EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

calcium malate
calcium DL-malate

Supplier Sponsors

Name:calcium 2-hydroxybutanedioate
CAS Number: 17482-42-7Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:241-498-1
FDA UNII: Search
Nikkaji Web:J248.901E
Molecular Weight:172.14988000
Formula:C4 H4 Ca O5
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:buffering agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
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Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
EU SANCO Calcium malates View - review
JECFA Food Additive: Calcium DL-malate
GSFA Codex: Calcium malate, (DL-) (352(ii))
DG SANTE Food Additives:calcium malate
Physical Properties:
Appearance:white powder (est)
Assay: 97.50 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 305.00 to 307.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.000072 mmHg @ 25.00 °C. (est)
Flash Point: 308.00 °F. TCC ( 153.33 °C. )
logP (o/w): -1.261 (est)
Soluble in:
 water, slightly
Insoluble in:
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
American Elements
Calcium Malate 99%
Odor: characteristic
Use: Calcium Malate is one of numerous organo-metallic compounds sold by American Elements under the tradename AE Organo-Metallics™ for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications. Calcium Malate is generally immediately available in most volumes, including bulk quantities. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Calcium Malate Dihydrate
BOC Sciences
For experimental / research use only.
Calcium Malate: Butanedioicacid, hydroxy,calcium salt 95%
Jost Chemical
Calcium Malate Purified Granular
Jost Chemical
Calcium Malate Purified Powder
Qingdao Dacon Trading
Calcium Malate
Sabinsa Corporation
Calcium Malate
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
buffering agents
Recommendation for calcium malate usage levels up to:
 not for fragrance use.
Recommendation for calcium malate flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Calcium, Magnesium and Zinc Malate added for nutritional purposes to food supplements as sources for Calcium, Magnesium and Zinc and to Calcium Malate added for nutritional purposes to foods for particular nutritional uses and foods intended for the general population as source for Calcium
View page or View pdf
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :167659
National Institute of Allergy and Infectious Diseases:Data
calcium 2-hydroxybutanedioate
 calcium 2-hydroxybutanedioate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):167659
Pubchem (sid):135122692
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 calcium 2-hydroxybutanedioate
 calcium DL-malate
 calcium dextro,laevo-malate
dextro,laevo-monocalcium malate
2-hydroxybutanedioic acid monocalcium salt


PubMed:Microbial biosynthesis and secretion of l-malic acid and its applications.
PubMed:Calcium malate overproduction by Penicillium viticola 152 using the medium containing corn steep liquor.
PubMed:Overproduction of poly(β-malic acid) (PMA) from glucose by a novel Aureobasidium sp. P6 strain isolated from mangrove system.
PubMed:High-level production of calcium malate from glucose by Penicillium sclerotiorum K302.
PubMed:Assessment the levels of tartrate-resistant acid phosphatase (TRAP) on mice fed with eggshell calcium citrate malate.
PubMed:Optimized extraction of calcium malate from eggshell treated by PEF and an absorption assessment in vitro.
PubMed:[Determination of calcium in calcium citrate and calcium malate by X-ray fluorescence spectrum].
PubMed:Effects of malate on diet digestibility, microbial protein synthesis, plasma metabolites, and performance of growing lambs fed a high-concentrate diet.
PubMed:Calcium (hydrogen-1-malate) hexahydrate on Echeveria gibbiflora leaves and its effect on sperm cells.
PubMed:Effect of the addition of malate on in vitro rumen fermentation of cereal grains.
PubMed:Absorption of calcium fumarate salts is equivalent to other calcium salts when measured in the rat model.
PubMed:[Study on the optimal conditions in simultaneous reaction and separation for L-malic acid production].
PubMed:[Azomonas agilis in the surface water of the environs of Buenos Aires].
None found
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