EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

edetate calcium disodium
disodium((ethylenedinitrilo)tetraacetato)calciate(2-) hydrate

Supplier Sponsors

CAS Number: 23411-34-9Picture of molecule3D/inchi
Other(deleted CASRN):1317-32-4
FDA UNII: 5M645317UB
MDL:MFCD00149453
Molecular Weight:394.30185856
Formula:C10 H16 Ca N2 Na2 O9
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:chelating agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
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PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 363 Calcium disodium ethylenediaminetetraacetic acid (EDTA) and disodium EDTA View - notice PDF
 
Physical Properties:
Appearance:white powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 614.20 °C. @ 760.00 mm Hg (est)
Flash Point: 617.00 °F. TCC ( 325.20 °C. ) (est)
logP (o/w): -0.434 (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
American International Chemical, LLC.
CALCIUM DISODIUM EDTA
Santa Cruz Biotechnology
For experimental / research use only.
Ethylenediaminetetraacetic acid calcium disodium salt hydrate
Sigma-Aldrich
For experimental / research use only.
Ethylenediaminetetraacetic acid calcium disodium salt hydrate 97.0% (calc. based on dry substance, KT)
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
chelating agents
Recommendation for edetate calcium disodium usage levels up to:
 not for fragrance use.
 
Recommendation for edetate calcium disodium flavor usage levels up to:
 not for flavor use.
 
Safety References:
ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6335628
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
calcium;disodium;2-[2-[bis(carboxylatomethyl)azaniumyl]ethyl-(carboxylatomethyl)azaniumyl]acetate;hydrate
Chemidplus:0023411349
RTECS:EV7700000 for cas# 23411-34-9
 
References:
 calcium;disodium;2-[2-[bis(carboxylatomethyl)azaniumyl]ethyl-(carboxylatomethyl)azaniumyl]acetate;hydrate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):6335628
Pubchem (sid):135066051
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
ChemSpider:View
Formulations/Preparations:
•calcium disodium versenate injection, 5 ml ampul containing 200 mg of edetate calcium disodium per ml (1 g per ampul), in boxes containing 6 ampuls. •the food- and pharmaceutical-grade chemical is a mixture of the dihydrate and trihydrate of calcium disodium edta (predominantly the dihydrate), and contains not less than 97.0% and not more than 100.2% of c10h12can2na2o8, calculated on the anhydrous basis. •grades: usp, fcc
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 calcium disodium EDTA
 calcium disodium versenate
 calcium;disodium;2-[2-[bis(carboxylatomethyl)azaniumyl]ethyl-(carboxylatomethyl)azaniumyl]acetate;hydrate
 disodium ((ethylenedinitrilo)tetraacetato)calciate(2-) hydrate
 disodium((ethylenedinitrilo)tetraacetato)calciate(2-) hydrate
 versene CA
 

Articles:

PubMed:Mercury vapor inhalation and poisoning of a family.
PubMed:Edetate calcium disodium nanoparticle dry powder inhalation: a novel approach against heavy metal decorporation.
PubMed:A comparison of sodium calcium edetate (edetate calcium disodium) and succimer (DMSA) in the treatment of inorganic lead poisoning.
PubMed:[Cutaneous EBV-associated lymphoproliferative disorder in a dermatomyositis treated with immunosuppressive agents].
PubMed:Pediatric fatality secondary to EDTA chelation.
PubMed:Lead toxicity and chelation therapy.
PubMed:Low-level environmental exposure to lead and progressive chronic kidney diseases.
PubMed:Comparative in vitro efficacies of various catheter lock solutions.
PubMed:Oral treatment of avian lead intoxication with meso-2,3-dimercaptosuccinic acid.
PubMed:Lead poisoning and chelation in a mother-neonate pair.
PubMed:Lightening the lead load in children.
PubMed:A phase II study of [90Y] yttrium-capromab pendetide in the treatment of men with prostate cancer recurrence following radical prostatectomy.
PubMed:Effect of edetate calcium disodium on yttrium-90 activity in bone of mice.
PubMed:Localization of indium-111 in human malignant tumor xenografts and control by chelators.
PubMed:Mobilization of lead from bone in end-stage renal failure patients with secondary hyperparathyroidism.
PubMed:Lead mobilization test in children with lead poisoning: validation of a 5-hour edetate calcium disodium provocation test.
PubMed:Declining blood lead levels and cognitive changes in moderately lead-poisoned children.
PubMed:Chelation therapy to treat lead toxicity in children.
PubMed:Ten cases of acute lead intoxication among bridge workers in Louisiana.
PubMed:[Chronic nephropathy in saturnism. Comparative elimination of lead by classic chelating agents and peritoneal dialysis].
PubMed:Treatment of lead intoxication. Combined use of peritoneal dialysis and edetate calcium disodium.
 
Notes:
None found
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