EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

lactoyl tyramine
2-hydroxy-N-[2-(4-hydroxyphenyl)ethyl]propanamide

Supplier Sponsors

CAS Number: 781674-18-8Picture of molecule3D/inchi
FDA UNII: DU72SR0368
XlogP3-AA:0.90 (est)
Molecular Weight:209.24515000
Formula:C11 H15 N O3
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:flavor enhancers
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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NCBI:Search
JECFA Food Flavoring:2007 (+/-)-N-lactoyl tyramine
DG SANTE Food Flavourings:16.107 2-hydroxy-N-[2-(4-hydroxyphenyl)ethyl]propanamide
FEMA Number:4550 (+/-)-N-lactoyl tyramine
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):781674-18-8 ; (+/-)-N-LACTOYLTYRAMINE
 
Physical Properties:
Appearance:brown viscous liquid (est)
Assay: 90.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.19800 to 1.20200 @ 25.00 °C.
Pounds per Gallon - (est).: 9.969 to 10.002
Refractive Index:1.57000 to 1.57600 @ 20.00 °C.
Melting Point: 87.00 to 88.00 °C. @ 760.00 mm Hg
Boiling Point: 87.00 to 88.00 °C. @ 0.00 mm Hg
Soluble in:
 water, 3133 mg/L @ 25 °C (est)
 alcohol, slightly
Insoluble in:
 pentane
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Parchem
lactoyl tyramine
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor enhancers
Recommendation for lactoyl tyramine usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 12.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 17000 (μg/person/day)
Threshold of Concern:90 (μg/person/day)
Structure Class: III
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: 100.00000300.00000
confectionery froastings: --
egg products: --
fats / oils: 100.00000300.00000
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: 100.00000300.00000
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: 100.00000300.00000
soft candy: --
soups: 100.00000300.00000
sugar substitutes: --
sweet sauces: --
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): --
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 100.00000300.00000
Edible ices, including sherbet and sorbet (03.0): --
Processed fruit (04.1): --
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): --
Chewing gum (05.3): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): --
Bakery wares (07.0): --
Meat and meat products, including poultry and game (08.0): --
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): --
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 100.00000300.00000
Foodstuffs intended for particular nutritional uses (13.0): --
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): --
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): --
Ready-to-eat savouries (15.0): 100.00000300.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): --
 
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on Flavouring Group Evaluation 40: An aromatic derivative of 2-hydroxy-propionamide. Chemical group 16
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :69297245
National Institute of Allergy and Infectious Diseases:Data
2-hydroxy-N-[2-(4-hydroxyphenyl)ethyl]propanamide
Chemidplus:0781674188
 
References:
 2-hydroxy-N-[2-(4-hydroxyphenyl)ethyl]propanamide
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):69297245
Pubchem (sid):163642632
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
ChemSpider:View
FAO:(+/-)-N-Lactoyl tyramine
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
2-hydroxy-N-(2-(4-hydroxyphenyl)ethyl)-propanamide
2-hydroxy-N-(4-hydroxyphenethyl)propanamide
2-hydroxy-N-[2-(4-hydroxyphenyl)ethyl]propanamide
(+/-)-N-lactoyl tyramine
(±)-N-lactoyl tyramine
(+/-)-N-lactoyltyramine
 propanamide, 2-hydroxy-N-(2-(4-hydroxyphenyl)ethyl)-
 
 
Notes:
None found
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