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lidocaine hydrochloride monohydrate
acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, hydrochloride, hydrate (1:1:1)

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Name:[2-(2,6-dimethylanilino)-2-oxoethyl]-diethylazanium;chloride;hydrate
CAS Number: 6108-05-0Picture of molecule3D/inchi
FDA UNII: V13007Z41A
MDL:MFCD00150329
Molecular Weight:288.81765000
Formula:C14 H25 Cl N2 O2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Google Patents:Search
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PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 350.80 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000043 mmHg @ 25.00 °C. (est)
Flash Point: 331.00 °F. TCC ( 166.00 °C. ) (est)
logP (o/w): 2.359 (est)
Soluble in:
 water, 1473 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Lidocaine hydrochloride monohydrate 98%
Odor: characteristic
Use: Lidocaine hydrochloride monohydrate is the hydrochloride monohydrate form of lidocaine, which is an aminoethylamide and a prototypical member of the amide class anesthetics. It is a local anesthetic and cardiac depressant used as an antiarrhythmia agent. Lidocaine hydrochloride monohydrate is a local anesthetic and cardiac depressant used as an antiarrhythmia agent.
Charkit Chemical
LIDOCAINE HYDROCHLORIDE USP
Glentham Life Sciences
Lidocaine hydrochloride monohydrate, 98%
Glentham Life Sciences
Lidocaine hydrochloride monohydrate, EP grade
Penta International
LIDOCAINE HYDROCHLORIDE MONOHYDRATE USP
Santa Cruz Biotechnology
For experimental / research use only.
Lidocaine Hydrochloride Monohydrate ≥98%
Sigma-Aldrich: Sigma
For experimental / research use only.
Lidocaine hydrochloride monohydrate solid
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 292 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 179, Pg. 580, 1971.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for lidocaine hydrochloride monohydrate usage levels up to:
 not for fragrance use.
 
Recommendation for lidocaine hydrochloride monohydrate flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :22483
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
[2-(2,6-dimethylanilino)-2-oxoethyl]-diethylazanium;chloride;hydrate
Chemidplus:0006108050
RTECS:AN7700000 for cas# 6108-05-0
 
References:
 [2-(2,6-dimethylanilino)-2-oxoethyl]-diethylazanium;chloride;hydrate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):22483
Pubchem (sid):134986455
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
HMDB (The Human Metabolome Database):Search
MedlinePlusSupp:View
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, hydrochloride, hydrate (1:1:1)
 acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride, monohydrate
2',6'-acetoxylidide, 2-(diethylamino)-, hydrochloride, hydrate
 dalcaine
2-diethylamino-N-(2,6-dimethylphenyl)acetamide hydrochloride monohydrate
2-(diethylamino)-2',6'-acetoxylidide hydrochloride hydrate
2-(diethylamino)-2',6'-acetoxylidide monohydrochloride monohydrate
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride hydrate
2-(diethylamino)-n-(2,6-dimethylphenyl)acetamide monohydrochloride monohydrate
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide, oxamethane, chloride
 diethylaminoacet-2,6-xylidide hydrochloride monohydrate
[2-(2,6-dimethylanilino)-2-oxoethyl]-diethylazanium;chloride;hydrate
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide hydrochloride--water (1/1)
N-(2,6-dimethylphenyl)-N2,N2-diethylglycinamide hydrochloride hydrate
 dolicaine
 lidocaine hydrochloride anhydrous
 lidocaine hydrochloride hydrate
 lignocaine hydrochloride monohydrate
 xylocaine hydrochloride monohydrate
 xylocard
 xyloneural
 zingo
 

Articles:

PubMed:Study on patients who underwent suspected diagnosis of allergy to amide-type local anesthetic agents by the leukocyte migration test.
PubMed:Efficacy of articaine formulations: quantitative reviews.
PubMed:Evaluation of middle and distal esophageal diverticuli with transnasal esophagoscopy.
PubMed:Bi-hemispheric contribution to functional motor recovery of the affected forelimb following focal ischemic brain injury in rats.
PubMed:Local and regional anesthesia in ruminants and swine.
PubMed:Factors affecting the voluntary intake of food by sheep. 5. The inhibitory effect of hypertonicity in the rumen.
PubMed:Techniques of local analgesia in ruminants and swine.
PubMed:Stability of sterile aqueous lidocaine hydrochloride and epinephrine injections submitted by U.S. hospitals.
PubMed:Evaluation of preparations of patent blue (Alphazurine 2G) dye for parenteral use.
 
Notes:
None found
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