensitivity of hepatoma cells under hypoxic conditions by inhibiting hypoxia-inducible factor-1α. |
| PubMed:Putative genes involved in saikosaponin biosynthesis in bupleurum species. |
| PubMed:Effect of saikosaponin A on maintenance of intravenous morphine self-administration. |
| PubMed:Solubilization of saikosaponin a by ginsenoside Ro biosurfactant in aqueous solution: mesoscopic simulation. |
| PubMed:Effects of saikosaponin-d on syndecan-2, matrix metalloproteinases and tissue inhibitor of metalloproteinases-2 in rats with hepatocellular carcinoma. |
| PubMed:["Dose-toxicity" relationship study on rat's chronic hepatoxicity of refined products of saikosaponin by alcohol elution]. |
| PubMed:Saikosaponin-d Enhances the Anticancer Potency of TNF-α via Overcoming Its Undesirable Response of Activating NF-Kappa B Signalling in Cancer Cells. |
| PubMed:Saikosaponin a Enhances Transient Inactivating Potassium Current in Rat Hippocampal CA1 Neurons. |
| PubMed:[Quality inspection of commercial Bupluri Radix samples in Guangzhou: an ELISA for determining saikosaponin A content using anti-saikosaponin A monoclonal antibody]. |
| PubMed:Chemopreventive effect of saikosaponin-d on diethylinitrosamine-induced hepatocarcinogenesis: involvement of CCAAT/enhancer binding protein β and cyclooxygenase-2. |
| PubMed:Saikosaponin a mediates the anticonvulsant properties in the HNC models of AE and SE by inhibiting NMDA receptor current and persistent sodium current. |
| PubMed:Curcumin and saikosaponin a inhibit chemical-induced liver inflammation and fibrosis in rats. |
| PubMed:Separation of triterpenoid saponins from the root of Bupleurum falcatum by counter current chromatography: the relationship between the partition coefficients and solvent system composition. |
| PubMed:Inactivation of cystein-aspartic acid protease (caspase)-1 by saikosaponin A. |
| PubMed:Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. |
| PubMed:Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis. |
| PubMed:[Differences of saikosaponin contents in Bupleurum chinense from habitats in Dongling Mountain & Wuling Mountain of Beijing]. |
| PubMed:[Therapeutic effects and mechanism of saikosaponin-d in mice with bleomycin-induced pulmonary fibrosis]. |
| PubMed:Estrogen-like activities of saikosaponin-d in vitro: a pilot study. |
| PubMed:Species discrimination of Radix Bupleuri through the simultaneous determination of ten saikosaponins by high performance liquid chromatography with evaporative light scattering detection and electrospray ionization mass spectrometry. |
| PubMed:Corchorusin-D, a saikosaponin-like compound isolated from Corchorus acutangulus Lam., targets mitochondrial apoptotic pathways in leukemic cell lines (HL-60 and U937). |
| PubMed:Localization and dynamic change of saikosaponin in root of Bupleurum chinense. |
| PubMed:Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponins. |
| PubMed:[Estrogen-like effects of saikosaponin-d in mice]. |
| PubMed:New triterpenoid saponins from the aerial parts of Comastomapedunculatum. |
| PubMed:[Simultaneous determination of nine effective components in jiaweizuojin pills by ultra performance liquid chromatography with tandem mass spectrometry]. |
| PubMed:Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats. |
| PubMed:[A new saikosaponin from Bupleurum Chinese DC]. |
| PubMed:Effect of saikosaponin, a triterpene saponin, on apoptosis in lymphocytes: association with c-myc, p53, and bcl-2 mRNA. |
| PubMed:Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract. |
| PubMed:Saireito and saikosaponin D prevent urinary protein excretion via glucocorticoid receptor in adrenalectomized WKY rats with heterologous-phase anti-GBM nephritis. |
| PubMed:Saikosaponin C induces endothelial cells growth, migration and capillary tube formation. |
| PubMed:Determination of saikosaponin derivatives in Radix bupleuri and in pharmaceuticals of the chinese multiherb remedy xiaochaihu-tang using liquid chromatographic tandem mass spectrometry. |
| PubMed:Inactivation of measles virus and herpes simplex virus by saikosaponin d. |
| PubMed:Protective effect of saikosaponin A, saikosaponin D and saikogenin D against Pseudomonas aeruginosa infection in mice. |
| PubMed:[Angiogenesis inhibitory effect of saikosaponin-d on chicken embryo]. |
| PubMed:Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation. |
| PubMed:Involvement of p53, nuclear factor kappaB and Fas/Fas ligand in induction of apoptosis and cell cycle arrest by saikosaponin d in human hepatoma cell lines. |
| PubMed:The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cells. |
| PubMed:Inhibition of platelet activation and endothelial cell injury by flavan-3-ol and saikosaponin compounds. |
| PubMed:ERK signaling pathway is involved in p15INK4b/p16INK4a expression and HepG2 growth inhibition triggered by TPA and Saikosaponin a. |
| PubMed:Effect of saikosaponin on the immune responses in mice. |
| PubMed:A high-performance liquid chromatographic method for saikosaponin a quantification in rat plasma. |
| PubMed:[A new saikosaponin from Bupleurum chinense DC]. |
| PubMed:Involvement of p-15(INK4b) and p-16(INK4a) gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells. |
| PubMed:Saikosaponin v-1 from roots of Bupleurum chinense DC. |
| PubMed:Upregulation of isoprenoid pathway genes during enhanced saikosaponin biosynthesis in the hairy roots of Bupleurum falcatum. |
| PubMed:Antagonism of saikosaponin-induced prostaglandin E2 release by baicalein in C6 rat glioma cells. |
| PubMed:ELISA for the determination of saikosaponin a, an active component of Bupleuri Radix. |
| PubMed:Effects of saikosaponin metabolites on the hemolysis of red blood cells and their adsorbability on the cell membrane. |
| PubMed:Analysis of saikosaponins in rat plasma by anionic adducts-based liquid chromatography tandem mass spectrometry method. |
| PubMed:Activation of murine peritoneal macrophages by saikosaponin a, saikosaponin d and saikogenin d. |
| PubMed:[Pharmacological studies on a prescription containing Bupleuri Radix (IV). Effects of saikosaponin on the anti-inflammatory action of glucocorticoid]. |
| PubMed:Saikosaponin-d inhibits T cell activation through the modulation of PKCtheta, JNK, and NF-kappaB transcription factor. |
| PubMed:Pharmacological effects of oral saikosaponin a may differ depending on conditions of the gastrointestinal tract. |
| PubMed:Effects of saikosaponin-d on aminonucleoside nephrosis in rats. |
| PubMed:Protective effect of saikosaponin-d isolated from Bupleurum falcatum L. on CCl4-induced liver injury in the rat. |
| PubMed:Anthelmintic activity of saikosaponins a and d from radix bupleuri against Dactylogyrus spp. infecting goldfish. |
| PubMed:Large-scale production of saikosaponins through root culturing of Bupleurum falcatum L. using modified airlift reactors. |
| PubMed:Saikosaponin homologues from Clinopodium spp. The structures of clinoposaponins XII-XX. |
| PubMed:Studies on the agronomic characteristics, yield, and saikosaponin content of two Bupleurum species in Taiwan. |
| PubMed:Development of an assay system for saikosaponin a using anti-saikosaponin a monoclonal antibodies. |
| PubMed:Saikosaponin-A induces apoptotic mechanism in human breast MDA-MB-231 and MCF-7 cancer cells. |
| PubMed:Saikosaponin homologues from Verbascum spp. The structures of mulleinsaponins I-VII. |
| PubMed:Effects of saikosaponin-d on enhanced CCl4-hepatotoxicity by phenobarbitone. |
| PubMed:[Inhibitory effects of saikosaponin a on rat hippocampal astrocyte activation in vitro]. |
| PubMed:Metabolism of saikosaponin c and naringin by human intestinal bacteria. |
| PubMed:Effects of saikosaponin-d on the functions and morphology of macrophages. |
| PubMed:Mechanism of saikosaponin-d in the regulation of rat mesangial cell proliferation and synthesis of extracellular matrix proteins. |
| PubMed:Comparison between the effects of crude saikosaponin and 16, 16-dimethyl prostaglandin E2 on tannic acid-induced gastric mucosal damage in rats. |
| PubMed:The effects of saikosaponin on macrophage functions and lymphocyte proliferation. |
| PubMed:[Dynamic variation of saikosaponin contents]. |
| PubMed:A distinct characteristic of the quiescent state of human dermal fibroblasts in contracted collagen gel as revealed by no response to epidermal growth factor alone, but a positive growth response to a combination of the growth factor and saikosaponin b1. |
| PubMed:Metabolic fingerprinting by 1HNMR for discrimination of the two species used as Radix Bupleuri. |
| PubMed:Chemical and Physical Methods to Analyze a Multicomponent Traditional Chinese Herbal Prescription Using LC-MS/MS, Electron Microscope, and Congo Red Staining. |
| PubMed:[Study on dynamic accumulation of index components from Bupleurum chinense in various collecting periods]. |
| PubMed:[Effect of saikosaponin alpha on experimental epilepsy in rats]. |
| PubMed:Saikosaponin-d attenuates the development of liver fibrosis by preventing hepatocyte injury. |
| PubMed:[Effect of saikosaponin-d on rat's glomerular mesangial cell proliferation and extracellular matrix hyperplasia in vitro]. |
| PubMed:Cholesteryl hemisuccinate as a membrane stabilizer in dipalmitoylphosphatidylcholine liposomes containing saikosaponin-d. |
| PubMed:Characteristics and mechanism of enzyme secretion and increase in [Ca2+]i in Saikosaponin(I) stimulated rat pancreatic acinar cells. |
| PubMed:[Effect of Saikosaponin-d on up-regulating GR mRNA expression and inhibiting cell growth in human leukemia cells]. |
| PubMed:Inhibitory role of GDP on saikosaponin (I) stimulated enzymes secretion and rising of [Ca2+]i in rat pancreatic acini. |
| PubMed:The effects of saikosaponin-d on yeast phagocytosis and degradation in peritoneal macrophages: related increase in Fc receptor expression and altered cytoplasmic organization. |
| PubMed:Inhibitory effects of saikosaponin-d on CCl4-induced hepatic fibrogenesis in rats. |
| PubMed:[Cholesteryl hemisuccinate as liposomal membrane stabilizer and its use in the preparation of saikosaponin-D liposomes]. |
| PubMed:Therapeutic mechanism of Saikosaponin-d in anti-Thy1 mAb 1-22-3-induced rat model of glomerulonephritis. |
| PubMed:Effect of saikosaponin-A, a triterpenoid glycoside, isolated from Bupleurum falcatum on experimental allergic asthma. |
| PubMed:[Saikosaponin-d up-regulates GR mRNA expression and induces apoptosis in HL-60 cells]. |
| PubMed:Production of antibody against saikosaponin a, an active component of bupleuri radix. |
| PubMed:Saikosaponin b2 induces differentiation without growth inhibition in cultured B16 melanoma cells. |
| PubMed:Metabolism and pharmacokinetics of orally administered saikosaponin b1 in conventional, germ-free and Eubacterium sp. A-44-infected gnotobiote rats. |
| PubMed:Saikosaponin b2-induced apoptosis of cultured B16 melanoma cell line through down-regulation of PKC activity. |
| PubMed:Central administration of saikosaponin-d increases corticotropin-releasing factor mRNA levels in the rat hypothalamus. |
| PubMed:Cell type-oriented differential modulatory actions of saikosaponin-d on growth responses and DNA fragmentation of lymphocytes triggered by receptor-mediated and receptor-bypassed pathways. |
| PubMed:Saikosaponin A-induced cell death of a human hepatoma cell line (HuH-7): the significance of the 'sub-G1 peak' in a DNA histogram. |
| PubMed:Characterization of the immunoregulatory action of saikosaponin-d. |
| PubMed:Scrophulasaponins II-IV, new saikosaponin homologs from Scrophularia kakudensis FRANCH. |
| PubMed:Effect of saikosaponin derivatives upon the immune response against T-dependent and T-independent antigens in mice. |
| PubMed:Effect of saikosaponins and extracts of vinegar-baked Bupleuri Radix on the activity of β-glucuronidase. |
| PubMed:Effects of SSd combined with radiation on inhibiting SMMC-7721 hepatoma cell growth. |
| PubMed:An investigation of the immune suppression induced by some saikosaponin derivatives. |
| PubMed:Quantitative analysis of the metabolites of saikosaponin a using high-performance liquid chromatography. |
| PubMed:[Experimental study of saikosaponin-D (SSd) on lipid peroxidation of hepatic fibrosis on rat]. |
| PubMed:[Progress in research on antitumor activity of saikosaponin and its mechanism]. |
| PubMed:Antiproliferative constituents from Umbelliferae plants VI. New ursane-type saikosaponin analogs from the fruits of Bupleurum rotundifolium. |
| PubMed:Effect of chronic treatment with saikosaponin d and dexamethasone on responsiveness of pituitary and adrenal cortex and adrenal weight in rats. |
| PubMed:Chronic effect of saikosaponin on adrenal and thymus growth in normal and dexamethasone-treated rats. |
| PubMed:Interaction of saponin of bupleuri radix with ginseng saponin: solubilization of saikosaponin-a with chikusetsusaponin V (= ginsenoside-Ro). |
| PubMed:[Comparison on saikosaponin levels in the root of Bupleurum chinense of various sizes]. |
| PubMed:Stimulation of the pituitary-adrenocortical axis by saikosaponin of Bupleuri radix. |
| PubMed:Autophagic effects of Chaihu (dried roots of Bupleurum Chinense DC or Bupleurum scorzoneraefolium WILD). |
| PubMed:Simultaneous determination of 12 index components and compatibility changes in Longchai decoction by liquid chromatography-mass spectrometry. |
| PubMed:[Breeding of new varieties "zhongchai no. 2" and "zhongchai no. 3" of Bupleurum chinense]. |
| PubMed:Saponins isolated from Bupleurum falcatum L.; components of saikosaponin b. |
| PubMed:Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells. |
| PubMed:Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry. |
| PubMed:Interaction of the main components from the traditional Chinese drug pair Chaihu-Shaoyao based on rat intestinal absorption. |
| PubMed:An Ultra-Performance Liquid Chromatography Photodiode Array Detection Tandem Mass Spectrometric Method for Simultaneous Determination of Seven Major Bioactive Constituents in Xiaochaihutang and Its Application to Fourteen Compatibilities Study. |
| PubMed:Chemical and biological comparison of raw and vinegar-baked Radix Bupleuri. |
| PubMed:Application of accelerated solvent extraction to the investigation of saikosaponins from the roots of Bupleurum falcatum. |
| PubMed:Standardized extract of Vitex doniana Sweet stalls protein oxidation, lipid peroxidation and DNA fragmention in acetaminophen-induced hepatotoxicity. |
| PubMed:Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species. |
| PubMed:[Studies on antinephritic effects of plant components in rats (1). Effects of saikosaponins original-type anti-GBM nephritis in rats and its mechanisms]. |
| PubMed:Optimization of supercritical fluid extraction of saikosaponins from Bupleurum falcatum with orthogonal array design. |
| PubMed:Shu‑Yu capsule, a Traditional Chinese Medicine formulation, attenuates premenstrual syndrome depression induced by chronic stress constraint. |
| PubMed:Quality control of Chinese medicinal preparations LC/ESI(+)/MS/MS analyses of saikosaponins-a and -c as markers of Bupleuri radix samples. |
| PubMed:Structural transformation of saikosaponins by gastric juice and intestinal flora. |
| PubMed:Saikosaponin‑d suppresses the expression of cyclooxygenase‑2 through the phospho‑signal transducer and activator of transcription 3/hypoxia‑inducible factor‑1α pathway in hepatocellular carcinoma cells. |
| PubMed:Modulatory effects of extracts of vinegar-baked Radix Bupleuri and saikosaponins on the activity of cytochrome P450 enzymes in vitro. |
| PubMed:Cell type-specific qualitative and quantitative analysis of saikosaponins in three Bupleurum species using laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry. |
| PubMed:Saikosaponin‑d inhibits proliferation of DU145 human prostate cancer cells by inducing apoptosis and arresting the cell cycle at G0/G1 phase. |
| PubMed:[Optimization of the ultrasound assisted extraction of saikosaponins from Bupleurum falcatum using response surface methodology]. |
| PubMed:Effects of Bupleurum scorzoneraefolium, Bupleurum falcatum, and saponins on nephrotoxic serum nephritis in mice. |
| PubMed:Antidepressant-like effects of Xiaochaihutang in a rat model of chronic unpredictable mild stress. |
| PubMed:Traditional Chinese medicine and related active compounds: a review of their role on hepatitis B virus infection. |
| PubMed:Analysis of the traditional medicine YiGan San by the fragmentation patterns of cadambine indole alkaloids using HPLC coupled with high-resolution MS. |
| PubMed:An LC-MS method for simultaneous determination of nine ginsenosides in rat plasma and its application in pharmacokinetic study. |
| PubMed:Efficient production of saikosaponins in Bupleurum falcatum root fragments combined with signal transducers. |
| PubMed:[Determination of content of saikoside in Bupleurum Chinense from different sources]. |
| PubMed:High performance liquid chromatographic assay of saikosaponins from radix Bupleuri in China. |
| PubMed:Extraction efficiency of shosaikoto (xiaochaihu tang) and investigation of the major constituents in the residual crude drugs. |
| PubMed:[Expression analysis of glycosyltransferase BcUGT1 from Bupleurum chinense DC. and its expression in E. coli and the target protein purification]. |
| PubMed:Analysis of saikosaponins in Bupleuri Radix and Caihu-shugan-san using reversed-phase HPLC with pulsed amperometric detection. |
| PubMed:Qualitative and quantitative analysis of nine major compounds in the Bozhougyiqi-Tang using a high-performance liquid chromatography coupled with a diode array detector and electrospray ionization mass spectrometer. |
| PubMed:Neuroprotective effects of total saikosaponins of Bupleurum yinchowense on corticosterone-induced apoptosis in PC12 cells. |
| PubMed:[Identification of the metabolites of Sinisan extract in rat plasma, urine, feces and bile after intragastric administration]. |
| PubMed:Oleanene glycosides of the aerial parts and seeds of Bupleurum falcatum and the aerial parts of Bupleurum rotundifolium, and their evaluation as anti-hepatitis agents. |
| PubMed:Quality control of tuirejieduling granules using high-performance liquid chromatography fingerprint method and simultaneous determination of four main active ingredients. |
| PubMed:Fast determination of saikosaponins in Bupleurum by rapid resolution liquid chromatography with evaporative light scattering detection. |
| PubMed:[Chemical constituents of the roots of Bupleurum longicaule Wall. ex DC. var. franchetii de Boiss and B. chaishoui Shan et Sheh]. |
| PubMed:Anti-growth effects with components of Sho-saiko-to (TJ-9) on cultured human hepatoma cells. |
| PubMed:[Structure of secondary saikosaponins in saiko decoction]. |
| PubMed:[Chemical constituents of n-BuOH extract of Comastoma pedunculatum]. |
| PubMed:Gene regulation patterns in triterpene biosynthetic pathway driven by overexpression of squalene synthase and methyl jasmonate elicitation in Bupleurum falcatum. |
| PubMed:Study on the noncovalent interactions of saikosaponins and cytochrome c by electrospray ionization mass spectrometry. |
| PubMed:Role of four major components in the effect of Si-Ni-San, a traditional Chinese prescription, against contact sensitivity in mice. |
| PubMed:Induction of differentiation in rat C6 glioma cells with Saikosaponins. |
| PubMed:Antiviral effects of saikosaponins on human coronavirus 229E in vitro. |
| PubMed:[Saponins in Bupleurum smithii Wolff var. parvifolium Shan et Y. Li]. |
| PubMed:[Isolation and identification of two new saponins from Bupleurum smithii Wolff]. |
| PubMed:[Cloning of UGT gene of Bupleurum chinense and construction of over expressing and RNAi transgenic vectors]. |
| PubMed:[Effect of Saikosaponins-d on reversing malignant phenotype of HepG2 cells in vitro]. |
| PubMed:Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell lines. |
| PubMed:[Research on mechanism of energy metabolism disorders of rat's hepatoxicity induced by saikosaponins]. |
| PubMed:[Study on the optimal extraction process of chaihushugan powder]. |
| PubMed:Visual detection of saikosaponins by on-membrane immunoassay and estimation of traditional Chinese medicines containing Bupleuri radix. |
| PubMed:Effects of Saireito, a Japanese herbal medicine, on edema via antagonistic actions against aldosterone in anti-GBM nephritic rats. |
| PubMed:A novel analytical ELISA-based methodology for pharmacologically active saikosaponins. |
| PubMed:Enzymes responsible for the metabolism of saikosaponins from Eubacterium sp. A-44, a human intestinal anaerobe. |
| PubMed:Effects of nine active ingredients in Chinese herbal medicine sho-saiko-to on 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide mutagenicity. |
| PubMed:Sho-saiko-to (Xiao-Chai-Hu-Tang) and crude saikosaponins inhibit hepatitis B virus in a stable HBV-producing cell line. |
| PubMed:Saikosaponins: a potential treatment option for systemic lupus erythematosus. |
| PubMed:Glaucasides A-C, three saikosaponins from Atriplex glauca L. var. ifiniensis (Caball) Maire. |
| PubMed:Fast and sensitive LC-DAD-ESI/MS method for analysis of saikosaponins c, a, and d from the roots of Bupleurum Falcatum (Sandaochaihu). |
| PubMed:Pharmacological evaluation of several major ingredients of Chinese herbal medicines in human hepatoma Hep3B cells. |
| PubMed:[Study on hepatotoxicity on rats caused by crude extracts of total saikosaponins and correlation with oxidative damage mechanism]. |
| PubMed:Identification and determination of the saikosaponins in Radix bupleuri by accelerated solvent extraction combined with rapid-resolution LC-MS. |
| PubMed:Cytotoxic activity and inhibitory effect on nitric oxide production of triterpene saponins from the roots of Physospermum verticillatum (Waldst & Kit) (Apiaceae). |
| PubMed:[Effect of chailing decoction and its active ingredients on experimental nephritis in rats]. |
| PubMed:Purification of saponin compounds in Bupleurum falcatum by solvent partitioning and preparative LC. |
| PubMed:Saikosaponins from roots of Bupleurum scorzonerifolium. |
| PubMed:Properties of ginseng saponin inhibition of catecholamine secretion in bovine adrenal chromaffin cells. |
| PubMed:Erythrocyte membrane stabilization by plant saponins and sapogenins. |
| PubMed:Suppressive effects of sairei-to on monoclonal antibody 1-22-3-induced glomerulonephritis: analysis of effective components. |
| PubMed:Effects of saiboku-to (TJ-96) on the production of platelet-activating factor in human neutrophils. |
| PubMed:Simultaneous determination of ginsenosides and saikosaponins by high-performance liquid chromatography. |
| PubMed:Comparison between evaporative light scattering detection and charged aerosol detection for the analysis of saikosaponins. |
| PubMed:Inhibition of human renin activity by saponins. |
| PubMed:Reactive oxygen species mediated sustained activation of protein kinase C alpha and extracellular signal-regulated kinase for migration of human hepatoma cell Hepg2. |
| PubMed:Phenethyl alcohol glycosides and isopentenol glycoside from fruit of Bupleurum falcatum. |
| PubMed:Inhibitory effect of bupleuri radix saponins on adhesion of some solid tumor cells and relation to hemolytic action: screening of 232 herbal drugs for anti-cell adhesion. |
| PubMed:[Advances in mechanisms of saikosaponins in preventing and treating liver disease]. |
| PubMed:[Effect of saikosaponins on epileptic rat electroenciphalogram]. |
| PubMed:[Studies on technology of supercritical-CO2 fluid extraction for volatile oils and saikosaponins in Bupleurum chinense DC]. |
| PubMed:[Determination of saikosaponins in radix Bupleuri using HPLC]. |
| PubMed:In vivo and in vitro antiinflammatory activity of saikosaponins. |
| PubMed:[The structure activity relationship of saikosaponins and glycyrrhizin derivatives for Na+, K(+)-ATPase inhibiting action]. |
| PubMed:[The identification and determination of marker substances in xiaoyao wan by three dimensional HPLC]. |
| PubMed:Evaluation of traditional Chinese herbal medicine: Chaihu (Bupleuri Radix) by both high-performance liquid chromatographic and high-performance thin-layer chromatographic fingerprint and chemometric analysis. |
| PubMed:Separation and isolation methods for analysis of the active principles of Sho-saiko-to (SST) oriental medicine. |
| PubMed:Phytochemical analysis of anti-atherogenic constituents of Xue-Fu-Zhu-Yu-Tang using HPLC-DAD-ESI-MS. |
| PubMed:[Chemical constituents analysis on anticonvulsive effect of three extracts from radix bupleuri]. |
| PubMed:Enhancement of the mutagenicity of Trp-P-1, Trp-P-2 and benzo[a]pyrene by bupleuri radix extract. |
| PubMed:Natural products as promising drug candidates for the treatment of hepatitis B and C. |
| PubMed:Application of centrifugal partition chromatography coupled with evaporative light scattering detection for the isolation of saikosaponins-a and -c from Bupleurum falcatum roots. |
| PubMed:Characterization and identification of saikosaponins in crude extracts from three Bupleurum species using LC-ESI-MS. |
| PubMed:[Aike mixture has good anti-inflammatory and analgesic effects on mice]. |
| PubMed:[Saikosaponins inhibit increased glutamate and GABA expressions in the hippocampus of pentetrazole-induced slow kindling rats]. |
| PubMed:[Studies on fingerprints of Bupleurum chinense from Hebei Province with HPLC-UV]. |
| PubMed:High-performance liquid chromatographic method for simultaneous quantification of eight major biologically active ingredients in 'Da-Chai-Hu-Tang' preparation. |
| PubMed:Determination of saikosaponins a, c, and d in Bupleurum Chinese DC from different areas by capillary zone electrophoresis. |
| PubMed:[Advances in the study on medicament portions of caihu]. |
| PubMed:[Somatic hybridization between carrot and Bupleurum scorzonerifolium and esteras isoenzyme analysis]. |
| PubMed:Antiviral activity of seven iridoids, three saikosaponins and one phenylpropanoid glycoside extracted from Bupleurum rigidum and Scrophularia scorodonia. |
| PubMed:The Chinese medicine Bu-Zhong-Yi-Qi-Tang inhibited proliferation of hepatoma cell lines by inducing apoptosis via G0/G1 arrest. |
| PubMed:Sho-saiko-to: Japanese herbal medicine for protection against hepatic fibrosis and carcinoma. |
| PubMed:Triterpenoid saponins from Bupleurum smithii var. parvifolium. |
| PubMed:[Production of medicinal plants by soilless culture system. I. Studies of morphological characteristics and saikosaponins content in Bupleurum falcatum cultivated by Ebb & Flood system]. |
| PubMed:Anti-inflammatory activity of saikosaponins from Heteromorpha trifoliata. |
| PubMed:[A histochemical study of saikosaponins]. |
| PubMed:Evaluation of root quality of Bupleurum species by TLC scanner and the liver protective effects of "xiao-chai-hu-tang" prepared using three different Bupleurum species. |
| PubMed:[Comparative studies on the roots of wild and cultured Bupleurum chinense DC]. |
| PubMed:Studies of the combined use of steroid and Shosaikoto, one of the Kampohozai (Chinese traditional medicine), on pituitary adrenocortical axis function and immune responses. |
| PubMed:Effects of saikosaponins on liver tyrosine aminotransferase activity induced by cortisone in adrenalectomized rats. |
| PubMed:Pharmacological influence of saikosaponins on prostaglandin E2 production by peritoneal macrophages. |
| PubMed:[Determination of saikosaponins in Chinese medicinal extracts containing Bupleuri radix]. |
| PubMed:The anti-allergic inflammation action of Saikosaponins. |
| PubMed:[Preventive and therapeutic actions of glycyrrhizin, glycyrrhetic acid and crude saikosides on experimental liver cirrhosis in rats]. |
| PubMed:Effects of saikosaponins on biological membranes. 3. Ultrastructural studies on effects of saikosaponins on the cell surface. |
| PubMed:Chemical structures and corticosterone secretion-inducing activities of saikosaponins. |
| PubMed:Pharmacological actions of saikosaponins isolated from Bupleurum falcatum. 1. Effects of saikosaponins on liver function. |
| PubMed:Effects of saikosaponins on the metabolic actions of adrenaline, ACTH and insulin on the fat cells. |
| PubMed:[Separation and refine of Xiaoyao Pill by macroporous adsorption resin]. |
| PubMed:A survey of Chinese herbal ingredients with liver protection activities. |
| PubMed:[Effect of saikosaponins-d on cyclooxygenase-2 expression of human hepatocellular carcinoma cell line SMMC-7721]. |
| PubMed:[Effect of saikosaponins on glial fibrillary acidic protein expression in hippocampal astrocytes of pentetrazole-induced chronic kindling rats]. |
| PubMed:[Effect of saikosaponins on epileptic seizure and EEG in pentetrazole-induced chronic kindling rats]. |
| PubMed:[Advances in the study of anti-inflammatory and immunoregulatory effects of saikosaponins and their similar substances]. |
| PubMed:Biologically active triterpene saponins from Bupleurum fruticosum. |
| PubMed:The herbal medicine sho-saiko-to inhibits proliferation of cancer cell lines by inducing apoptosis and arrest at the G0/G1 phase. |
| PubMed:Clinoposaponins I-V, new oleanane-triterpene saponins from Clinopodium gracile O. Kuntze. |
| PubMed:Anatomical and histological studies of Bupleuri radix. |
| PubMed:[Advances in research on the chemistry of saponins in Bupleurum]. |
| PubMed:Purification of saikosaponins a, c and d. Application of large-scale reversed high-performance liquid chromatography. |
| PubMed:[Variation of saponins for Bupleurm scorzonerifolium and B. chinese in the extraction process and their effect on hemolysis]. |
| PubMed:Effects of Saikosaponins on Liver Tyrosine Aminotransferase Activity induced by Cortisone in Adrenalectomized Rats. |
| PubMed:Effect of saikosaponins on dexamethasone suppression of the pituitary-adrenocortical system. |
| PubMed:[Comparison of the quality of cultivated and wild Bupleurum chinensis]. |
| PubMed:[Research on the pharmacology of Bupleurum chinensis]. |
| PubMed:[Anti-inflammatory effect of saikosaponins (author's transl)]. |
3D/inchi