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potassium saccharin
1,2-benzisothiazol-3(2H)-one, 1,1-dioxide, potassium salt (1:1)

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Name:potassium 1,1-dioxo-1,2-benzothiazol-2-id-3-one
CAS Number: 10332-51-1Picture of molecule3D/inchi
FDA UNII:K2BEG3J28N
Molecular Weight:221.27678000
Formula:C7 H4 K N O3 S
NMR Predictor:Predict (works with chrome or firefox)
Category:sweeteners, flavor enhancers
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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NCBI:Search
JECFA Food Additive: Potassium Saccharin
GSFA Codex: Potassium saccharin (954(iii))
DG SANTE Food Additives:potassium saccharin
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 226.00 to 230.00 °C. @ 760.00 mm Hg
Soluble in:
 water, 1.725e+004 mg/L @ 25 °C (est)
 alcohol, very slightly
Insoluble in:
 alcohol
 
Organoleptic Properties:
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
1,2-Benzisothiazol-3(2H)-one,1,1-dioxide, potassium salt (1:1)
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
sweeteners, flavor enhancers
Recommendation for potassium saccharin usage levels up to:
 not for fragrance use.
 
Recommendation for potassium saccharin flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Outcome of the public consultation on a draft protocol for assessing exposure to sweeteners as part of their safety assessment under the food additives re-evaluation programme
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):10332-51-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :12193862
National Institute of Allergy and Infectious Diseases:Data
potassium 1,1-dioxo-1,2-benzothiazol-2-id-3-one
Chemidplus:0010332511
 
References:
 potassium 1,1-dioxo-1,2-benzothiazol-2-id-3-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):12193862
Pubchem (sid):135023108
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
1,2-benzisothiazol-3(2H)-one, 1,1-dioxide, potassium salt (1:1)
 potassium 1,1-dioxo-1,2-benzothiazol-2-id-3-one
 potassium saccharate
 saccharin potassium salt
 

Articles:

PubMed:Two Cu21 clusters with pseudo-D3 symmetry derived from the D-saccharate pentaanion, C6H5O8(5-).
PubMed:In vitro cytotoxicity of the sodium, potassium and calcium salts of saccharin, sodium ascorbate, sodium citrate and sodium chloride.
PubMed:The effect of various saccharin forms on gastro-intestinal tract, urine and bladder of male rats.
PubMed:The effect of different salts of saccharin on the rat urinary bladder.
PubMed:Inhibition of cinchophen ulcer in chicks with boiled potassium hydrogen saccharate.
PubMed:Inhibition of uterine beta-glucuronidase activity in the rat by local application of potassium hydrogen saccharate.
PubMed:Acute and chronic toxicity of potassium acid saccharate.
PubMed:Effect of feeding potassium acid saccharate in the diet of rats for successive generations.
 
Notes:
None found
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