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tricalcium silicate
calcium silicate (Ca3SiO5)

Supplier Sponsors

CAS Number: 12168-85-3Picture of molecule3D/inchi
Other(deleted CASRN):12285-92-6
ECHA EINECS - REACH Pre-Reg:235-336-9
FDA UNII: 404G39282C
Molecular Weight:228.31530000
Formula:Ca3 O5 Si
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:food additive
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Google Patents:Search
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Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
182.2906 Tricalcium silicate View - review
 
Physical Properties:
Appearance:colorless crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): 0.651 (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Tricalcium silicon pentaoxide
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
food additive
Recommendation for tricalcium silicate usage levels up to:
 not for fragrance use.
 
Recommendation for tricalcium silicate flavor usage levels up to:
 not for flavor use.
 
Safety References:
ClinicalTrials.gov:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):12168-85-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :25523
National Institute of Allergy and Infectious Diseases:Data
dicalcium oxocalcium silicate
Chemidplus:0012168853
 
References:
 dicalcium oxocalcium silicate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:12168-85-3
Pubchem (cid):25523
Pubchem (sid):134990531
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
FooDB:FDB013561
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
hydraulic cement in the form of finely divided, gray powder composed of lime, alumina, silica and iron oxide as tetracalcium aluminoferate, tricalcium aluminate, tricalcium silicate, and dicalcium silicate small amounts of magnesia, sodium, potassium, and sulfur are also present. cement, portland
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 calcium oxide silicate (Ca3O(SiO4))
 calcium silicate (Ca3SiO5)
 calcium silicon oxide (Ca3SiO5)
 dicalcium oxocalcium silicate
 

Articles:

PubMed:Primate pulpal healing after exposure and TheraCal application.
PubMed:Radiopacifier Particle Size Impacts the Physical Properties of Tricalcium Silicate-based Cements.
PubMed:Interfacial characteristics of Biodentine and MTA with dentine in simulated body fluid.
PubMed:Comparison of Quick-Set and Mineral Trioxide Aggregate Root-end Fillings for the Regeneration of Apical Tissues in Dogs.
PubMed:Influence of composition on setting kinetics of new injectable and/or fast setting tricalcium silicate cements.
PubMed:In situ assessment of the setting of tricalcium silicate-based sealers using a dentin pressure model.
PubMed:Tricalcium silicate cements with resins and alternative radiopacifiers.
PubMed:Ion release, porosity, solubility, and bioactivity of MTA Plus tricalcium silicate.
PubMed:Comparative evaluation of shear bond strength and microleakage of tricalcium silicate-based restorative material and radioopaque posterior glass ionomer restorative cement in primary and permanent teeth: an in vitro study.
PubMed:Mineral trioxide aggregate (MTA)-like materials: an update review.
PubMed:Investigation of a novel mechanically mixed mineral trioxide aggregate (MM-MTA(™) ).
PubMed:Hydration of Biodentine, Theracal LC, and a prototype tricalcium silicate-based dentin replacement material after pulp capping in entire tooth cultures.
PubMed:Capping a pulpotomy with calcium aluminosilicate cement: comparison to mineral trioxide aggregates.
PubMed:Comparison of pulpal responses to pulpotomy and pulp capping with biodentine and mineral trioxide aggregate in dogs.
PubMed:Evaluation of shear bond strength of two resin-based composites and glass ionomer cement to pure tricalcium silicate-based cement (Biodentine®).
PubMed:Zinc incorporation improves biological activity of beta-tricalcium silicate resin-based cement.
PubMed:Sealers and warm gutta-percha obturation techniques.
PubMed:Characterization of un-hydrated and hydrated BioAggregate™ and MTA Angelus™
PubMed:Zoledronate and ion-releasing resins impair dentin collagen degradation.
PubMed:X-ray diffraction analysis of MTA-Plus, MTA-Angelus and DiaRoot BioAggregate.
PubMed:Cytocompatibility and antibacterial properties of capping materials.
PubMed:Biodentine induces human dental pulp stem cell differentiation through mitogen-activated protein kinase and calcium-/calmodulin-dependent protein kinase II pathways.
PubMed:Frequently asked questions in direct pulp capping of permanent teeth.
PubMed:Effect of saliva and blood contamination on the bi-axial flexural strength and setting time of two calcium-silicate based cements: Portland cement and biodentine.
PubMed:Influence of QMix irrigant on the micropush-out bond strength of biodentine and white mineral trioxide aggregate.
PubMed:Acidic pH weakens the microhardness and microstructure of three tricalcium silicate materials.
PubMed:A force field for tricalcium aluminate to characterize surface properties, initial hydration, and organically modified interfaces in atomic resolution.
PubMed:Hydration characteristics of Biodentine and Theracal used as pulp capping materials.
PubMed:Cytotoxicity and physical properties of tricalcium silicate-based endodontic materials.
PubMed:Effects of tricalcium silicate cements on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells in vitro.
PubMed:Investigation of chemical changes in sealers during application of the warm vertical compaction technique.
PubMed:New treatment option for an incomplete vertical root fracture--a preliminary case report.
PubMed:Biodentine™ material characteristics and clinical applications: a review of the literature.
PubMed:Application of hydration reaction on the removal of recalcitrant contaminants in leachate after biological treatment.
PubMed:In vitro biocompatibility of a dentine substitute cement on human MG63 osteoblasts cells: Biodentine™ versus MTA(®).
PubMed:Effect of Biodentine™ on the proliferation, migration and adhesion of human dental pulp stem cells.
PubMed:Conservative approach of a symptomatic carious immature permanent tooth using a tricalcium silicate cement (Biodentine): a case report.
PubMed:Comparison of the radiopacities of different root-end filling and repair materials.
PubMed:Shear bond strengths of different adhesive systems to biodentine.
PubMed:Trace metal contents of three tricalcium silicate materials: MTA Angelus, Micro Mega MTA and Bioaggregate.
PubMed:Porosity and root dentine to material interface assessment of calcium silicate-based root-end filling materials.
PubMed:Physical properties of 5 root canal sealers.
PubMed:[Comparative study of antimicrobial activity of "Biodentin" and "Rootdent" cements and "Futurabond NR" adhesive].
PubMed:In vitro osteogenic/dentinogenic potential of an experimental calcium aluminosilicate cement.
PubMed:Role of the extracellular signal-regulated kinase 1/2 pathway in driving tricalcium silicate-induced proliferation and biomineralization of human dental pulp cells in vitro.
PubMed:In vitro cytotoxicity of white MTA, MTA Fillapex® and Portland cement on human periodontal ligament fibroblasts.
PubMed:Investigation of Biodentine as dentine replacement material.
PubMed:Response of human dental pulp capped with biodentine and mineral trioxide aggregate.
PubMed:Biointeractivity-related versus chemi/physisorption-related apatite precursor-forming ability of current root end filling materials.
PubMed:Investigation of the hydration and bioactivity of radiopacified tricalcium silicate cement, Biodentine and MTA Angelus.
PubMed:Influence of light and oxygen on the color stability of five calcium silicate-based materials.
PubMed:In vitro cytotoxicity evaluation of a novel root repair material.
PubMed:New options for restoring a deep carious lesion.
PubMed:Spheroid model study comparing the biocompatibility of Biodentine and MTA.
PubMed:Pulp capping materials-is there anything better than Dycal?
PubMed:Chemical characteristics of mineral trioxide aggregate and its hydration reaction.
PubMed:Effect of various endodontic irrigants on the push-out bond strength of biodentine and conventional root perforation repair materials.
PubMed:Influence of acrylic superplasticizer and cellulose-ether on the kinetics of tricalcium silicate hydration reaction.
PubMed:Variation of the ultrasonic response of a dental implant embedded in tricalcium silicate-based cement under cyclic loading.
PubMed:A biocompatible and bioactive replacement for dentine: is this a reality? The properties and uses of a novel calcium-based cement.
PubMed:Clinical case reports using a novel calcium-based cement.
PubMed:Characterization of set Intermediate Restorative Material, Biodentine, Bioaggregate and a prototype calcium silicate cement for use as root-end filling materials.
PubMed:Biodentine used as a pulp-capping agent in primary pig teeth.
PubMed:Mineral trioxide aggregate with anti-washout gel - properties and microstructure.
PubMed:Investigation of the physical properties of tricalcium silicate cement-based root-end filling materials.
PubMed:Vital pulp therapy with pulp capping.
PubMed:New nanostructural biomaterials based on active silicate systems and hydroxyapatite: characterization and genotoxicity in human peripheral blood lymphocytes.
PubMed:In vitro studies of calcium phosphate silicate bone cements.
PubMed:Effect of tricalcium silicate (Ca(3)SiO(5)) bioactive material on reducing enamel demineralization: an in vitro pH-cycling study.
PubMed:Effect of a calcium-silicate-based restorative cement on pulp repair.
PubMed:Biodentine induces immortalized murine pulp cell differentiation into odontoblast-like cells and stimulates biomineralization.
PubMed:A study on the sealing ability and antibacterial activity of Ca3SiO5/CaCl2 composite cement for dental applications.
PubMed:Reactions and surface interactions of saccharides in cement slurries.
PubMed:Proactive intervention dentistry: a model for oral care through life.
PubMed:In vitro microleakage of Biodentine as a dentin substitute compared to Fuji II LC in cervical lining restorations.
PubMed:Effects of calcium silicate-based materials on collagen matrix integrity of mineralized dentin.
PubMed:Antibacterial activity of a new mineral trioxide aggregate-based root canal sealer.
PubMed:Clinical evaluation of the performance and safety of a new dentine substitute, Biodentine, in the restoration of posterior teeth - a prospective study.
PubMed:The microstructure and surface morphology of radiopaque tricalcium silicate cement exposed to different curing conditions.
PubMed:Characterization and analyses of acid-extractable and leached trace elements in dental cements.
PubMed:Biodentine(TM) induces TGF-β1 release from human pulp cells and early dental pulp mineralization.
PubMed:The effect of curing conditions on the physical properties of tricalcium silicate cement for use as a dental biomaterial.
PubMed:Bioactive composite bone cement based on α-tricalcium phosphate/tricalcium silicate.
PubMed:Hydration kinetics of tricalcium silicate by calorimetric methods.
PubMed:Antibacterial activity of two MTA-based root canal sealers.
PubMed:Effect of tricalcium silicate on the proliferation and odontogenic differentiation of human dental pulp cells.
PubMed:Biomimetic calcium-silicate cements support differentiation of human orofacial mesenchymal stem cells.
PubMed:Tricalcium silicate induced mineralization for occlusion of dentinal tubules.
PubMed:Characterization and hydration kinetics of tricalcium silicate cement for use as a dental biomaterial.
PubMed:Anti-washout carboxymethyl chitosan modified tricalcium silicate bone cement: preparation, mechanical properties and in vitro bioactivity.
PubMed:Nanostructure of calcium silicate hydrates in cements.
PubMed:Effect of tricalcium aluminate on the properties of tricalcium silicate-tricalcium aluminate mixtures: setting time, mechanical strength and biocompatibility.
PubMed:Biomimetic calcium-silicate cements aged in simulated body solutions. Osteoblast response and analyses of apatite coating.
PubMed:Apatite formation on bioactive calcium-silicate cements for dentistry affects surface topography and human marrow stromal cells proliferation.
PubMed:The apatite formation ability of CaF2 doping tricalcium silicates in simulated body fluid.
PubMed:Phase composition of ProRoot mineral trioxide aggregate by X-ray powder diffraction.
PubMed:[Study of spectra characteristics of Ca3SiO5 : Eu2+ phosphor].
PubMed:Sealing ability of grar MTA AngelusTM, CPM TM and MBPc used as apical plugs.
PubMed:Novel bioactive composite bone cements based on the beta-tricalcium phosphate-monocalcium phosphate monohydrate composite cement system.
PubMed:Characterization and chemical activity of Portland cement and two experimental cements with potential for use in dentistry.
PubMed:Effect of sodium carbonate solution on self-setting properties of tricalcium silicate bone cement.
PubMed:Adsorption of polyelectrolytes and its influence on the rheology, zeta potential, and microstructure of various cement and hydrate phases.
PubMed:Induction of specific cell responses to a Ca(3)SiO(5)-based posterior restorative material.
PubMed:Immobilisation of heavy metal in cement-based solidification/stabilisation: a review.
PubMed:Study on physicochemical properties and in vitro bioactivity of tricalcium silicate-calcium carbonate composite bone cement.
PubMed:Characterization of carbonated tricalcium silicate and its sorption capacity for heavy metals: a micron-scale composite adsorbent of active silicate gel and calcite.
PubMed:Nano-pH sensor for the study of reactive materials.
PubMed:Self-setting properties and in vitro bioactivity of Ca3SiO5/CaSO4.1/2H2O composite cement.
PubMed:The constitution, physical properties and biocompatibility of modified accelerated cement.
PubMed:Self-setting properties and in vitro bioactivity of calcium sulfate hemihydrate-tricalcium silicate composite bone cements.
PubMed:Hydration mechanisms of mineral trioxide aggregate.
PubMed:Characterisation of products of tricalcium silicate hydration in the presence of heavy metals.
PubMed:Characterization of Ca3SiO5/CaCl2 composite cement for dental application.
PubMed:Novel tricalcium silicate/monocalcium phosphate monohydrate composite bone cement.
PubMed:In vitro bioactivity of novel tricalcium silicate ceramics.
PubMed:Near-infrared spectroscopy investigation of the water confined in tricalcium silicate pastes.
PubMed:Hydration process of cement in the presence of a cellulosic additive. A calorimetric investigation.
PubMed:Hydration of tricalcium and dicalcium silicate mixtures studied using quasielastic neutron scattering.
PubMed:Investigation into the stabilization/solidification performance of Portland cement through cement clinker phases.
PubMed:X-ray diffraction analysis of mineral trioxide aggregate and Portland cement.
PubMed:Formation of the C-S-H Layer during early hydration of tricalcium silicate grains with different sizes.
PubMed:Characterization of Portland cement for use as a dental restorative material.
PubMed:Controlling the cohesion of cement paste.
PubMed:The self-setting properties and in vitro bioactivity of tricalcium silicate.
PubMed:The influence of superplasticizers on the first steps of tricalcium silicate hydration studied by NMR techniques.
PubMed:The constitution of mineral trioxide aggregate.
PubMed:Preparation and characterization of novel tricalcium silicate bioceramics.
PubMed:Characterization and preliminary assessment of a sorbent produced by accelerated mineral carbonation.
PubMed:Adsorption and heterocoagulation of nonionic surfactants and latex particles on cement hydrates.
PubMed:Age-dependent dynamics of water in hydrated cement paste.
PubMed:Global hydration kinetics of tricalcium silicate cement.
PubMed:Calcium hydroxide: its role in the fracture of tricalcium silicate paste.
 
Notes:
Anticaking agent for table salt
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