| PubMed:Icariin promotes directed chondrogenic differentiation of bone marrow mesenchymal stem cells but not hypertrophy in vitro. |
| PubMed:Simultaneous enrichment and separation of flavonoids from Herba Epimedii by macroporous resins coupled with preparative chromatographic method. |
| PubMed:Comparative binding affinities of flavonoid phytochemicals with bovine serum albumin. |
| PubMed:[Icariin promote maturation of osteoblasts in vitro by an estrogen-independent mechanism]. |
| PubMed:Effects of icariin on the regulation of the OPG‑RANKL‑RANK system are mediated through the MAPK pathways in IL‑1β‑stimulated human SW1353 chondrosarcoma cells. |
| PubMed:Roles of the antioxidant properties of icariin and its phosphorylated derivative in the protection against duck virus hepatitis. |
| PubMed:Rapid characterization and determination of multiple components in Bu-Shen-Yi-Qi-Fang by high-performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry. |
| PubMed:Exploring the Catalytic Promiscuity of a New Glycosyltransferase from Carthamus tinctorius. |
| PubMed:Protective effect of icariin on kidney in 5/6 nephrectomized rats and its mechanism. |
| PubMed:Icariin may benefit the mesenchymal stem cells of patients with steroid-associated osteonecrosis by ABCB1-promoter demethylation: a preliminary study. |
| PubMed:Icariin ameliorates neuropathological changes, TGF-β1 accumulation and behavioral deficits in a mouse model of cerebral amyloidosis. |
| PubMed:[Comparison of pharmaceutical chemistry difference of effective parts from yin teng gu bi kang prescription in normal rats and rats with acute blood stasis]. |
| PubMed:Icariin ameliorates cigarette smoke induced inflammatory responses via suppression of NF-κB and modulation of GR in vivo and in vitro. |
| PubMed:Effects of icariin on reproductive functions in male rats. |
| PubMed:[Simultaneous determination of ten constituents in the Chinese medicinal preparation fufangxingxiangtu' erfeng capsules by ultra performance liquid chromatography with tandem mass spectrometry]. |
| PubMed:Inhibitory effect of icariin on Ti-induced inflammatory osteoclastogenesis. |
| PubMed:Icariin stimulates the osteogenic differentiation of rat bone marrow stromal cells via activating the PI3K-AKT-eNOS-NO-cGMP-PKG. |
| PubMed:The regulatory role of icariin on apoptosis in mouse preimplantation embryos with reduced microRNA-21. |
| PubMed:Icariin attenuates angiotensin II-induced hypertrophy and apoptosis in H9c2 cardiomyocytes by inhibiting reactive oxygen species-dependent JNK and p38 pathways. |
| PubMed:Treatment effect of Bushen Huayu extract on postmenopausal osteoporosis in vivo. |
| PubMed:Icariin combined with breviscapine improves the erectile function of spontaneously hypertensive rats. |
| PubMed:Cytotoxic effect of icaritin and its mechanisms in inducing apoptosis in human burkitt lymphoma cell line. |
| PubMed:[Analysis on biotransformation of Epimedium brevicornu flavonoids]. |
| PubMed:[Morphological character of growth cycle for Epimedium acuminatim and icariin content analysis]. |
| PubMed:Comparative effects of hispidulin, genistein, and icariin with estrogen on bone tissue in ovariectomized rats. |
| PubMed:Icariin and icaritin stimulate the proliferation of SKBr3 cells through the GPER1-mediated modulation of the EGFR-MAPK signaling pathway. |
| PubMed:Involvement of PIKE in icariin induced cardiomyocyte differentiation from murine embryonic stem cells. |
| PubMed:Effect of icariin on UDP-glucuronosyltransferases in mouse liver. |
| PubMed:BuShenYiQi Formula strengthens Th1 response and suppresses Th2-Th17 responses in RSV-induced asthma exacerbated mice. |
| PubMed:Icariin promotes self-renewal of neural stem cells: an involvement of extracellular regulated kinase signaling pathway. |
| PubMed:Flavonoids from Herba epimedii selectively activate estrogen receptor alpha (ERα) and stimulate ER-dependent osteoblastic functions in UMR-106 cells. |
| PubMed:Icariin enhances radiosensitivity of colorectal cancer cells by suppressing NF-κB activity. |
| PubMed:Icariin prevents ovariectomy-induced bone loss and lowers marrow adipogenesis. |
| PubMed:Icariin decreases the expression of APP and BACE-1 and reduces the β-amyloid burden in an APP transgenic mouse model of Alzheimer's disease. |
| PubMed:Determination of flibanserin and tadalafil in supplements for women sexual desire enhancement using high-performance liquid chromatography with tandem mass spectrometer, diode array detector and charged aerosol detector. |
| PubMed:Icariin, a phosphodiesterase-5 inhibitor, improves learning and memory in APP/PS1 transgenic mice by stimulation of NO/cGMP signalling. |
| PubMed:[Study on different factors affecting the bionic enzymatic hydrolysis of icariin]. |
| PubMed:Icariin attenuates glucocorticoid insensitivity mediated by repeated psychosocial stress on an ovalbumin-induced murine model of asthma. |
| PubMed:Icariin-mediated inhibition of NF-κB activity enhances the in vitro and in vivo antitumour effect of 5-fluorouracil in colorectal cancer. |
| PubMed:Comparative studies on antioxidant activities of extracts and fractions from the leaves and stem of Epimedium koreanum Nakai. |
| PubMed:A comparative study on the metabolism of Epimedium koreanum Nakai-prenylated flavonoids in rats by an intestinal enzyme (lactase phlorizin hydrolase) and intestinal flora. |
| PubMed:Icariin Augments Bone Formation and Reverses the Phenotypes of Osteoprotegerin-Deficient Mice through the Activation of Wnt/ β -Catenin-BMP Signaling. |
| PubMed:Selective hydrolysis of flavonoid glycosides by Curvularia lunata. |
| PubMed:[Effect of icariin on osteoblastic differentiation gene expression of human periodontal ligament cells]. |
| PubMed:Icaritin attenuates cigarette smoke-mediated oxidative stress in human lung epithelial cells via activation of PI3K-AKT and Nrf2 signaling. |
| PubMed:Plant polyphenols in the treatment of age-associated diseases: revealing the pleiotropic effects of icariin by network analysis. |
| PubMed:Regulation of the levels of Smad1 and Smad5 in MC3T3-E1 cells by Icariine in vitro. |
| PubMed:Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model. |
| PubMed:[Effect of lcariin on bone destruction and serum RANKL/OPG levels in type II collagen-induced arthritis rats]. |
| PubMed:Interaction of the bioactive flavonol, icariin, with the essential human solute carrier transporters. |
| PubMed:Chemical profiling and quantification of Chinese medicinal formula Huang-Lian-Jie-Du decoction, a systematic quality control strategy using ultra high performance liquid chromatography combined with hybrid quadrupole-orbitrap and triple quadrupole mass spectrometers. |
| PubMed:Osteoblasts proliferation and differentiation stimulating activities of the main components of Fructus Psoraleae corylifoliae. |
| PubMed:Effect of Chinese traditional herb Epimedium grandiflorum C. Morren and its extract Icariin on osteoarthritis via suppressing NF-kappaB pathway. |
| PubMed:[Effects of icariin and genistein on peak bone mass in rats]. |
| PubMed:Epimedium extract promotes peripheral nerve regeneration in rats. |
| PubMed:A systematic review of the efficacy and pharmacological profile of Herba Epimedii in osteoporosis therapy. |
| PubMed:β-cyclodextrin assistant flavonoid glycosides enzymatic hydrolysis. |
| PubMed:Influence of the mixture of Epimedii Herba and Ginkgo Folium extracts on the coronary flow of isolated hearts in rats. |
| PubMed:Icariin induces osteoblast differentiation and mineralization without dexamethasone in vitro. |
| PubMed:Effect of icariin on cell proliferation and the expression of bone resorption/formation-related markers in human periodontal ligament cells. |
| PubMed:Icaritin opposes the development of social aversion after defeat stress via increases of GR mRNA and BDNF mRNA in mice. |
| PubMed:Effects of icariin on the alkline phosphatase activity of human periodontal ligament cells inhibited by lipopolysaccharide. |
| PubMed:[Comparison between icariin and genistein in osteogenic activity of marrow stromal cells]. |
| PubMed:Effects of compatibility of deproteinized antler cancellous bone with various bioactive factors on their osteogenic potential. |
| PubMed:Icariin protects rat cardiac H9c2 cells from apoptosis by inhibiting endoplasmic reticulum stress. |
| PubMed:[Mechanisms of icariin in regulating bone formation of osteoblasts and bone resorption of osteoclasts]. |
| PubMed:Icaritin synergistically enhances the radiosensitivity of 4T1 breast cancer cells. |
| PubMed:Icariin synergizes with arsenic trioxide to suppress human hepatocellular carcinoma. |
| PubMed:[Effects of icariin on beta-amyloid and neurotrophic factors in brain of mitochondrial deficiency model rats]. |
| PubMed:Dual-delivery of vancomycin and icariin from an injectable calcium phosphate cement-release system for controlling infection and improving bone healing. |
| PubMed:A novel gold nanoparticle-doped polyaniline nanofibers-based cytosensor confers simple and efficient evaluation of T-cell activation. |
| PubMed:Icariin: does it have an osteoinductive potential for bone tissue engineering? |
| PubMed:Icariside II induces apoptosis via inhibition of the EGFR pathways in A431 human epidermoid carcinoma cells. |
| PubMed:Icariin attenuates high glucose-induced type IV collagen and fibronectin accumulation in glomerular mesangial cells by inhibiting transforming growth factor-β production and signalling through G protein-coupled oestrogen receptor 1. |
| PubMed:Icariin induces osteoblast proliferation, differentiation and mineralization through estrogen receptor-mediated ERK and JNK signal activation. |
| PubMed:An inhibitor of cathepsin K, icariin suppresses cartilage and bone degradation in mice of collagen-induced arthritis. |
| PubMed:[Effect of icariin on the expression of receptor activator nuclear factor-κB ligand and osteoprotegerin of human periodontal ligament cells]. |
| PubMed:Icariin delivery porous PHBV scaffolds for promoting osteoblast expansion in vitro. |
| PubMed:Simultaneous determination of 5 major bioactive components in hugu capsule by HPLC-DAD. |
| PubMed:Icariin attenuates the enhanced prothrombotic state in atherosclerotic rabbits independently of its lipid-lowering effects. |
| PubMed:[Amelioration of icariin for the epididymis impairment induced by streptozocin (STZ) in rats]. |
| PubMed:Effect of β-cyclodextrin complexation on solubility and enzymatic hydrolysis rate of icariin. |
| PubMed:Variation of epimedins A - C and icariin in ten representative populations of Epimedium brevicornu Maxim., and implications for utilization. |
| PubMed:Fishing and knockout of bioactive compounds using a combination of high-speed counter-current chromatography (HSCCC) and preparative HPLC for evaluating the holistic efficacy and interaction of the components of Herba Epimedii. |
| PubMed:mGluR5 stimulating Homer-PIKE formation initiates icariin induced cardiomyogenesis of mouse embryonic stem cells by activating reactive oxygen species. |
| PubMed:A new strategy for the discovery of epimedium metabolites using high-performance liquid chromatography with high resolution mass spectrometry. |
| PubMed:[Affect regularity of medicinal species and heating time on flavonoids contents in Epimedium cut crude drug]. |
| PubMed:Icariin protects against glucocorticoid-induced osteoporosis in vitro and prevents glucocorticoid-induced osteocyte apoptosis in vivo. |
| PubMed:Quantitative LC-MS/MS method in urine for the detection of drugs used to reverse the effects of chemical castration. |
| PubMed:Icariin promotes histone acetylation and attenuates post-stroke cognitive impairment in the central cholinergic circuits of mice. |
| PubMed:Icariin delays homocysteine-induced endothelial cellular senescence involving activation of the PI3K/AKT-eNOS signaling pathway. |
| PubMed:Icariin and its emerging role in the treatment of osteoporosis. |
| PubMed:The expression of calcium-sensing receptor in mouse embryonic stem cells (mESCs) and its influence on differentiation of mESC into cardiomyocytes. |
| PubMed:Icariin potentiates the antitumor activity of gemcitabine in gallbladder cancer by suppressing NF-κB. |
| PubMed:Inhibition of Th1/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin. |
| PubMed:Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19). |
| PubMed:Effects and interaction of icariin, curculigoside, and berberine in er-xian decoction, a traditional chinese medicinal formula, on osteoclastic bone resorption. |
| PubMed:[Screening of bioactive components in epimedium for osteoporosis treatment by model population analysis]. |
| PubMed:[Inhibitory effect of icariin on acetylcholinesterase]. |
| PubMed:Comparative effects of er-xian decoction, epimedium herbs, and icariin with estrogen on bone and reproductive tissue in ovariectomized rats. |
| PubMed:[Analysis of the osteogenetic effects exerted on mesenchymal stem cell strain C3H10T1/2 by icariin via MAPK signaling pathway in vitro]. |
| PubMed:Variation of medicinal components in a unique geographical accession of horny goat weed Epimedium sagittatum Maxim. (Berberidaceae). |
| PubMed:Icariin stimulates the proliferation of rat Sertoli cells in an ERK1/2-dependent manner in vitro. |
| PubMed:[Effect of icariin on learning and memory abilities and activity of cholinergic system of senescence-accelerated mice SAMP10]. |
| PubMed:Drug-Drug Interactions Potential of Icariin and Its Intestinal Metabolites via Inhibition of Intestinal UDP-Glucuronosyltransferases. |
| PubMed:Enhancement of epimedium fried with suet oil based on in vivo formation of self-assembled flavonoid compound nanomicelles. |
| PubMed:Immunoadjuvant activity of icariin that induces Th1-type antibody in mice. |
| PubMed:[Variation of icariin and total flavonoid of Epimedium acuminatum in different parts and habitats]. |
| PubMed:Maohuoside A acts in a BMP-dependent manner during osteogenesis. |
| PubMed:[Comparison of effects of kaempferide and anhydroicaritin on biomineralization of cultured osteoblasts]. |
| PubMed:Epimedium koreanum Extract and Its Constituent Icariin Improve Motor Dysfunction in Spinal Cord Injury. |
| PubMed:[Phenotype-based primary screening for drugs promoting neuronal subtype differentiation in embryonic stem cells with light microscope]. |
| PubMed:Icariin inhibits corticosterone-induced apoptosis in hypothalamic neurons via the PI3-K/Akt signaling pathway. |
| PubMed:Icariin: a potential promoting compound for cartilage tissue engineering. |
| PubMed:Changes in the intestinal absorption mechanism of icariin in the nanocavities of cyclodextrins. |
| PubMed:[Research on the preparative method of Arctigenin]. |
| PubMed:Icariin promotes bone formation via the BMP-2/Smad4 signal transduction pathway in the hFOB 1.19 human osteoblastic cell line. |
| PubMed:Preparation and biological evaluation of chitosan-collagen-icariin composite scaffolds for neuronal regeneration. |
| PubMed:Icariin enhances the healing of rapid palatal expansion induced root resorption in rats. |
| PubMed:Icariin associated with exercise therapy is an effective treatment for postmenopausal osteoporosis. |
| PubMed:[Comparative study on chemical quality of main species of epimedium]. |
| PubMed:Herba epimedii flavonoids suppress osteoclastic differentiation and bone resorption by inducing G2/M arrest and apoptosis. |
| PubMed:[Icariin reduces mitochondrial oxidative stress injury in diabetic rat hearts]. |
| PubMed:Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling. |
| PubMed:High-performance liquid chromatography-based multivariate analysis to predict the estrogenic activity of an Epimedium koreanum extract. |
| PubMed:Effect of icarisid II on diabetic rats with erectile dysfunction and its potential mechanism via assessment of AGEs, autophagy, mTOR and the NO-cGMP pathway. |
| PubMed:Chemoimmunomodulation of MDSCs as a novel strategy for cancer therapy. |
| PubMed:Icariin improves cognitive deficits and activates quiescent neural stem cells in aging rats. |
| PubMed:Impaired hypothalamic insulin signaling in CUMS rats: restored by icariin and fluoxetine through inhibiting CRF system. |
| PubMed:Estrogenic/antiestrogenic activities of a Epimedium koreanum extract and its major components: in vitro and in vivo studies. |
| PubMed:The beneficial effect of Icariin on bone is diminished in osteoprotegerin-deficient mice. |
| PubMed:Metabolite profiles of icariin in rat plasma by ultra-fast liquid chromatography coupled to triple-quadrupole/time-of-flight mass spectrometry. |
| PubMed:[Chinese herbal drugs for erectile dysfunction through NO-cGMP-PDE5 signaling pathway]. |
| PubMed:Effects of icariside II on improving erectile function in rats with streptozotocin-induced diabetes. |
| PubMed:[Study on extraction process for the icariin of hugu capsule with ultrasonic technology]. |
| PubMed:Peripubertal administration of icariin and icaritin advances pubertal development in female rats. |
| PubMed:Icariin ameliorates streptozotocin-induced diabetic retinopathy in vitro and in vivo. |
| PubMed:Icariin promotes extracellular matrix synthesis and gene expression of chondrocytes in vitro. |
| PubMed:Eradication of Propionibacterium acnes biofilms by plant extracts and putative identification of icariin, resveratrol and salidroside as active compounds. |
| PubMed:[Comparative study on absorption kinetics in intestines of rats of epimedii foliunm of Xianlinggubao capsules prepared by different processes]. |
| PubMed:[Preparation of flavonol glycoside reference standard series from Epimedium brevicornum Maxim using pilot-scale preparative high performance liquid chromatography]. |
| PubMed:Pharmacokinetics and tissue distribution profile of icariin propylene glycol-liposome intraperitoneal injection in mice. |
| PubMed:Metabolite profiling of four major flavonoids of Herba Epimedii in zebrafish. |
| PubMed:Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans. |
| PubMed:Different molecular targets of Icariin on bMSCs in CORT and OVX -rats. |
| PubMed:[Immunoregulatory mechanisms of an optimal Chinese herbal monomer compound in mice with allergic rhinitis]. |
| PubMed:The dose-effect of icariin on the proliferation and osteogenic differentiation of human bone mesenchymal stem cells. |
| PubMed:Effects of natural products on the function of human organic anion transporting polypeptide 1B1. |
| PubMed:Icariin stimulates MC3T3-E1 cell proliferation and differentiation through up-regulation of bone morphogenetic protein-2. |
| PubMed:[Comparative study on effect of icariin and genistein on proliferation and mineralization of osteoblasts in vitro]. |
| PubMed:[Icariin and its pharmaceutical efficacy: research progress of molecular mechanism]. |
| PubMed:A combined chitosan/nano-size hydroxyapatite system for the controlled release of icariin. |
| PubMed:[Study of molecular mechanisms of fuyuan capsule, icariin and arasaponin R1 in treatment of osteoarthritis]. |
| PubMed:Attenuation of LPS-induced inflammation by ICT, a derivate of icariin, via inhibition of the CD14/TLR4 signaling pathway in human monocytes. |
| PubMed:Molecular mechanism of icariin on rat asthmatic model. |
| PubMed:Protective effect of Icariin on the early stage of experimental diabetic nephropathy induced by streptozotocin via modulating transforming growth factor β1 and type IV collagen expression in rats. |
| PubMed:[Effects of icariin on the proliferation, differentiation and maturation of rat calvarial osteoblasts in vitro]. |
| PubMed:[Effects of icariin on Bcl-2 and Bax protein expressions and eosinophils apoptosis in bronchial asthmatic mice]. |
| PubMed:Effects of icariin on improving erectile function in streptozotocin-induced diabetic rats. |
| PubMed:Rise of herbal and traditional medicine in erectile dysfunction management. |
| PubMed:[Experimental study on the mechanism of icariin improving human osteoblasts proliferation and the expression of OPG protein]. |
| PubMed:[Effects of icariin and icariside II on eNOS expression and NOS activity in porcine aorta endothelial cells]. |
| PubMed:Involvement of ubiquitin-proteasome system in icariin-induced cardiomyocyte differentiation of embryonic stem cells using two-dimensional gel electrophoresis. |
| PubMed:Icarisid II, a PDE5 inhibitor from Epimedium wanshanense, increases cellular cGMP by enhancing NOS in diabetic ED rats corpus cavernosum tissue. |
| PubMed:Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways. |
| PubMed:Icariin induces apoptosis in mouse MLTC-10 Leydig tumor cells through activation of the mitochondrial pathway and down-regulation of the expression of piwil4. |
| PubMed:Simultaneous quantification of Panax and Epimedium species using Rapid Resolution Liquid Chromatography (RRLC). |
| PubMed:[Comparative study on the osteogenic differentiation of rat bone marrow stromal cells effected by icariin and icariside II]. |
| PubMed:Icariin induces the expression of toll-like receptor 9 in ana-1 murine macrophages. |
| PubMed:Combined in vivo imaging and omics approaches reveal metabolism of icaritin and its glycosides in zebrafish larvae. |
| PubMed:[Simultaneous assay of epimedin A epimedin B, epimedin C and icariin in herba epimedii by QAMS]. |
| PubMed:A novel approach to simultaneous screening and confirmation of regulated pharmaceutical compounds in dietary supplements by LC/MS/MS with an information-dependent acquisition method. |
| PubMed:Icariin attenuates cardiac remodelling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure. |
| PubMed:[Icariin promotes osteogenic differentiation of rat bone marrow stromal cells in vitro]. |
| PubMed:Studies on target tissue distribution of ginsenosides and epimedium flavonoids in rats after intravenous administration of Jiweiling freeze-dried powder. |
| PubMed:[Total flavonoids and icariin contents of Epimedium pubescens in different types of communities and their relationships with soil factors]. |
| PubMed:Icariin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro. |
| PubMed:Synergistic or antagonistic effect of MTE plus TF or icariin from Epimedium koreanum on the proliferation and differentiation of primary osteoblasts in vitro. |
| PubMed:[Effects of active ingredients in three kidney-tonifying Chinese herbal drugs on gene expression profile of bone marrow stromal cells from a rat model of corticosterone-induced osteoporosis]. |
| PubMed:Role of intestinal hydrolase in the absorption of prenylated flavonoids present in Yinyanghuo. |
| PubMed:Icariin attenuates social defeat-induced down-regulation of glucocorticoid receptor in mice. |
| PubMed:Icariin and its derivative, ICT, exert anti-inflammatory, anti-tumor effects, and modulate myeloid derived suppressive cells (MDSCs) functions. |
| PubMed:Icariin inhibits hydrogen peroxide-induced toxicity through inhibition of phosphorylation of JNK/p38 MAPK and p53 activity. |
| PubMed:Neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons. |
| PubMed:Icariin induces mouse embryonic stem cell differentiation into beating functional cardiomyocytes. |
| PubMed:The effect of loading icariin on biocompatibility and bioactivity of porous β-TCP ceramic. |
| PubMed:Effect of icariin on bone formation during distraction osteogenesis in the rabbit mandible. |
| PubMed:[Quality research on Epimedium cut crude drug processed with oil]. |
| PubMed:Icariin improves memory impairment in Alzheimer's disease model mice (5xFAD) and attenuates amyloid β-induced neurite atrophy. |
| PubMed:[Comparative study on dissolution of Xianlinggubao capsules prepared by different processes]. |
| PubMed:Analysis of biliary excretion of icariin in rats. |
| PubMed:Icariin attenuates β-amyloid-induced neurotoxicity by inhibition of tau protein hyperphosphorylation in PC12 cells. |
| PubMed:Simultaneous determination of seven flavonoids in dog plasma by ultra-performance liquid chromatography-tandem mass spectrometry and its application to a bioequivalence study of bioactive components in Herba Epimedii and Er-Xian Decoction. |
| PubMed:Icariin derivative inhibits inflammation through suppression of p38 mitogen-activated protein kinase and nuclear factor-kappaB pathways. |
| PubMed:[Chinese medicinal monomer and compound for 60Co-gamma-induced spermatogenic disturbance in mice]. |
| PubMed:Icariin, a natural flavonol glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via a ROS/JNK-dependent mitochondrial pathway. |
| PubMed:[Experimental study of icariin in inducing bone marrow mesenchymal stem cell differentiation]. |
| PubMed:Flavonoids, apigenin and icariin exert potent melanogenic activities in murine B16 melanoma cells. |
| PubMed:[Study on preparation of icaritin by enzymolysis of icariin with snail hydrolase]. |
| PubMed:Icariin isolated from Epimedium brevicornum Maxim attenuates learning and memory deficits induced by d-galactose in rats. |
| PubMed:Icariin-mediated differentiation of mouse adipose-derived stem cells into cardiomyocytes. |
| PubMed:Icariin inhibits osteoclast differentiation and bone resorption by suppression of MAPKs/NF-κB regulated HIF-1α and PGE(2) synthesis. |
| PubMed:[Optimal combination of baicalin, icariin and Astragalus saponin I from a Chinese herbal compound Biminne]. |
| PubMed:Icariin inhibits hydrogen peroxide-mediated cytotoxicity by up-regulating sirtuin type 1-dependent catalase and peroxiredoxin. |
| PubMed:Icariin attenuates LPS-induced acute inflammatory responses: involvement of PI3K/Akt and NF-kappaB signaling pathway. |
| PubMed:Involvement of androgen receptor in nitric oxide production induced by icariin in human umbilical vein endothelial cells. |
| PubMed:Protective effects of icariin on brain dysfunction induced by lipopolysaccharide in rats. |
| PubMed:Icariin protects against brain injury by enhancing SIRT1-dependent PGC-1alpha expression in experimental stroke. |
| PubMed:Neuroprotective effects of icariin on memory impairment and neurochemical deficits in senescence-accelerated mouse prone 8 (SAMP8) mice. |
| PubMed:Liquid chromatography-tandem mass spectrometry analysis of metabolites in rats after administration of prenylflavonoids from Epimediums. |
| PubMed:Icariin attenuates lipopolysaccharide-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-kappaB and JNK/p38 MAPK pathways. |
| PubMed:In vivo and in vitro anti-inflammatory effects of a novel derivative of icariin. |
| PubMed:Icariin exterts negative effects on human gastric cancer cell invasion and migration by vasodilator-stimulated phosphoprotein via Rac1 pathway. |
| PubMed:[Absorption and metabolism of flavonoids in Herba Epimedii via rat intestinal perfusion model]. |
| PubMed:[Research on variation regularity of five main flavonoids contents in Epimedium and processed Epimedium]. |
| PubMed:Chemical pattern-aided classification to simplify the intricacy of morphological taxonomy of Epimedium species using chromatographic fingerprinting. |
| PubMed:Erectogenic and neurotrophic effects of icariin, a purified extract of horny goat weed (Epimedium spp.) in vitro and in vivo. |
| PubMed:Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells. |
| PubMed:Icariin inhibits the increased inward calcium currents induced by amyloid-beta(25-35) peptide in CA1 pyramidal neurons of neonatal rat hippocampal slice. |
| PubMed:Icariin protects murine chondrocytes from lipopolysaccharide-induced inflammatory responses and extracellular matrix degradation. |
| PubMed:An in vitro study on neuroprotective effects of serum containing Gengnianchun decoction and its main monomers against amyloid beta protein-induced cellular toxicity. |
| PubMed:Preparation of icariside II from icariin by enzymatic hydrolysis method. |
| PubMed:[Effect of icariin on the mRNA expressions of Cbfalpha1, BMP2, BMP4 in rat osteoblasts]. |
| PubMed:Anti-proliferative efficacy of icariin on HepG2 hepatoma and its possible mechanism of action. |
| PubMed:[Effects of icariin on expression of glucose regulated protein 78 in vascular smooth muscle cell induced by homocysteine]. |
| PubMed:Icariin inhibits neurotoxicity of beta-amyloid by upregulating cocaine-regulated and amphetamine-regulated transcripts. |
| PubMed:[Identifying the characteristics of FTIR spectra of herba epimedii icariin via wavelet analysis and RBF neural network]. |
| PubMed:Icariin inhibits beta-amyloid peptide segment 25-35 induced expression of beta-secretase in rat hippocampus. |
| PubMed:Icariin isolated from Epimedium pubescens regulates osteoblasts anabolism through BMP-2, SMAD4, and Cbfa1 expression. |
| PubMed:Icariin: a potential osteoinductive compound for bone tissue engineering. |
| PubMed:[Sampling in quality control of medicinal materials-A case of Epimedium]. |
| PubMed:Icariin attenuates chronic mild stress-induced dysregulation of the LHPA stress circuit in rats. |
| PubMed:Simultaneous determination of notoginsenoside R1, ginsenoside Rg1, Re, Rb1 and icariin in rat plasma by ultra-performance liquid chromatography-tandem mass spectrometry. |
| PubMed:[Effects of icariin on inflammation model stimulated by lipopolysaccharide in vitro and in vivo]. |
| PubMed:Synthesis and antimultidrug resistance evaluation of icariin and its derivatives. |
| PubMed:Separation and purification of epimedin A, B, C, and icariin from the medicinal herb Epimedium brevicornum maxim by dual-mode HSCCC. |
| PubMed:Pharmacokinetics of prenylflavonoids and correlations with the dynamics of estrogen action in sera following ingestion of a standardized Epimedium extract. |
| PubMed:In vivo pharmacokinetics comparisons of icariin, emodin and psoralen from gan-kang granules and extracts of herba Epimedii, Nepal dock root, Ficus hirta yahl. |
| PubMed:[Study on the interaction of hesperidin or icariin with lysozyme by fluorescence spectroscopy]. |
| PubMed:Icariin enhances neuronal survival after oxygen and glucose deprivation by increasing SIRT1. |
| PubMed:Antiosteoporotic activity of icariin in ovariectomized rats. |
| PubMed:[Progress of pharmacological research on icariin]. |
| PubMed:Protective effects of icariin on cognitive deficits induced by chronic cerebral hypoperfusion in rats. |
| PubMed:Effect of stability of internal standard on quantification of 15 flavonoids in Epimedium using CZE. |
| PubMed:Simple and sensitive liquid chromatography-tandem mass spectrometry assay for simultaneous measurement of five Epimedium prenylflavonoids in rat sera. |
| PubMed:[Effect of icariin on intermediate and advanced activation of murine T lymphocytes in vitro]. |
| PubMed:[Primary study on effect of various components of modified formula radix hedysari on peripheral nerve regeneration]. |
| PubMed:Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells. |
| PubMed:Potent inhibition of human phosphodiesterase-5 by icariin derivatives. |
| PubMed:[Absorption mechanism of icariin across Caco-2 monolayer model]. |
| PubMed:Antiosteoporotic chemical constituents from Er-Xian Decoction, a traditional Chinese herbal formula. |
| PubMed:Involvement of p38MAPK and reactive oxygen species in icariin-induced cardiomyocyte differentiation of murine embryonic stem cells in vitro. |
| PubMed:Intestinal absorption mechanisms of prenylated flavonoids present in the heat-processed Epimedium koreanum Nakai (Yin Yanghuo). |
| PubMed:Involvement of NF-kappaB and AP-1 activation in icariin promoted cardiac differentiation of mouse embryonic stem cells. |
| PubMed:Effects of icariin combined with Panax notoginseng saponins on ischemia reperfusion-induced cognitive impairments related with oxidative stress and CA1 of hippocampal neurons in rat. |
| PubMed:[Systematic studies on quality of main species of Herba epimedii]. |
| PubMed:Icariin induces osteogenic differentiation in vitro in a BMP- and Runx2-dependent manner. |
| PubMed:Simultaneous determination of seven flavonoids in Epimedium using pressurized liquid extraction and capillary electrochromatography. |
| PubMed:Determination of icariin in rat plasma by reverse-phase high-performance liquid chromatography after oral administration of a lipid-based suspension of Epimedium koreanum extract. |
| PubMed:Statistically designed enzymatic hydrolysis for optimized production of icariside II as a novel melanogenesis inhibitor. |
| PubMed:Icariin enhances the osteogenic differentiation of bone marrow stromal cells but has no effects on the differentiation of newborn calvarial osteoblasts of rats. |
| PubMed:Ethanol extract from Epimedium brevicornum attenuates left ventricular dysfunction and cardiac remodeling through down-regulating matrix metalloproteinase-2 and -9 activity and myocardial apoptosis in rats with congestive heart failure. |
| PubMed:Protective effect of icariin on DNA against radical-induced oxidative damage. |
| PubMed:[Research on quality of Epimedium extract in market]. |
| PubMed:[HPLC-MS3 analysis of chemical constituents in Epimedium brevicornum]. |
| PubMed:Trace analysis of icariin in human serum with dansyl chloride derivatization after oral administration of Epimedium decoction by liquid chromatography tandem mass spectrometry. |
| PubMed:Simultaneous determination of nine flavonoids and qualitative evaluation of Herba Epimedii by high performance liquid chromatography with ultraviolet detection. |
| PubMed:Simultaneous determination of icariin, icariside II and osthole in rat plasma after oral administration of the extract of Gushudan (a Chinese compound formulation) by LC-MS/MS. |
| PubMed:[Effects of Erxian Decoction and its separate prescriptions on the levels of luteinizing hormone and follicle-stimulating hormone in anterior pituitary cells from female rats]. |
| PubMed:Reactive oxygen species involved in prenylflavonoids, icariin and icaritin, initiating cardiac differentiation of mouse embryonic stem cells. |
| PubMed:Pharmacological activity of cardiovascular agents from herbal medicine. |
| PubMed:A rapid method for simultaneous determination of 15 flavonoids in Epimedium using pressurized liquid extraction and ultra-performance liquid chromatography. |
| PubMed:Simultaneous extraction of epimedin A, B, C and icariin from Herba Epimedii by ultrasonic technique. |
| PubMed:Fast quality control of Herba Epimedii by using Fourier transform infrared spectroscopy. |
| PubMed:Effect of lipid-based suspension of Epimedium koreanum Nakai extract on sexual behavior in rats. |
| PubMed:Icariin promotes expression of PGC-1alpha, PPARalpha, and NRF-1 during cardiomyocyte differentiation of murine embryonic stem cells in vitro. |
| PubMed:Simultaneous quantitation of five flavonoid glycosides in Herba Epimedii by high-performance liquid chromatography-tandem mass spectrometry. |
| PubMed:Icaritin and its glycosides enhance osteoblastic, but suppress osteoclastic, differentiation and activity in vitro. |
| PubMed:LC-MS/MS method for the simultaneous determination of icariin and its major metabolites in rat plasma. |
| PubMed:Hypouricemic action of selected flavonoids in mice: structure-activity relationships. |
| PubMed:HPLC analysis and pharmacokinetics of icariin in rats. |
| PubMed:Chemical constituents of roots of Epimedium wushanense and evaluation of their biological activities. |
| PubMed:[Comparison of antioxidative and antitumor activities of six flavonoids from Epimedium koreanum]. |
| PubMed:Simultaneous determination of 15 flavonoids in Epimedium using pressurized liquid extraction and high-performance liquid chromatography. |
| PubMed:Protective effects of icariin against learning and memory deficits induced by aluminium in rats. |
| PubMed:[Effect of er xian decoction and its subdivisions on granulosa cells secretory function in rats]. |
| PubMed:Icariin inhibits the osteoclast formation induced by RANKL and macrophage-colony stimulating factor in mouse bone marrow culture. |
| PubMed:[A review on research of raw material and cut crude drug of Herba epimedii in last ten years]. |
| PubMed:Icariin from Epimedium brevicornum attenuates chronic mild stress-induced behavioral and neuroendocrinological alterations in male Wistar rats. |
| PubMed:Icariin enhances endothelial nitric-oxide synthase expression on human endothelial cells in vitro. |
| PubMed:Effects of total flavonoids and flavonol glycosides from Epimedium koreanum Nakai on the proliferation and differentiation of primary osteoblasts. |
| PubMed:Comparison between HPLC and HPTLC densitometry for the determination of icariin from Epimedium koreanum extracts. |
| PubMed:Vasorelaxant effects of icariin on isolated canine coronary artery. |
| PubMed:Taxonomic, genetic, chemical and estrogenic characteristics of Epimedium species. |
| PubMed:Epimedium-derived phytoestrogen flavonoids exert beneficial effect on preventing bone loss in late postmenopausal women: a 24-month randomized, double-blind and placebo-controlled trial. |
| PubMed:A novel anticancer agent, icaritin, induced cell growth inhibition, G1 arrest and mitochondrial transmembrane potential drop in human prostate carcinoma PC-3 cells. |
| PubMed:Icariine stimulates proliferation and differentiation of human osteoblasts by increasing production of bone morphogenetic protein 2. |
| PubMed:[The effect of icariin and astragalosid I on the proliferation and differentiation of bone marrow stromal cells]. |
| PubMed:Effects of icariin on phosphodiesterase-5 activity in vitro and cyclic guanosine monophosphate level in cavernous smooth muscle cells. |
| PubMed:Effects of icariin on hypothalamic-pituitary-adrenal axis action and cytokine levels in stressed Sprague-Dawley rats. |
| PubMed:Effect of icariin on cyclic GMP levels and on the mRNA expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in penile cavernosum. |
| PubMed:The testosterone mimetic properties of icariin. |
| PubMed:Effects of Icariin on expression of OPN mRNA and type I collagen in rat osteoblasts in vitro. |
| PubMed:Icariin: a special antioxidant to protect linoleic acid against free-radical-induced peroxidation in micelles. |
| PubMed:Regulation of Cbfa1 expression by total flavonoids of Herba epimedii. |
| PubMed:Icariin-mediated expression of cardiac genes and modulation of nitric oxide signaling pathway during differentiation of mouse embryonic stem cells into cardiomyocytes in vitro. |
| PubMed:Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells. |
| PubMed:Antidepressant-like effect of icariin and its possible mechanism in mice. |
| PubMed:Optimization for quantitative determination of four flavonoids in Epimedium by capillary zone electrophoresis coupled with diode array detection using central composite design. |
| PubMed:Estrogenic effects of two derivatives of icariin on human breast cancer MCF-7 cells. |
| PubMed:Effects of icariin on erectile function and expression of nitric oxide synthase isoforms in castrated rats. |
| PubMed:Protective effects of icariin on neurons injured by cerebral ischemia/reperfusion. |
| PubMed:Screening of active compounds as neuromedin U2 receptor agonist from natural products. |
| PubMed:[Species and geographic distribution of large-flowered taxa of Epimedium in China]. |
| PubMed:[Effect of icariin on hypoxia induced vascular endothelial cells injury]. |
| PubMed:[Chemical constituents from herb of Epimedium brevicornum]. |
| PubMed:Protective effects of icariin on human umbilical vein endothelial cell injury induced by H2O2 in vitro. |
| PubMed:[Effects of Icariin on ovariectomized osteoporotic rats]. |
| PubMed:Icariin-mediated modulation of cell cycle and p53 during cardiomyocyte differentiation in embryonic stem cells. |
| PubMed:Osteoblastic proliferative activity of Epimedium brevicornum Maxim. |
| PubMed:[Preparation of two derivatives from icariin and investigation of their estrogen-like effects]. |
| PubMed:Inducible effects of icariin, icaritin, and desmethylicaritin on directional differentiation of embryonic stem cells into cardiomyocytes in vitro. |
| PubMed:Determination of rat urinary metabolites of icariin in vivo and estrogenic activities of its metabolites on MCF-7 cells. |
| PubMed:Preparative isolation and purification of three flavonoids from the Chinese medicinal plant Epimedium koreamum Nakai by high-speed counter-current chromatography. |
| PubMed:[Effects of Epimedium pubescens icariine on proliferation and differentiation of human osteoblasts]. |
| PubMed:[Study on water extraction process of Herba epimedii with microwave technology]. |
| PubMed:[Determination of epimedin C and icariin in Herba Epimedii by HPLC]. |
| PubMed:Quantitative and qualitative HPLC analysis of thermogenic weight loss products. |
| PubMed:The antioxidative effect of icariin in human erythrocytes against free-radical-induced haemolysis. |
| PubMed:Proliferation-stimulating effects of icaritin and desmethylicaritin in MCF-7 cells. |
| PubMed:Determination of icariin and metabolites in rat serum by capillary zone electrophoresis: rat pharmacokinetic studies after administration of icariin. |
| PubMed:[Effects of icariin on the erectile function and expression of nitrogen oxide synthase isoforms in corpus cavernosum of arterigenic erectile dysfunction rat model]. |
| PubMed:[Studies on extraction factors of buxueyangyan mixture]. |
| PubMed:[Comment on main species of herba epimedii]. |
| PubMed:[Effects of icariin on intracavernosal pressure and systematic arterial blood pressure of rat]. |
| PubMed:Cytotoxic effects of Coptis chinensis and Epimedium sagittatum extracts and their major constituents (berberine, coptisine and icariin) on hepatoma and leukaemia cell growth. |
| PubMed:Chemical and pharmacological investigations of Epimedium species: a survey. |
| PubMed:Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities. |
| PubMed:[Experimental studies of icariin on anticancer mechanism]. |
| PubMed:[Influence of icariin on cell membrane of highly metastatic human lung tumor cell line]. |
| PubMed:[Orthogonal experiments on extract-concentrate-spray drier related technological factors for shuguanwenjing granule]. |
| PubMed:[Quantitative determination of icariin in "tangzhi shuangjiang cha" by high performance liquid chromatography]. |
| PubMed:[Determination of the pKa value of icariin and its content in the Chinese herb medicine epimedium grandiflorum morr. by capillary electrophoresis]. |
| PubMed:[Advances in study on pharmacological effects of Epimedium]. |
| PubMed:[Studies on preparation of herba epimedii total flavonoids phytosomes and their pharmaceutics]. |
| PubMed:Purification of icariin from the extract of Epimedium segittatum using high-speed counter-current chromatography. |
| PubMed:[A review of pharmacological study on Epimedium grandiflorum Morr and its active constituents]. |
| PubMed:[Advances in the chemical study of Epimedium]. |
| PubMed:Flavonol glycosides from Epimedium sagittatum and their neurite outgrowth activity on PC12h cells. |
| PubMed:Electrophoretic behavior study and determination of some active components in Chinese medicinal preparations by capillary electrophoresis. |
| PubMed:Screening of anti-hypoxia/reoxygenation agents by an in vitro method. Part 2: Inhibition of tyrosine kinase activation prevented hypoxia/reoxygenation-induced injury in endothelial gap junctional intercellular communication. |
| PubMed:Screening of anti-hypoxia/reoxygenation agents by an in vitro model. Part 1: Natural inhibitors for protein tyrosine kinase activated by hypoxia/reoxygenation in cultured human umbilical vein endothelial cells. |
| PubMed:Determination of icariin in Chinese traditional medicine by capillary zone electrophoresis. |
| PubMed:[Effects of icarrin on secretive function of cultured granulosa and adrenal cortical cells of rats]. |
| PubMed:Isolation and immunomodulatory effect of flavonol glycosides from Epimedium hunanense. |
| PubMed:[Determination of icariin in Epimedium koreanum nakai by high performance liquid chromatography]. |
| PubMed:Characterization of flavonoids in extracts from four species of Epimedium by micellar electrokinetic capillary chromatography with diode-array detection. |
| PubMed:[Effects of icariin on the differentiation of HL-60 cells]. |
| PubMed:Flavonoids from Epimedium wanshanense. |
| PubMed:[Chemical constituents from the whole plant of Epimedium fargesii Franch]. |
| PubMed:[Preparation of huichun zhibao oral liquid (HZOL)]. |
| PubMed:[Quality control of zhuanggu shenjin capsules]. |
| PubMed:Antihepatotoxic activity of icariin, a major constituent of Epimedium koreanum. |
| PubMed:Immunoregulatory effects of the herba Epimediia glycoside icariin. |
| PubMed:[Determination of the content of icariine in four Chinese patent medicines containing Epimedium brevicornum Maxim]. |
| PubMed:[Chemical studies of Epimedium acuminatum Franch]. |
| PubMed:[Studies on dissolution of icariin from wuxian huichun capsules]. |
| PubMed:New tetrasaccharide flavonol glycoside from Epimedium acuminatum. |
| PubMed:Flavonol glycoside production in callus cultures of Epimedium diphyllum. |
| PubMed:Two flavonol glycosides, hexandrasides C and D, from the underground parts of Vancouveria hexandra. |
| PubMed:[Determination of icarim in luohan jindan oral liquid by thin-layer chromatography]. |
| PubMed:[Preparation conditions for decoction of Epimedium grandiflorum Morr]. |
| PubMed:[Phagocytic activity of leaves of Epimedium species on mouse reticuloendotherial system]. |
| PubMed:Determination of total flavonoids in Epimedium brevicornum maxim by differential pulse polarography. |
| PubMed:[Chemical studies of Epimedium wushanense T. S. Ying]. |
3D/inchi