EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

alpha-galactosidase
melibiase

Supplier Sponsors

CAS Number: 9025-35-8
Other(deleted CASRN):9013-52-9
ECHA EC Number:232-792-0
FDA UNII: Search
MDL:MFCD00130486
Category:enzyme preparations and microorganisms
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
American Laboratories
alpha-Galactosidase
Charkit Chemical
ALPHA GALACTOSIDASE 10000
Pangaea Sciences
Galactosidase
Shaanxi Y-Herb Biotechnology
Healthy Alpha Galactosidase Enzyme Powder Supplement Water Soluble
Sigma-Aldrich: Sigma
For experimental / research use only.
a-Galactosidase from green coffee beans ammonium sulfate suspension, ≥9 units/mg protein
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
enzyme preparations and microorganisms
Recommendation for alpha-galactosidase usage levels up to:
 not for fragrance use.
 
Recommendation for alpha-galactosidase flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Annual report on the preparatory work for the evaluation of food enzymes – Toxicological part
View page or View pdf

Safety and efficacy of FRA® Octazyme C Dry(endo-1,4-ß-xylanase, mannan-endo-1,4-ß-mannosidase, a-amylase, endo-1,3(4)-ß-glucanase, pectinase, endo-1,4-ß-glucanase, protease, a-galactosidase) as a feed additive for weaned piglets and chickens for fattening
View page or View pdf

ClinicalTrials.gov:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
Chemidplus:0009025358
 
References:
Pubchem (sid):135289799
 
Other Information:
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
MedlinePlusSupp:View
VCF-Online:VCF Volatile Compounds in Food
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 alpha-galactosidase
Search PMC Picture
 
Synonyms:
 alpha gal 500
 beano
 melibiase
 sumizyme AGS
 validase AGS
 

Articles:

PubMed:A New α-Galactosidase from Thermoacidophilic Alicyclobacillus sp. A4 with Wide Acceptor Specificity for Transglycosylation.
PubMed:Thermostability of Probiotics and Their α -Galactosidases and the Potential for Bean Products.
PubMed:Production of α- and β-galactosidases from Bifidobacterium longum subsp. longum RD47.
PubMed:A systems approach to designing next generation vaccines: combining α-galactose modified antigens with nanoparticle platforms.
PubMed:Digestive enzymes activity in subsequent generations of Cameraria ohridella larvae harvested from horse chestnut trees after treatment with imidacloprid.
PubMed:Red meat allergy in Sweden: association with tick sensitization and B-negative blood groups.
PubMed:Enzymatic hydrolysis preparation of mono-O-lauroylsucrose via a mono-O-lauroylraffinose intermediate.
PubMed:Cicer α-galactosidase immobilization onto functionalized graphene nanosheets using response surface method and its applications.
PubMed:Characterization of α-galacto-oligosaccharides formed via heterologous expression of α-galactosidases from Lactobacillus reuteri in Lactococcus lactis.
PubMed:Biotechnological potential of microbial α-galactosidases.
PubMed:[Therapy for systemic metabolic disorders based on the detection of basic corneal landmarks in childhood].
PubMed:Gastrointestinal morphology and function in turkeys fed diets diluted with whole grain wheat.
PubMed:Isolation and characterization of an agarase-producing bacterial strain, Alteromonas sp. GNUM-1, from the West Sea, Korea.
PubMed:Delayed anaphylactic reaction to mammalian meat.
PubMed:Streptococcus danieliae sp. nov., a novel bacterium isolated from the caecum of a mouse.
PubMed:Functional analysis of family GH36 α-galactosidases from Ruminococcus gnavus E1: insights into the metabolism of a plant oligosaccharide by a human gut symbiont.
PubMed:Cicer α-galactosidase immobilization onto chitosan and Amberlite MB-150: optimization, characterization, and its applications.
PubMed:Levansucrase and sucrose phoshorylase contribute to raffinose, stachyose, and verbascose metabolism by lactobacilli.
PubMed:Characterization of a β-glucosidase with transgalactosylation capacity from the zygomycete Rhizomucor miehei.
PubMed:Purification and characterization of α-galactosidase from white chickpea (Cicer arietinum).
PubMed:Imbibition of soybean seeds in warm water results in the release of copious amounts of Bowman-Birk protease inhibitor, a putative anticarcinogenic agent.
PubMed:Characterization of a protease-resistant α-galactosidase from the thermophilic fungus Rhizomucor miehei and its application in removal of raffinose family oligosaccharides.
PubMed:Survival of freeze-dried microcapsules of α-galactosidase producing probiotics in a soy bar matrix.
PubMed:α-Galactosidase/sucrose kinase (AgaSK), a novel bifunctional enzyme from the human microbiome coupling galactosidase and kinase activities.
PubMed:Purification and characterization of Aspergillus terreus α-galactosidases and their use for hydrolysis of soymilk oligosaccharides.
PubMed:Effects of dietary addition of Macleaya cordata alkaloid extract on growth performance, caecal indices and breast meat fatty acids profile in male broilers.
PubMed:An alpha-galactosidase from an acidophilic Bispora sp. MEY-1 strain acts synergistically with beta-mannanase.
PubMed:Effect of prebiotics on viability and growth characteristics of probiotics in soymilk.
PubMed:Crystallization and preliminary X-ray diffraction data of alpha-galactosidase from Saccharomyces cerevisiae.
PubMed:A food-grade industrial arming yeast expressing beta-1,3-1,4-glucanase with enhanced thermal stability.
PubMed:Molecular cloning and expression of a novel protease-resistant GH-36 alpha-galactosidase from Rhizopus sp. F78 ACCC 30795.
PubMed:Viability and growth characteristics of Lactobacillus in soymilk supplemented with B-vitamins.
PubMed:Characterisation of specific activities and hydrolytic properties of cell-wall-degrading enzymes produced by Trichoderma reesei Rut C30 on different carbon sources.
PubMed:Evaluation of agrowastes as immobilizers for probiotics in soy milk.
PubMed:Enhancement of alpha- and beta-galactosidase activity in Lactobacillus reuteri by different metal ions.
PubMed:A beta-l-Arabinopyranosidase from Streptomyces avermitilis is a novel member of glycoside hydrolase family 27.
PubMed:Molecular characterization of native isolates of lactic acid bacteria, bifidobacteria and yeasts for beneficial attributes.
PubMed:A novel protease-resistant alpha-galactosidase with high hydrolytic activity from Gibberella sp. F75: gene cloning, expression, and enzymatic characterization.
PubMed:Debaryomyces hansenii UFV-1 intracellular alpha-galactosidase characterization and comparative studies with the extracellular enzyme.
PubMed:Effect of enzyme supplementation and acidification of diets on nutrient digestibility and growth performance of broiler chicks.
PubMed:A novel alpha-galactosidase from Bifidobacterium bifidum with transgalactosylating properties: gene molecular cloning and heterologous expression.
PubMed:Enzyme activities of lactic acid bacteria from a pearl millet fermented gruel (ben-saalga) of functional interest in nutrition.
PubMed:Enzymatic removal of flatulence-inducing sugars in chickpea milk using free and polyvinyl alcohol immobilized alpha-galactosidase from Aspergillus oryzae.
PubMed:Optimization of growth of Lactobacillus acidophilus FTCC 0291 and evaluation of growth characteristics in soy whey medium: a response surface methodology approach.
PubMed:Reduction of soybean oligosaccharides and properties of alpha-D-galactosidase from Lactobacillus curvatus R08 and Leuconostoc mesenteroides [corrected] JK55.
PubMed:High-throughput identification and validation of in situ-expressed genes of Lactococcus lactis.
PubMed:Short-term efficacy of enzyme replacement therapy in Korean patients with Fabry disease.
PubMed:An overview of mannan structure and mannan-degrading enzyme systems.
PubMed:Ability of Lactobacillus fermentum to overcome host alpha-galactosidase deficiency, as evidenced by reduction of hydrogen excretion in rats consuming soya alpha-galacto-oligosaccharides.
PubMed:Optimization of the fermentation medium for alpha-galactosidase production from Aspergillus foetidus ZU-G1 using response surface methodology.
PubMed:[Construction of food-grade inducible expression system in Lactococcus lactis and expression of fusion OprF/H from Pseudomonas aeruginosa].
PubMed:Response surface methodology for optimizing the fermentation medium of alpha-galactosidase in solid-state fermentation.
PubMed:Effect of cultivating conditions on alpha-galactosidase production by a novel Aspergillus foetidus ZU-G1 strain in solid-state fermentation.
PubMed:Effect of a kestose and nystose preparation on growth performance and gastrointestinal tract function of turkeys.
PubMed:Alpha-galactosidase A in vascular disease.
PubMed:Processing of soybean products by semipurified plant and microbial alpha-galactosidases.
PubMed:[Effectiveness of enzyme preparations of fodder in the degradation of nonstarch polysaccharides from grain substrates].
PubMed:The effect of oral alpha-galactosidase on intestinal gas production and gas-related symptoms.
PubMed:A novel thermostable alpha-galactosidase from the thermophilic fungus Thermomyces lanuginosus CBS 395.62/b: purification and characterization.
PubMed:A food-grade expression/secretion vector for Lactococcus lactis that uses an alpha-galactosidase gene as a selection marker.
PubMed:Metabolism of quercetin and rutin by the pig caecal microflora prepared by freeze-preservation.
PubMed:Construction and evaluation of food-grade vectors for Lactococcus lactis using aspartate aminotransferase and alpha-galactosidase as selectable markers.
PubMed:Cecal parameters of rats fed diets containing grapefruit polyphenols and inulin as single supplements or in a combination.
PubMed:Biochemical composition and indigestible oligosaccharides in Phaseolus vulgaris L. seeds.
PubMed:Nutritional evaluation of protein, phosphorus, calcium and magnesium bioavailability from lupin (Lupinus albus var. multolupa)-based diets in growing rats: effect of alpha-galactoside oligosaccharide extraction and phytase supplementation.
PubMed:Diagnosis and management of kidney involvement in Fabry disease.
PubMed:Identification of a novel alpha-galactosidase from the hyperthermophilic archaeon Sulfolobus solfataricus.
PubMed:Extracellular alpha-galactosidase from Debaryomyces hansenii UFV-1 and its use in the hydrolysis of raffinose oligosaccharides.
PubMed:Enzymatic degradation of oligosaccharides in pinto bean flour.
PubMed:Oligosaccharins of black gram (Vigna mungo L.) as affected by processing methods.
PubMed:[Clinical development of agalsidase-beta for the treatment of Fabry disease.].
PubMed:Biological properties of fructooligosaccharides with different contents of kestose and nystose in rats.
PubMed:Increasing the transglycosylation activity of alpha-galactosidase from Bifidobacterium adolescentis DSM 20083 by site-directed mutagenesis.
PubMed:Reverse reaction of Aspergillus niger APC-9319 alpha-galactosidase in a supersaturated substrate solution: production of alpha-linked galactooligosaccharide (alpha-GOS).
PubMed:Use of an alpha-galactosidase gene as a food-grade selection marker for Streptococcus thermophilus.
PubMed:Gastrointestinal manifestations of Fabry disease: clinical response to enzyme replacement therapy.
PubMed:Measurement of renal function in patients with Fabry disease.
PubMed:Reduction of non-digestible oligosaccharides in soymilk: application of engineered lactic acid bacteria that produce alpha-galactosidase.
PubMed:Alpha and beta-galactosidase activities and oligosaccharide content in peanuts.
PubMed:Reduction of alpha-galactooligosaccharides in soyamilk by Lactobacillus fermentum CRL 722: in vitro and in vivo evaluation of fermented soyamilk.
PubMed:Enzyme replacement therapy for Fabry disease: lessons from two alpha-galactosidase A orphan products and one FDA approval.
PubMed:Effect of pH on Lactobacillus fermentum growth, raffinose removal, alpha-galactosidase activity and fermentation products.
PubMed:Agalsidase: a second look. With hindsight: full data challenge efficacy.
PubMed:In vitro evaluation of the fermentation properties of galactooligosaccharides synthesised by alpha-galactosidase from Lactobacillus reuteri.
PubMed:Synthesis of alpha-galactooligosaccharides with alpha-galactosidase from Lactobacillus reuteri of canine origin.
PubMed:Methylobacterium sp. isolated from a Finnish paper machine produces highly pyruvated galactan exopolysaccharide.
PubMed:Influence of ethylene inhibition by 1-methylcyclopropene on apricot quality, volatile production, and glycosidase activity of low- and high-aroma varieties of apricots.
PubMed:New products highlight ambiguity of orphan drug law.
PubMed:Novel food-grade plasmid vector based on melibiose fermentation for the genetic engineering of Lactococcus lactis.
PubMed:Purification and characterization of a thermostable alpha-galactosidase from Thermoanaerobacterium polysaccharolyticum.
PubMed:The effect of enzyme treatment of soybean meal on oligosaccharide disappearance and chick growth performance.
PubMed:Regioselectivity of enzymatic glycosylation of 6-O-acyl glycosides in supersaturated solutions.
PubMed:Effects of soybean (Glycine max) germination on biologically active components, nutritional values of seeds, and biological characteristics in rats.
PubMed:Transglycosidase activity of Bifidobacterium adolescentis DSM 20083 alpha-galactosidase.
PubMed:Enzymatic transformations in supersaturated substrate solutions: II. Synthesis of disaccharides via transglycosylation.
PubMed:[Effect of malting and thermoplastic extrusion on the technologic quality of soybean-derived products].
PubMed:alpha-Galactosidases of Penicillium simplicissimum: production, purification and characterization of the gene encoding AGLI.
PubMed:Effect of water activity on hydrolytic enzyme production by Fusarium moniliforme and Fusarium proliferatum during colonisation of maize.
PubMed:Circadian rhythm of breath hydrogen in young women.
PubMed:Thermostable alpha-galactosidase from Thermotoga neapolitana: cloning, sequencing and expression.
PubMed:Characterization of Bifidobacterium strains for use in soymilk fermentation.
PubMed:Substrate specificities of Penicillium simplicissimum alpha-galactosidases.
PubMed:Factors regulating production of alpha-galactosidase from Bacillus sp. JF2.
PubMed:Glucoamylase gene fusions alleviate limitations for protein production in Aspergillus awamori at the transcriptional and (post) translational levels.
PubMed:Three alpha-galactosidase genes of Trichoderma reesei cloned by expression in yeast.
PubMed:Analysis of heterologous protein production in defined recombinant Aspergillus awamori strains.
PubMed:An acetylglucomannan esterase of Aspergillus oryzae; purification, characterization and role in the hydrolysis of O-acetyl-galactoglucomannan.
PubMed:Digalactosylceramide is the receptor for staphylococcal enterotoxin-B in human kidney proximal tubular cells.
PubMed:Viability and enzymatic activity of bifidobacteria in milk.
PubMed:Effect of enzyme supplementation on the nutritional value of raw, autoclaved, and dehulled lupins (Lupinus albus) in chicken diets.
PubMed:Hydrolysis of raffinose and stachyose in cowpea (Vigna unguiculata) flour, using α-galactosidase fromAspergillus niger.
PubMed:Detection of Bifidobacterium species by enzymatic methods.
PubMed:The construction of recombinant industrial yeasts free of bacterial sequences by directed gene replacement into a nonessential region of the genome.
PubMed:Effects of Temperature and Relative Humidity on the Growth of and Enzyme Production by Actinomucor taiwanensis during Sufu Pehtze Preparation.
PubMed:[Microbial alpha-galactosidase (a review)].
PubMed:Degradation of the endosperm cell walls of Lactuca sativa L., cv. grand rapids in relation to the mobilisation of proteins and the production of hydrolytic enzymes in the axis, cotyledons and endosperm.
PubMed:Changes in carbohydrates and the activity of alpha-galactosidase, pentosanase and lipase during germination of groundnuts (Arachis hypogen).
PubMed:The use of alpha-galactosidase and invertase in hollow fiber reactors.
PubMed:Alpha-galactosidase production and use in a hollow-fiber reactor.
PubMed:Alpha-galactosidase activity of fungi on intestinal gas-forming peanut oligosaccharides.
 
Notes:
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