polydatin
3,4',5-trihydroxystilbene-3-b-glucoside
 
Notes:
from polygonum cuspidatum.
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(2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol (Click)
CAS Number: 65914-17-2Picture of molecule
Beilstein Number: 0054837
XlogP3: 1.70 (est)
Molecular Weight: 390.38894000
Formula: C20 H22 O8
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: antioxidants
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 707.70 °C. @ 760.00 mm Hg (est)
Flash Point: 719.00 °F. TCC ( 381.80 °C. ) (est)
logP (o/w): 0.412 (est)
Soluble in:
 water, 1616 mg/L @ 25 °C (est)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
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Suppliers:
Carbosynth
For experimental / research use only.
3,4',5-Trihydroxystilbene-3-b-D-glucopyranoside
ExtraSynthese
For experimental / research use only.
Polydatin (HPLC) ≥99%
Santa Cruz Biotechnology
For experimental / research use only.
Polydatin
Sigma-Aldrich: Sigma
For experimental / research use only.
Polydatin ≥95% (HPLC)
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antioxidants
Recommendation for polydatin usage levels up to:
 not for fragrance use.
 
Recommendation for polydatin flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
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EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 5281718
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
Chemidplus: 0065914172
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References:
 (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 5281718
Pubchem (sid): 135032843
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
HMDB (The Human Metabolome Database): Search
MedlinePlusSupp: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 polygonum cuspidatum
Search Trop  Picture
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Synonyms:
3-hydroxy-5-(p-hydroxystyryl)phenyl glucoside
(2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
3-hydroxy-5-[2-(4-hydroxyphenyl)ethenyl]phenyl-b-D-glucopyranoside
 piceid
 resveratrol-3-b-mono-D-glucoside
3,4',5-trihydroxystilbene-3-b-glucoside
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Articles:
PubMed: [Inhibitory effect of polydatin on expression of toll-like receptor 4 in ischemia-reperfusion injured NRK-52E cells].
PubMed: Polydatin prevents angiotensin II-induced cardiac hypertrophy and myocardial superoxide generation.
PubMed: Polydatin prevents hypertrophy in phenylephrine induced neonatal mouse cardiomyocytes and pressure-overload mouse models.
PubMed: Purification and functional characterization of the first stilbene glucoside-specific β-glucosidase isolated from Lactobacillus kimchi.
PubMed: Pharmacokinetics and bioavailability study of polydatin in rat plasma by using a LC-MS/MS method.
PubMed: Polydatin supplementation ameliorates diet-induced development of insulin resistance and hepatic steatosis in rats.
PubMed: Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway.
PubMed: Protective effect of polydatin on learning and memory impairments in neonatal rats with hypoxic‑ischemic brain injury by up‑regulating brain‑derived neurotrophic factor.
PubMed: Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells.
PubMed: Investigation of the effects of some phenolic compounds on the activities of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from human erythrocytes.
PubMed: Quantitative analysis of ligand effects on bioefficacy of nanoemulsion encapsulating depigmenting active.
PubMed: Protective effect of polydatin, a natural precursor of resveratrol, against cisplatin-induced toxicity in rats.
PubMed: The yeast Wickerhamomyces anomalus AS1 secretes a multifunctional exo-β-1,3-glucanase with implications for winemaking.
PubMed: Polydatin attenuates cardiac hypertrophy through modulation of cardiac Ca2+ handling and calcineurin-NFAT signaling pathway.
PubMed: Protective effect of polydatin against burn-induced lung injury in rats.
PubMed: Optimized ultrasound-assisted extraction of phenolic compounds from Polygonum cuspidatum.
PubMed: Enzymatic transformation of polydatin to resveratrol by piceid-β-D-glucosidase from Aspergillus oryzae.
PubMed: The stilbenes resveratrol, pterostilbene and piceid affect growth and stress resistance in mammalian cells via a mechanism requiring estrogen receptor beta and the induction of Mn-superoxide dismutase.
PubMed: Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest.
PubMed: Resveratrol and piceid metabolites and their fat-reduction effects in zebrafish larvae.
PubMed: Probing the anti-aging role of polydatin in Caenorhabditis elegans on a chip.
PubMed: Characterisation of stilbenes in California almonds (Prunus dulcis) by UHPLC-MS.
PubMed: Membrane permeability-guided identification of neuroprotective components from Polygonum cuspidatun.
PubMed: Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell.
PubMed: Quantitative analysis of tenuifolin concentrations in rat plasma and tissue using LC⬜MS/MS: application to pharmacokinetic and tissue distribution study.
PubMed: [Administration of micronized palmitoylethanolamide (PEA)-transpolydatin in the treatment of chronic pelvic pain in women affected by endometriosis: preliminary results].
PubMed: Highly efficient biotransformation of polydatin to resveratrol by snailase hydrolysis using response surface methodology optimization.
PubMed: Polydatin: a review of pharmacology and pharmacokinetics.
PubMed: Polydatin attenuated food allergy via store-operated calcium channels in mast cell.
PubMed: Validation of HPLC method for the determination of polydatin in giant knotweed rhizome.
PubMed: Enhancement of polydatin on inward rectifier potassium channel current in rat ventricular myocytes.
PubMed: Quality assessment of Japanese knotweed (Fallopia japonica) grown on Prince Edward Island as a source of resveratrol.
PubMed: [Effects of polydatin on ALT, AST, TNF-alpha, and COX-2 in sepsis model mice].
PubMed: Influence of processing on pharmacokinetic of typical constituents in radix polygoni multiflori after oral administration by LC-ESI-MS/MS.
PubMed: Biotransformation of polydatin to resveratrol in Polygonum cuspidatum roots by highly immobilized edible Aspergillus niger and Yeast.
PubMed: Polydatin protects cardiac function against burn injury by inhibiting sarcoplasmic reticulum Ca2+ leak by reducing oxidative modification of ryanodine receptors.
PubMed: Pre-column incubation followed by fast liquid chromatography analysis for rapid screening of natural methylglyoxal scavengers directly from herbal medicines: case study of Polygonum cuspidatum.
PubMed: [Administration of MICRONIZED PALMITOYLETHANOLAMIDE (PEA)-transpolydatin in the treatment of chronic pelvic pain in women affected by endometriosis: preliminary results.]
PubMed: Creation of resveratrol-enriched rice for the treatment of metabolic syndrome and related diseases.
PubMed: [Antioxidant activity constituents from root of Rubus crataegifolius].
PubMed: Protective effects of polydatin on septic lung injury in mice via upregulation of HO-1.
PubMed: The adjuvant use of N-palmitoylethanolamine and transpolydatin in the treatment of endometriotic pain.
PubMed: Vestibulodynia: synergy between palmitoylethanolamide + transpolydatin and transcutaneous electrical nerve stimulation.
PubMed: Comparision of piceid and resveratrol in antioxidation and antiproliferation activities in vitro.
PubMed: Chemical constituents of Caesalpinia decapetala (Roth) Alston.
PubMed: [Active neuraminidase constituents of Polygonum cuspidatum against influenza A(H1N1) influenza virus].
PubMed: Polydatin protects against lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine-sensitized mice.
PubMed: Stilbenoid profiles of canes from Vitis and Muscadinia species.
PubMed: Polydatin--a new mitochondria protector for acute severe hemorrhagic shock treatment.
PubMed: Bioconversion of piceid to piceid glucoside using amylosucrase from Alteromonas macleodii deep ecotype.
PubMed: Modulation of human keratinocyte responses to solar UV by plant polyphenols as a basis for chemoprevention of non-melanoma skin cancers.
PubMed: Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose-induced urate nephropathic mice.
PubMed: Analysis and functionality of major polyphenolic components of Polygonum cuspidatum (itadori).
PubMed: Differential cell-protective function of two resveratrol (trans-3,5,4'-trihydroxystilbene) glucosides against oxidative stress.
PubMed: Protective effects of polydatin from Polygonum cuspidatum against carbon tetrachloride-induced liver injury in mice.
PubMed: [Simultaneous determination of contents of five major bioactive components contained in Polygoni Cuspidati Rhizoma et Radix by microwave extraction-ultra performance liquid chromatography].
PubMed: Polydatin (PD) inhibits IgE-mediated passive cutaneous anaphylaxis in mice by stabilizing mast cells through modulating Ca²⁺ mobilization.
PubMed: Polydatin, a natural precursor of resveratrol, induces β-defensin production and reduces inflammatory response.
PubMed: The progress of the research on cardio-vascular effects and acting mechanism of polydatin.
PubMed: Polydatin modulates Ca(2+) handling, excitation-contraction coupling and β-adrenergic signaling in rat ventricular myocytes.
PubMed: Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets.
PubMed: Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice.
PubMed: Polydatin alleviates non-alcoholic fatty liver disease in rats by inhibiting the expression of TNF-α and SREBP-1c.
PubMed: Polydatin Attenuates Hypoxic Pulmonary Hypertension and Reverses Remodeling through Protein Kinase C Mechanisms.
PubMed: Enzymatic synthesis of piceid glucosides using maltosyltransferase from Caldicellulosiruptor bescii DSM 6725.
PubMed: [Effect of polydatin on expression of cdk5 in the prefrontal cortex of rats with chronic alcoholism].
PubMed: Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-κB signaling pathway in rat glomerular mesangial cells.
PubMed: Multiparameter evaluation of the longevity in C. elegans under stress using an integrated microfluidic device.
PubMed: Polydatin protects learning and memory impairments in a rat model of vascular dementia.
PubMed: Polydatin suppresses ultraviolet B-induced cyclooxygenase-2 expression in vitro and in vivo via reduced production of reactive oxygen species.
PubMed: Separation and identification of highly fluorescent compounds derived from trans-resveratrol in the leaves of Vitis vinifera infected by Plasmopara viticola.
PubMed: [Effects of polydatin on bleomycin-induced pulmonary fibrosis in rats].
PubMed: Liquid chromatography/tandem mass spectrometry method for quantification of trans-stilbene glycoside in rat plasma and its pharmacokinetic application.
PubMed: Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock.
PubMed: An optimum fermentation model established by genetic algorithm for biotransformation from crude polydatin to resveratrol.
PubMed: Polydatin modulates inflammation by decreasing NF-κB activation and oxidative stress by increasing Gli1, Ptch1, SOD1 expression and ameliorates blood-brain barrier permeability for its neuroprotective effect in pMCAO rat brain.
PubMed: Plant polyphenols regulate chemokine expression and tissue repair in human keratinocytes through interaction with cytoplasmic and nuclear components of epidermal growth factor receptor system.
PubMed: [Effect of polydatin on learning and memory and expression of NR2B in the prefrontal cortex of rats with chronic alcoholism].
PubMed: Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to polydatin-induced apoptosis in human nasopharyngeal carcinoma CNE cells.
PubMed: Cardioprotective effect of polydatin against ischemia/reperfusion injury: roles of protein kinase C and mito K(ATP) activation.
PubMed: Polydatin up-regulates Clara cell secretory protein to suppress phospholipase A2 of lung induced by LPS in vivo and in vitro.
PubMed: Plant polyphenols differentially modulate inflammatory responses of human keratinocytes by interfering with activation of transcription factors NFκB and AhR and EGFR-ERK pathway.
PubMed: Study on the structural changes of bovine serum albumin with effects on polydatin binding by a multitechnique approach.
PubMed: Overexpression of a resveratrol synthase gene (PcRS) from Polygonum cuspidatum in transgenic Arabidopsis causes the accumulation of trans-piceid with antifungal activity.
PubMed: Separation of polyphenols using porous polyamide resin and assessment of mechanism of retention.
PubMed: Effect of ZnO#ZnS QDs heterojunctures on the stilbenes-plasma proteins interactions.
PubMed: Effectiveness of the association micronized N-Palmitoylethanolamine (PEA)-transpolydatin in the treatment of chronic pelvic pain related to endometriosis after laparoscopic assessment: a pilot study.
PubMed: Simultaneous analysis of serotonin, melatonin, piceid and resveratrol in fruits using liquid chromatography tandem mass spectrometry.
PubMed: [Optimization of ultrahigh pressure extraction for polydatin and resveratrol from Polygonum cuspidatum by using uniform design].
PubMed: An automatic optosensing device for the simultaneous determination of resveratrol and piceid in wines.
PubMed: Anti-inflammatory effect of resveratrol and polydatin by in vitro IL-17 modulation.
PubMed: [Effect of polydatin on dynamic changes of excitatory amino acids in cerebrospinal fluid of cerebral hemorrhage rats].
PubMed: Effect of polydatin on action potential in ventricular papillary muscle of rat and the underlying ionic mechanism.
PubMed: Determination of resveratrol and piceid in beer matrices by solid-phase extraction and liquid chromatography-tandem mass spectrometry.
PubMed: [Studies on the chemical constituents of radix Boehmeriae].
PubMed: Investigation of piceid metabolites in rat by liquid chromatography tandem mass spectrometry.
PubMed: Polydatin ameliorates DSS-induced colitis in mice through inhibition of nuclear factor-kappaB activation.
PubMed: Automatic optosensing device based on photo-induced fluorescence for determination of piceid in cocoa-containing products.
PubMed: Inhibition of melanogenesis by piceid isolated from Polygonum cuspidatum.
PubMed: Sensitized synchronous fluorimetric determination of trans-resveratrol and trans-piceid in red wine based on their immobilization on nylon membranes.
PubMed: Inhibition of TNF-α-mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,4'-trimethoxystilbene.
PubMed: Effects of polydatin on attenuating ventricular remodeling in isoproterenol-induced mouse and pressure-overload rat models.
PubMed: Electrospray ionization mass spectrometry probing of formation and recognition of the G-quadruplex in the proximal promoter of the human vascular endothelial growth factor gene.
PubMed: [Protective effect of polydatin on a PC12 cell model of oxygen-glucose deprivation].
PubMed: Bioactivity-guided separation of anti-acidogenic substances against Streptococcus mutans UA 159 from Polygonum cuspidatum.
PubMed: Evolution of resveratrol and piceid contents during the industrial winemaking process of sherry wine.
PubMed: Quantitative structure-antioxidant activity relationship of trans-resveratrol oligomers, trans-4,4'-dihydroxystilbene dimer, trans-resveratrol-3-O-glucuronide, glucosides: trans-piceid, cis-piceid, trans-astringin and trans-resveratrol-4'-O-beta-D-glucopyranoside.
PubMed: Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations.
PubMed: Cre-mediated seed-specific transgene excision in tobacco.
PubMed: Hypotensive resuscitation combined with polydatin improve microcirculation and survival in a rabbit model of uncontrolled hemorrhagic shock in pregnancy.
PubMed: [Identification and determination of major constituents in Polygonum cuspidatum Sieb. et Zucc. by high performance liquid chromatography/electrospray ionization-ion trap-time-of-flight mass spectrometry].
PubMed: [Pharmacokinetic study of polydatin in Beagle dogs].
PubMed: Polydatin attenuates ischemia/reperfusion-induced apoptosis in myocardium of the rat.
PubMed: Effect of ultraviolet doses in combined ultraviolet-ultrasound treatments on trans-resveratrol and trans-piceid contents in sliced peanut kernels.
PubMed: Implication of signaling pathways involving calcium, phosphorylation and active oxygen species in methyl jasmonate-induced defense responses in grapevine cell cultures.
PubMed: Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci.
PubMed: Dose-dependent absorption and metabolism of trans-polydatin in rats.
PubMed: [Studies on chemical constituents from leaves of Lysidice brevicalyx].
PubMed: [The regulative effects of polydatin on toll-like receptor 4 signal transduction pathway in lung ischemia/reperfusion injury in rabbits].
PubMed: Functional characterization of a stilbene synthase gene using a transient expression system in planta.
PubMed: Lipid-lowering effects of polydatin from Polygonum cuspidatum in hyperlipidemic hamsters.
PubMed: The polyphenol piceid destabilizes preformed amyloid fibrils and oligomers in vitro: hypothesis on possible molecular mechanisms.
PubMed: Direct determination of polydatin and its metabolite in rat excrement samples by high-performance liquid chromatography.
PubMed: Targeted isolation and structure elucidation of stilbene glycosides from the bark of Lysidice brevicalyx Wei guided by biological and chemical screening.
PubMed: Survey of the trans-resveratrol and trans-piceid content of cocoa-containing and chocolate products.
PubMed: Microwave-assisted aqueous two-phase extraction of piceid, resveratrol and emodin from Polygonum cuspidatum by ethanol/ammonium sulphate systems.
PubMed: Effects of polydatin from Polygonum cuspidatum on lipid profile in hyperlipidemic rabbits.
PubMed: Analysis of selected stilbenes in Polygonum cuspidatum by HPLC coupled with CoulArray detection.
PubMed: [Effect of assorted use of Chinese drugs for detoxifying and activating blood circulation on serum high sensitive C-reactive protein in apolipoprotein E gene knock-out mice].
PubMed: Influence of pressing method on juice stilbene content in muscadine and bunch grapes.
PubMed: Protective effect of polydatin against ischemia/reperfusion injury in rat heart.
PubMed: Antioxidant properties of resveratrol and piceid on lipid peroxidation in micelles and monolamellar liposomes.
PubMed: [Protective effects of polydatin against lung ischemia/reperfusion injury and the initial exploration for its mechanism].
PubMed: Simultaneous identification and quantification of anthraquinones, polydatin, and resveratrol in Polygonum multiflorum, various Polygonum species, and dietary supplements by liquid chromatography and microscopic study of Polygonum species.
PubMed: Fate of resveratrol and piceid through different hop processings and storage times.
PubMed: [Study on correlation of soil nutrients and content of active constituents in root of Rumex gmelini].
PubMed: Concentrations of resveratrol and derivatives in foods and estimation of dietary intake in a Spanish population: European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain cohort.
PubMed: Optimization and validation of a chromatographic method for the simultaneous quantification of six bioactive compounds in Rhizoma et Radix Polygoni Cuspidati.
PubMed: Isocratic chromatography of resveratrol and piceid after previous generation of fluorescent photoproducts: wine analysis without sample preparation.
PubMed: [Increasing the content of active constituents in Polygonum cuspidatum hairy root by gene transformation technology].
PubMed: [Biological dressing with human hair keratin-collagen sponge-poly 2-hydroxyethyl methacrylate composite promotes burn wound healing in SD rats].
PubMed: Accumulation of trans-piceid in sorghum seedlings infected with Colletotrichum sublineolum.
PubMed: Occurrence of resveratrol and piceid in American and European hop cones.
PubMed: [Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues].
PubMed: [Application of macroporous resin in purification for effective part from Polygonum cuspidatum].
PubMed: Quantitative determination of trans-polydatin, a natural strong anti-oxidative compound, in rat plasma and cellular environment of a human colon adenocarcinoma cell line for pharmacokinetic studies.
PubMed: Transgenic alfalfa that accumulates piceid (trans-resveratrol-3-O-beta-D-glucopyranoside) requires the presence of beta-glucosidase to inhibit the formation of aberrant crypt foci in the colon of CF-1 mice.
PubMed: Biotransformation of piceid in Polygonum cuspidatum to resveratrol by Aspergillus oryzae.
PubMed: [Regulatory effect of Chinese herbal compound for detoxifying and activating blood circulation on expression of NF-kappaB and MMP-9 in aorta of apolipoprotein E gene knocked-out mice].
PubMed: [HPLC fingerprint of Rhizoma Polygoni Cuspidati].
PubMed: Transport, deglycosylation, and metabolism of trans-piceid by small intestinal epithelial cells.
PubMed: [Quantitative determination of the (E) - and (Z) -diastereomers of resveratrol and resveratrol glucoside in the roots of Polygonum cuspidatum by HPLC and elementary study on their fluorescence].
PubMed: [Effects of light intensity on resveratrol and polydatin production in Rumex gmelini root].
PubMed: Determination of piceid in rat plasma and tissues by high-performance liquid chromatographic method with UV detection.
PubMed: Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia-reperfusion injury.
PubMed: [Contents comparison of resveratrol and polydatin in the wild Polygonum cuspidatum plant and its tissue cultures].
PubMed: Piceid (resveratrol glucoside) synthesis in stilbene synthase transgenic apple fruit.
PubMed: Constitutive accumulation of cis-piceid in transgenic Arabidopsis overexpressing a sorghum stilbene synthase gene.
PubMed: Resveratrol and its glycon piceid are stable polyphenols.
PubMed: Antioxidant activity and inhibition of alpha-glucosidase by trans-resveratrol, piceid, and a novel trans-stilbene from the roots of Israeli Rumex bucephalophorus L.
PubMed: HPLC determination of polydatin in rat biological matrices: application to pharmacokinetic studies.
PubMed: Hemorheologic events in severe shock.
PubMed: Preparative isolation and purification of five compounds from the Chinese medicinal herb Polygonum cuspidatum Sieb. et Zucc by high-speed counter-current chromatography.
PubMed: Role of peptide primary sequence in polyphenol-protein recognition: an example with neurotensin.
PubMed: A validated HPLC method for the quantitative analysis of trans-resveratrol and trans-piceid in Hungarian wines.
PubMed: Resveratrol glucoside (Piceid) synthesis in seeds of transgenic oilseed rape (Brassica napus L.).
PubMed: [Study on the optimal harvesting time of Rumex gmelini by analyzing the contents of principal components].
PubMed: Simple and rapid method for cis- and trans-resveratrol and piceid isomers determination in wine by high-performance liquid chromatography using chromolith columns.
PubMed: Determination of stilbenes (delta-viniferin, trans-astringin, trans-piceid, cis- and trans-resveratrol, epsilon-viniferin) in Brazilian wines.
PubMed: Determination of stilbenes in hop pellets from different cultivars.
PubMed: Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells.
PubMed: Inhibiting effects of resveratrol and its glucoside piceid against Venturia inaequalis, the causal agent of apple scab.
PubMed: Vasodilator constituents from the roots of Lysidice rhodostega.
PubMed: Expression of the stilbene synthase (StSy) gene from grapevine in transgenic white poplar results in high accumulation of the antioxidant resveratrol glucosides.
PubMed: Determination of piceid and resveratrol in Spanish wines deriving from Monastrell (Vitis vinifera L.) grape variety.
PubMed: Effect of polydatin on phospholipase A2 in lung tissues in rats with endotoxic shock.
PubMed: Antioxidants in Sicilian wines: analytic and compositive aspects.
PubMed: The mechanism of Polydatin in shock treatment.
PubMed: [Effect of polydatin on lipopolysaccharide-induced leucocyte chemotaxis].
PubMed: Pharmacological studies on resveratrol.
PubMed: [Determination of piceid in commercial Rhizoma Polygoni Cuspidati by HPLC].
PubMed: Protective effect of polydatin against lipopolysaccharide-induced myocardial injury.
PubMed: [Progress in the pharmacological study of Chinese herbal drug: polygonum cuspidatum].
PubMed: Capillary electrophoresis determination, synthesis, and stability of resveratrol and related 3-O-beta-D-glucopyranosides.
PubMed: Induction of apoptosis by 3,4'-dimethoxy-5-hydroxystilbene in human promyeloid leukemic HL-60 cells.
PubMed: Protective effects of polydatin against CCl(4)-induced injury to primarily cultured rat hepatocytes.
PubMed: Resveratrol and piceid levels in natural and blended peanut butters.
PubMed: High-speed counter-current chromatography separation and purification of resveratrol and piceid from Polygonum cuspidatum.
PubMed: Method for the quantitative extraction of resveratrol and piceid isomers in grape berry skins. Effect of powdery mildew on the stilbene content.
PubMed: A stilbene and dihydrochalcones with radical scavenging activities from Loiseleuria procumbens.
PubMed: Oligostilbenoids in stem bark of Vatica rassak.
PubMed: Piceid, the major resveratrol derivative in grape juices.
PubMed: Biotransformation of resveratrol to piceid by Bacillus cereus.
PubMed: Contents of resveratrol, piceid, and their isomers in commercially available wines made from grapes cultivated in Japan.
PubMed: A multiresidue derivatization gas chromatographic assay for fifteen phenolic constituents with mass selective detection.
PubMed: Wine as a biological fluid: history, production, and role in disease prevention.
PubMed: Influence of 3,4',5-trihydroxystibene-3-beta-mono-D-glucoside on vascular endothelial epoprostenol and platelet aggregation.
PubMed: Reducing effect of 3,4',5-trihydroxystibene-3-beta-mono-D-glucoside on arterial thrombosis induced by vascular endothelial injury.
PubMed: [Polydatin prevents endotoxin-induced acute lung injury in rats].
PubMed: [Pharmacological intervention in experimental multiple organ failure in rats].
PubMed: [Influences of 3,4,5-trihydroxystibene-3-beta-mono-D-glucoside on rabbits' platelet aggregation and thromboxane B2 production in vitro].
PubMed: [Influences of 3,4,5-trihydroxystibene-3-beta-mono-D-glucoside on beat rate and injury of cultured newborn rat myocardial cells].
PubMed: [Effects of polydatin on platelet aggregation in rabbits].
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