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oleuropein
2H-pyran-4-acetic acid, 3-ethylidene-2-(.beta.-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl ester, (2S,3E,4S)-

Supplier Sponsors

CAS Number: 32619-42-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:251-129-6
FDA UNII: 2O4553545L
Nikkaji Web:J17.724E
MDL:MFCD16879008
XlogP3-AA:-0.40 (est)
Molecular Weight:540.51964000
Formula:C25 H32 O13
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 88.00 °C. @ 760.00 mm Hg
Boiling Point: 772.86 °C. @ 760.00 mm Hg (est)
Flash Point: 495.00 °F. TCC ( 257.00 °C. ) (est)
logP (o/w): -0.865 (est)
Soluble in:
 water, 1734 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Oleuropein 98%
BOC Sciences
For experimental / research use only.
Oleuropein 96%
Odor: characteristic
Use: Oleuropein isolated from the herb of Olea europaea L. It inhibits cell proliferation and induces apoptosis in breast cancer, colorectal cancer and thyroid cancer. antioxidant activity; anti-inflammatory agent
Changsha Organic Herb
Olea europaea Extract
Changsha Organic Herb
Olive Leaf Extract Oleuropein
Coompo
For experimental / research use only.
Oleuropein from Plants ≥96%
Odor: characteristic
Use: Oleuropein is the most important phenolic component in Mediterranean diet associated with low incidence of coronary heart disease (CHD) and certain cancers. It also related to longevity. Olive tree leaves were traditionally boiled and the liquid was used for therapeutic remedies. Olisoul may benefit on human health by the following ways, Boost immune system health. Support healthy blood pressure and cholesterol levels. Fight microbial, viral and fungal infections. Protective effect on osteoporosis. Powerful antioxidants, free radical scavenger. Promote heart health.
ExtraSynthese
For experimental / research use only.
Oleuropein (HPLC) ≥90%
Glentham Life Sciences
Oleuropein
Sabinsa Corporation
Oleuropein 80%
Santa Cruz Biotechnology
For experimental / research use only.
Oleuropein
Shaanxi Y-Herb Biotechnology
CAS 32619-42-4 Organic Olive Leaf Extract 40% Oleuropein Powder For Heart Health
Sigma-Aldrich: Sigma
For experimental / research use only.
Oleuropein ≥98.0%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for oleuropein usage levels up to:
 not for fragrance use.
 
Recommendation for oleuropein flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the substantiation of a health claim related to olive (Olea europaea L.) leaf water extract and increase in glucose tolerance pursuant to Article 13(5) of Regulation (EC) No 1924/2006
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281544
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
Chemidplus:0032619424
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281544
Pubchem (sid):135049031
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB35872
FooDB:FDB014653
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 olive
Search Trop Picture
 olive leaf
Search Trop Picture
 
Synonyms:
2-(3,4-dihydroxyphenyl)ethyl (2S-(2alpha,3E,4beta))-3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetate
 oleuroperin
2H-pyran-4-acetic acid, 3-ethylidene-2-(.beta.-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl ester, (2S,3E,4S)-
 

Articles:

PubMed:Characteristics of oleuropeinolytic strains of Lactobacillus plantarum group and influence on phenolic compounds in table olives elaborated under reduced salt conditions.
PubMed:Phytochemicals and other characteristics of croatian monovarietal extra virgin olive oils from oblica, lastovka and levantinka varieties.
PubMed:Ultrahigh-pressure liquid chromatography triple-quadrupole tandem mass spectrometry quantitation of polyphenols and secoiridoids in california-style black ripe olives and dry salt-cured olives.
PubMed:Phenolic profile characterization of chemlali olive stones by liquid chromatography-ion trap mass spectrometry.
PubMed:Oleuropein Suppresses LPS-Induced Inflammatory Responses in RAW 264.7 Cell and Zebrafish.
PubMed:Biotechnological innovations for table olives.
PubMed:Evidence of oleuropein degradation by olive leaf protein extract.
PubMed:Isolation and Characterization of a Secoiridoid Derivative from Two-Phase Olive Waste (Alperujo).
PubMed:Whole Lyophilized Olives as Sources of Unexpectedly High Amounts of Secoiridoids: The Case of Three Tuscan Cultivars.
PubMed:Nutraceuticals and amyloid neurodegenerative diseases: a focus on natural phenols.
PubMed:Computer-aided discovery of biological activity spectra for anti-aging and anti-cancer olive oil oleuropeins.
PubMed:Combined use of nitrogen and coatings to improve the quality of mechanically harvested Manzanilla olives.
PubMed:Recovering bioactive compounds from olive oil filter cake by advanced extraction techniques.
PubMed:Endogenous enzymes involved in the transformation of oleuropein in Spanish table olive varieties.
PubMed:Oleuropein attenuates visceral adiposity in high-fat diet-induced obese mice through the modulation of WNT10b- and galanin-mediated signalings.
PubMed:The role of structural C--H compared with phenolic OH sites on the antioxidant activity of oleuropein and its derivatives as a great non-flavonoid family of the olive components: a DFT study.
PubMed:Faecal microbial metabolism of olive oil phenolic compounds: in vitro and in vivo approaches.
PubMed:3,4-DHPEA-EA from Olea Europaea L. is effective against standard and clinical isolates of Staphylococcus sp.
PubMed:Influence of olive leaf processing on the bioaccessibility of bioactive polyphenols.
PubMed:A new extraction approach to correct the effect of apparent increase in the secoiridoid content after filtration of virgin olive oil.
PubMed:Biomimetic synthesis and antioxidant evaluation of 3,4-DHPEA-EDA [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate].
PubMed:Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice.
PubMed:Oleuropein as a bioactive constituent added in milk and yogurt.
PubMed:Effects of the dietary incorporation of olive leaves on growth performance, digestibility, blood parameters and meat quality of growing pigs.
PubMed:High-resolution mass spectrometry to evaluate the influence of cross-breeding segregating populations on the phenolic profile of virgin olive oils.
PubMed:Minor polar compounds in extra virgin olive oil: correlation between HPLC-DAD-MS and the Folin-Ciocalteu spectrophotometric method.
PubMed:Quantitative measurement of major secoiridoid derivatives in olive oil using qNMR. Proof of the artificial formation of aldehydic oleuropein and ligstroside aglycon isomers.
PubMed:Isolation of megaritolactones and other bioactive metabolites from 'megaritiki' table olives and debittering water.
PubMed:Antioxidant capacity of individual and combined virgin olive oil minor compounds evaluated at mild temperature (25 and 40°C) as compared to accelerated and antiradical assays.
PubMed:Radical-scavenging compounds from olive tree (Olea europaea L.) wood.
PubMed:Employing Alzheimer disease animal models for translational research: focus on dietary components.
PubMed:Bioavailability of phenolics from an oleuropein-rich olive (Olea europaea) leaf extract and its acute effect on plasma antioxidant status: comparison between pre- and postmenopausal women.
PubMed:Nutrition and healthy ageing: calorie restriction or polyphenol-rich "MediterrAsian" diet?
PubMed:Olive leaf extracts are a natural source of advanced glycation end product inhibitors.
PubMed:Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells.
PubMed:Effects of certain polyphenols and extracts on furans and acrylamide formation in model system, and total furans during storage.
PubMed:Insight into virgin olive oil secoiridoids characterization by high-resolution mass spectrometry and accurate mass measurements.
PubMed:Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaea L.) leaf extract.
PubMed:DPPH assay of vegetable oils and model antioxidants in protic and aprotic solvents.
PubMed:Selection of Lactobacillus plantarum strains to use as starters in fermented table olives: Oleuropeinase activity and phage sensitivity.
PubMed:Antioxidant activity of phenolic fractions in olive mill wastewater.
PubMed:Combined effect of starter culture and temperature on phenolic compounds during fermentation of Taggiasca black olives.
PubMed:A validated method for the determination of selected phenolics in olive oil using high-performance liquid chromatography with coulometric electrochemical detection and a fused-core column.
PubMed:Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents.
PubMed:Olive oil oleuropein has anti-breast cancer properties with higher efficiency on ER-negative cells.
PubMed:Comprehensive analysis of polyphenols in 55 extra virgin olive oils by HPLC-ECD and their correlation with antioxidant activities.
PubMed:Microchip electrophoresis with amperometric detection for a novel determination of phenolic compounds in olive oil.
PubMed:Influence of harvest year, cultivar and geographical origin on Greek extra virgin olive oils composition: a study by NMR spectroscopy and biometric analysis.
PubMed:Analytical evaluation of two monovarietal virgin olive oils cultivated in the south of Tunisia: Jemri-Bouchouka and Chemlali-Tataouin cultivars.
PubMed:Characterisation and phenolic profiles of two rare olive oils from southern Tunisia: Dhokar and Gemri-Dhokar cultivars.
PubMed:High-performance liquid chromatography-mass spectrometry profiling of phenolic compounds for evaluation of olive oil bitterness and pungency.
PubMed:Improvement of oleuropein extractability by optimising steam blanching process as pre-treatment of olive leaf extraction via response surface methodology.
PubMed:Reuse of drinking water treatment sludge for olive oil mill wastewater treatment.
PubMed:Factors influencing phenolic compounds in table olives (Olea europaea).
PubMed:β-Glucosidase involvement in the formation and transformation of oleuropein during the growth and development of olive fruits (Olea europaea L. cv. Arbequina) grown under different farming practices.
PubMed:Feasible application of a portable NIR-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production.
PubMed:Distribution of olive oil phenolic compounds in rat tissues after administration of a phenolic extract from olive cake.
PubMed:Oleuropein ameliorates acute colitis in mice.
PubMed:Wastes generated during the storage of extra virgin olive oil as a natural source of phenolic compounds.
PubMed:Phenolic composition, isolation, and structure of a new deoxyloganic acid derivative from Dhokar and Gemri-Dhokar olive cultivars.
PubMed:Gamma irradiation of air-dried olive leaves: Effective decontamination and impact on the antioxidative properties and on phenolic compounds.
PubMed:Simultaneous separation and purification of flavonoids and oleuropein from Olea europaea L. (olive) leaves using macroporous resin.
PubMed:New possibilities for the valorization of olive oil by-products.
PubMed:The activity of healthy olive microbiota during virgin olive oil extraction influences oil chemical composition.
PubMed:Oleuropein and derivatives from olives as Tau aggregation inhibitors.
PubMed:High-throughput assay of oleopentanedialdheydes in extra virgin olive oil by the UHPLC-ESI-MS/MS and isotope dilution methods.
PubMed:Influence of Eriophyid mites (Aculus olearius Castagnoli and Aceria oleae (Nalepa) (Acarina: Eriophyidae)) on some physical and chemical characteristics of Ayvalık variety olive fruit.
PubMed:Use of multivariate statistical techniques to optimize the simultaneous separation of 13 phenolic compounds from extra-virgin olive oil by capillary electrophoresis.
PubMed:Oleuropein attenuates hepatic steatosis induced by high-fat diet in mice.
PubMed:Wound repair potential of Olea europaea L. leaf extracts revealed by in vivo experimental models and comparative evaluation of the extracts' antioxidant activity.
PubMed:Effects of conventional heating on the stability of major olive oil phenolic compounds by tandem mass spectrometry and isotope dilution assay.
PubMed:Metabolites involved in oleuropein accumulation and degradation in fruits of Olea europaea L.: Hojiblanca and Arbequina varieties.
PubMed:Comparative study of virgin olive oil quality from single varieties cultivated in Chile and Spain.
PubMed:Phenol metabolism in the leaves of the olive tree (Olea europaea L.) cv. Picual, Verdial, Arbequina, and Frantoio during ripening.
PubMed:Hydroxytyrosol rich extract from olive leaves modulates cell cycle progression in MCF-7 human breast cancer cells.
PubMed:Characterization of antioxidant olive oil biophenols by spectroscopic methods.
PubMed:Hepatoprotective effect of oleuropein in mice: mechanisms uncovered by gene expression profiling.
PubMed:Separation and identification of phenolic compounds of extra virgin olive oil from Olea europaea L. by HPLC-DAD-SPE-NMR/MS. Identification of a new diastereoisomer of the aldehydic form of oleuropein aglycone.
PubMed:Sensory quality of functional beverages: bitterness perception and bitter masking of olive leaf extract fortified fruit smoothies.
PubMed:HPLC analysis of oleuropein, hydroxytyrosol, and tyrosol in stems and roots of Olea europaea L. cv. Picual during ripening.
PubMed:Oil content, phenolic profiling and antioxidant potential of Tunisian olive drupes.
PubMed:Effect of olive ripeness on chemical properties and phenolic composition of Chétoui virgin olive oil.
PubMed:Qualitative screening of phenolic compounds in olive leaf extracts by hyphenated liquid chromatography and preliminary evaluation of cytotoxic activity against human breast cancer cells.
PubMed:Contribution of flavonoids to the overall radical scavenging activity of olive (Olea europaea L.) leaf polar extracts.
PubMed:Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract.
PubMed:Olive oil phenols modulate the expression of metalloproteinase 9 in THP-1 cells by acting on nuclear factor-kappaB signaling.
PubMed:Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation.
PubMed:Bactericidal activity of glutaraldehyde-like compounds from olive products.
PubMed:Identification of Throuba Thassos, a traditional Greek table olive variety, as a nutritional rich source of oleuropein.
PubMed:Powerful protective role of 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde against erythrocyte oxidative-induced hemolysis.
PubMed:Synthesis, biological evaluation, and molecular modeling of oleuropein and its semisynthetic derivatives as cyclooxygenase inhibitors.
PubMed:Olive tree (Olea europaea) leaves: potential beneficial effects on human health.
PubMed:Tentative characterization of novel phenolic compounds in extra virgin olive oils by rapid-resolution liquid chromatography coupled with mass spectrometry.
PubMed:Phenylalanine ammonia-lyase, polyphenol oxidase, and phenol concentration in fruits of Olea europaea L. cv. Picual, Verdial, Arbequina, and Frantoio during ripening.
PubMed:Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation.
PubMed:Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats.
PubMed:Purification and characterization of an olive fruit beta-glucosidase involved in the biosynthesis of virgin olive oil phenolics.
PubMed:Evaluation of potential genotoxicity of virgin olive oil (VOO) using the drosophila wing-spot test.
PubMed:Effects of olive oil polyphenols on erythrocyte oxidative damage.
PubMed:Effect of malaxation conditions on phenol and volatile profiles in olive paste and the corresponding virgin olive oils (Olea europaea L. Cv. Cornicabra).
PubMed:Phenolic composition, sugar contents and antioxidant activity of Tunisian sweet olive cultivar with regard to fruit ripening.
PubMed:Impact of sampling parameters on the radical scavenging potential of olive (Olea europaea L.) leaves.
PubMed:Phytochemicals in olive-leaf extracts and their antiproliferative activity against cancer and endothelial cells.
PubMed:Debittering of olives by polyphenol oxidation.
PubMed:Influence of the decrease in oxygen during malaxation of olive paste on the composition of volatiles and phenolic compounds in virgin olive oil.
PubMed:Nutritional benefit of olive oil: the biological effects of hydroxytyrosol and its arylating quinone adducts.
PubMed:Solid-liquid transfer of biophenols from olive leaves for the enrichment of edible oils by a dynamic ultrasound-assisted approach.
PubMed:Isolation and characterization of a new hydroxytyrosol derivative from olive (Olea europaea) leaves.
PubMed:Tunisian table olive phenolic compounds and their antioxidant capacity.
PubMed:Liquid-liquid extraction for the enrichment of edible oils with phenols from olive leaf extracts.
PubMed:Changes in virgin olive oil quality during low-temperature fruit storage.
PubMed:Effect of the maturation process on the phenolic fractions, fatty acids, and antioxidant activity of the Chétoui olive fruit cultivar.
PubMed:Phenolic compounds and antioxidant activity of Italian extra virgin olive oil Monti Iblei.
PubMed:Retention and distribution of polyphenols after pan-frying of French fries in oils enriched with olive leaf extract.
PubMed:Main antimicrobial compounds in table olives.
PubMed:Encapsulation of olive leaf extract in beta-cyclodextrin.
PubMed:Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects.
PubMed:New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol.
PubMed:Effect of olive stoning on the volatile and phenolic composition of virgin olive oil.
PubMed:Irrigation effects on quality, phenolic composition, and selected volatiles of virgin olive oils cv. Leccino.
PubMed:Evaluation of the influence of thermal oxidation on the phenolic composition and on the antioxidant activity of extra-virgin olive oils.
PubMed:Small branches of olive tree: a source of biophenols complementary to olive leaves.
PubMed:Optimum bacteriocin production by Lactobacillus plantarum 17.2b requires absence of NaCl and apparently follows a mixed metabolite kinetics.
PubMed:High-yielding preparation of a stable precursor of hydroxytyrosol by total synthesis and from the natural glycoside oleuropein.
PubMed:Dysfunctionality of the xylem in Olea europaea L. Plants associated with the infection process by Verticillium dahliae Kleb. Role of phenolic compounds in plant defense mechanism.
PubMed:Novel secoiridoids with antioxidant activity from Australian olive mill waste.
PubMed:Bioscreening of Australian olive mill waste extracts: biophenol content, antioxidant, antimicrobial and molluscicidal activities.
PubMed:1H NMR monitoring of the canine metabolic profile after oral administration of xenobiotics using multivariate statistics.
PubMed:Adsorption of olive leaf (Olea europaea L.) antioxidants on silk fibroin.
PubMed:Evolution of minor polar compounds and antioxidant capacity during storage of bottled extra virgin olive oil.
PubMed:Secondary metabolism of olive secoiridoids. New microcomponents detected in drupes by electrospray ionization and high-resolution tandem mass spectrometry.
PubMed:Rapid quantification of the phenolic fraction of Spanish virgin olive oils by capillary electrophoresis with UV detection.
PubMed:Pro-oxidant activity of oleuropein determined in vitro by electron spin resonance spin-trapping methodology.
PubMed:Lipase production by yeasts from extra virgin olive oil.
PubMed:Comparison of the concentrations of phenolic compounds in olive oils and other plant oils: correlation with antimicrobial activity.
PubMed:Protective effects of extra virgin olive oil phenolics on oxidative stability in the presence or absence of copper ions.
PubMed:The fate of olive oil polyphenols in the gastrointestinal tract: implications of gastric and colonic microflora-dependent biotransformation.
PubMed:The use of Lactobacillus pentosus 1MO to shorten the debittering process time of black table olives (Cv. Itrana and Leccino): a pilot-scale application.
PubMed:Effects of copper on the antioxidant activity of olive polyphenols in bulk oil and oil-in-water emulsions.
PubMed:Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation.
PubMed:Antioxidant effect of two virgin olive oils depends on the concentration and composition of minor polar compounds.
PubMed:Effect of storage on secoiridoid and tocopherol contents and antioxidant activity of monovarietal extra virgin olive oils.
PubMed:Evaluation of phenolic compounds in virgin olive oil by direct injection in high-performance liquid chromatography with fluorometric detection.
PubMed:Factors affecting the contents of iridoid oleuropein in olive leaves (Olea europaea L.).
PubMed:Investigation of Australian olive mill waste for recovery of biophenols.
PubMed:Discrimination of olive oils and fruits into cultivars and maturity stages based on phenolic and volatile compounds.
PubMed:Absolute method for the assay of oleuropein in olive oils by atmospheric pressure chemical ionization tandem mass spectrometry.
PubMed:Development of a sensitive and specific solid phase extraction--gas chromatography-tandem mass spectrometry method for the determination of elenolic acid, hydroxytyrosol, and tyrosol in rat urine.
PubMed:Inhibition of Staphylococcus aureus by oleuropein is mediated by hydrogen peroxide.
PubMed:Kinetic study of the physicochemical and microbiological changes in "seasoned" olives during the shelf-life period.
PubMed:Characterization and quantification of phenolic compounds in olive oils by solid-phase extraction, HPLC-DAD, and HPLC-MS/MS.
PubMed:Antioxidant and anti-atherogenic activities of olive oil phenolics.
PubMed:Interactions of ferric ions with olive oil phenolic compounds.
PubMed:Antioxidant activity of olive pulp and olive oil phenolic compounds of the arbequina cultivar.
PubMed:Secoiridoids, tocopherols, and antioxidant activity of monovarietal extra virgin olive oils extracted from destoned fruits.
PubMed:Identification and antioxidant potential of flavonoids and low molecular weight phenols in olive cultivar chemlali growing in Tunisia.
PubMed:Qualitative and semiquantitative analysis of phenolic compounds in extra virgin olive oils as a function of the ripening degree of olive fruits by different analytical techniques.
PubMed:Comparative study on phenolic content and antioxidant activity during maturation of the olive cultivar Chemlali from Tunisia.
PubMed:Contribution of the phenolic fraction to the antioxidant activity and oxidative stability of olive oil.
PubMed:Phenolic antioxidants and the protection of low density lipoprotein from peroxynitrite-mediated oxidations at physiologic CO2.
PubMed:Comparison of the radical scavenging potential of polar and lipidic fractions of olive oil and other vegetable oils under normal conditions and after thermal treatment.
PubMed:Polyphenol changes during fermentation of naturally black olives.
PubMed:LC-MS investigation of oxidation products of phenolic antioxidants.
PubMed:Antioxidant effect of phenolic compounds, alpha-tocopherol, and other minor components in virgin olive oil.
PubMed:Main polyphenols in the bitter taste of virgin olive oil. Structural confirmation by on-line high-performance liquid chromatography electrospray ionization mass spectrometry.
PubMed:Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration.
PubMed:Quantitative changes in phenolic content during physiological development of the olive (Olea europaea) cultivar Hardy's Mammoth.
PubMed:Sensory properties of virgin olive oil polyphenols: identification of deacetoxy-ligstroside aglycon as a key contributor to pungency.
PubMed:Inhibitory activity of minor polyphenolic and nonpolyphenolic constituents of olive oil against in vitro low-density lipoprotein oxidation.
PubMed:Radioprotective effects in vivo of phenolics extracted from Olea europaea L. leaves against X-ray-induced chromosomal damage: comparative study versus several flavonoids and sulfur-containing compounds.
PubMed:Comparison of the antioxidant activities of extra virgin olive oils.
PubMed:Evaluation of antioxidant activity of some natural polyphenolic compounds using the Briggs-Rauscher reaction method.
PubMed:Phenolic compounds profile of cornicabra virgin olive oil.
PubMed:Identification of phenolic compounds in tissues of the novel olive cultivar hardy's mammoth.
PubMed:Deterioration of natural antioxidant species of vegetable edible oils during the domestic deep-frying and pan-frying of potatoes.
PubMed:Biological properties of olive oil phytochemicals.
PubMed:Microbiological activity in stored olive oil.
PubMed:Partition behavior of virgin olive oil phenolic compounds in oil-brine mixtures during thermal processing for fish canning.
PubMed:Comparison of radical scavenging effect, inhibition of microsomal oxygen free radical generation, and serum lipoprotein oxidation of several natural antioxidants.
PubMed:Supplementation of plasma with olive oil phenols and extracts: influence on LDL oxidation.
PubMed:Partitioning of olive oil antioxidants between oil and water phases.
PubMed:Bioactive derivatives from oleuropein by a biotransformation on Olea europaea leaf extracts.
PubMed:Changes in the phenolic composition of virgin olive oil from young trees (Olea europaea L. cv. Arbequina) grown under linear irrigation strategies.
PubMed:Isolation and characterization of the antioxidant component 3,4-dihydroxyphenylethyl 4-formyl-3-formylmethyl-4-hexenoate from olive (Olea europaea) leaves.
PubMed:Inactivation of cytochrome P450 by the food-derived complex phenol oleuropein.
PubMed:Antioxidant activity of the main bioactive derivatives from oleuropein hydrolysis by hyperthermophilic beta-glycosidase.
PubMed:Antioxidant activity of hydroxytyrosol acetate compared with that of other olive oil polyphenols.
PubMed:Effect of enzyme treatment during mechanical extraction of olive oil on phenolic compounds and polysaccharides.
PubMed:Modulation of the biosynthesis of some phenolic compounds in Olea europaea L. fruits: their influence on olive oil quality.
PubMed:Rapid high-performance liquid chromatography analysis for the quantitative determination of oleuropein in Olea europaea leaves.
PubMed:Phenolic Compounds in Different Olive Varieties.
PubMed:HPLC analysis of flavonoids and secoiridoids in leaves of Ligustrum vulgare L. (Oleaceae).
PubMed:Oleuropein site selective hydrolysis by technomimetic nuclear magnetic resonance experiments.
PubMed:Comparison among differential pulse voltammetry, amperometric biosensor, and HPLC/DAD analysis for polyphenol determination.
PubMed:Rapid evaluation of phenolic component profile and analysis of oleuropein aglycon in olive oil by atmospheric pressure chemical ionization-mass spectrometry (APCI-MS).
PubMed:Protective effect of oleuropein, an olive oil biophenol, on low density lipoprotein oxidizability in rabbits.
PubMed:NMR experiments of oleuropein biomimetic hydrolysis.
PubMed:Phenolic compounds in Spanish olive oils.
PubMed:Bioactive derivatives of oleuropein from olive fruits.
PubMed:Polyphenolic content in five tuscany cultivars of Olea europaea L.
PubMed:Quantitation of oleuropein in virgin olive oil by ionspray mass spectrometry-selected reaction monitoring.
PubMed:Phenolic compounds of olive fruit: one- and two-dimensional nuclear magnetic resonance characterization of Nüzhenide and its distribution in the constitutive parts of fruit.
PubMed:On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol.
PubMed:Modelling the effectiveness of a natural antimicrobial on Salmonella enteritidis as a function of concentration, temperature and pH, using conductance measurements.
PubMed:Inhibition of Salmonella enteritidis by oleuropein in broth and in a model food system.
PubMed:Effect of phenolic compounds and oleuropein on the germination of Bacillus cereus T spores.
PubMed:Utilization of oleuropein by microorganisms associated with olive fermentations.
PubMed:Studies on the mechanism of the antimicrobial action of oleuropein.
 
Notes:
iridoid isolated from leaves and fruit of olea and ligustrum (oleaceae). Bitter principle of olives. Nutriceutical with antioxidant props. Oleuropein is a chemical compound found in olive leaf from the olive tree (and leaves of privet) together with other closely related compounds such as 10-hydroxyoleuropein, ligstroside, and 10-hydroxyligstroside. All these compounds are tyrosol esters of elenolic acid that are further hydroxylated and glycosylated. Oleuropein and its metabolite hydroxytyrosol have powerful antioxidant activity both in vivo and in vitro and give extra-virgin olive oil its bitter, pungent taste. Oleuropein preparations have been claimed to strengthen the immune system.
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