EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

levan
polyfructose produced by enzymatic action on sucrose

Supplier Sponsors

Name:5-[[5-[[3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4-dihydroxy-2-(hydroxymethyl)oxolan-2-yl]oxymethyl]-2-(hydroxymethyl)oxolane-2,3,4-triol
CAS Number: 9013-95-0Picture of molecule3D/inchi
FDA UNII: Search
MDL:MFCD00131502
XlogP3-AA:-6.00 (est)
Molecular Weight:504.44024000
Formula:C18 H32 O16
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:film forming agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 8.707e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data2
CosIng:cosmetic data
Cosmetic Uses: film formers
skin protecting agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Levan - from Jerusalem artichoke
Sigma-Aldrich: Sigma
For experimental / research use only.
Levan from Erwinia herbicola
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
film forming agents
Recommendation for levan usage levels up to:
 not for fragrance use.
 
Recommendation for levan flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the substantiation of a health claim related to “non digestible oligo and polysaccharides including galacto-oligosaccharides, oligofructose, polyfructose and inulin” and “increase in calcium absorption” pursuant to Article 14 of Regulation (EC) No 1924/2006
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5254051
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
5-[[5-[[3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4-dihydroxy-2-(hydroxymethyl)oxolan-2-yl]oxymethyl]-2-(hydroxymethyl)oxolane-2,3,4-triol
Chemidplus:0009013950
 
References:
 5-[[5-[[3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4-dihydroxy-2-(hydroxymethyl)oxolan-2-yl]oxymethyl]-2-(hydroxymethyl)oxolane-2,3,4-triol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5254051
Pubchem (sid):135258298
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C01355
HMDB (The Human Metabolome Database):HMDB03539
FooDB:FDB023192
VCF-Online:VCF Volatile Compounds in Food
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 erwinia herbicola
Search Trop Picture
 
Synonyms:
5-[[5-[[3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4-dihydroxy-2-(hydroxymethyl)oxolan-2-yl]oxymethyl]-2-(hydroxymethyl)oxolane-2,3,4-triol
 fructan
 polyfructose
 polyfructose produced by enzymatic action on sucrose
 

Articles:

PubMed:Cloning and heterologous expression of the ftfCNC-2(1) gene from Weissella confusa MBFCNC-2(1) as an extracellular active fructansucrase in Bacillus subtilis.
PubMed:From fructans to difructose dianhydrides.
PubMed:[Application of levansucrase in levan synthesis--a review].
PubMed:Current use of ultrasound transmission gel for transesophageal echocardiogram examinations: a survey of cardiothoracic anesthesiology fellowship directors.
PubMed:Exopolysaccharides synthesized by Lactobacillus reuteri protect against enterotoxigenic Escherichia coli in piglets.
PubMed:Biosynthesis of levan by levansucrase from Bacillus methylotrophicus SK 21.002.
PubMed:Levan production by Zymomonas mobilis in batch and continuous fermentation systems.
PubMed:Levan from Bacillus subtilis Natto: its effects in normal and in streptozotocin-diabetic rats.
PubMed:Functional characterization of sucrose phosphorylase and scrR, a regulator of sucrose metabolism in Lactobacillus reuteri.
PubMed:Properties of Geobacillus stearothermophilus levansucrase as potential biocatalyst for the synthesis of levan and fructooligosaccharides.
PubMed:Film forming microbial biopolymers for commercial applications-A review.
PubMed:Floral visitation by the Argentine ant reduces pollinator visitation and seed set in the coast barrel cactus, Ferocactus viridescens.
PubMed:The anti-obesity effects of the dietary combination of fermented red ginseng with levan in high fat diet mouse model.
PubMed:Microbial production of levanase for specific hydrolysis of levan.
PubMed:Exopolymer diversity and the role of levan in Bacillus subtilis biofilms.
PubMed:Identification of Lactobacillus curvatus TMW 1.624 dextransucrase and comparative characterization with Lactobacillus reuteri TMW 1.106 and Lactobacillus animalis TMW 1.971 dextransucrases.
PubMed:Structural analysis of fructans produced by acetic acid bacteria reveals a relation to hydrocolloid function.
PubMed:Fructanase and fructosyltransferase activity of non-Saccharomyces yeasts isolated from fermenting musts of Mezcal.
PubMed:Preparation, antioxidant and antitumor activities in vitro of different derivatives of levan from endophytic bacterium Paenibacillus polymyxa EJS-3.
PubMed:Purification and characterization of levansucrases from Bacillus amyloliquefaciens in intra- and extracellular forms useful for the synthesis of levan and fructooligosaccharides.
PubMed:High levan accumulation in transgenic tobacco plants expressing the Gluconacetobacter diazotrophicus levansucrase gene.
PubMed:Cloning and functional characterization of a fructan 1-exohydrolase (1-FEH) in edible burdock (Arctium lappa L.).
PubMed:Characterization of glucan-producing Leuconostoc strains isolated from sourdough.
PubMed:A simple method for the simultaneous decoloration and deproteinization of crude levan extract from Paenibacillus polymyxa EJS-3 by macroporous resin.
PubMed:Expression, purification and use of the soluble domain of Lactobacillus paracasei beta-fructosidase to optimise production of bioethanol from grass fructans.
PubMed:Sucrose: A prospering and sustainable organic raw material.
PubMed:Hydrolytic methods for the quantification of fructose equivalents in herbaceous biomass.
PubMed:Enhanced levan production using chitin-binding domain fused levansucrase immobilized on chitin beads.
PubMed:Two active forms of Zymomonas mobilis levansucrase. An ordered microfibril structure of the enzyme promotes levan polymerization.
PubMed:Analysis of bacterial community during the fermentation of pulque, a traditional Mexican alcoholic beverage, using a polyphasic approach.
PubMed:Rheological characterization of levan polysaccharides from Microbacterium laevaniformans.
PubMed:Functional analysis of the fructooligosaccharide utilization operon in Lactobacillus paracasei 1195.
PubMed:Efficient production of poly-gamma-glutamic acid by Bacillus subtilis ZJU-7.
PubMed:Isolation and characterization of mutants from levan-producing Zymomonas mobilis.
PubMed:selective production and characterization of levan by Bacillus subtilis (Natto) Takahashi.
PubMed:In vitro digestibility and fermentability of levan and its hypocholesterolemic effects in rats.
PubMed:Catalytic activity of zymomonas mobilis extracellular "levan-levansucrase" complex in sucrose medium.
PubMed:Effect of levan's branching structure on antitumor activity.
PubMed:Antitumor activity of levan polysaccharides from selected microorganisms.
PubMed:Effects of several environmental factors on the anti-Listeria monocytogenes activity of an essential oil of Picea excelsa.
PubMed:Strategies and trajectories of coral reef fish larvae optimizing self-recruitment.
PubMed:Influence of nutritional factors on the nature, yield, and composition of exopolysaccharides produced by Gluconacetobacter xylinus I-2281.
PubMed:Levan fructotransferase from Arthrobacter oxydans J17-21 catalyzes the formation of the di-D-fructose dianhydride IV from levan.
PubMed:The Sr1 gene that controls diversity of the anti-inulin antibody response maps to mouse chromosome 14.
PubMed:Investigating the prebiotic and gas-generating effects of selected carbohydrates on the human colonic microflora.
PubMed:In vitro study of prebiotic properties of levan-type exopolysaccharides from Lactobacilli and non-digestible carbohydrates using denaturing gradient gel electrophoresis.
PubMed:Determination of oligofructose, a soluble dietary fiber, by high-temperature capillary gas chromatography.
PubMed:Mutational analysis of avidity and fine specificity of anti-levan antibodies.
PubMed:Biochemical and structural characterization of the glucan and fructan exopolysaccharides synthesized by the lactobacillus reuteri wild-type strain and by mutant strains
PubMed:Identification of gene loci controlling pectate lyase production and soft-rot pathogenicity in Pseudomonas marginalis.
PubMed:Avidity maturation, repertoire shift, and strain differences in antibodies to bacterial levan, a type 2 thymus-independent polysaccharide antigen.
PubMed:Identification of exopolysaccharides produced by fluorescent pseudomonads associated with commercial mushroom (Agaricus bisporus) production.
PubMed:[Severe anaphylactic shock with heart arrest caused by coffee and gum arabic, potentiated by beta-blocking eyedrops].
PubMed:Strain-dependent restricted VH and VL usage by anti-bacterial levan monoclonal antibodies.
PubMed:Pro-melanin-concentrating hormone gene (PMCH) is localized on human chromosome 12q and rat chromosome 7.
PubMed:Microbial levan.
PubMed:Jejunal bypass stimulation of pancreatic growth and cholecystokinin secretion in rats: importance of luminal nutrients.
PubMed:Pseudomonas fluorescens biovar V: its resolution into distinct component groups and the relationship of these groups to other P. fluorescens biovars, to P. putida, and to psychrotrophic pseudomonads associated with food spoilage.
PubMed:Plasma cholecystokinin and pancreatic growth during adaptation to dietary protein.
PubMed:Threshold doses for conditioned avoidance behavior using low dose rate gamma radiations.
PubMed:Post-irradiation avoidance and recovery of preference of saccharin sodium in mice.
 
Notes:
a type 2 thymus-independent polysaccharide antigen. Levan is a substantial component of bacterial plaque produced by certain streptococci and actinomyces, and lipopolysaccharides from Gram-negative bacteria. These bacterial products are B cell mitogens which may have an adjuvant or tolerizing effect on immune responses. (PubMed ID 346320 ) [HMDB]
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