EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

epigallocatechin gallate
L-epigallocatechin gallate

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Name:[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
CAS Number: 989-51-5Picture of molecule3D/inchi
Other(deleted CASRN):863-65-0
Nikkaji Web:J134.058A
Beilstein Number:3658838
XlogP3:1.20 (est)
Molecular Weight:458.37666000
Formula:C22 H18 O11
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 222.00 to 224.00 °C. @ 760.00 mm Hg
Boiling Point: 909.00 to 910.00 °C. @ 760.00 mm Hg (est)
Flash Point: 608.00 °F. TCC ( 320.00 °C. ) (est)
logP (o/w): 0.639 (est)
Soluble in:
 water, 32.77 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antioxidants
Alfa Biotechnology
For experimental / research use only.
Epigallocatechin gallate 98%
BOC Sciences
For experimental / research use only.
Epigallocatechin Gallate
Odor: characteristic
Use: EGCG, also called Epigallocatechin gallate, under the IUPAC name [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate,
EMD Millipore
For experimental / research use only.
(–)-epiGallocatechin Gallate
For experimental / research use only.
(-)-Epigallocatechin gallate (HPLC) ≥98%
Inoveol® EGCG
Odor: characteristic
Use: Green tea benefits from a long term botanical tradition in Asia due to its fantastic preventive and protective effects on health. EGCG (EpigalloCatechin Gallate) is one of green tea most active molecule. Inoveol® EGCG is a new cosmetic dedicated form of EGCG: highly water soluble, stabilised and purified, this molecular sponge captures free radicals, detoxifies and prevents ageing.
Glentham Life Sciences
Epigallocatechin gallate
Nacalai USA
For experimental / research use only.
(-)-epiGallocatechin Gallate
O'Laughlin Industries
EGCG Natural 90
For experimental / research use only.
(-)-Epigallocatechin Gallate
analytical standard
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 2170 mg/kg
Kiso to Rinsho. Clinical Report. Vol. 21, Pg. 4601, 1987.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
Recommendation for epigallocatechin gallate usage levels up to:
 not for fragrance use.
Recommendation for epigallocatechin gallate flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific opinion on the safety of green tea catechins
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :65064
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
RTECS:KB5200000 for cas# 989-51-5
 [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):65064
Pubchem (sid):135021682
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C09731
HMDB (The Human Metabolome Database):HMDB03153
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
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 benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester
(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 3,4,5-trihydroxybenzoate
(-)-epigallocatechin 3-gallate
epigallocatechin 3-gallate
(-)-epigallocatechin 3-O-gallate
(-)-epigallocatechin gallate
L-epigallocatechin gallate
(-)-epigallocatechol gallate
 tea catechin


PubMed:Astringency is a trigeminal sensation that involves the activation of G protein-coupled signaling by phenolic compounds.
J-Stage:Human Serum Albumin as an Antioxidant in the Oxidation of (-)-Epigallocatechin Gallate: Participation of Reversible Covalent Binding for Interaction and Stabilization
PubMed:The impact of packaging materials on the antioxidant phytochemical stability of aqueous infusions of green tea (Camellia sinensis) and yaupon holly (Ilex vomitoria) during cold storage.
PubMed:Phenolic metabolites from honeybush tea (Cyclopia subternata).
antimutagen in green tea (camellia sinensis); a steroid 5alpha-reductase inhibitor. Present in black tea and green tea (Thea sinensis) Epigallocatechin gallate (EGCG) is the principal catechin in tea from Camellia sinensis, the most consumed beverage worldwide (after water). Depending on brew time and temperature, a single cup of green tea may contain 100-200 mg EGCG.
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