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gossypol acetic acid

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CAS Number: 12542-36-8Picture of molecule3D/inchi
Other(deleted CASRN):104257-14-9
FDA UNII: S7RL72610R
MDL:MFCD00058385
Molecular Weight:578.61498000
Formula:C32 H34 O10
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
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PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 707.90 °C. @ 760.00 mm Hg (est)
Flash Point: 745.00 °F. TCC ( 395.90 °C. ) (est)
logP (o/w): 6.157 (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Gossypol Acetic Acid >98%
Odor: characteristic
Use: Acetate gossypol may represent a promising new anticancer agent with a novel molecular mechanism and warrants further investigation as a single agent, or in combination with other chemotherapeutics, for human multiple myeloma with Bcl-2 overexpression.
Carbosynth
For experimental / research use only.
Gossypol-acetic acid
Changsha Organic Herb
Cotton Seed Extract
Glentham Life Sciences
Gossypol-acetic acid
Santa Cruz Biotechnology
For experimental / research use only.
Gossypol-acetic acid
Shaanxi Y-Herb Biotechnology
98% Acetate Gossypol Cotton Seed Extract Powder CAS 12542-36-8 2 Years Shelf Life
Sigma-Aldrich
For experimental / research use only.
(±)-Gossypol-acetic acid
crystalline complex consisting of equimolar quantities of gossypol and acetic acid, ∼95%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-cat LDLo 75 mg/kg
Journal of Agricultural and Food Chemistry. Vol. 17, Pg. 497, 1969.

oral-man TDLo 282 mg/kg/63W-
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Fertility and Sterility. Vol. 48, Pg. 459, 1987.

oral-mouse LDLo 3000 mg/kg
Biomaterials, Medical Devices, and Artificial Organs. Vol. 12, Pg. 1, 1984.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for gossypol acetic acid usage levels up to:
 not for fragrance use.
 
Recommendation for gossypol acetic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
ClinicalTrials.gov:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :227456
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
aceticacid;7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
Chemidplus:0012542368
RTECS:MD7360000 for cas# 12542-36-8
 
References:
 aceticacid;7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):227456
Pubchem (sid):135232160
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 aceticacid;7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
 gossypol-acetic acid
(±)-gossypol-acetic acid
 
 
Notes:
None found
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