EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

chelerythrine
[1,3]benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-

Supplier Sponsors

CAS Number: 34316-15-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:251-930-0
FDA UNII: E3B045W6X0
Nikkaji Web:J19.428J
XlogP3-AA:4.60 (est)
Molecular Weight:348.37826000
Formula:C21 H18 N O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:brown powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -0.401 (est)
Soluble in:
 water, 6.03 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Chelerythrine 98%
BOC Sciences
For experimental / research use only.
Chelerythrine
ExtraSynthese
For experimental / research use only.
Chelerythrine (HPLC) ≥90%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for chelerythrine usage levels up to:
 not for fragrance use.
 
Recommendation for chelerythrine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :2703
National Institute of Allergy and Infectious Diseases:Data
1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
Chemidplus:0000478035
 
References:
 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):2703
Pubchem (sid):135229888
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C12227
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 celandine greater celandine
Search Trop Picture
 
Synonyms:
[1,3]benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-
1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
1,2-dimethoxy-12-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-ium
1,2-dimethoxy-12-methyl-[1,3]dioxolo[4'',5'':4,5]benzo[1,2-c]phenanthridin-12-ium
1,2-dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium
1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium
1,2-dimethoxy-12-methyl[1,3]dioxolo[4,5]benzo[1,2-c]phenanthridin-12-ium
 toddalin
 toddaline
 

Articles:

PubMed:In vitro and in vivo investigations on the antitumour activity of Chelidonium majus.
PubMed:Reward memory relieves anxiety-related behavior through synaptic strengthening and protein kinase C in dentate gyrus.
PubMed:Partial effects of the protein kinase C inhibitor chelerythrine in a battery of tests for manic-like behavior in black Swiss mice.
PubMed:Antihyperglycemic action of sinapic acid in diabetic rats.
PubMed:TNFα regulates sugar transporters in the human intestinal epithelial cell line Caco-2.
PubMed:Integration of transcriptome, proteome and metabolism data reveals the alkaloids biosynthesis in Macleaya cordata and Macleaya microcarpa.
PubMed:Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory.
PubMed:Natural feed additive of Macleaya cordata: safety assessment in rats a 90-day feeding experiment.
PubMed:Delayed protection of tetramethylpyrazine on neonatal rat cardiomyocytes subjected to anoxia-reoxygenation injury.
PubMed:Variability in the yield of benzophenanthridine alkaloids in wildcrafted vs cultivated bloodroot (Sanguinaria canadensis L.).
PubMed:Quaternary benzo[c]phenathridine alkaloids sanguinarine and chelerythrine do not affect transcriptional activity of aryl hydrocarbon receptor: analyses in rat hepatoma cell line H4IIE.luc.
PubMed:Investigation of sanguinarine and chelerythrine effects on CYP1A1 expression and activity in human hepatoma cells.
PubMed:Mechanisms underlying anorexia after microinjection of bombesin into the lateral cerebroventricle.
PubMed:Sanguinarine and chelerythrine: assessment of safety on pigs in ninety days feeding experiment.
PubMed:Effects of leptin on hypothalamic arcuate neurons in Wistar and Zucker rats: an in vitro study.
PubMed:Effects of fasting on corticosterone production by zona fasciculata-reticularis cells in ovariectomized rats.
PubMed:Involvement of protein kinase C and tyrosine kinase in lipopolysaccharide-induced anorexia.
 
Notes:
None found
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