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cefazolin sodium
sodium (6R,7R)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

Supplier Sponsors

CAS Number: 27164-46-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:248-278-4
FDA UNII: P380M0454Z
Beilstein Number:3585038
MDL:MFCD00056883
Molecular Weight:476.49517928
Formula:C14 H13 N8 Na O4 S3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:white powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): 1.133 (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Cefazolin sodium >97.0%(LC)(T)
Odor: characteristic
Use: Cefazolin sodium, derived from 7-amino-cephalosporanic acid, is a semi-synthetic, first-generation cephalosporin antibiotic. Semi-synthetic antibiotic derived from 7-amino-cepphalosporanic acid. An antibacterial.
Carbosynth
For experimental / research use only.
Cefazolin sodium salt
Glentham Life Sciences
Cefazolin sodium salt
Nectar Lifesciences
Cefazolin Sodium
Santa Cruz Biotechnology
For experimental / research use only.
Cefazolin sodium salt
Sigma-Aldrich: Sigma
For experimental / research use only.
Cefazolin sodium salt 89.1-110.1%
TCI AMERICA
For experimental / research use only.
Cefazolin Sodium Salt >98.0%(HPLC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-dog LD50 2200 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979.

intramuscular-human TDLo 14 mg/kg/D
SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE" GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Japan Medical Gazette. Vol. 8(8), Pg. 10, 1971.

intraperitoneal-mouse LD50 6200 mg/kg
Drugs in Japan Vol. 6, Pg. 404, 1982.

intravenous-mouse LD50 3900 mg/kg
Journal of Infectious Diseases. Vol. 128, Pg. S379, 1973.

oral-mouse LD50 > 11000 mg/kg
Chemotherapy Vol. 18, Pg. 528, 1970.

intravenous-rabbit LD50 2500 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979.

intraperitoneal-rat LD50 7400 mg/kg
Drugs in Japan Vol. 6, Pg. 404, 1982.

intravenous-rat LD50 2760 mg/kg
BEHAVIORAL: ATAXIA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Chemotherapy Vol. 35(Suppl

oral-rat LD50 > 11000 mg/kg
Chemotherapy Vol. 18, Pg. 528, 1970.

Dermal Toxicity:
subcutaneous-dog LD50 4000 mg/kg
GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Chemotherapy Vol. 18, Pg. 528, 1970.

subcutaneous-mouse LD50 7600 mg/kg
Journal of Infectious Diseases. Vol. 128, Pg. S379, 1973.

subcutaneous-rabbit LD50 > 6000 mg/kg
Chemotherapy Vol. 18, Pg. 528, 1970.

subcutaneous-rat LD50 10000 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Japan Medical Gazette. Vol. 8(8), Pg. 10, 1971.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for cefazolin sodium usage levels up to:
 not for fragrance use.
 
Recommendation for cefazolin sodium flavor usage levels up to:
 not for flavor use.
 
Safety References:
ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23675322
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
sodium;(6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Chemidplus:0027164461
RTECS:XI0390000 for cas# 27164-46-1
 
References:
 sodium;(6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):23675322
Pubchem (sid):134996986
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C08098
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2934.99.4400
MedlinePlusSupp:View
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 acef
 ancef
 atirin
 biazolina
 cefamedin
 cefamezin
 cefazil
 cefazina
 cefazolin sodium salt
 cefazoline sodium
 cephazolin sodium
 CEZ sodium
 elzogram
 firmacef
 gramaxin
 kefzol
 lampocef
 liviclina
 sodium (6R,7R)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate
 sodium (6R,7R)-3-(((5-Methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
 sodium (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
 sodium cefazolin
monosodium cefazolin
 sodium CEZ
 sodium;(6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
 totacef
 zolicef
 

Articles:

PubMed:Necrotizing Esophagitis and Bleeding Associated With Cefazolin.
PubMed:An unpredicted side effect of prophylactic antibiotic use.
PubMed:Isolation and characterisation of degradation impurities in the cefazolin sodium drug substance.
PubMed:Microarc oxidized TiO2 based ceramic coatings combined with cefazolin sodium/chitosan composited drug film on porous titanium for biomedical applications.
PubMed:On-line solid phase extraction using organic-inorganic hybrid monolithic columns for the determination of trace β-lactam antibiotics in milk and water samples.
PubMed:Timing of surgical antibiotic prophylaxis and the risk of surgical site infection.
PubMed:Evaluation of moxifloxacin 0.5% in treatment of nonperforated bacterial corneal ulcers: a randomized controlled trial.
PubMed:Postoperative antibacterial prophylaxis for the prevention of infectious complications associated with tube thoracostomy in patients undergoing elective general thoracic surgery: a double-blind, placebo-controlled, randomized trial.
PubMed:[Three cases of latex allergy complicated with anaphylaxis during cesarean section].
PubMed:The efficacy of prophylactic antibiotics administration prior to insertion of tunneled catheter in hemodialysis patients.
PubMed:Development of a novel chemiluminescence method for the determination of cefazolin sodium in injectable powder and human urine based on a luminol-Cu(III) complex reaction in alkaline medium.
PubMed:Stability of cefazolin sodium in polypropylene syringes and polyvinylchloride minibags.
PubMed:Cefazolin-sodium has no adverse effect on fracture healing in an experimental rabbit model.
PubMed:Investigation of the toxic functional group of cephalosporins by zebrafish embryo toxicity test.
PubMed:Sensitive chemiluminescence determination of thirteen cephalosporin antibiotics with luminol-copper(II) reaction.
PubMed:Stability of fortified cefazolin ophthalmic solutions prepared in artificial tears containing surfactant-based versus oxidant-based preservatives.
PubMed:Effect of intraarticular propolis in an experimental septic arthritis model.
PubMed:[Antibiotic susceptibility of pathogenic bacteria isolated from 893 children with lower respiratory infection in Guiyang].
PubMed:Kinetic spectrophotometric determination of certain cephalosporins using oxidized quercetin reagent.
PubMed:[Retropharyngeal abscesses: a retrospective analysis of 10 patients].
PubMed:The effects of methylprednisolone and cefazolin sodium on antioxidant status in experimentally induced maxillary sinusitis.
PubMed:Trends in antibacterial use in US academic health centers: 2002 to 2006.
PubMed:Potassium permanganate-glyoxal chemiluminescence system for flow injection analysis of cephalosporin antibiotics: cefalexin, cefadroxil, and cefazolin sodium in pharmaceutical preparations.
PubMed:Radiosensitivity study of cefazolin sodium.
PubMed:[Physical and chemical characteristics of a new cefazolin sodium hydrate crystal].
PubMed:Treatment of sinusitis with corticosteroids in combination with antibiotics in experimentally induced rhinosinusitis.
PubMed:Cefazolin-induced hypoprothrombinemia.
PubMed:Palonosetron Hydrochloride Compatiblity and Stability with Three B-Lactam Anitbiotic During Simulated Y-Site Adminstration.
PubMed:Pro-convulsant effect of cefazolin sodium against pentylenetetrazol- or picrotoxin-induced convulsions in mice.
PubMed:Preclinical testing of the Levitronix Ultramag pediatric cardiac assist device in a lamb model.
PubMed:[Simultaneous spectrophotometric determination of certain beta-lactam antibiotics in rabbit serum using multivariate calibration methods].
PubMed:Stability of cefazolin sodium in four heparinized and non-heparinized dialysate solutions at 38 degrees C.
PubMed:Infective endocarditis with an aortic periannular abscess extending along the right coronary artery.
PubMed:Infection management in a patient with a left ventricular assist device: a case report of long-term cefazolin sodium hydrate administration.
PubMed:Chemiluminescence flow-injection analysis of beta-lactam antibiotics using the luminol-permanganate reaction.
PubMed:Novel purification strategy for human PON1 and inhibition of the activity by cephalosporin and aminoglikozide derived antibiotics.
PubMed:In vitro activity of cefazoline and cefuroxime in presence of essential and trace elements.
PubMed:Clinical evaluation of ophthalmic lomefloxacin 0.3% in comparison with fortified cefazolin and gentamicin ophthalmic solutions in the treatment of presumed bacterial keratitis.
PubMed:[Sensitivity of nanoparticlized cefazolin sodium to the bacteria in vitro].
PubMed:Voltammetric behavior and assay of the antibiotic drug cefazolin sodium in bulk form and pharmaceutical formulation at a mercury electrode.
PubMed:Antibiotic activity and synergistic effect of antimicrobial peptide against pathogens from a patient with gallstones.
PubMed:In situ investigation of drug diffusion in hydrogels by the refractive index method.
PubMed:The release of cefazolin and gentamicin from biodegradable PLA/PGA beads.
PubMed:Fluorimetric determination of some antibiotics in raw material and dosage forms through ternary complex formation with terbium (Tb(3+)).
PubMed:The effects of some antibiotics on sheep lens glucose 6-phosphate dehydrogenase in vitro.
PubMed:The effect of additives on the crystallization of cefazolin sodium during freeze-drying.
PubMed:Chemical Stability of Cefazolin Sodium after Reconstituting in 0.9% Sodium Chloride Injection and Storage in Polypropylene Syringes for Pediatric Use.
PubMed:Stability of cefazolin sodium in icodextrin-containing peritoneal dialysis solution.
PubMed:Differences in neutrophil death among beta-lactam antibiotics after in vitro killing of bacteria.
PubMed:Effect of water content on the solid-state stability in two isomorphic clathrates of cephalosporin: cefazolin sodium pentahydrate (alpha form) and FK041 hydrate.
PubMed:Stability of three cephalosporin antibiotics in AutoDose Infusion System bags.
PubMed:A randomized prospective study of oral versus intravenous antibiotic prophylaxis against postoperative infection after sagittal split ramus osteotomy of the mandible.
PubMed:Compatibility and stability of linezolid injection admixed with three cephalosporin antibiotics.
PubMed:Comparison of topical 0.3% ofloxacin to fortified tobramycin-cefazolin in the therapy of bacterial keratitis.
PubMed:Pharmacokinetics of once daily intraperitoneal cefazolin in continuous ambulatory peritoneal dialysis patients.
PubMed:Structural relationship and desolvation behavior of cromolyn, cefazolin and fenoprofen sodium hydrates.
PubMed:Comparison of topical 0.3% ofloxacin with fortified tobramycin plus cefazolin in the treatment of bacterial keratitis.
PubMed:Stability of Ranitidine Hydrochloride with Cefazolin Sodium, Cefbuperazone Sodium, Cefoxitin Sodium and Cephalothin Sodium during Simulated Y-Site Administration.
PubMed:Comparative study of antibacterial activity of cefazolin sodium and of its crystalline modifications.
PubMed:Stability of cefazolin sodium eye drops.
PubMed:Combined therapies for composite graft infection after Bentall's procedure.
PubMed:Biodegradable polyanhydride devices of cefazolin sodium, bupivacaine, and taxol for local drug delivery: preparation, and kinetics and mechanism of in vitro release.
PubMed:Determinants of surgical site infection after breast surgery.
PubMed:Use of antibiotic-impregnated polymethyl methacrylate in horses with open or infected fractures or joints: 19 cases (1987-1995).
PubMed:Stability of cefazolin sodium and meperidine hydrochloride.
PubMed:Long-term stability of cefuroxime and cefazolin sodium in intravenous infusions.
PubMed:Comparative treatment of experimental Staphylococcus aureus endophthalmitis.
PubMed:Isolation of Campylobacter spp. from slaughtered cattle and swine on blood-free selective medium.
PubMed:Efficacy of ofloxacin vs cefazolin and tobramycin in the therapy for bacterial keratitis. Report from the Bacterial Keratitis Study Research Group.
PubMed:Stability of cefazolin sodium-famotidine admixture.
PubMed:[Brain abscess ruptured into the lateral ventricle: the usefulness of treatment by intraventricular irrigation with antibiotics. A case report].
PubMed:[Cefazolin sodium].
PubMed:Visual, turbidimetric, and particle-content assessment of compatibility of vinorelbine tartrate with selected drugs during simulated Y-site injection.
PubMed:Compatibility of ondansetron hydrochloride with fluconazole, ceftazidime, aztreonam, and cefazolin sodium under simulated Y-site conditions.
PubMed:Treatment of bleb infection after glaucoma surgery.
PubMed:Preoperative skin preparation and intraoperative pelvic irrigation: impact on post-cesarean endometritis and wound infection.
PubMed:Stability of cefazolin sodium and metronidazole at 8 degrees C for use as an i.v. admixture.
PubMed:Evaluation of biodegradable cefazolin sodium microspheres for the prevention of infection in rabbits with experimental open tibial fractures stabilized with internal fixation.
PubMed:An in vitro model for assessing muscle irritation of antibiotics using rat primary cultured skeletal muscle fibers.
PubMed:Bioavailability and bioequivalence of veterinary drug dosage forms, with particular reference to horses: an overview.
PubMed:Prophylactic antibiotics for head and neck surgery with flap reconstruction.
PubMed:Musculoskeletal and soft tissue Aeromonas infection: an environmental disease.
PubMed:Kinetics of a phase transition in a frozen solution.
PubMed:[Stability of cefazolin sodium as eyedrops in various solutions].
PubMed:An in vitro study of the potency and stability of fortified ophthalmic antibiotic preparations.
PubMed:Antimicrobial prophylaxis in coronary bypass surgery: a critical appraisal.
PubMed:Stability of cefazolin sodium in peritoneal dialysis solutions.
PubMed:[Nephrotoxicity of cefpirome sulfate in rabbits--single and multiple intravenous administration].
PubMed:[Antigenicity study of cefpirome sulfate].
PubMed:Comparative treatment of experimental Staphylococcus epidermidis endophthalmitis.
PubMed:Vitreous cefazolin levels after intravenous injection. Effects of inflammation, repeated antibiotic doses, and surgery.
PubMed:Changes in the antibacterial activity of melanin-bound drugs.
PubMed:Effect of primary fluids and dilutional volumes on the delivery of cefazolin sodium by a membrane infusion device.
PubMed:Transscleral iontophoresis of dexamethasone.
PubMed:Stability of cefazolin sodium, cefoxitin sodium, ceftazidime, and penicillin G sodium in portable pump reservoirs.
PubMed:Effect of surgical blood loss and volume replacement on antibiotic pharmacokinetics.
PubMed:Posterior nasal packing. Are intravenous antibiotics really necessary?
PubMed:Effects of excipients on the crystallization of pharmaceutical compounds during lyophilization.
PubMed:Prophylactic antibiotherapy in abdominal surgery. First- vs third-generation cephalosporins.
PubMed:Influence of drugs on albumin and bilirubin interaction.
PubMed:Effect of cefazolin on the corneal endothelium. An experimental study.
PubMed:Prophylactic appendicectomy during elective cholecystectomy: effects on morbidity. A prospective controlled study.
PubMed:Nontoxic concentration of antibiotics for intravitreal use--evaluated by human in-vitro ERG.
PubMed:Compatibility and stability of cefazolin sodium, clindamycin phosphate, and gentamicin sulfate in two intravenous solutions.
PubMed:Reduction of incorrect antibiotic dosing through a structured educational order form.
PubMed:Antibiotic prophylaxis in open-heart surgery: a comparison of cefamandole, cefuroxime, and cefazolin.
PubMed:Estimation of the degree of crystallinity of cefazolin sodium by X-ray and infrared methods.
PubMed:Hygroscopicity of cefazolin sodium: application to evaluate the crystallinity of freeze-dried products.
PubMed:[Effects on ERG and VEP of intravitreal injection of cefazolin sodium].
PubMed:Automatic interchange and selective culture and sensitivity reporting of cefazolin sodium.
PubMed:[Effect of cefodizime sodium on the kidney function in male rabbits--single and 7-day repeated intravenous administration].
PubMed:Retinal toxicity of antibiotics: evaluation by electroretinogram.
PubMed:In vitro inactivation of aminoglycosides by cephalosporin antibiotics.
PubMed:Rate-controlled absorption enhancement of rectally administered cefazolin in rats by a glyceride mixture (MGK).
PubMed:Effect of solvent addition and thermal treatment on freeze drying of cefazolin sodium.
PubMed:Personnel time and preparation costs for compounded versus premixed intravenous admixtures in three community hospitals.
PubMed:Stability of cefazolin sodium in various artificial tear solutions and aqueous vehicles.
PubMed:Antibiotic prophylaxis for facial fractures. A prospective, randomized clinical trial.
PubMed:Inaccurate acquisition costs for hospital-reconstituted cefazolin sodium injection.
PubMed:Intravitreal vancomycin. Retinal toxicity, clearance, and interaction with gentamicin.
PubMed:Effects of antibiotics on the in vitro ERG of the albino rabbit. Penicillins and cephalosporins antibiotics.
PubMed:Infusion phlebitis associated with a programmable syringe-pump system versus gravity-feed minibottles.
PubMed:Cost analysis of using premixed frozen versus hospital-reconstituted cefazolin sodium injection.
PubMed:The Limulus amebocyte lysate assay. A rapid and sensitive method for diagnosing early gram-negative peritonitis in patients undergoing continuous ambulatory peritoneal dialysis.
PubMed:Preparing and administering cefazolin sodium small-volume injections.
PubMed:Interference by cephalosporins with creatinine measurement by desk-top analyzers.
PubMed:Vibrio cholerae non-01 cellulitis.
PubMed:Comparison of seven methods of preparing and administering cefazolin sodium small-volume injections.
PubMed:[Surgical approach to abdominal aortic aneurysm with malignant alimentary tract tumor: report of three cases].
PubMed:Crystal formation after reconstituting cefazolin sodium with 0.9% sodium chloride injection.
PubMed:In vitro inactivation of tobramycin by cephalosporins.
PubMed:Short-term prophylactic antibiotic for elective abdominal hysterectomy: how short?
PubMed:Stability of clindamycin phosphate and ceftizoxime sodium, cefoxitin sodium, cefamandole nafate, or cefazolin sodium in two intravenous solutions.
PubMed:Colostomy wound closure.
PubMed:Intraoperative serum and tissue activity of cefazolin and cefoxitin.
PubMed:Crystal formation after reconstituting cefazolin sodium with 0.9% sodium chloride injection.
PubMed:Peritonitis in children undergoing continuous ambulatory peritoneal dialysis.
PubMed:Nonaqueous cephalosporin suspension for parenteral administration: cefazolin sodium.
PubMed:Cefazolin sodium in prophylaxis.
PubMed:Listeria monocytogenes pericarditis in a chronically hemodialyzed patient.
PubMed:Concentrations of cefazolin sodium in ischemic extremities.
PubMed:Comparison of six methods for preparing cefazolin sodium for intermittent injection.
PubMed:Effect of topical antibiotic solutions on corneal epithelial wound healing.
PubMed:Benefit-cost analysis of antimicrobial prophylaxis in abdominal and vaginal hysterectomy.
PubMed:Coagulase-negative staphylococcal bacteremia in patients receiving immunosuppressive therapy.
PubMed:Influencing drug use through prescribing restrictions.
PubMed:Rifampin and cefazolin as prophylactic agents. A comparison in an animal model of vascular graft infection.
PubMed:Effect of vitamin B complex and ascorbic acid on the antimicrobial activity of cefazolin sodium.
PubMed:Toxicity, efficacy, and clearance of intravitreally injected of cefazolin.
PubMed:Tolerant Staphylococcus aureus causing vertebral osteomyelitis.
PubMed:A prospective randomized study of prophylactic mannitol (10%)-neomycin-cefotaxime therapy in patients undergoing elective colonic and rectal surgery.
PubMed:Cimetidine hydrochloride compatibility. III: Room temperature stability in drug admixtures.
PubMed:Cost containment through restriction of cephalosporins.
PubMed:Effect of multidose therapy on cerebrospinal fluid penetration of cefazolin.
PubMed:Airborne drug levels in a laminar-flow hood.
PubMed:Quantitation of carbenicillin disodium, cefazolin sodium, cephalothin sodium, nafcillin sodium, and ticarcillin disodium by high-pressure liquid chromatography.
PubMed:Antibiotic activity in surgical incisions. The basis of prophylaxis in selected operations.
PubMed:Wound infections after transplant nephrectomy.
PubMed:Activity of antibiotic admixtures subjected to different freeze-thaw treatments.
PubMed:Seizures associated with high cerebrospinal fluid concentrations of cefazolin.
PubMed:Stability of cefazolin sodium admixtures in plastic bags after thawing by microwave radiation.
PubMed:Cefazolin vs penicillin. Treatment of uncomplicated pneumococcal pneumonia.
PubMed:One-dose antibiotic prophylaxis against wound infection after appendicectomy: a randomized trial of clindamycin, cefazolin sodium and a placebo.
PubMed:Empiric therapy of febrile granulocytopenic patients.
PubMed:Cefazolin treatment of bacterial infections. In vitro and in vivo evaluation.
PubMed:[Antipyretic activity of SL-573 (II) (author's transl)].
PubMed:Cephalosporins: use review and cost analysis.
PubMed:Efficacy of penicillin G, cefazolin, and gentamicin in M-K medium at 4 degrees C.
PubMed:Quantitative crystallinity determinations for beta-lactam antibiotics by solution calorimetry: correlations with stability.
PubMed:Infective endocarditis caused by Streptococcus bovis resistant to the lethal effect of penicillin G.
PubMed:Treatment of necrotizing fasciitis caused by Staphylococcus epidermidis.
PubMed:Pharmacy and therapeutics committee review of the parenteral cephalosporins.
PubMed:The simultaneous quantitative determination of cephalothin and cefazolin in serum by high pressure liquid chromatography.
PubMed:The influence of biliary disease on the excretion of cefazolin in human bile.
PubMed:Unsuccessful treatment of staphylococcal endocarditis with cefazolin.
PubMed:Stability of frozen solutions of cefazolin sodium.
PubMed:Kefzol (cefazolin sodium, Lilly).
PubMed:Intraocular penetration of cefazolin sodium in rabbits.
PubMed:Stability of parenteral solutions of cefazolin sodium.
PubMed:Cefazolin sodium.
PubMed:Evaluation of cefazolin, a new cephalosporin antibiotic.
PubMed:Clinical and in vitro evaluation of cefazolin, a new cephalosporin antibiotic.
 
Notes:
a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. it attains high serum levels and is excreted quickly via the urine.
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