EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

pancrelipase (amylase;lipase;protease)
lipase of pancreas

Supplier Sponsors

CAS Number: 53608-75-6
Other(deleted CASRN):71060-52-1
ECHA EC Number:258-659-7
FDA UNII: FQ3DRG0N5K
Category:enzyme preparations and microorganisms
 
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Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
American Laboratories
Pancrelipase USP Powder 350
American Laboratories
Pancrelipase USP Powder 77B
American Laboratories
Pancrelipase USP Powder 84B
BOC Sciences
For experimental / research use only.
Pancrelipase
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
enzyme preparations and microorganisms
Recommendation for pancrelipase (amylase;lipase;protease) usage levels up to:
 not for fragrance use.
 
Recommendation for pancrelipase (amylase;lipase;protease) flavor usage levels up to:
 not for flavor use.
 
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EPA Substance Registry Services (TSCA):53608-75-6
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Chemidplus:0053608756
 
References:
Canada Domestic Sub. List:53608-75-6
Pubchem (sid):135335781
 
Other Information:
HMDB (The Human Metabolome Database):Search
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Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 pancrelipase
Search PMC Picture
 
Synonyms:
 amylases mixture with endopeptidases and lipase
 cotazym-S
 lipase of pancreas
 

Articles:

PubMed:[Efficiency of etiologic correction of concomitant ascaridosis in the complex treatment of chronic pancreatitis].
PubMed:Hypoparathyroidism after Roux-en-Y gastric bypass--a challenge for clinical management: a case report.
PubMed:Nutrition and pancreatic enzyme intake in patients with cystic fibrosis with distal intestinal obstruction syndrome.
PubMed:Efficacy and safety of a unique enteric-coated bicarbonate-buffered pancreatic enzyme replacement therapy in children and adults with cystic fibrosis.
PubMed:Long-term experience with ZENPEP in infants with exocrine pancreatic insufficiency associated with cystic fibrosis.
PubMed:Disruption of protein-tyrosine phosphatase 1B expression in the pancreas affects β-cell function.
PubMed:Pancreatic enzyme supplementation improves the incretin hormone response and attenuates postprandial glycemia in adolescents with cystic fibrosis: a randomized crossover trial.
PubMed:The effect of oral pancreatic enzyme supplementation on the course and outcome of acute pancreatitis: a randomized, double-blind parallel-group study.
PubMed:Characterization of a novel cross-linked lipase: impact of cross-linking on solubility and release from drug product.
PubMed:Efficacy of a Creon delayed-release pancreatic enzyme protocol for clearing occluded enteral feeding tubes.
PubMed:Off label pharmacological therapy in patients with short bowel syndrome.
PubMed:Diagnosis and treatment of pancreatic exocrine insufficiency.
PubMed:Lipid classes and fatty acid regiodistribution in triacylglycerols of seed oils of two Sambucus species (S. nigra L. and S. ebulus L.).
PubMed:Synchronous triple cancers of the pancreas, stomach, and cecum treated with S-1 followed by pancrelipase treatment of pancreatic exocrine insufficiency.
PubMed:Pancreatic lipase inhibitory gallotannins from Galla Rhois with inhibitory effects on adipocyte differentiation in 3T3-L1 cells.
PubMed:Effects of pancrelipase on nonalcoholic fatty liver disease after pancreaticoduodenectomy.
PubMed:Pancreatic enzyme replacement therapy for enterally fed patients with cystic fibrosis.
PubMed:Comparison of various solutions to dissolve critical care diet clots.
PubMed:Retrospective analysis to investigate the effect of concomitant use of gastric acid-suppressing drugs on the efficacy and safety of pancrelipase/pancreatin (CREON®) in patients with pancreatic exocrine insufficiency.
PubMed:A 51-week, open-label clinical trial in India to assess the efficacy and safety of pancreatin 40000 enteric-coated minimicrospheres in patients with pancreatic exocrine insufficiency due to chronic pancreatitis.
PubMed:Suspected isolated pancreatic enzyme deficiencies in dogs.
PubMed:Delayed small bowel transit in children with cystic fibrosis and pancreatic insufficiency.
PubMed:The growing pancreatic duct ligated pig as a model for exocrine pancreatic insufficiency in children: investigations to achieve sufficient vitamin A and vitamin E supply.
PubMed:Stimulating effect of pancreatic-like enzymes on the development of the gastrointestinal tract in piglets.
PubMed:Exocrine pancreatic insufficiency following esophagectomy.
PubMed:Cost-effectiveness analysis of pancreatin minimicrospheres in patients with pancreatic exocrine insufficiency due to chronic pancreatitis.
PubMed:Effect of an aqueous extract of Cucurbita ficifolia Bouché on the glutathione redox cycle in mice with STZ-induced diabetes.
PubMed:Liver iron and serum ferritin levels are misleading for estimating cardiac, pancreatic, splenic and total body iron load in thalassemia patients: factors influencing the heterogenic distribution of excess storage iron in organs as identified by MRI T2*.
PubMed:Pancrelipase: an evidence-based review of its use for treating pancreatic exocrine insufficiency.
PubMed:Randomised clinical trial: the efficacy and safety of pancreatin enteric-coated minimicrospheres (Creon 40000 MMS) in patients with pancreatic exocrine insufficiency due to chronic pancreatitis--a double-blind, placebo-controlled study.
PubMed:Pertzye approved for pancreatic insufficiency.
PubMed:Antiatherogenic properties of acetone extract of Alpinia zerumbet seeds.
PubMed:Review: Management of postprandial diarrhea syndrome.
PubMed:HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13.
PubMed:Sigma receptor binding of tetrabenazine series tracers targeting VMAT2 in rat pancreas.
PubMed:Pancrelipase delayed-release capsules for the treatment of pancreatic insufficiency.
PubMed:Pancreatic enzyme supplementation.
PubMed:Treatment of infants and toddlers with cystic fibrosis-related pancreatic insufficiency and fat malabsorption with pancrelipase MT.
PubMed:Evaluation of stool collections to measure efficacy of PERT in subjects with exocrine pancreatic insufficiency.
PubMed:Efficacy and safety of PANCREAZE® for treatment of exocrine pancreatic insufficiency due to cystic fibrosis.
PubMed:Administration of CREON® pancrelipase pellets via gastrostomy tube is feasible with no loss of gastric resistance or lipase activity: an in vitro study.
PubMed:Derivation and characterization of Chinese human embryonic stem cell line with high potential to differentiate into pancreatic and hepatic cells.
PubMed:Pancreatic enzyme products: digesting the changes.
PubMed:Efficacy of agents to prevent and treat enteral feeding tube clogs.
PubMed:Mitochondria as potential targets in antidiabetic therapy.
PubMed:Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans.
PubMed:A 6-month, open-label clinical trial of pancrelipase delayed-release capsules (Creon) in patients with exocrine pancreatic insufficiency due to chronic pancreatitis or pancreatic surgery.
PubMed:Some clinical evidence of the hypothesis of an indirect antiviral effect of propranolol through immunoactivation.
PubMed:Acute pancreatitis in obesity: adipokines and dietary fish oil.
PubMed:Efficacy of a novel pancreatic enzyme product, EUR-1008 (Zenpep), in patients with exocrine pancreatic insufficiency due to chronic pancreatitis.
PubMed:In brief: pancreatic enzyme products.
PubMed:Pancrelipase for pancreatic disorders: An update.
PubMed:An estimation of the manganese requirement for broilers from 1 to 21 days of age.
PubMed:Efficacy and Safety of a New Formulation of Pancrelipase (Ultrase MT20) in the Treatment of Malabsorption in Exocrine Pancreatic Insufficiency in Cystic Fibrosis.
PubMed:[Differentiated approaches to the treatment of chronic pancreatitis patients with metabolic syndrome].
PubMed:Folding, quality control, and secretion of pancreatic ribonuclease in live cells.
PubMed:CREON (Pancrelipase Delayed-Release Capsules) for the treatment of exocrine pancreatic insufficiency.
PubMed:Isolation of a novel catechin from Bergenia rhizomes that has pronounced lipase-inhibiting and antioxidative properties.
PubMed:The impact of pancreatic enzyme supplementation on postprandial responses of glucagon-like Peptide-2 in patients with chronic pancreatitis and pancreatic exocrine insufficiency.
PubMed:Constitutively active heat shock factor 1 enhances glucose-driven insulin secretion.
PubMed:Exocytosis, dependent on Ca2+ release from Ca2+ stores, is regulated by Ca2+ microdomains.
PubMed:Anti-diabetic effects including diabetic nephropathy of anti-osteoporotic trace minerals on diabetic mice.
PubMed:Pancrelipase delayed-release capsules (CREON) for exocrine pancreatic insufficiency due to chronic pancreatitis or pancreatic surgery: A double-blind randomized trial.
PubMed:[Efficacy and safety of pancrealipase delayed-release capsules (Creon) in patients with pancreatic insufficiency due to chronic pancreatitis or pancreatic surgery].
PubMed:FDA approves third pancrelipase product: Unapproved products illegal to market after April 28.
PubMed:Safety and tolerability of a new formulation of pancrelipase delayed-release capsules (CREON) in children under seven years of age with exocrine pancreatic insufficiency due to cystic fibrosis: an open-label, multicentre, single-treatment-arm study.
PubMed:Genetic polymorphisms of ADRB2 and IL10 may be associated with the risk of IgE sensitization to digestive powders in exposed medical personnel.
PubMed:Dynamic regulation of CFTR bicarbonate permeability by [Cl-]i and its role in pancreatic bicarbonate secretion.
PubMed:Oral pancreatic enzyme substitution therapy in chronic pancreatitis: is clinical response an appropriate marker for evaluation of therapeutic efficacy?
PubMed:Efficacy and tolerability of a new formulation of pancrelipase delayed-release capsules in children aged 7 to 11 years with exocrine pancreatic insufficiency and cystic fibrosis: a multicenter, randomized, double-blind, placebo-controlled, two-period crossover, superiority study.
PubMed:Efficacy and safety of Creon 24,000 in subjects with exocrine pancreatic insufficiency due to cystic fibrosis.
PubMed:Delayed release pancrelipase for treatment of pancreatic exocrine insufficiency associated with chronic pancreatitis.
PubMed:EUR-1008 pancreatic enzyme replacement is safe and effective in patients with cystic fibrosis and pancreatic insufficiency.
PubMed:Pharmacokinetics of erlotinib for the treatment of high-grade glioma in a pediatric patient with cystic fibrosis: case report and review of the literature.
PubMed:Efficacy and tolerability of Creon for Children in infants and toddlers with pancreatic exocrine insufficiency caused by cystic fibrosis: an open-label, single-arm, multicenter study.
PubMed:First FDA-approved pancrelipase product may mark new era for providers, patients.
PubMed:Antidiabetogenic constituents from the Thai traditional medicine Cotylelobium melanoxylon.
PubMed:[Experience with the use of 13C-breath test for the evaluation of the efficacy of enzyme substitution therapy with microencapsulated pancreatinin in patients with severe primary pancreatic insufficiency].
PubMed:Delayed release pancrelipase for the treatment of pancreatic exocrine insufficiency associated with cystic fibrosis.
PubMed:Pancreatic enzyme replacement therapy for young cystic fibrosis patients.
PubMed:Eupatilin, isolated from Artemisia princeps Pampanini, enhances hepatic glucose metabolism and pancreatic beta-cell function in type 2 diabetic mice.
PubMed:Cetilistat (ATL-962), a novel pancreatic lipase inhibitor, ameliorates body weight gain and improves lipid profiles in rats.
PubMed:Conversion of sunflower oil to biodiesel by alcoholysis using immobilized lipase.
PubMed:Salacia root, a unique Ayurvedic medicine, meets multiple targets in diabetes and obesity.
PubMed:[Chronic pancreatitis: comparative assessment of effectiveness of dose-dependent therapy and prophylaxis of recurrence by polyenzyme drugs].
PubMed:Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice.
PubMed:CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells.
PubMed:Effect of liquid pancreatic enzymes on the assimilation of fat in different liquid formula diets.
PubMed:High-performance liquid chromatography/electrospray ionization tandem mass spectrometry for characterization of enzymatic degradation of 2,2'-bis(2-oxazoline)-linked poly-epsilon-caprolactone.
PubMed:New concepts in the management of adverse drug reactions.
PubMed:In vitro comparative study of three pancreatic enzyme preparations: dissolution profiles, active enzyme release and acid stability.
PubMed:Pancreatic enzyme pharmacotherapy.
PubMed:Construction and identification of human tissue kallikrein gene eukaryotic expressing vector.
PubMed:In Vitro Comparison of Physical Parameters, Enzyme Activity, Acid Resistance, and pH Dissolution Characteristics of Enteric-Coated Pancreatic Enzyme Preparations: Implications for Clinical Variability and Pharmacy Substitution.
PubMed:In vivo suppression of mafA mRNA with siRNA and analysis of the resulting alteration of the gene expression profile in mouse pancreas by the microarray method.
PubMed:Lipases and lipolysis in the human digestive tract: where do we stand?
PubMed:Efficacy of lower than standard doses of pancreatic enzyme supplementation therapy during acid inhibition in patients with pancreatic exocrine insufficiency.
PubMed:The effects of oral pancreatic enzymes (Creon 10 capsule) on steatorrhea: a multicenter, placebo-controlled, parallel group trial in subjects with chronic pancreatitis.
PubMed:Medical nutrition therapy for cystic fibrosis: beyond pancreatic enzyme replacement therapy.
PubMed:An enteric-coated high-buffered pancrelipase reduces steatorrhea in patients with cystic fibrosis: a prospective, randomized study.
PubMed:Identification of novel saponins from edible seeds of Japanese horse chestnut (Aesculus turbinata Blume) after treatment with wooden ashes and their nutraceutical activity.
PubMed:Enteric-coated pancreatic enzyme with bicarbonate is equal to standard enteric-coated enzyme in treating malabsorption in cystic fibrosis.
PubMed:Immobilization of pancreatic lipase on chitin and chitosan.
PubMed:Immobilization of pancreatic lipase on polyvinyl alcohol by cyanuric chloride.
PubMed:Fibrosing colonopathy in a man with cystic fibrosis on pancreatic enzyme supplements.
PubMed:Expression of a fibroblast growth factor-binding protein during the development of adenocarcinoma of the pancreas and colon.
PubMed:[Isolation of pancreatic lipase activity-inhibitory component of spirulina platensis and it reduce postprandial triacylglycerolemia].
PubMed:Analyses of Pseudomonas aeruginosa lectin binding to alpha-galactosylated glycans.
PubMed:[Does enzyme substitution therapy reduce pain in chronic pancreatitis?].
PubMed:Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus.
PubMed:[The role of orlistat in the treatment of obesity].
PubMed:Combining unprotected pancreatic enzymes with pH-sensitive enteric-coated microspheres does not improve nutrient digestion in patients with cystic fibrosis.
PubMed:Enzyme content and acid stability of enteric-coated pancreatic enzyme products in vitro.
PubMed:Skin prick test reactivity to supplemental enzymes in cystic fibrosis and pancreatic insufficiency.
PubMed:The secretagogue effect of the poison from Centruroides limpidus limpidus on the pancreas of mice and the antagonistic action of the Bouvardia ternifolia extract.
PubMed:Determination of the kinetic properties of platycodin D for the inhibition of pancreatic lipase using a 1,2-diglyceride-based colorimetric assay.
PubMed:CCK-B receptor antagonist YF476 inhibits pancreatic enzyme secretion at a duodenal level in pigs.
PubMed:Lymphatic vessel density and vascular endothelial growth factor-C expression correlate with malignant behavior in human pancreatic endocrine tumors.
PubMed:Creon 10,000 Minimicrospheres vs. Creon 8,000 microspheres--an open randomised crossover preference study.
PubMed:Fibrosing colonopathy in an adult cystic fibrosis patient after discontinuing pancreatic enzyme therapy.
PubMed:A high prevalence of organ-specific autoimmunity in patients with bipolar disorder.
PubMed:Omega-3 fatty acids improve liver and pancreas function in postoperative cancer patients.
PubMed:In vitro studies of the effects of HAART drugs and excipients on activity of digestive enzymes.
PubMed:The extracellular cyclic AMP-adenosine pathway in renal physiology.
PubMed:In vitro influence of spices and spice-active principles on digestive enzymes of rat pancreas and small intestine.
PubMed:5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone: a pancreatic lipase inhibitor isolated from Alpinia officinarum.
PubMed:The enzyme levels in blood are not affected by oral administration of a pancreatic enzyme preparation (Creon 10,000) in pancreas-insufficient pigs.
PubMed:Unusual expression of the F9 gene in peripheral lymphocytes hinders investigation of F9 mRNA in hemophilia B patients.
PubMed:Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control.
PubMed:So you have a clogged feeding tube, now what?
PubMed:Recent progress in freeze-fracturing of high-pressure frozen samples.
PubMed:Determination of folate concentrations in pulses by a microbiological method employing trienzyme extraction.
PubMed:Inhibitory effects of human and porcine alpha-amylase on CCK-8-stimulated lipase secretion of isolated rat pancreatic acini.
PubMed:Functional tolerance is maintained despite proliferation of CD4 T cells after encounter with tissue-derived antigen.
PubMed:Controversies in clinical pancreatology: management of acute idiopathic recurrent pancreatitis.
PubMed:Flow injection chemiluminescent assays for glycerol and triglycerides using a co-immobilized enzyme reactor.
PubMed:Regulation of translation initiation by insulin and amino acids in skeletal muscle of neonatal pigs.
PubMed:Selective decreases in amphetamine self-administration and regulation of dopamine transporter function in diabetic rats.
PubMed:Structural characterization of triacylglycerol in several oils containing gamma-linolenic acid.
PubMed:Digestive stimulant action of three Indian spice mixes in experimental rats.
PubMed:Structure and composition of the fusion pore.
PubMed:Synthetic and novel biocatalytic resolution studies on (+/-)-5/6/7-acetoxy-4-aryl-3,4-dihydrocoumarins.
PubMed:Pancreatic metallothionein-I may play a role in zinc homeostasis during maternal dietary zinc deficiency in mice.
PubMed:The development of a clinical syndrome of asymptomatic pancreatitis and eosinophilia after treatment with clozapine in schizophrenia: implications for clinical care, recognition and management.
PubMed:[Conservative therapy of chronic pancreatitis].
PubMed:Ranitidine and omeprazole as adjuvant therapy to pancrelipase to improve fat absorption in patients with cystic fibrosis.
PubMed:Growth factors in pancreatic health and disease.
PubMed:Pancreatic toxicity after liposomal amphotericin B.
PubMed:The effect of ginseng on bile-pancreatic secretion in the rat. Increase in proteins and inhibition of total lipids and cholesterol secretion.
PubMed:[Enzyme-based drugs in pancreatic diseases].
PubMed:Regiospecific analysis of neutral ether lipids by liquid chromatography/electrospray ionization/single quadrupole mass spectrometry: validation with synthetic compounds.
PubMed:Further comments on fibrosing colonpathy study.
PubMed:Postcibal gastric emptying of pancreatin pellets: effects of dose and meal oil.
PubMed:Efficacy of oral pancreatic enzyme therapy for the treatment of fat malabsorption in HIV-infected patients.
PubMed:Dissolution of an esophageal bezoar with pancreatic enzyme extract.
PubMed:Lipase catalysed synthesis of optically enriched alpha-haloamides.
PubMed:Are minimicrosphere pancrelipase capsules effective enough for the treatment of pancreatic steatorrhea?
PubMed:Cyclic and linear peptides derived from alpha-amylase inhibitory protein tendamistat.
PubMed:Molecular cloning of preproinsulin cDNAs from several osteoglossomorphs and a cyprinid.
PubMed:Pancreatic enzyme replacement therapy.
PubMed:Amino-acid substitutions at the fully exposed P1 site of bovine pancreatic trypsin inhibitor affect its stability.
PubMed:Cloned neuropeptide Y (NPY) Y1 and pancreatic polypeptide Y4 receptors expressed in Chinese hamster ovary cells show considerable agonist-driven internalization, in contrast to the NPY Y2 receptor.
PubMed:Identification of a nitric oxide-regulated zinc finger containing transcription factor using motif-directed differential display.
PubMed:Defective dietary fat processing in transgenic mice lacking aquaporin-1 water channels.
PubMed:Diet stimulation as a synergistic factor of aggravation in a pancreatic bile duct ligation-induced rat pancreatitis model.
PubMed:Comparison of two enteric coated microsphere preparations in the treatment of pancreatic exocrine insufficiency caused by cystic fibrosis.
PubMed:Fate of 2-deoxy-2-[18F]fluoro-D-glucose in hyperglycemic rats.
PubMed:Assessment of the effectiveness of drug therapies on nutritional status in the elderly: "concerning a randomised, double-blind clinical study of the activity of pancreatic extracts and a placebo during the renutrition of elderly subjects suffering from protein caloric undernutrition".
PubMed:Prevention of diabetes mellitus in the non-obese diabetic mouse strain with monoclonal antibodies against the CD45RB molecule.
PubMed:A comparison of the efficacy and tolerance of pancrelipase and placebo in the treatment of steatorrhea in cystic fibrosis patients with clinical exocrine pancreatic insufficiency.
PubMed:Pancrelipase for treatment-refractory diarrhea associated with nelfinavir.
PubMed:Management of protease inhibitor-associated diarrhea.
PubMed:Genomic structure, expression, and chromosomal localization of the human glycine N-methyltransferase gene.
PubMed:Synthesis and study of a lipophilic alpha-keto amide inhibitor of pancreatic lipase.
PubMed:Enzymatic desymmetrization of a meso polyol corresponding to the C(19)-C(27) segment of rifamycin S.
PubMed:The effect of severe undernutrition, and subsequent refeeding on digestive function in human patients.
PubMed:Influence of dietary spices and their active principles on pancreatic digestive enzymes in albino rats.
PubMed:Acquired segmental megacolon in an adult patient with cystic fibrosis.
PubMed:Critical role of micelles in pancreatic lipase activation revealed by small angle neutron scattering.
PubMed:A TROSY CPMG sequence for characterizing chemical exchange in large proteins.
PubMed:Topology, subcellular localization, and sequence diversity of the Mlo family in plants.
PubMed:Prospective, long-term study of fat-soluble vitamin status in children with cystic fibrosis identified by newborn screen.
PubMed:Autoimmune insulitis and diabetes in the absence of antigen-specific contact between T cells and islet beta-cells.
PubMed:Enzymatic therapy in patients with chronic pancreatitis.
PubMed:Pancreatic supplements reduce symptomatic response of healthy subjects to a high fat meal.
PubMed:Pancreatic enzymes and fibrosing colonopathy.
PubMed:Colonic wall thickness, pancreatic enzyme dose and type of preparation in cystic fibrosis.
PubMed:Faecal bile acid and dietary residue excretion in cystic fibrosis: age group variations.
PubMed:Effects of pancreatic enzyme preparations on erythrocyte glutathione peroxidase activities and plasma selenium concentrations in cystic fibrosis.
PubMed:Exocrine pancreatic insufficiency in a cat.
PubMed:Fat gram target.
PubMed:Mismatch of duodenal deliveries of dietary fat and pancreatin from enterically coated microspheres.
PubMed:Is fibrosing colonopathy an immune mediated disease?
PubMed:13Carbon mixed triglyceride breath test and pancreatic enzyme supplementation in cystic fibrosis.
PubMed:Comparative evaluation of a high lipase pancreatic enzyme preparation and a standard pancreatic supplement for treating exocrine pancreatic insufficiency in chronic pancreatitis.
PubMed:Response to a single oral dose of all-rac-alpha-tocopheryl acetate in patients with cystic fibrosis and in healthy individuals.
PubMed:Utility of pancreatic digestive enzyme immunohistochemistry in the differential diagnosis of hepatocellular carcinoma, cholangiocarcinoma and metastatic adenocarcinoma of the liver.
PubMed:Management of malabsorption in cystic fibrosis: influence of recent developments on clinical practice.
PubMed:Stable isotope studies of pancreatic enzyme release in vivo.
PubMed:Fibrosing colonopathy in children with cystic fibrosis.
PubMed:[Differential therapy of exocrine pancreatic insufficiency--current aspects and future prospects of substitution therapy with pancreatic enzymes].
PubMed:Gut inflammation in children with cystic fibrosis on high-dose enzyme supplements.
PubMed:Fibrosing colonopathy in cystic fibrosis: results of a case-control study.
PubMed:Faecal interleukin-8 and tumour necrosis factor-alpha concentrations in cystic fibrosis.
PubMed:Chronic metabolic alkalosis: not uncommon in young children with severe cystic fibrosis.
PubMed:Pancolonic disease in cystic fibrosis and high-dose pancreatic enzyme therapy.
PubMed:Comparative effects of adjuvant cimetidine and omeprazole during pancreatic enzyme replacement therapy.
PubMed:Strictures of ascending colon in cystic fibrosis and high-strength pancreatic enzymes.
PubMed:[Comparative clinical study of Neopanpur and Creon].
PubMed:Pancreatic extract lipase activity.
PubMed:Comparative in vitro and in vivo studies of enteric-coated pancrelipase preparations for pancreatic insufficiency.
PubMed:Fat absorption and gastroenteric pH profile in postsurgical pancreatic insufficiency: role of the association of H2-receptor antagonists with pancreatic enzymes.
PubMed:[Long-term treatment of mucoviscidosis. Results with a microencapsulated pancreatic enzyme preparation].
PubMed:Chronic pancreatitis.
PubMed:Enteral pancreatic enzyme feedback inhibition of the exocrine secretion of the human transplanted pancreas.
PubMed:Comparison between a standard pancreatic supplement and a high enzyme preparation in cystic fibrosis.
PubMed:A comparison of two pancreatin microsphere preparations in cystic fibrosis.
PubMed:Pancreatic enzyme supplements in cystic fibrosis.
PubMed:Pancreatic enzyme supplement dosage in cystic fibrosis.
PubMed:Inactivation of gastric and pancreatic lipases by diethyl p-nitrophenyl phosphate.
PubMed:Treatment failure after substitution of generic pancrelipase capsules.
PubMed:Postoperative management of patients with total exocrine pancreatic insufficiency.
PubMed:Regulatory status of pancreatic enzyme preparations.
PubMed:Treatment failure after substitution of generic pancrelipase capsules. Correlation with in vitro lipase activity.
PubMed:Unclogging feeding tubes with pancreatic enzyme.
PubMed:The active site composition of porcine pancreatic lipase: possible involvement of lysine.
PubMed:Pancreatic enzyme replacement therapy.
PubMed:Effect of pancreatic enzyme supplements on iron absorption.
PubMed:Human pancreatic graft fistula exocrine suppression by oral pancreatic enzymes.
PubMed:Pancreatic enzyme replacement therapy. Importance of gastric acid secretion, H2-antagonists, and enteric coating.
PubMed:Pancreatic enzyme replacement therapy in post-pancreatectomy patients.
PubMed:Development of pancreatic enzyme microsphere technology and US findings with Pancrease in the treatment of chronic pancreatitis.
PubMed:Correction of malnutrition and maldigestion with enzyme supplementation in patients with surgical suppression of exocrine pancreatic function.
PubMed:Duodenal instillation of pancreatin does not abolish steatorrhea in patients with pancreatic insufficiency.
PubMed:Critical examination of therapeutic efficacy of a pH-sensitive enteric-coated pancreatic enzyme preparation in treatment of exocrine pancreatic insufficiency secondary to cystic fibrosis.
PubMed:Use of pancreatic Schilling test to determine efficiency of pancreatic enzyme delivery in pancreatic insufficiency.
PubMed:Renal handling of 125I-labelled homologous pancreatic lipase and amylase in the rat.
PubMed:[Comparative study of the effect of kreon and cotazyme forte in children with cystic fibrosis].
PubMed:The management of enzymatic therapy in cystic fibrosis patients by an individualized approach.
PubMed:Malabsorption in cystic fibrosis: mechanisms and treatment.
PubMed:Pancrease gastroresistance: in vitro evaluation of pH-determined dissolution.
PubMed:Nutritional management and pancreatic enzyme therapy in cystic fibrosis patients: state of the art in 1987 and projections into the future.
PubMed:Efficacy of pancrease: crossover comparative study versus eurobiol in cystic fibrosis.
PubMed:Efficacy of pancreatic enzyme supplementation in children with cystic fibrosis: comparison of two preparations by random crossover study and a retrospective study of the same patients at two different ages.
PubMed:In vivo and in vitro studies of microsphere pancreatic supplements.
PubMed:Comparison of gastrointestinal pH in cystic fibrosis and healthy subjects.
PubMed:Human asthma due to a dog's drugs.
PubMed:Enteral feedback control of pancreatic hypertrophy: the role of pancreatic biliary secretions.
PubMed:Hypoalbuminemia at diagnosis as a marker for severe respiratory course in infants with cystic fibrosis identified by newborn screening.
PubMed:Change in enzyme content and manufacturer of Viokase.
PubMed:Management of maldigestion associated with pancreatic insufficiency.
PubMed:An in vitro animal model for the study of cereal components toxic in celiac disease.
PubMed:Management of short-bowel syndrome.
PubMed:Pancreatic supplementation in end-stage renal disease.
PubMed:[Medical treatment of a gastric bezoar].
PubMed:Incidence of distal intestinal obstruction syndrome in cystic fibrosis.
PubMed:Recurrent gastric bezoars. A new approach to treatment and prevention.
PubMed:Comparative evaluation of the therapeutic efficacy of a pH-sensitive enteric coated pancreatic enzyme preparation with conventional pancreatic enzyme therapy in the treatment of exocrine pancreatic insufficiency.
PubMed:The pH-sensitive enteric-coated pancreatic enzyme preparations: an evaluation of therapeutic efficacy in adult patients with pancreatic insufficiency.
PubMed:Metal-binding ligands in Viokase.
PubMed:Comparison of effectiveness of pancreatic enzyme preparations in cystic fibrosis.
PubMed:Pancreatic supplements.
PubMed:Comparative in vitro enzyme activities of five commercially available pancreatic supplements.
PubMed:Comparative trial of viokase, pancreatin and Pancrease pancrelipase (enteric coated beads) in the treatment of malabsorption in cystic fibrosis.
PubMed:Controversies in the treatment of exocrine pancreatic insufficiency.
PubMed:A clinical trial of amygdalin (Laetrile) in the treatment of human cancer.
PubMed:Comparison of two forms of enteric-coated pancrelipase In six teenagers with cystic fibrosis.
PubMed:Comparative study of varying regimens to improve steatorrhoea and creatorrhoea in cystic fibrosis: Effectiveness of an enteric-coated preparation with and without antacids and cimetidine.
PubMed:Oral correction of essential fatty acid deficiency in cystic fibrosis.
PubMed:Zinc-binding ligands in Viokase and role in zinc absorption.
PubMed:Clinical pharmacology for pediatricians. I. Pancreatic enzyme preparations, with special reference to enterically coated microspheres of pancrelipase.
PubMed:A mixed-triglyceride breath test for intraluminal fat digestive activity.
PubMed:Solubility of oral pancreatic enzyme supplement capsules in biological fluids.
PubMed:Effect of cimetidine and sodium bicarbonate on pancreatic replacement therapy in cystic fibrosis.
PubMed:Effect of cimetidine and pancreatic enzymes on serum and fecal bile acids and fat absorption in cystic fibrosis.
PubMed:Clinical Experiences in 14C-tripalmitin breath test for fat malabsorption.
PubMed:Action of human pancreatic lipase on synthetic mixed symmetrical triglycerides of long-chain acids and butyric acid.
PubMed:Case records of the Massachusetts General Hospital. Case 25-1961.
 
Notes:
a preparation of hog pancreatic enzymes standardized for lipase content.
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