EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

tocopherols
methyltocols

Supplier Sponsors

CAS Number: 1406-66-2Picture of molecule3D/inchi
FDA UNII: R0ZB2556P8
XlogP3-AA:10.30 (est)
Molecular Weight:416.68896000
Formula:C28 H48 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:antioxidants and preservatives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
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Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1890 Tocopherols View - review
FDA Mainterm (SATF):1406-66-2 ; TOCOPHEROLS
FDA Regulation:
FDA PART 101 -- FOOD LABELING
Subpart A--General Provisions
Sec. 101.9 Nutrition labeling of food.


FDA PART 107 -- INFANT FORMULA
Subpart D--Nutrient Requirements
Sec. 107.100 Nutrient specifications.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart D--Chemical Preservatives
Sec. 182.3890 Tocopherols.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart I--Nutrients
Sec. 182.8890 Tocopherols.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart I--Nutrients
Sec. 182.8892 [b.alpha]-Tocopherol acetate.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1890 [b.alpha]-Tocopherols.
 
Physical Properties:
Assay: 92.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 518.00 to 519.00 °C. @ 760.00 mm Hg (est)
Flash Point: 403.00 °F. TCC ( 206.00 °C. ) (est)
logP (o/w): 10.724 (est)
Soluble in:
 water, 1.069e-006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antioxidants
fragrance
skin conditioning
 
Suppliers:
ADM
NOVATOL 3-50SD
Flavor: characteristic
NOVATOL 3-50 is a tan-white granular powder having little or no odor or taste. NOVATOL 3-50 may oxidize upon exposure to air and light and protection from heat, from transition metals and from alkali is recommended. NOVATOL 3-50 is a concentrated form of natural mixed tocopherols derived from edible vegetable oils. This unique product is produced by spray drying NOVATOL 3-50 granules with gelatin, resulting in a free-flowing, granular powder. NOVATOL 3-50 is an essential nutrient and dietary supplement widely used in tableting. It is especially recommended in multivitamins and chewable tablets. It has minimal interactions with other ingredients commonly used in multivitamin products.
ADM
NOVATOL 4-80
BOC Sciences
For experimental / research use only.
Tocopherols
Columbus Vegetable Oils
Tocopherol
ECSA Chemicals
NATURAL TOCOPHEROL
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
Farbest-Tallman Foods
Natural Mixed Tocopherols 70%
Flavor: bland
This product can be used in food products as a natural antioxidant and also in soft gel capsules as a natural Vitamin E source.
Kraft Chemical
Tocopherol - Mixed
Sigma-Aldrich
Tocopherols, mixed, FCC, FG
Certified Food Grade Products
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
antioxidants and preservatives
Recommendation for tocopherols usage levels up to:
 not for fragrance use.
 
Recommendation for tocopherols flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Inability to assess the safety of beta-, gamma- and delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl-tocotrienol added for nutritional purposes as sources of beta-, gamma- and delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl- tocotrienol in food supplements and the bioavailability of beta-, gamma-, delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl-tocotrienol from the different sources, based on the supporting dossiers [1]
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :14986
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-ol
Chemidplus:0001406662
EPA/NOAA CAMEO:hazardous materials
 
References:
 2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-ol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):14986
Pubchem (sid):134981326
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB01492
FooDB:FDB010395
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
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 not found in nature
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Synonyms:
 methyltocols
2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-ol
 
 
Notes:
Tocopherols are a class of chemical compounds of which many have vitamin E activity. It is a series of organic compounds consisting of various methylated phenols. [Wikipedia]
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