EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

apigenin 7-O-beta-dextro-glucopyranoside

Supplier Sponsors

CAS Number: 578-74-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:209-430-5
Nikkaji Web:J407.337A
Beilstein Number:065669
XlogP3:-0.10 (est)
Molecular Weight:432.38240000
Formula:C21 H20 O10
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 788.93 °C. @ 760.00 mm Hg (est)
Flash Point: 537.00 °F. TCC ( 280.70 °C. ) (est)
logP (o/w): -0.040 (est)
Soluble in:
 water, 1417 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
Alfa Biotechnology
For experimental / research use only.
Apigetrin(Apigenin-7-O-glucoside) 98%
BOC Sciences
For experimental / research use only.
For experimental / research use only.
Apigenin-7-O-glucoside (HPLC) ≥99%
Glentham Life Sciences
Santa Cruz Biotechnology
For experimental / research use only.
Apigenin 7-glucoside ≥97%
For experimental / research use only.
Apigenin 7-glucoside
analytical standard
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
natural substances and extractives
Recommendation for cosmosiin usage levels up to:
 not for fragrance use.
Recommendation for cosmosiin flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5464455
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5464455
Pubchem (sid):135029223
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C04608
HMDB (The Human Metabolome Database):HMDB37340
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
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 apigenin 7-O-beta-dextro-glucopyranoside
 apigenin 7-O-beta-dextro-glucoside
 apigenin, 7-b-D-glycopyranoside
4H-1-benzopyran-4-one, 7-(β-D-galactopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-
7-O-.beta.-dextro-glucopyranosyl oxy-4',5-dihydroxyflavone


Google Patents:Flavor composition containing flavone glycosides
PubMed:Leaf Extract of Markhamia platycalyx: Polyphenolic Profile, Acute Toxicity, Anti-inflammatory, Hepatoprotective and in vitro Antioxidant Activities.
PubMed:Simultaneous determination of 13 chemical marker compounds in Gwakhyangjeonggi-san, a herbal formula, with validated analytical methods.
PubMed:Identification and quantification of leaf surface flavonoids in wild-growing populations of Dracocephalum kotschyi by LC-DAD-ESI-MS.
PubMed:Cytotoxic constituents from the leaves of Broussonetia papyrifera.
PubMed:Phytochemical composition and in vitro antioxidant activity of aqueous extract of Aerva lanata (L.) Juss. ex Schult. Stem (Amaranthaceae).
PubMed:Polyphenolic profile and biological activity of Salvia splendens leaves.
PubMed:[Simultaneous determination of 6 active components in Chrysanthemum morifolium by HPLC].
PubMed:Isolation of 3 flavonoids from Mentha longifolia (L.) Hudson subsp. longifolia and determination of their genotoxic potentials by using the E. coli WP2 test system.
PubMed:Flavonoid composition of Juniperus oblonga Bieb.
PubMed:Proteomic study of granulocytic differentiation induced by apigenin 7-glucoside in human promyelocytic leukemia HL-60 cells.
PubMed:Antioxidant and antigenotoxic properties of compounds isolated from Marrubium deserti de Noé.
PubMed:Generation of stable reporter breast cancer cell lines for the identification of ER subtype selective ligands.
PubMed:Phenolic chemical composition of Petroselinum crispum extract and its effect on haemostasis.
PubMed:LC determination of luteolin-7-O-β-D-glucoside and apigenin-7-O-β-D-glucoside in rat plasma after administration of Humulus scandens extract and its application to pharmacokinetic studies.
PubMed:High-performance liquid chromatographic determination and pharmacokinetic study of apigenin-7-O-β-D-glucoside in rat plasma after intravenous administration.
PubMed:Apigetrin induces erythroid differentiation of human leukemia cells K562: proteomics approach.
PubMed:Hexaconazole induces antioxidant protection and apigenin-7-glucoside accumulation in Matricaria chamomilla plants subjected to drought stress.
PubMed:A fluorescence resonance energy transfer-based fluorometer assay for screening anti-coxsackievirus B3 compounds.
PubMed:Secondary metabolites of Hypericum confertum and their possible chemotaxonomic significance.
PubMed:[Study on the flavonoids constituents of Trachelospermum jasminoides].
PubMed:Insulin-Mimetic Action of Rhoifolin and Cosmosiin Isolated from Citrus grandis (L.) Osbeck Leaves: Enhanced Adiponectin Secretion and Insulin Receptor Phosphorylation in 3T3-L1 Cells.
PubMed:Mesophyll distribution of 'antioxidant' flavonoid glycosides in Ligustrum vulgare leaves under contrasting sunlight irradiance.
PubMed:New bioactive compounds from Aloe hijazensis.
PubMed:The bioavailability of apigenin-7-glucoside is influenced by human intestinal microbiota in rats.
PubMed:[Studies on chemical constituents from Pteris multifida].
PubMed:Chemical constituents from the seeds of Trifolium alexandrinum.
PubMed:Solid-liquid transfer of biophenols from olive leaves for the enrichment of edible oils by a dynamic ultrasound-assisted approach.
PubMed:[Studies on chemical constituents in Huangjuhua (flowers of Chrysanthemum morifolium)].
PubMed:Chemical constituents from the leaves of Broussonetia papyrifera.
PubMed:Antioxidative activity of the flower of Torenia fournieri.
PubMed:[Chemical study on aerial parts of Ligusticum chuanxiong].
PubMed:Antiproliferative and apoptotic effects of chamomile extract in various human cancer cells.
PubMed:[Stduy on flavonoids in Ligustrum lucidum].
PubMed:Achillea millefolium L. s.l. -- is the anti-inflammatory activity mediated by protease inhibition?
PubMed:Phytochemical investigation and hepatoprotective activity of Cupressus sempervirens L. leaves growing in Egypt.
PubMed:[Studies on flavones in of Lavandula augustifolia].
PubMed:[Studies on chemical constituents of Acroptilon repens].
PubMed:[Determination of main flavone glycosides in Flos Chrysanthemi and observation of factors influenced contents].
PubMed:Superheated liquid extraction of oleuropein and related biophenols from olive leaves.
PubMed:Structural studies of zoospore attractants from Trachelospermum jasminoides var. pubescens: taxifolin 3-O-glycosides.
PubMed:Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism.
PubMed:Mechanisms of apigenin-7-glucoside as a hepatoprotective agent.
PubMed:Antioxidant and immunomodulatory constituents of henna leaves.
PubMed:[Studies on the flavonoids in herb from Scutellaria barbata].
PubMed:Supercritical carbon dioxide extraction of chamomile flowers: extraction efficiency, stability, and in-line inclusion of chamomile-carbon dioxide extract in beta-cyclodextrin.
PubMed:Protective effect of flavonoids against aging- and lipopolysaccharide-induced cognitive impairment in mice.
PubMed:Antioxidative glycosides from the leaves of Ligustrum robustum.
PubMed:[Studies on the chemical constituents from Chrysanthemum morifolium Ramat].
PubMed:Calmodulin inhibitors from Leucophyllum ambiguum.
PubMed:[Isolation of resisting thrombus and arteriosclerosis compounds in leaves of Salix matsudana].
PubMed:[Studies on chemical constituents of leaves of Salix matsudana Koidz and their influence on lipolysis].
PubMed:Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model.
PubMed:Effect of six flavonoid compounds from Ixeris sonchifolia on stimulus-induced superoxide generation and tyrosyl phosphorylation in human neutrophils.
PubMed:Inhibitory effect of luteolin 4'-O-glucoside from Kummerowia striata and other flavonoids on interleukin-5 bioactivity.
PubMed:Flavonoids from Aquilegia vulgaris L. Part II. Derivatives of apigenin and luteolin.
PubMed:[Separation and identification of the flavonoids from Buddleia officinalis Maxim].
PubMed:In vivo skin penetration studies of camomile flavones.
PubMed:[Absorption and excretion of apigenin, apigenin-7-glycoside and herniarin after oral administration of extracts of Matricaria recutita (L.) (syn. Chamomilla recutita (L.) Rauschert)].
PubMed:Skin anti-inflammatory activity of apigenin-7-glucoside in rats.
PubMed:[Chemical constituents of the flower of Ligustrum lucidum Ait].
PubMed:Bioflavonoid effects on in vitro cultures of Plasmodium falciparum. Inhibition of permeation pathways induced in the host cell membrane by the intraerythrocytic parasite.
PubMed:Fast atom bombardment and tandem mass spectrometry for structure determination of steroid and flavonoid glycosides.
PubMed:Transacylation in the flavonoid series. I. A new synthesis of cosmosiin and tilianin.
Constit. of flowers of Cosmos bipinnatus, Zinnia elegans, heads of Cynara scolymus, and other plant spp. [CCD] Apigetrin is a chemical compound that can be found in dandelion coffee. (Wikipedia)
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