EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

trisodium diphosphate
diphosphoric acid, sodium salt (1:3)

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CAS Number: 14691-80-6Picture of molecule3D/inchi
Nikkaji Web:J44.054J
Molecular Weight:243.91920184
Formula:H Na3 O7 P2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:acidity regulators
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 300 Trisodium diphosphate View - notice PDF
JECFA Food Additive: Trisodium Diphosphate
GSFA Codex: Trisodium diphosphate (450(ii))
Physical Properties:
Appearance:white powder (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -3.420 (est)
Soluble in:
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
BOC Sciences
For experimental / research use only.
Diphosphoric acid trisodium salt 95%
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
acidity regulators
Recommendation for trisodium diphosphate usage levels up to:
 not for fragrance use.
Recommendation for trisodium diphosphate flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf

Re-evaluation of phosphoric acid–phosphates – di-, tri- and polyphosphates (E 338–341, E 343, E 450–452) as food additives and the safety of proposed extension of use
View page or View pdf

AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):14691-80-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :161081
National Institute of Allergy and Infectious Diseases:Data
trisodium [hydroxy(oxido)phosphoryl] phosphate
 trisodium [hydroxy(oxido)phosphoryl] phosphate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:14691-80-6
Pubchem (cid):161081
Pubchem (sid):135118436
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 diphosphoric acid, sodium salt (1:3)
 trisodium [hydroxy(oxido)phosphoryl] phosphate
 trisodium hydrogen diphosphate
 trisodium monohydrogen diphosphate
None found
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