EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

alpha-eleostearic acid

Supplier Sponsors

Name:(9Z,11E,13E)-octadeca-9,11,13-trienoic acid
CAS Number: 506-23-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:208-029-2
FDA UNII: 934U1Q8QHG
XlogP3:6.40 (est)
Molecular Weight:278.43550000
Formula:C18 H30 O2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.02371 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
9(Z),11(E),13(E)-Octadecatrienoic acid ≥95%
Odor: characteristic
Use: 9(Z),11(E),13(E)-Octadecatrienoic acid (à-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. Thi
Santa Cruz Biotechnology
For experimental / research use only.
9Z,11E,13E-Octadecatrienoic Acid
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for alpha-eleostearic acid usage levels up to:
 not for fragrance use.
 
Recommendation for alpha-eleostearic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281115
National Institute of Allergy and Infectious Diseases:Data
(9Z,11E,13E)-octadeca-9,11,13-trienoic acid
Chemidplus:0000506230
 
References:
 (9Z,11E,13E)-octadeca-9,11,13-trienoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281115
Pubchem (cas):506-23-0
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
KEGG (GenomeNet):C08364
HMDB (The Human Metabolome Database):HMDB30963
FooDB:FDB012466
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 melon bitter melon cotyledon
Search Trop Picture
 melon bitter melon fruit
Search Trop Picture
 melon bitter melon seed
Search Trop Picture
 
Synonyms:
(9Z,11E,13E)-octadeca-9,11,13-trienoic acid
(9E,11Z,13E)-9,11,13-octadecatrienoic acid
(E,Z,E)-9,11,13-octadecatrienoic acid
9,11,13-octadecatrienoic acid, (9Z,11E,13E)-
 

Articles:

PubMed:Compositional Analyses and Shelf-Life Modeling of Njangsa (Ricinodendron heudelotii) Seed Oil Using the Weibull Hazard Analysis.
PubMed:α-Eleostearic acid-containing triglycerides for a continuous assay to determine lipase sn-1 and sn-3 regio-preference.
PubMed:Roles of Peroxisome Proliferator-Activated Receptor α in Bitter Melon Seed Oil-Corrected Lipid Disorders and Conversion of α-Eleostearic Acid into Rumenic Acid in C57BL/6J Mice.
PubMed:A conjugated fatty acid present at high levels in bitter melon seed favorably affects lipid metabolism in hepatocytes by increasing NAD(+)/NADH ratio and activating PPARα, AMPK and SIRT1 signaling pathway.
PubMed:A continuous spectrophotometric assay that distinguishes between phospholipase A1 and A2 activities.
PubMed:Impact of Cultivar on Profile and Concentration of Lipophilic Bioactive Compounds in Kernel Oils Recovered from Sweet Cherry (Prunus avium L.) by-Products.
PubMed:Bitter melon: a panacea for inflammation and cancer.
PubMed:New lipase assay using Pomegranate oil coating in microtiter plates.
PubMed:Silphiperfolene-Type Terpenoids and Other Metabolites from Cultures of the Tropical Ascomycete Hypoxylon rickii (Xylariaceae).
PubMed:Modulation of peroxisome proliferator-activated receptor gamma (PPAR γ) by conjugated fatty acid in obesity and inflammatory bowel disease.
PubMed:miRNA expression in human intestinal Caco-2 cells is comparably regulated by cis- and trans-fatty acids.
PubMed:Comparative real-time study of cellular uptake of a formulated conjugated linolenic acid rich nano and conventional macro emulsions and their bioactivity in ex vivo models for parenteral applications.
PubMed:Development of a high-throughput assay for measuring phospholipase A activity using synthetic 1,2-α-eleostearoyl-sn-glycero-3-phosphocholine coated on microtiter plates.
PubMed:Characterization of a soluble phosphatidic acid phosphatase in bitter melon (Momordica charantia).
PubMed:Comparative prophylactic effects of α-eleostearic acid rich nano and conventional emulsions in induced diabetic rats.
PubMed:Fatty acid profile and unigene-derived simple sequence repeat markers in tung tree (Vernicia fordii).
PubMed:Conjugated linolenic acids and their bioactivities: a review.
PubMed:Characterization of white Mahlab (Prunus mahaleb L.) seed oil: a rich source of α-eleostearic acid.
PubMed:Α-eleostearic acid inhibits growth and induces apoptosis in breast cancer cells via HER2/HER3 signaling.
PubMed:Expression analysis of VfDGAT2 in various tissues of the tung tree and in transgenic yeast.
PubMed:Effects of α-eleostearic acid on asolectin liposomes dynamics: relevance to its antioxidant activity.
PubMed:Development of a high-throughput assay for measuring lipase activity using natural triacylglycerols coated on microtiter plates.
PubMed:Jacaric acid is rapidly metabolized to conjugated linoleic acid in rats.
PubMed:Protective effect of conjugated linolenic acid isomers present in vegetable oils against arsenite-induced renal toxicity in rat model.
PubMed:Identification of a Bioactive Compound against Adult T-cell Leukaemia from Bitter Gourd Seeds.
PubMed:Synergistic effect of conjugated linolenic acid isomers against induced oxidative stress, inflammation and erythrocyte membrane disintegrity in rat model.
PubMed:Prophylactic effect of α-linolenic acid and α-eleostearic acid against MeHg induced oxidative stress, DNA damage and structural changes in RBC membrane.
PubMed:Conjugated fatty acid synthesis: residues 111 and 115 influence product partitioning of Momordica charantia conjugase.
PubMed:Studies on comparative efficacy of α-linolenic acid and α-eleostearic acid on prevention of organic mercury-induced oxidative stress in kidney and liver of rat.
PubMed:Antioxidant and anti-inflammatory effect of conjugated linolenic acid isomers against streptozotocin-induced diabetes.
PubMed:An ultraviolet spectrophotometric assay for the screening of sn-2-specific lipases using 1,3-O-dioleoyl-2-O-α-eleostearoyl-sn-glycerol as substrate.
PubMed:Dietary α-eleostearic acid ameliorates experimental inflammatory bowel disease in mice by activating peroxisome proliferator-activated receptor-γ.
PubMed:Growth inhibition and apoptotic effect of alpha-eleostearic acid on human breast cancer cells.
PubMed:Studies on the antioxygenic activity of bitter gourd (Momordica charantia) and its fractions using various in vitro models.
PubMed:Recent advances in the analysis of the site-specific isotopic fractionation of metabolites such as fatty acids using anisotropic natural-abundance 2H NMR spectroscopy: application to conjugated linolenic methyl esters.
PubMed:[Mineral elements analysis of Momordica charantiap seeds by ICP-AES and fatty acid profile identification of seed oil by GC-MS].
PubMed:Ameliorative role of conjugated linolenic acid isomers against oxidative DNA damage induced by sodium arsenite in rat model.
PubMed:Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition.
PubMed:Pomegranate (Punica granatum) seed linolenic acid isomers: concentration-dependent modulation of estrogen receptor activity.
PubMed:Alpha-eleostearic acid induces autophagy-dependent cell death through targeting AKT/mTOR and ERK1/2 signal together with the generation of reactive oxygen species.
PubMed:Alpha-eleostearic acid suppresses proliferation of MCF-7 breast cancer cells via activation of PPARgamma and inhibition of ERK 1 / 2.
PubMed:Ricinodendron heutelotii (Bail.) or Tetracarpidium conophorum Müll. oils fed to male rats lower blood lipids.
PubMed:Comparative study of antioxidant activity of alpha-eleostearic acid and punicic acid against oxidative stress generated by sodium arsenite.
PubMed:Steady-state and time-resolved fluorescence studies of stripped Borage oil.
PubMed:Alpha-eleostearic acid and its dihydroxy derivative are major apoptosis-inducing components of bitter gourd.
PubMed:Tumor angiogenesis suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via peroxisome proliferator-activated receptor gamma.
PubMed:Antioxidative effect of conjugated linolenic acid in diabetic and non-diabetic blood: an in vitro study.
PubMed:Re-characterization of three conjugated linolenic acid isomers by GC-MS and NMR.
PubMed:Characteristic long-chain fatty acid of Pleurocybella porrigens.
PubMed:Conjugated linolenic acid is slowly absorbed in rat intestine, but quickly converted to conjugated linoleic acid.
PubMed:Growth inhibition and apoptosis induction by all-trans-conjugated linolenic acids on human colon cancer cells.
PubMed:Conjugated fatty acids accumulate to high levels in phospholipids of metabolically engineered soybean and Arabidopsis seeds.
PubMed:Lipids as renewable resources: current state of chemical and biotechnological conversion and diversification.
PubMed:Lack of chemopreventive effects of alpha-eleostearic acid on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH)-induced mammary and colon carcinogenesis in female Sprague-Dawley rats.
PubMed:Inhibitory action of conjugated C18-fatty acids on DNA polymerases and DNA topoisomerases.
PubMed:Oxidation rate of conjugated linoleic acid and conjugated linolenic acid is slowed by triacylglycerol esterification and alpha-tocopherol.
PubMed:Alpha-eleostearic acid (9Z11E13E-18:3) is quickly converted to conjugated linoleic acid (9Z11E-18:2) in rats.
PubMed:Recommended methods of fatty acid methylester preparation for conjugated dienes and trienes in food and biological samples.
PubMed:Tumor growth suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation.
PubMed:Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity.
PubMed:Effect of dietary tung oil on the growth and lipid metabolism of laying hens.
PubMed:An ultraviolet spectrophotometric assay for measuring lipase activity using long-chain triacyglycerols from Aleurites fordii seeds.
PubMed:Dietary effects of conjugated octadecatrienoic fatty acid (9 cis, 11 trans, 13 trans) levels on blood lipids and nonenzymatic in vitro lipid peroxidation in rats.
PubMed:In Vivo Studies of the Biosynthesis of [alpha]-Eleostearic Acid in the Seed of Momordica charantia L.
PubMed:Isomerization of the double bonds of a conjugated fatty acid during beta-oxidation.
 
Notes:
Isol. from seed oil of Momordica charantia (bitter melon)
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy