| PubMed:Glycation is regulated by isoflavones. |
| PubMed:Soy Isoflavones for Reducing Bone Loss Study: effects of a 3-year trial on hormones, adverse events, and endometrial thickness in postmenopausal women. |
| PubMed:Conversion of major soy isoflavone glucosides and aglycones in in vitro intestinal models. |
| PubMed:Soy isoflavone: The multipurpose phytochemical (Review). |
| PubMed:Oxidative metabolism enhances the cytotoxic and genotoxic properties of the soy isoflavone daidzein. |
| PubMed:High concentrations of genistein exhibit pro-oxidant effects in primary muscle cells through mechanisms involving 5-lipoxygenase-mediated production of reactive oxygen species. |
| PubMed:S-(-)equol producing status not associated with breast cancer risk among low isoflavone-consuming US postmenopausal women undergoing a physician-recommended breast biopsy. |
| PubMed:Pharmacokinetics of equol, a soy isoflavone metabolite, changes with the form of equol (dietary versus intestinal production) in ovariectomized rats. |
| PubMed:Effects of short-term fructooligosaccharide intake on equol production in Japanese postmenopausal women consuming soy isoflavone supplements: a pilot study. |
| PubMed:Probiotic Beverage with Soy Isoflavone Consumption for Breast Cancer Prevention: A Case-control Study. |
| PubMed:Soy and its isoflavones: the truth behind the science in breast cancer. |
| PubMed:Inhibitory effects of a major soy isoflavone, genistein, on human DNA topoisomerase II activity and cancer cell proliferation. |
| PubMed:Possible role of S-equol on bone loss via amelioration of inflammatory indices in ovariectomized mice. |
| PubMed:Combination of low dose of genistein and daidzein has synergistic preventive effects on isogenic human prostate cancer cells when compared with individual soy isoflavone. |
| PubMed:Pharmacological administration of the isoflavone daidzein enhances cell proliferation and reduces high fat diet-induced apoptosis and gliosis in the rat hippocampus. |
| PubMed:Soy isoflavones and breast cancer. |
| PubMed:Activation of AMP-activated protein kinase alleviates homocysteine-mediated neurotoxicity in SH-SY5Y cells. |
| PubMed:Self-reported menopausal symptoms in a racially diverse population and soy food consumption. |
| PubMed:Soy isoflavone intake and breast cancer risk in Japan: from the Takayama study. |
| PubMed:[Effects of soy isoflavone on the reproductive system development and ER-beta expression in male rat offspring in different postnatal periods]. |
| PubMed:Soy isoflavone attenuates brain mitochondrial oxidative stress induced by β-amyloid peptides 1-42 injection in lateral cerebral ventricle. |
| PubMed:Daidzein-estrogen interaction in the rat uterus and its effect on human breast cancer cell growth. |
| PubMed:[Effects of soybean isoflavone on reproductive development in SD rats]. |
| PubMed:Effects of dietary genistein on hormone-dependent rat mammary carcinogenesis induced by ethyl methanesulphonate. |
| PubMed:Anti-diabetic functions of soy isoflavone genistein: mechanisms underlying its effects on pancreatic β-cell function. |
| PubMed:Dose-dependent effects of a genistein-enriched diet in the heart of ovariectomized mice. |
| PubMed:Formation of phosphoglycosides in Caenorhabditis elegans: a novel biotransformation pathway. |
| PubMed:Soy products in the management of breast cancer. |
| PubMed:Urinary isoflavonoids and risk of coronary heart disease. |
| PubMed:The soybean peptide lunasin promotes apoptosis of mammary epithelial cells via induction of tumor suppressor PTEN: similarities and distinct actions from soy isoflavone genistein. |
| PubMed:Effects of estrogen and estrus cycle on pharmacokinetics, absorption, and disposition of genistein in female Sprague-Dawley rats. |
| PubMed:Impact of food matrix on isoflavone metabolism and cardiovascular biomarkers in adults with hypercholesterolemia. |
| PubMed:Phytoestrogens genistein and daidzein affect immunity in the nematode Caenorhabditis elegans via alterations of vitellogenin expression. |
| PubMed:Glyceollins, soy isoflavone phytoalexins, improve oral glucose disposal by stimulating glucose uptake. |
| PubMed:Soy food intake after diagnosis of breast cancer and survival: an in-depth analysis of combined evidence from cohort studies of US and Chinese women. |
| PubMed:Study on soy isoflavone consumption and risk of breast cancer and survival. |
| PubMed:Optimization of soy isoflavone extraction with different solvents using the simplex-centroid mixture design. |
| PubMed:Positive effects of soy isoflavone food on survival of breast cancer patients in China. |
| PubMed:Determination of 15 isoflavone isomers in soy foods and supplements by high-performance liquid chromatography. |
| PubMed:Separation of soybean isoflavone aglycone homologues by ionic liquid-based extraction. |
| PubMed:In utero and lactational exposure to low-dose genistein-vinclozolin mixture affects the development and growth factor mRNA expression of the submandibular salivary gland in immature female rats. |
| PubMed:[Equol-producing phenotype and in relation to serum sex hormones among healthy adults in Beijing]. |
| PubMed:Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39. |
| PubMed:Epigenetic modifications of metastasis suppressor genes in colon cancer metastasis. |
| PubMed:Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and L-carnitine: implications in cardiovascular and non-alcoholic fatty liver diseases. |
| PubMed:Effect of soy isoflavones on circulating C-reactive protein in postmenopausal women: meta-analysis of randomized controlled trials. |
| PubMed:Effects of S-equol and natural S-equol supplement (SE5-OH) on the growth of MCF-7 in vitro and as tumors implanted into ovariectomized athymic mice. |
| PubMed:[Changes of serum lipids after soy isoflavone and calcium supplementation in postmenopausal Chinese women with different ER-beta genotypes]. |
| PubMed:The role of soy isoflavones in menopausal health: report of The North American Menopause Society/Wulf H. Utian Translational Science Symposium in Chicago, IL (October 2010). |
| PubMed:Genistein selectively inhibits estrogen-induced cell proliferation and other responses to hormone stimulation in the prepubertal rat uterus. |
| PubMed:Soy isoflavone genistein induces cell death in breast cancer cells through mobilization of endogenous copper ions and generation of reactive oxygen species. |
| PubMed:Single-dose and steady-state pharmacokinetic studies of S-equol, a potent nonhormonal, estrogen receptor β-agonist being developed for the treatment of menopausal symptoms. |
| PubMed:Effect of free or protein-associated soy isoflavones on the antioxidant status in rats. |
| PubMed:Relationship between soy food intake and breast cancer in China. |
| PubMed:Estrogen receptor-β mediates the inhibition of DLD-1 human colon adenocarcinoma cells by soy isoflavones. |
| PubMed:Micro total bioassay system for ingested substances: assessment of intestinal absorption, hepatic metabolism, and bioactivity. |
| PubMed:Acute and subchronic toxicity of FCD, a soybean extract combined with L-carnitine, in Sprague-Dawley rats. |
| PubMed:Combined effects of soy isoflavone and fish oil on ovariectomy-induced bone loss in mice. |
| PubMed:Bioavailability of soy isoflavones through placental/lactational transfer and soy food. |
| PubMed:Effect of soy isoflavones on breast cancer recurrence and death for patients receiving adjuvant endocrine therapy. |
| PubMed:Mammary gland differentiation by early life exposure to enantiomers of the soy isoflavone metabolite equol. |
| PubMed:The antioxidant effects of genistein are associated with AMP-activated protein kinase activation and PTEN induction in prostate cancer cells. |
| PubMed:Genistein aglycone: a dual mode of action anti-osteoporotic soy isoflavone rebalancing bone turnover towards bone formation. |
| PubMed:Polymorphic catechol-O-methyltransferase gene, soy isoflavone intake and breast cancer in postmenopausal women: a case-control study. |
| PubMed:PTEN and p53 cross-regulation induced by soy isoflavone genistein promotes mammary epithelial cell cycle arrest and lobuloalveolar differentiation. |
| PubMed:Enhancing the biotransformation of isoflavones in soymilk supplemented with lactose using probiotic bacteria during extended fermentation. |
| PubMed:Soy isoflavone and its effect to regulate hypothalamus and peripheral orexigenic gene expression in ovariectomized rats fed on a high-fat diet. |
| PubMed:Effects of surfactant and salt species in reverse micellar forward extraction efficiency of isoflavones with enriched protein from soy flour. |
| PubMed:Inhibition by genistein of the lipopolysaccharide-induced down-regulation of programmed cell death 4 in RAW 264.7 mouse macrophages. |
| PubMed:[Prevalence of equol producer phenotype and its relations to lifestyle factors and dietary intakes among lifestyle factors and dietary intakes among healthy Chinese adults in Beijing]. |
| PubMed:[Relationship between dietary soy isoflavones and blood lipid levels in 40 - 65 year-olds in Guangzhou]. |
| PubMed:Factors to consider in the association between soy isoflavone intake and breast cancer risk. |
| PubMed:Extraction methods determine the antioxidant capacity and induction of quinone reductase by soy products in vitro. |
| PubMed:Soy food intake and breast cancer survival. |
| PubMed:Impact of dietary genistein and aging on executive function in rats. |
| PubMed:The soy isoflavones for reducing bone loss (SIRBL) study: a 3-y randomized controlled trial in postmenopausal women. |
| PubMed:Soy product and isoflavone intake and breast cancer risk defined by hormone receptor status. |
| PubMed:Cellular DNA breakage by soy isoflavone genistein and its methylated structural analogue biochanin A. |
| PubMed:Efficacy of isoflavones in relieving vasomotor menopausal symptoms - A systematic review. |
| PubMed:Isoflavonoid content of Hong Kong soy foods. |
| PubMed:Early soy exposure via maternal diet regulates rat mammary epithelial differentiation by paracrine signaling from stromal adipocytes. |
| PubMed:Soy isoflavones and risk of cancer recurrence in a cohort of breast cancer survivors: the Life After Cancer Epidemiology study. |
| PubMed:Soy isoflavones modulate azoxymethane-induced rat colon carcinogenesis exposed pre- and postnatally and inhibit growth of DLD-1 human colon adenocarcinoma cells by increasing the expression of estrogen receptor-beta. |
| PubMed:Soybean and soy isoflavone intake indicate a positive change in bone mineral density for 2 years in young Korean women. |
| PubMed:[Relationship between estrogen receptor gene Px haplotype and the effect of calcium and soy isoflavone supplementation on bone mineral density of Chinese postmenopausal women]. |
| PubMed:Soy food and isoflavone intake in relation to semen quality parameters among men from an infertility clinic. |
| PubMed:Synthesis of haptens and conjugates for ELISA of glycitein: development and validation of an immunological test. |
| PubMed:Dietary genistein negates the inhibitory effect of letrozole on the growth of aromatase-expressing estrogen-dependent human breast cancer cells (MCF-7Ca) in vivo. |
| PubMed:Effects of isoflavone supplements vs. soy foods on blood concentrations of genistein and daidzein in adults. |
| PubMed:Soy intake and breast cancer risk in Singapore Chinese Health Study. |
| PubMed:Dose-response assessment of the anti-cancer efficacy of soy isoflavones in dimethylhydrazine-treated rats fed 6% fructooligosaccharide. |
| PubMed:The combination of genistin and ipriflavone prevents mammary tumorigenesis and modulates lipid profile. |
| PubMed:The key importance of soy isoflavone bioavailability to understanding health benefits. |
| PubMed:Determination of total soy isoflavones in dietary supplements, supplement ingredients, and soy foods by high-performance liquid chromatography with ultraviolet detection: collaborative study. |
| PubMed:Development of techniques for the analysis of isoflavones in soy foods and nutraceuticals. |
| PubMed:Fructooligosaccharide and soy isoflavone suppress colonic aberrant crypt foci and cyclooxygenase-2 expression in dimethylhydrazine-treated rats. |
| PubMed:Long-term effects of phytoestrogen daidzein on penile cavernosal structures in adult rats. |
| PubMed:Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: a randomized, double-blind, placebo controlled study. |
| PubMed:Demographic, anthropometric, and lifestyle factors and dietary intakes in relation to daidzein-metabolizing phenotypes among premenopausal women in the United States. |
| PubMed:Puma is a novel target of soy isoflavone genistein but is dispensable for genistein-induced cell fate determination. |
| PubMed:Validation of a food frequency questionnaire for assessing dietary soy isoflavone intake among midlife Chinese women in Hong Kong. |
| PubMed:Dietary soy isoflavone-aglycone lowers food intake in female rats with and without ovariectomy. |
| PubMed:Epidemiology of soy exposures and breast cancer risk. |
| PubMed:A combination of soy isoflavone supplementation and exercise improves lipid profiles and protects antioxidant defense-systems against exercise-induced oxidative stress in ovariectomized rats. |
| PubMed:Effects of lactational exposure to soy isoflavones on reproductive system in neonatal female rats. |
| PubMed:Increased expression of catalase in human hepatoma cells by the soy isoflavone, daidzein. |
| PubMed:Proteomic biomarkers of peripheral blood mononuclear cells obtained from postmenopausal women undergoing an intervention with soy isoflavones. |
| PubMed:Dietary sources and determinants of soy isoflavone intake among midlife Chinese Women in Hong Kong. |
| PubMed:Isoflavone intake in persons at high risk of cardiovascular events: implications for vascular endothelial function and the carotid atherosclerotic burden. |
| PubMed:Studies on the anti-tumor activities of the soy isoflavone daidzein on murine neuroblastoma cells. |
| PubMed:Interaction of soy food and tea consumption with CYP19A1 genetic polymorphisms in the development of endometrial cancer. |
| PubMed:Effect of daidzein, a soy isoflavone, on bone metabolism in Cd-treated ovariectomized rats. |
| PubMed:Age-related uterotrophic response of soy isoflavone intake in rats. |
| PubMed:Plasma levels of genistein following a single dose of soy extract capsule in Indian women. |
| PubMed:In vitro and in vivo metabolism of the soy isoflavone glycitein. |
| PubMed:Oral intake of soy isoflavone aglycone improves the aged skin of adult women. |
| PubMed:Associations between soy, diet, reproductive factors, and mammographic density in Singapore Chinese women. |
| PubMed:Quercetin-induced PC12 cell death accompanied by caspase-mediated DNA fragmentation. |
| PubMed:Dietary lignan intake and postmenopausal breast cancer risk by estrogen and progesterone receptor status. |
| PubMed:Interaction of soy and 17beta-HSD1 gene polymorphisms in the risk of endometrial cancer. |
| PubMed:Effect of genistein with carnitine administration on lipid parameters and obesity in C57Bl/6J mice fed a high-fat diet. |
| PubMed:Enhanced estrogenic responses and sensitivity to azoxymethane following dietary soy isoflavone supplementation in older female rats. |
| PubMed:[Effects of soy isoflavone on levels of low-grade inflammatory peptides in rats with insulin resistance]. |
| PubMed:[Effects of soy isoflavone on gene expression of resistin in insulin-resistance rats]. |
| PubMed:[Prevention of osteoporosis by foods and dietary supplements. "Daizuga-cha", Kuromame-cha"]. |
| PubMed:Phytoestrogens as bioactive ingredients in functional foods: Canadian regulatory update. |
| PubMed:Equol: a comparison of the effects of the racemic compound with that of the purified S-enantiomer on the growth, invasion, and DNA integrity of breast and prostate cells in vitro. |
| PubMed:Genistein protects prostate cells against hydrogen peroxide-induced DNA damage and induces expression of genes involved in the defence against oxidative stress. |
| PubMed:Intake of dietary soy isoflavones in relation to perimenstrual symptoms of Korean women living in the USA. |
| PubMed:Oncogenicity evaluations of chemopreventive soy components in p53((+/-)) (p53 knockout) mice. |
| PubMed:[Effect of soy isoflavone on gene expression of leptin and insulin sensibility in insulin-resistant rats]. |
| PubMed:Prevalence of daidzein-metabolizing phenotypes differs between Caucasian and Korean American women and girls. |
| PubMed:[Effects of soy isoflavone on gene expression of adiponectin in insulin-resistance rats induced by high-fat and high-sugar diet]. |
| PubMed:Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol production. |
| PubMed:Menopause: a review of botanical dietary supplements. |
| PubMed:Effects of soy isoflavone and/or estrogen treatments on bone metabolism in ovariectomized rats. |
| PubMed:Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: a possible mechanism of the growth inhibitory effect of Genistein. |
| PubMed:Genistein enhances N-nitrosomethylurea-induced rat mammary tumorigenesis. |
| PubMed:Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production. |
| PubMed:Soy isoflavone supplementation alleviates oxidative stress and improves systolic blood pressure in male spontaneously hypertensive rats. |
| PubMed:Characterization and quantification of soy isoflavone metabolites in serum of renal transplanted patients by high-performance liquid chromatography/electrospray ionization mass spectrometry. |
| PubMed:Lactational transfer of the soy isoflavone, genistein, in Sprague-Dawley rats consuming dietary genistein. |
| PubMed:Metabolism of glycitein (7,4'-dihydroxy-6-methoxy-isoflavone) by human gut microflora. |
| PubMed:Structural elucidation of hydroxylated metabolites of the isoflavan equol by gas chromatography-mass spectrometry and high-performance liquid chromatography-mass spectrometry. |
| PubMed:Effects of dietary genistein on mouse reproduction, postnatal development and weight-regulation. |
| PubMed:Soy isoflavones and cognitive function. |
| PubMed:Estrogenic and genotoxic potential of equol and two hydroxylated metabolites of Daidzein in cultured human Ishikawa cells. |
| PubMed:Genistein blocks homocysteine-induced alterations in the proteome of human endothelial cells. |
| PubMed:Long-term dietary habits affect soy isoflavone metabolism and accumulation in prostatic fluid in caucasian men. |
| PubMed:Dynamic profiling of estrogen receptor and epidermal growth factor signaling in the uteri of genistein- and estrogen-treated rats. |
| PubMed:Antioxidant properties of soybean isoflavone extract and tofu in vitro and in vivo. |
| PubMed:The effect of soy consumption on the urinary 2:16-hydroxyestrone ratio in postmenopausal women depends on equol production status but is not influenced by probiotic consumption. |
| PubMed:Genistein, a soy isoflavone, enhances necrotic-like cell death in a breast cancer cell treated with a chemotherapeutic agent. |
| PubMed:Quality, labeling accuracy, and cost comparison of purified soy isoflavonoid products. |
| PubMed:Soy isoflavones modify liver free radical scavenger systems and liver parameters in Sprague-Dawley rats. |
| PubMed:Dietary intake of soy genistein is associated with lung function in patients with asthma. |
| PubMed:A simple method for the characterization and quantification of soy isoflavone metabolites in the serum of MMTV-Neu mice using high-performance liquid chromatography/electrospray ionization mass spectrometry with multiple reaction monitoring. |
| PubMed:Anticancer therapeutic potential of soy isoflavone, genistein. |
| PubMed:Soy isoflavone phyto-pharmaceuticals in interleukin-6 affections. Multi-purpose nutraceuticals at the crossroad of hormone replacement, anti-cancer and anti-inflammatory therapy. |
| PubMed:Combined intervention of soy isoflavone and moderate exercise prevents body fat elevation and bone loss in ovariectomized mice. |
| PubMed:Intake of soy foods and soy isoflavones by rural adult women in China. |
| PubMed:Fructooligosaccharides maximize bone-sparing effects of soy isoflavone-enriched diet in the ovariectomized rat. |
| PubMed:LC/UV/ESI-MS analysis of isoflavones in Edamame and Tofu soybeans. |
| PubMed:Lack of an inducible effect of dietary soy isoflavones on the mRNA abundance of hepatic cytochrome P-450 isozymes in rats. |
| PubMed:Regulative actions of dietary soy isoflavone on biological antioxidative system and lipid metabolism in rats. |
| PubMed:Screening for oestrogenic activity of plant and food extracts using in vitro trout hepatocyte cultures. |
| PubMed:Genistein may prevent cadmium-induced bone loss in ovariectomized rats. |
| PubMed:Inhibition of reactive nitrogen species effects in vitro and in vivo by isoflavones and soy-based food extracts. |
| PubMed:Plasma isoflavone levels versus self-reported soy isoflavone levels in Asian-American women in Los Angeles County. |
| PubMed:Dietary soy and fats in relation to serum insulin-like growth factor-1 and insulin-like growth factor-binding protein-3 levels in premenopausal Japanese women. |
| PubMed:[Effects of soy extract on energy balance in ovariectomized rats]. |
| PubMed:Metabolism of isoflavones and lignans by the gut microflora: a study in germ-free and human flora associated rats. |
| PubMed:Soy product intake is inversely associated with serum homocysteine level in premenopausal Japanese women. |
| PubMed:Validation of a soy food-frequency questionnaire and evaluation of correlates of plasma isoflavone concentrations in postmenopausal women. |
| PubMed:Validation of a soy food frequency questionnaire with plasma concentrations of isoflavones in US adults. |
| PubMed:Solvent extraction selection in the determination of isoflavones in soy foods. |
| PubMed:Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice. |
| PubMed:Hormonal effects of soy in premenopausal women and men. |
| PubMed:Identification and concentration of soy isoflavones in commercial cat foods. |
| PubMed:Dietary soy isoflavone intake in older Japanese American women. |
| PubMed:Transfer of soy isoflavone into the egg yolk of chickens. |
| PubMed:Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice. |
| PubMed:Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein. |
| PubMed:Oxidative metabolism of the soy isoflavones daidzein and genistein in humans in vitro and in vivo. |
| PubMed:New advances in the understanding of the role of steroids and steroid receptors in disease. |
| PubMed:Placental transfer of the soy isoflavone genistein following dietary and gavage administration to Sprague Dawley rats. |
| PubMed:Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21(waf/cip1), p27(kip1), and Cdc25C expression. |
| PubMed:Soy isoflavones improve plasma lipids in normocholesterolemic and mildly hypercholesterolemic postmenopausal women. |
| PubMed:Soy consumption alters endogenous estrogen metabolism in postmenopausal women. |
| PubMed:Isoflavone phytoestrogens consumed in soy decrease F(2)-isoprostane concentrations and increase resistance of low-density lipoprotein to oxidation in humans. |
| PubMed:Soy isoflavone conjugation differs in fed and food-deprived rats. |
| PubMed:Genistein inhibits growth of estrogen-independent human breast cancer cells in culture but not in athymic mice. |
| PubMed:Soy isoflavones improve plasma lipids in normocholesterolemic, premenopausal women. |
| PubMed:Quantification of soy isoflavones, genistein and daidzein, and conjugates in rat blood using LC/ES-MS. |
| PubMed:Estrogenic activity of glycitein, a soy isoflavone. |
| PubMed:Effects of soy isoflavones on estrogen and phytoestrogen metabolism in premenopausal women. |
| PubMed:Soy isoflavone analysis: quality control and a new internal standard. |
| PubMed:Urinary equol excretion with a soy challenge: influence of habitual diet. |
| PubMed:HPLC-mass spectrometry analysis of isoflavones. |
| PubMed:Induction of micronucleus formation in mouse splenocytes by the soy isoflavone genistein in vitro but not in vivo. |
3D/inchi