EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

meranzin hydrate
2H-1-benzopyran-2-one, 8-(2,3-dihydroxy-3-methylbutyl)-7-methoxy-

Supplier Sponsors

Name:8-(2,3-dihydroxy-3-methylbutyl)-7-methoxychromen-2-one
CAS Number: 5875-49-0Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J445.062K
MDL:MFCD18974714
XlogP3-AA:1.50 (est)
Molecular Weight:278.30446000
Formula:C15 H18 O5
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 500.50 °C. @ 760.00 mm Hg (est)
Flash Point: 371.00 °F. TCC ( 188.30 °C. ) (est)
logP (o/w): 0.610 (est)
Soluble in:
 water, 1049 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Meranzin hydrate
Coompo
For experimental / research use only.
Meranzin Hydrate from Plants ≥96%
Sigma-Aldrich: Sigma
For experimental / research use only.
Meranzin Hydrate ≥90% (LC/MS-ELSD)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for meranzin hydrate usage levels up to:
 not for fragrance use.
 
Recommendation for meranzin hydrate flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5070783
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
8-(2,3-dihydroxy-3-methylbutyl)-7-methoxychromen-2-one
 
References:
 8-(2,3-dihydroxy-3-methylbutyl)-7-methoxychromen-2-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5070783
Pubchem (sid):47434626
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
2H-1-benzopyran-2-one, 8-(2,3-dihydroxy-3-methylbutyl)-7-methoxy-
8-(2,3-dihydroxy-3-methyl-butyl)-7-methoxy-chromen-2-one
8-(2,3-dihydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one
8-(2,3-dihydroxy-3-methylbutyl)-7-methoxychromen-2-one
 

Articles:

PubMed:Searching the cytochrome p450 enzymes for the metabolism of meranzin hydrate: a prospective antidepressant originating from chaihu-shugan-san.
PubMed:Comparison of Chemical Profiling and Antioxidant Activities of Fruits, Leaves, Branches, and Flowers of Citrus grandis 'Tomentosa'.
PubMed:[Chemical studies on roots of Ficus hirta].
PubMed:Comparison between the pharmacokinetics of meranzin hydrate in a rat model of chronic depression and in controls following the oral administration of Chaihu-Shugan-San.
PubMed:Analysis of major constituents in Fructus aurantii-Magnolia bark decoction by UPLC-PDA.
PubMed:[Determination of the active constituents in aurantii fructus from Jiangxi province at different harvest time by HPLC].
PubMed:Coumarins from the Herb Cnidium monnieri and Chemically Modified Derivatives as Antifoulants against Balanus albicostatus and Bugula neritina Larvae.
PubMed:Meranzin hydrate exhibits anti-depressive and prokinetic-like effects through regulation of the shared α2-adrenoceptor in the brain-gut axis of rats in the forced swimming test.
PubMed:The involvement of AMPA-ERK1/2-BDNF pathway in the mechanism of new antidepressant action of prokinetic meranzin hydrate.
PubMed:Simultaneous quantification of polymethoxylated flavones and coumarins in Fructus aurantii and Fructus aurantii immaturus using HPLC-ESI-MS/MS.
PubMed:Pharmacokinetic study of the prokinetic compounds meranzin hydrate and ferulic acid following oral administration of Chaihu-Shugan-San to patients with functional dyspepsia.
PubMed:Antifibrotic activity of coumarins from Cnidium monnieri fruits in HSC-T6 hepatic stellate cells.
PubMed:Meranzin hydrate induces similar effect to Fructus Aurantii on intestinal motility through activation of H1 histamine receptors.
PubMed:Meranzin hydrate from Muraya paniculata.
PubMed:Two new coumarins from Murraya paniculata.
PubMed:Antibacterial and anticoagulant activities of coumarins isolated from the flowers of Magydaris tomentosa.
PubMed:Antiproliferative effects of isopentenylated coumarins isolated from Phellolophium madagascariense Baker.
PubMed:A new bicoumarin from the leaves and stems of Triphasia trifolia.
PubMed:HPLC comparison of supercritical fluid extraction and solvent extraction of coumarins from the peel of Citrus maxima fruit.
PubMed:[Structure determination of the constituents from Citrus grandis Osbeck].
 
Notes:
None found
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy