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asparaginase from aspergillus niger expressed in aspergillus niger
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Category:enzyme preparations and microorganisms
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Notes: nci: an enzyme isolated from the bacterium escherichia coli or the bacterium erwinia carotovora with antileukemic activity. asparaginase hydrolyzes l-asparagine to l-aspartic acid and ammonia in leukemic cells, resulting in the depletion of asparagine, inhibition of protein synthesis, cell cycle arrest in the g1 phase, and apoptosis in susceptible leukemic cell populations. see more at nci
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