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sodium stearyl fumarate
sodium (E)-4-octadecoxy-4-oxobut-2-enoate

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Name:sodium (E)-4-octadecoxy-4-oxobut-2-enoate
CAS Number: 4070-80-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:223-781-1
Nikkaji Web:J217.877J
Molecular Weight:390.53939928
Formula:C22 H39 Na O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:dough conditioners, conditioning agents, stabilizing agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
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Pubchem Patents:Search
FDA Regulation:
Subpart I--Multipurpose Additives
Sec. 172.826 Sodium stearyl fumarate.
Physical Properties:
Food Chemicals Codex Listed: No
Boiling Point: 483.40 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000000 mmHg @ 25.00 °C. (est)
Flash Point: 308.00 °F. TCC ( 153.50 °C. ) (est)
logP (o/w): 8.789 (est)
Soluble in:
 water, 0.0001422 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: bulking agents
Indis NV
For experimental / research use only.
Sodium Stearyl Fumarate
Santa Cruz Biotechnology
For experimental / research use only.
Sodium Stearyl Fumarate
For experimental / research use only.
Sodium Stearyl Fumarate
European Pharmacopoeia (EP) Reference Standard
For experimental / research use only.
Sodium Stearyl Fumarate >98.0%(T)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
dough conditioners, conditioning agents, stabilizing agents
Recommendation for sodium stearyl fumarate usage levels up to:
 not for fragrance use.
Recommendation for sodium stearyl fumarate flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23665634
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
sodium (E)-4-octadecoxy-4-oxobut-2-enoate
 sodium (E)-4-octadecoxy-4-oxobut-2-enoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):23665634
Pubchem (sid):135017729
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
KEGG (GenomeNet):D05876
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2917.19.7050
FDA Listing of Food Additive Status:View
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 sodium (E)-4-octadecoxy-4-oxobut-2-enoate
 sodium monooctadecyl fumarate
 sodium monostearyl fumarate
 sodium octadecyl fumarate


PubMed:Influence of coating material on the flowability and dissolution of dry-coated fine ibuprofen powders.
PubMed:Investigating critical effects of variegated lubricants, glidants and hydrophilic additives on lag time of press coated ethylcellulose tablets.
PubMed:[Theoretical modeling and experimental research on direct compaction characteristics of multi-component pharmaceutical powders based on the Kawakita equation].
PubMed:Influence of emulsifier structure on lipid bioaccessibility in oil-water nanoemulsions.
PubMed:[Preparation and application on compound excipient of sodium stearyl fumarate and plasdone S-630].
PubMed:Formulating weakly basic HCl salts: relative ability of common excipients to induce disproportionation and the unique deleterious effects of magnesium stearate.
PubMed:Development of novel bepotastine salicylate salt bioequivalent to the commercial bepotastine besilate in beagle dogs.
PubMed:Measurement of flowability of lubricated powders by the vibrating tube method.
PubMed:[Selected adjuvants as carriers of a dry extract of common ivy (Hedera helix L.)].
PubMed:[A new water-soluble lubricant of tablets-L-leucine combined with PEG6000].
PubMed:Preparation and physicochemical evaluation of a new tacrolimus tablet formulation for sublingual administration.
PubMed:Energy evaluation of the compaction process of directly compressible isomalt.
PubMed:Formulation and In-Vitro Evaluation of Ocular Ciprofloxacin-Containing Minitablets Prepared with Different Combinations of Carbopol 974P and Various Cellulose Derivatives.
PubMed:[Tableting technology of a dry extract from Solidago virgaurea L. with the use of silicified microcrystalline cellulose (Prosolv) and other selected auxiliary substances].
PubMed:Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia.
PubMed:Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol.
PubMed:A study of the properties of tablets from the mixtures of directly compressible starch and directly compressible lactitol.
PubMed:A study of the properties of compacts from silicified microcrystalline celluloses.
PubMed:Nanoscopic friction behavior of pharmaceutical materials.
PubMed:Packed column supercritical fluid chromatography of sodium stearyl fumarate aqueous suspension.
PubMed:Intrinsic adhesion force of lubricants to steel surface.
PubMed:Potential application of silicified microcrystalline cellulose in direct-fill formulations for automatic capsule-filling machines.
PubMed:Comparative evaluation of co-processed lactose and microcrystalline cellulose with their physical mixtures in the formulation of folic acid tablets.
PubMed:[The effect of two lubricants (magnesium stearate and pruv) in the formation of tablets of four anti-ulcer agents/ by means of direct compression].
PubMed:Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution.
PubMed:The absorption and metabolism of orally administered tritium labeled sodium stearyl fumarate in the rat and dog.
Used as a food additive [EAFUS]
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