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sugar invert
saccharide hydrolysate

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Flavor Demo Formulas
CAS Number: 8013-17-0Picture of molecule3D/inchi
Molecular Weight:360.31368000
Formula:C12 H24 O12
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:multipurpose additives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Pubchem Patents:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1859 Invert Sugar View - review
FDA Mainterm (SATF):8013-17-0 ; INVERT SUGAR
FDA Regulation:
Subpart B--Requirements for Specific Standardized Milk and Cream
Sec. 131.112 Cultured milk.

Subpart B--Requirements for Specific Standardized Milk and Cream
Sec. 131.170 Eggnog.

Subpart B--Requirements for Specific Standardized Milk and Cream
Sec. 131.200 Yogurt.

Subpart B--Requirements for Specific Standardized Milk and Cream
Sec. 131.203 Lowfat yogurt.

Subpart B--Requirements for Specific Standardized Milk and Cream
Sec. 131.206 Nonfat yogurt.

Subpart B--Requirements for Specific Standardized Canned Fruit Juices and Beverages
Sec. 146.140 Pasteurized orange juice.

Subpart B--Requirements for Specific Standardized Canned Fruit Juices and Beverages
Sec. 146.141 Canned orange juice.

Subpart B--Requirements for Specific Standardized Canned Fruit Juices and Beverages
Sec. 146.145 Orange juice from concentrate.

Subpart B--Requirements for Specific Standardized Canned Fruit Juices and Beverages
Sec. 146.146 Frozen concentrated orange juice.

Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.175 Vanilla extract.

Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1859 Invert sugar.

Subpart A--Foods
Sec. 73.85 Caramel.
Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Flavor Type: sweet
sweet sugar
Taste Description: sweet
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: humectants
Domino Foods
FreshVert® and Nulomoline® Invert Sugars
Flavor: sweet
Standardized inverts made from pure cane sugar by a process that converts sucrose into a combination of fructose and dextrose sugars, resulting in a characteristically unique sweetener system. These sugars have significantly different characteristics than sucrose, corn syrup combinations, or other sugars, and offer a lighter flavor, increased moisture retention in fresh baked goods, improved crust color, solubility, and enhanced shelf life. FreshVert®; Liquid and Nulomoline®; #7 are liquid forms, FreshVert®; Creamy and Nulomoline®; Congealed are high-solids forms, and Nulomoline®; #11 is a partial-invert liquid form.
Domino Foods
Invert Sugar
Flavor: sweet
These exceptional sweeteners produce excellent results in bakery and confectionary applications. Our invert sugars boost the color and flavor, preserve freshness and decrease graining for a desired uniform appearance. Invert sugar is a natural humectant and provides solubility, resistance to crystallization, viscosity, and sweetness and enhances the quality of the end product.
Domino Foods
Liquicane® Sugars
Flavor: sweet
Convenient, easy to handle, and available in several formats: the total-invert Liquicane®; Type 90, a high-solids medium-invert Type-50, and Type-0, which crystallizes at very low temperatures Its applications include soft drinks, yogurt, ice cream, and other sweetened beverages.
ECSA Chemicals
Horner International
Sugar Invert
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
multipurpose additives
Recommendation for sugar invert usage levels up to:
 not for fragrance use.
Recommendation for sugar invert flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Outcome of the public consultation on a draft protocol for the Scientific Opinion on dietary sugars
View page or View pdf

Protocol for the scientific opinion on the Tolerable Upper Intake Level of dietary sugars
View page or View pdf

AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8013-17-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :21924868
National Institute of Allergy and Infectious Diseases:Data
2,3,4,5,6-pentahydroxyhexanal; 1,3,4,5,6-pentahydroxyhexan-2-one
 2,3,4,5,6-pentahydroxyhexanal; 1,3,4,5,6-pentahydroxyhexan-2-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):21924868
Pubchem (sid):135264383
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 elder black elder plant
Search Trop Picture
 fig fruit
Search Trop Picture
 not found in nature
2,3,4,5,6-pentahydroxyhexanal; 1,3,4,5,6-pentahydroxyhexan-2-one
 saccharide hydrolysate
invert sugar
 sugar invert


PubMed:Complete sucrose hydrolysis by heat-killed recombinant Pichia pastoris cells entrapped in calcium alginate.
PubMed:Process optimization for the manufacture of angoori petha.
PubMed:Effects of drought stress on biomass and carbohydrate contents of two sweet sorghum cultivars.
PubMed:Biological activities and some physicochemical properties of sunflower honeys collected from the Thrace region of Turkey.
PubMed:Immobilized Sclerotinia sclerotiorum invertase to produce invert sugar syrup from industrial beet molasses by-product.
PubMed:A thermostable exo-β-fructosidase immobilised through rational design.
PubMed:Highly efficient method towards in situ immobilization of invertase using cryogelation.
PubMed:One-step magnetic modification of yeast cells by microwave-synthesized iron oxide microparticles.
PubMed:Cassava starch-based films plasticized with sucrose and inverted sugar and reinforced with cellulose nanocrystals.
PubMed:Chemical constituents and free radical scavenging activity of corn pollen collected from Apis mellifera hives compared to floral corn pollen at Nan, Thailand.
PubMed:Nano-tubular cellulose for bioprocess technology development.
PubMed:Scientific assessment of the use of sugars as cigarette tobacco ingredients: a review of published and other publicly available studies.
PubMed:Rapid honey characterization and botanical classification by an electronic tongue.
PubMed:Effects of nitrogen treatments and harvesting stages on the aconitic acid, invert sugar and fiber in sweet sorghum cultivars.
PubMed:A comprehensive evaluation of the toxicology of cigarette ingredients: carbohydrates and natural products.
PubMed:Biochemical properties of red currant varieties in relation to storage.
PubMed:Immobilization of cell wall invertase modified with glutaraldehyde for continuous production of invert sugar.
PubMed:Studies on dehydration of figs using different sugar syrup treatments.
PubMed:Determination of some chemical parameters and antimicrobial activity of traditional food: mesir paste.
PubMed:Honey bee foraging preferences, effects of sugars, and fruit fly toxic bait components.
PubMed:Nutritional composition, microbiological and sensory properties of dried melon: a traditional Turkmen product.
PubMed:Inter-relationship between growth analysis and carbohydrate contents of sweet sorghum cultivars and lines.
PubMed:Immobilization of recombinant invertase (re-INVB) from Zymomonas mobilis on D-sorbitol cinnamic ester for production of invert sugar.
PubMed:Effects of irrigation water qualities on biomass and sugar contents of sugar beet and sweet sorghum cultivars.
PubMed:Alkaline degradation of invert sugar from molasses.
PubMed:Isolation and identification of select oligosaccharides from commercially produced total invert sugar with a proposed mechanism for their formation.
PubMed:Safety assessment of high fructose corn syrup (HFCS) as an ingredient added to cigarette tobacco.
PubMed:Coalescence of protein-stabilized bubbles undergoing expansion at a simultaneously expanding planar air-water interface.
PubMed:Dietary factors and dental caries.
PubMed:Acrylamide: update on selected research activities conducted by the European food and drink industry.
PubMed:The three-dimensional structure of invertase (beta-fructosidase) from Thermotoga maritima reveals a bimodular arrangement and an evolutionary relationship between retaining and inverting glycosidases.
PubMed:Dietary factors in the prevention of dental caries: a systematic review.
PubMed:Toxicological evaluation of honey as an ingredient added to cigarette tobacco.
PubMed:Specific screening for color precursors and colorants in beet and cane sugar liquors in relation to model colorants using spectrofluorometry evaluated by HPLC and multiway data analysis.
PubMed:Effects of intrapartum administration of invert sugar and D5LR on neonatal blood glucose levels.
PubMed:Capillary gas chromatographic detection of invert sugar in heated, adulterated, and adulterated and heated apple juice concentrates employing the equilibrium method.
PubMed:Stability of captopril in invert sugar solution.
PubMed:Regulation of acetic acid production by homo- and heterofermentative lactobacilli in whole-wheat sour-doughs.
PubMed:Determination of honey authenticity by anion-exchange liquid chromatography.
PubMed:Microbial counts and invert sugars in juice extracts from stored tubers of Cyperus esculentus Linn. (earth almond).
PubMed:Progression of approximal caries in primary molars and the effect of Duraphat treatment.
PubMed:Application of polystyrene-bound invertase to continuous sucrose hydrolysis on pilot scale.
PubMed:[Effect of carbohydrate structure on glucose utilization and biosynthesis of lipids, proteins and glucagon in rats].
PubMed:Detection of orange juice adulteration with beet medium invert sugar using anion-exchange liquid chromatography with pulsed amperometric detection.
PubMed:Effect of partial substitution of invert sugar for sucrose in combination with Duraphat treatment on caries development in preschool children: the Malmö Study.
PubMed:Oral sugar clearance in children compared with adults.
PubMed:[Features of the effects of disaccharide structure of saccharose on kinetic parameters of hepatic lipid synthesis from glucose (mechanism of disaccharide effect)].
PubMed:[Effect of sucrose on lipid metabolism in rats: confirmation of the disaccharide effect].
PubMed:Varisol in the treatment of telangiectasia.
PubMed:The disaccharide effect of sucrose feeding on excretion of intravenously injected [1,2-3H]aldosterone and conjugated glucuronic acid in normotensive rats.
PubMed:[Sugar in the diet].
PubMed:[Amino acid administration in acute, compensated renal failure in the post-traumatic phase].
PubMed:Isolation and characterization of bacterial strains with inulinase activity.
PubMed:Stability of sulbactam/ampicillin in diluents for parenteral administration.
PubMed:Intake and gastric emptying of mono- versus disaccharides by rats.
PubMed:Absence of a generalized disaccharide effect in adult female rats.
PubMed:[Blood viscosity changes due to infusions in childhood].
PubMed:Enzymatic hydrolysis and fermentation of corn for fuel alcohol.
PubMed:Microbiological aspects of some caloric sugar substitutes.
PubMed:The effects of different concentrations of sucrose, fructose, and glucose on pH changes by Streptococcus mitior in an artificial mouth.
PubMed:The disaccharide effect of sucrose feeding on glucuronide excretion and bile concentration of injected phenolphthalein in guinea pigs.
PubMed:Which carbohydrates should we recommend for intravenous nutrition?
PubMed:Microbiological aspects of heat sterilization of medicines. II. A method for the determination of the effectiveness of a sterilization process using the bioburden and the bioburdens heat resistance.
PubMed:Metabolic effects of glucose compared with invertose and a mixture of fructose, glucose and xylitol before and after moderate surgical trauma.
PubMed:Application of immobilized invertase to continuous hydrolysis of concentrated sucrose solutions.
PubMed:Prolonged red cell survival following in vitro treatment with potassium cyanate. A study in patients undergoing open-heart surgery.
PubMed:Treatment of bovine ketosis with invert sugar, glucocorticoids, and propylene glycol.
PubMed:Improved red cell survival in patients with chronic subclinical haemolysis due to artificial heart valve. Observations after in vitro treatment of the cells with potassium cyanate.
PubMed:Blood insulin, glucose, fructose and gastric inhibitory polypeptide levels in carbohydrate-sensitive and normal men given a sucrose or invert sugar tolerance test.
PubMed:[Animal experiment studies and oral plaque pH measurements on the cariogenicity of invert sugar in drinks].
PubMed:[Effects of sucrose and invert sugar on the levels of plasma lipids, plasma ApoA concentrations and chemical composition of high density lipoprotein subfractions in healthy young males (author's transl)].
PubMed:[Parenteral nutrition in gastro-intestinal surgery (author's transl)].
PubMed:Effect of invert sugar on accumulation of Streptococcus mutans E49 on the teeth of rats.
PubMed:Cariogenicity of invert sugar in long-term rat experiments.
PubMed:Metabolic responses of Zucker fatty and lean rats fed carbohydrate diets ad libitum or in meals.
PubMed:[Discovery of fructose intolerance in a case of acute liver failure in a 16-month-old child].
PubMed:Effects of pyridoxine, phytate and invert sugar on plaque composition and caries activity in the monkey (Macaca fascicularis).
PubMed:Determination of endotoxins in sugar with the Limulus test.
PubMed:Stability of antibiotics and amino acids in two synthetic L-amino acid solutions commonly used for total parenteral nutrition in children.
PubMed:[Use of invert sugar, fructose and sorbitol and on their effect on various plasma constituents after intravenous infusion in the dog].
PubMed:[Behavior of various blood constituents (glucose, fructose, insulin, lactate, pyruvate, free fatty acids, inorganic phosphate) and the half-life of monosaccharides in plasma after i.v infusion of glucose, fructose, galactose and invert sugar solutions in ruminants. 3. Studies in sheep].
PubMed:[Behavior of various blood constituents (glucose, fructose, insulin, lactate, pyruvate, free fatty acids, inorganic phosphate) and half-life of monosaccharides in the plasma after i.v. infusion of glucose, fructose, galactose and invert sugar solutions in ruminants. 2. Studies in cattle].
PubMed:[Behavior of various blood constituents (glucose, fructose, insulin, lactate, pyruvate, free fatty acids, inorganic phosphate) and half-life of monosaccharides in the plasma after i.v. infusion of glucose, fructose, galactose and invert sugar solutions in ruminants. 1. Studies in calves and heifers].
PubMed:Polysaccharide contaminants in ultra pure grade sucrose with relation to anaphylactoid reactions in the clinical use of invert sugar solutions. II. Studies on the chemical structure of two native dextrans.
PubMed:Glucans and dextrans in rats and man.
PubMed:Biochemical effects of and bacteriological response to sugar substitutes in the oral environment.
PubMed:The effect of pyridoxine, phytate and invert sugar on production of plaque acids in situ in the monkey (M. fascicularis).
PubMed:[Volkmann's contracture after extravascular infusion of hypertonic invertose].
PubMed:[Studies on the effects of intravenous administration of glucose, fructose, invertose and sorbitol on various blood constituents of blood plasma (monosaccharides, insulin, lactate, pyruvate and free fatty acids as well as glutamate-oxaloacetate transaminase) in the horse].
PubMed:Maximal infusion rate of invertose in the postoperative period.
PubMed:Ornithine decarboxylase activity in tooth surface plaque from monkeys (Macaca fascicularis) fed pyridoxine, phytate and invert sugar.
PubMed:Infusion thrombophlebitis in a surgical department.
PubMed:Hemolysis of erythrocytes by primary pharmacologic agents, part 2: influence of the vehicle.
PubMed:Observations on hexachlorophene-induced paralysis in the cat and its antagonism by hypertonic urea.
PubMed:Changes in Resident Bacteria, pH, Sucrose, and Invert Sugar Levels in Sugarbeet Roots During Storage.
PubMed:Tissue toxicity of intravenous solutions. A phlebographic and experimental study.
PubMed:Blood-aqueous barrier can be circumvented by lowering intraocular pressure.
PubMed:Anaphylactoid reactions in connection with infusion of invert sugar solutions are due to macromolecular contaminants.
PubMed:Polysaccharide contaminants in ultra pure grade sucrose with relation to anaphylactoid reactions in clinical use of invert sugar solutions.
PubMed:Sugar polymers in rats and man.
PubMed:[Technology of the production and clinical use of infusible solution of invert sugar].
PubMed:Demonstration of a specific metabolic effect of dietary disaccharides in the rat.
PubMed:Microflora and invert sugars in juice from healthy tissue of stored sugarbeets.
PubMed:Treatment of sickle cell crisis with urea in invert sugar. A controlled trial. Cooperative urea trials group.
PubMed:Effect of restricting oral intake to invert sugar or casein on the microbiology of plaque in Macaca fascicularis (irus).
PubMed:[40 percent invert sugar solution for parenteral feeding].
PubMed:[Possibility of using chemoluminescent analysis for establishing adulteration of flower honey with honeydew and invert sugar].
PubMed:[Kinetics of crystallization of D-glucose hydrate from high-percentage invert sugar solution].
PubMed:[Quantitative analysis of drug preparations using simple methods. 4. Determination of the content of invertose solution in Oculentum saccharosi inversi SR].
PubMed:Experience with urea in invert sugar for the treatment of cerebral malaria.
PubMed:Effect of intravenous urea in invert sugar on heme catabolism in sickle-cell anemia.
PubMed:Sickling reversed and blocked by urea in invert sugar.
PubMed:Use of Torulopsis utilis and invert sugar in Streptomycin fermentation.
PubMed:[Determination of potassium d-arabinose in a mixture with invert sugar].
PubMed:[The preparation of invert sugar solutions].
PubMed:[The determination of the ammonia content in concentrated solutions of urea and invert sugar].
PubMed:Pulmonary aspiration of gastric acid: Mendelson's syndrome. Successful treatment with lyophilized urea and ten per cent invert sugar.
PubMed:The effect of urea and invert sugar (Urevert) on cerebral damage occurring after cardiac arrest.
PubMed:[Preparation of invert sugar infusion solution under field conditions].
PubMed:Head injuries in infants and young children.
PubMed:Importance of caloric intake during renal failure.
PubMed:Use of glucose, invert sugar and fructose for parenteral feeding of children.
PubMed:[Treatment of circulatory disturbances by nucleoside extracts and invert sugar].
PubMed:[Photometric determination of g-strophantin with aqueous solutions of invert sugar after shaking with ethyl alcohol].
PubMed:Comparative utilization of intravenous fructose and invert sugar.
PubMed:[Varico-calorose in percutaneous therapeutic obliteration of varicose veins].
PubMed:Protein nutrition in surgical patients. II. A comparison of the nitrogen-sparing action of glucose, invert sugar, and fructose.
PubMed:The utilization of intravenously administered glucose, invert sugar, and fructose in cattle.
PubMed:Rate of glycogenesis in the liver of the rat after parenteral administration of glucose, fructose and invert sugar.
PubMed:Hyperpotassemia and hyperglycemia; treatment with insulin and invert sugar.
PubMed:[Blood and invert sugar; an observation].
PubMed:Utilization of glucose, fructose and invert sugar; comparison in diseases of the liver and pancreas.
PubMed:Invert sugar in parenteral nutrition.
PubMed:[Preparation of invert sugar solutions for parenteral administration].
PubMed:[Effects of prophylactic treatment with invert-sugar on disorders of carbohydrate metabolism by surgery].
PubMed:[The significance of invert sugar in infant nutrition].
PubMed:Utilization of intravenously injected fructose and invert sugar in normal human subjects.
PubMed:Some observations on the use of fructose and invert sugar in infants.
PubMed:The excretion of sugars after the intravenous administration of invert sugar.
PubMed:[Significance of invert sugar for infant nutrition].
PubMed:FRUCTOSE and invert sugar versus glucose.
PubMed:Invert sugar in insulin coma therapy.
PubMed:Comparative observations regarding utilization and excretion of infused glucose, fructose, and invert sugar, respectively.
PubMed:The utilization of dextrose, levulose, and invert sugar by normal and surgical patients. Part II.
PubMed:[Preparation of sterile solutions of invert sugar].
PubMed:The utilization of dextrose, levulose, and invert sugar by normal and surgical patients.
PubMed:[Change of dextrose and invert sugar by heating (sterilization)].
PubMed:[Comparative experimental studies on increase of carbohydrate content in heart muscle after peroral glucose, invert sugar and levulose administration].
PubMed:[Lipid metabolism in carbon tetrachloride poisoned dogs and the effect of methionine, inositol and invert sugar].
PubMed:The utilization of invert sugar and glucose following intravenous administration to postoperative patients.
PubMed:A comparison of the response of normal subjects to the intravenous administration of 5% glucose and 10% invert sugar.
PubMed:NEW and nonofficial remedies: invert sugar.
PubMed:Comparative utilization of intravenous invert sugar and glucose.
PubMed:[Comparative investigations on the effects of honey and invert sugar on the blood sugar].
PubMed:Some considerations regarding invert sugar and dextrose.
PubMed:[Lipotropic action of vitamine E and cystine, methionine, inosit and invert sugar on the rat poisoned with carbon tetrachloride].
PubMed:PARENTERAL alimentation with invert sugar.
PubMed:The metabolic fate of invert sugar. Part II. Glycogen formation in liver and muscle.
PubMed:Use of invert sugar solutions for parenteral feeding of surgical patients.
PubMed:[Effect of invert sugar in dermatoses, allergoses and capillary toxicoses].
PubMed:The metabolic fate of invert sugar. Part I. Absorption, excretion and the effect of insulin on the utilization of sugar.
PubMed:Comparative utilization of invert sugar and dextrose in nondiabetic human beins.
PubMed:Tolerance of human beings to intravenous infusions of fifteen per cent invert sugar.
PubMed:Rapid infusions of invert sugar.
PubMed:Parenteral therapy with invert sugar.
PubMed:Study of Ofner's method for the determination of invert sugar.
PubMed:The mechanism of selective fermentation of d-fructose from invert sugar by sauternes yeast.
PubMed:The mechanism of selective fermentation of d-fructose from invert sugar by Sauternes yeast.
mixture of approx 50% dextrose & 50% levulose obtained by acid hydrolysis of cane sugar. Inverted or invert sugar syrup is a mixture of glucose and fructose; it is obtained by splitting sucrose into these two components. Compared with its precursor, sucrose, inverted sugar is sweeter and its products tend to remain more moist and are less prone to crystallisation. Inverted sugar is therefore valued by bakers, who refer to the syrup as trimoline or invert syrup.
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