EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

lupeol
3beta-hydroxy-20(29)-lupene

Supplier Sponsors

Name:(1R,3aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol
CAS Number: 545-47-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:208-889-9
FDA UNII: O268W13H3O
MDL:MFCD00017351
XlogP3-AA:9.90 (est)
Molecular Weight:426.72770000
Formula:C30 H50 O
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 216.00 °C. @ 760.00 mm Hg
Boiling Point: 488.11 °C. @ 760.00 mm Hg (est)
Flash Point: 422.00 °F. TCC ( 216.90 °C. ) (est)
logP (o/w): 10.460 (est)
Soluble in:
 water, 8.783e-005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Lupeol 98%
BOC Sciences
For experimental / research use only.
Lupeol 0.99
Odor: characteristic
Use: Lupeol isolated from the flower of Chrysanthemum morifolium. It enhances the radiosensitivity of SMMC-7721 cells in vitro and in vivo. antineoplastic; anti-inflammatory;
ExtraSynthese
For experimental / research use only.
Lupeol (HPLC) ≥99%
Glentham Life Sciences
Lupeol
Santa Cruz Biotechnology
For experimental / research use only.
Lupeol ≥98%
Sigma-Aldrich: Aldrich
For experimental / research use only.
Lupeol ≥94%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 > 2000 mg/kg
Fitoterapia. Vol. 68, Pg. 9, 1997.

oral-rat LD50 > 2000 mg/kg
Fitoterapia. Vol. 68, Pg. 9, 1997.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for lupeol usage levels up to:
 not for fragrance use.
 
Recommendation for lupeol flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :73040
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
(1R,3aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol
Chemidplus:0000545471
RTECS:OK5763000 for cas# 545-47-1
 
References:
 (1R,3aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):73040
Pubchem (sid):135029812
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C08628
HMDB (The Human Metabolome Database):Search
FooDB:FDB013641
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 burdock leaf
Search Trop Picture
 burdock plant
Search Trop Picture
 cantaloupe seed
Search Trop Picture
 carrot root
Search Trop Picture
 chicory
Search Trop Picture
 cucumber seed
Search Trop Picture
 date palm stem
Search Trop Picture
 elder black elder flower
Search Trop Picture
 evening-primrose fruit
Search Trop Picture
 evening-primrose inflorescence
Search Trop Picture
 fig leaf
Search Trop Picture
 grape leaf
Search Trop Picture
 grape root
Search Trop Picture
 grape stem
Search Trop Picture
 guava fruit
Search Trop Picture
 lupine white lupine seed
Search Trop Picture
 pea pigeon pea root
Search Trop Picture
 pea sprout
Search Trop Picture
 pepper bell pepper seed
Search Trop Picture
 persimmon
Search Trop Picture
 persimmon american persimmon
Search Trop Picture
 rosemary shoot
Search Trop Picture
 sage
Search Trop Picture
 salvia aegyptiaca
Search Trop Picture
 shea tree plant
Search Trop Picture
 shea tree seed oil
Search Trop Picture
 soybean seed
Search Trop Picture
 sunflower shoot
Search Trop Picture
 tea seed oil
Search Trop Picture
 tomato plant
Search Trop Picture
 verbena
Search Trop Picture
 verbena plant
Search Trop Picture
 
Synonyms:
 clerodol
 fagarasterol
 fagarsterol
(1R,3aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol
3beta-hydroxy-20(29)-lupene
 lup-20(29)-en-3-beta-ol
(3beta)-lup-20(29)-en-3-ol
 monogynol B
 triterpene lupeol
 

Articles:

PubMed:[Chemical constituents of Osmanthus fragrans fruits].
PubMed:New role of lupeol in reticence of angiogenesis, the cellular parameter of neoplastic progression in tumorigenesis models through altered gene expression.
PubMed:Cloning and Functional Characterization of Three Branch Point Oxidosqualene Cyclases From Withania somnifera (L.) Dunal.
PubMed:The effect of drought stress on the expression of key genes involved in the biosynthesis of triterpenoid saponins in liquorice (Glycyrrhiza glabra).
PubMed:Evaluation of extraction methods for preparative scale obtention of mangiferin and lupeol from mango peels (Mangifera indica L.).
PubMed:Dillenia species: A review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies.
PubMed:Antiprotozoal activities of Millettia richardiana (Fabaceae) from Madagascar.
PubMed:Anti-nociceptive, anti-inflammatory and sedative activities of the extracts and chemical constituents of Diospyros lotus L.
PubMed:A study on isolation of chemical constituents from Sophora flavescens Ait. and their anti-glioma effects.
PubMed:Systemic and local injections of lupeol inhibit tumor growth in a melanoma-bearing mouse model.
PubMed:[Study on the chemical constituents of Viscum ovalifolium].
PubMed:Isotopologue Profiling of Triterpene Formation under Physiological Conditions. Biosynthesis of Lupeol-3-(3'-R-hydroxy)-stearate in Pentalinon andrieuxii.
PubMed:A review on phytochemical, pharmacological, and pharmacognostical profile of Wrightia tinctoria: Adulterant of kurchi.
PubMed:A new sesquiterpenoid from Scaphium macropodum (Miq.) Beumee.
PubMed:[Triterpene compounds of Ainsliaea yunnanensis].
PubMed:[In vitro effect of lupeol and casearin G on peripheral blood mononuclear and tumor cells].
PubMed:Inhibition of cholinesterase activity by extracts, fractions and compounds from Calceolaria talcana and C. integrifolia (Calceolariaceae: Scrophulariaceae).
PubMed:Ethnopharmacology, phytochemistry and pharmacology of Tephrosia purpurea.
PubMed:Anti-proliferative and apoptotic activities of constituents of chloroform extract of Juglans regia leaves.
PubMed:From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract.
PubMed:Antifungal and antimycotoxigenic metabolites in Anacardiaceae species from northwest Argentina: isolation, identification and potential for control of Fusarium species.
PubMed:Inhibition of cholinesterase activity by extracts, fractions and compounds from Calceolaria talcana and C. integrifolia (Calceolariaceae: Scrophulariaceae).
PubMed:Triterpenes from Euphorbia hirta and their cytotoxicity.
PubMed:Two new flavanonols from the bark of Akschindlium godefroyanum.
PubMed:Lupeol is one of active components in the extract of Chrysanthemum indicum Linne that inhibits LMP1-induced NF-κB activation.
PubMed:New anti-inflammatory triterpene from the root of Ricinus communis.
PubMed:Analysis of constituents of the eastern Nigeria mistletoe, Loranthus micranthus linn revealed presence of new classes of osteogenic compounds.
PubMed:PI3-kinase inhibition synergistically promoted the anti-tumor effect of lupeol in hepatocellular carcinoma.
PubMed:Pharmacognostic and phytochemical studies on Ficus Microcarpa L. fil.
PubMed:Possible modulation of FAS and PTP-1B signaling in ameliorative potential of Bombax ceiba against high fat diet induced obesity.
PubMed:Anti-inflammatory effects in muscle injury by transdermal application of gel with Lychnophora pinaster aerial parts using phonophoresis in rats.
PubMed:Pyranocoumarin and triterpene from Millettia richardiana.
PubMed:[Chemical constituents in whole herb of Bidens pilosa var. radiata].
PubMed:Evaluation of Antimicrobial Activity of Bauhinia purpurea Leaves Under In Vitro Conditions.
PubMed:Phytochemical and biological studies of Solanum schimperianum Hochst.
PubMed:Antidyslipidemic and antioxidant effects of novel Lupeol-derived chalcones.
PubMed:In vitro antiprotozoal activity of triterpenoid constituents of Kleinia odora growing in Saudi Arabia.
PubMed:Non-toxic melanin production inhibitors from Garcinia livingstonei (Clusiaceae).
PubMed:Quantitative analysis of phytosterols in edible oils using APCI liquid chromatography-tandem mass spectrometry.
PubMed:A new cycloartane nortriterpenoid from stem and leaf of Quercus variabilis.
PubMed:The stem bark extracts of Cenostigma macrophyllum attenuates tactile allodynia in streptozotocin-induced diabetic rats.
PubMed:The dietary terpene lupeol targets colorectal cancer cells with constitutively active Wnt/β-catenin signaling.
PubMed:New triterpenoid acyl derivatives and biological study of Manilkara zapota (L.) Van Royen fruits.
PubMed:Anti-inflammatory effects of 27 selected terpenoid compounds tested through modulating Th1/Th2 cytokine secretion profiles using murine primary splenocytes.
PubMed:Two New 3,4;9,10-seco-Cycloartane Type Triterpenoids from Illicium difengpi and Their Anti-Inflammatory Activities.
PubMed:Synthesis and in vitro antitumor activities of lupeol dicarboxylic acid monoester derivatives.
PubMed:Glycosylsphingolipids from Euonymus japonicus Thunb.
PubMed:[Chemical constitunents of seeds of Oroxylum indicum].
PubMed:Pentacyclic triterpenes from Manilkara bidentata resin. Isolation, identification and biological properties.
PubMed:The enhanced effect of lupeol on the destruction of gastric cancer cells by NK cells.
PubMed:[Study on the chemical constituents from the leaf of Hydnocarpus hainanensis].
PubMed:Caffeoyl triterpenes from pear (Pyrus pyrifolia Nakai) fruit peels and their antioxidative activities against oxidation of rat blood plasma.
PubMed:Tyrosinase inhibitors from Calceolaria integrifolia s.l.: Calceolaria talcana aerial parts.
PubMed:Composition of Cassia fistula oil and its antifungal activity by disrupting ergosterol biosynthesis.
PubMed:Antibacterial substances from Albizia myriophylla wood against cariogenic Streptococcus mutans.
PubMed:Synthesis of novel triterpene and N-allylated/N-alkylated niacin hybrids as α-glucosidase inhibitors.
PubMed:A new pentacyclic phenol and other constituents from the root bark of Bauhinia racemosa Lamk.
PubMed:Flavonoids and triterpenes from the leaves of Artocarpus fulvicortex.
PubMed:[Study on the chemical constituents of Chloranthus multistachys].
PubMed:[Study on triterpenoids from Wisteria sinensis].
PubMed:Modulating effect of lupeol on the expression pattern of apoptotic markers in 7, 12-dimethylbenz(a)anthracene induced oral carcinogenesis.
PubMed:[Alpha-glucosidase inhibitory activity of Aeschynanthus maculatus].
PubMed:Balanophora spicata and Lupeol Acetate Possess Antinociceptive and Anti-Inflammatory Activities In Vivo and In Vitro.
PubMed:The pentacyclic triterpenoids in herbal medicines and their pharmacological activities in diabetes and diabetic complications.
PubMed:Antinociceptive effect of lupeol: evidence for a role of cytokines inhibition.
PubMed:Triterpenoid content of berries and leaves of bilberry Vaccinium myrtillus from Finland and Poland.
PubMed:Flavonoids bearing an O-arabinofuranosyl-(1-->3)-rhamnoside moiety from Cladocolea micrantha: inhibitory effect on human melanoma cells.
PubMed:Triterpenoid profile of flower and leaf cuticular waxes of heather Calluna vulgaris.
PubMed:Molecular docking analyses of Avicennia marinaderived phytochemicals against white spot syndrome virus (WSSV) envelope protein-VP28.
PubMed:Fast separation of triterpenoids by supercritical fluid chromatography/evaporative light scattering detector.
PubMed:Chemical constituents of Machaerium hirtum Vell. (Fabaceae) leaves and branches and its anti-inflammatory activity evaluation.
PubMed:Antiophidic activity of the extract of the Amazon plant Humirianthera ampla and constituents.
PubMed:Cytotoxic constituents from the stem bark of Diospyros cuneata Standl.
PubMed:Two new triterpenes from Alstonia scholaris flowers.
PubMed:Design of experiment approach for the process optimisation of microwave assisted extraction of lupeol from Ficus racemosa leaves using response surface methodology.
PubMed:Analgesic and Anti-Inflammatory Activities of Methanol Extract of Cissus repens in Mice.
PubMed:New flavane gallates isolated from the leaves of Plicosepalus curviflorus and their hypoglycemic activity.
PubMed:Constituents of twig bark of pear cultivars (Pyrus species).
PubMed:Lignans and triterpenes from the root of Pseuderanthemum carruthersii var. atropurpureum.
PubMed:One new pyrroline compound from Callistemon viminalis (Sol. Ex Gaertner) G.Don Ex Loudon.
PubMed:Naturally occurring and synthetic agents as potential anti-inflammatory and immunomodulants.
PubMed:Salt-dependent increase in triterpenoids is reversible upon transfer to fresh water in mangrove plants Kandelia candel and Bruguiera gymnorrhiza.
PubMed:A Review of the Ethnobotany and Pharmacological Importance of Alstonia boonei De Wild (Apocynaceae).
PubMed:Ring A-seco limonoids and flavonoids from the Kenyan Vepris uguenensis Engl. and their antioxidant activity.
PubMed:Composition and physiological function of the wax layers coating Arabidopsis leaves: β-amyrin negatively affects the intracuticular water barrier.
PubMed:Molecular characterization of the pentacyclic triterpenoid biosynthetic pathway in Catharanthus roseus.
PubMed:Isolation and characterization of new ceramides from aerial parts of Lepidaploa cotoneaster.
PubMed:Choisyaternatine, a new alkaloid isolated from Choisya ternata.
PubMed:Antioxidant and antimicrobial activities of ethyl acetate extract, fractions and compounds from stem bark of Albizia adianthifolia (Mimosoideae).
PubMed:Evaluation and differentiation of the Betulaceae birch bark species and their bioactive triterpene content using analytical FT-vibrational spectroscopy and GC-MS.
PubMed:Lupeol, a bioactive triterpene, prevents tumor formation during 7,12-dimethylbenz(a)anthracene induced oral carcinogenesis.
PubMed:[Triterpene compounds from Cirsium setosum].
PubMed:Novel fragmentation pathways of anionic adducts of steroids formed by electrospray anion attachment involving regioselective attachment, regiospecific decompositions, charge-induced pathways, and ion-dipole complex intermediates.
PubMed:Pharmacological basis for use of Lychnophora trichocarpha in gouty arthritis: anti-hyperuricemic and anti-inflammatory effects of its extract, fraction and constituents.
PubMed:MT1-MMP expression level status dictates the in vitro action of lupeol on inflammatory biomarkers MMP-9 and COX-2 in medulloblastoma cells.
PubMed:Investigation of the interactions of lupane type pentacyclic triterpenes with outer leaflet membrane phospholipids--Langmuir monolayer and synchrotron X-ray scattering study.
PubMed:Chemical constituents of Rhododendron lepidotum.
PubMed:QSAR, docking and in vivo studies for immunomodulatory activity of isolated triterpenoids from Eucalyptus tereticornis and Gentiana kurroo.
PubMed:Anti-inflammatory and antioxidant activities of constituents isolated from Pueraria lobata roots.
PubMed:Gastroprotective activity of Sterculia striata A. St. Hil. & Naudin (Malvaceae) in rodents.
PubMed:Rhinacanthus nasutus Extracts Prevent Glutamate and Amyloid-β Neurotoxicity in HT-22 Mouse Hippocampal Cells: Possible Active Compounds Include Lupeol, Stigmasterol and β-Sitosterol.
PubMed:Chemical and biological study of Manilkara zapota (L.) Van Royen leaves (Sapotaceae) cultivated in Egypt.
PubMed:A new triterpenoid from the rhizomes of Nelumbo nucifera.
PubMed:Comparison of the triterpenoid content of berries and leaves of lingonberry Vaccinium vitis-idaea from Finland and Poland.
PubMed:New triterpenoids from Morus alba L. stem bark.
PubMed:Chemical constituents of two sages with free radical scavenging activity.
PubMed:Synthesis and anti-HIV activity of lupane and olean-18-ene derivatives. Absolute configuration of 19,20-epoxylupanes by VCD.
PubMed:Inhibitory activities of compounds from the twigs of Garcinia hombroniana Pierre on human low-density lipoprotein (LDL) oxidation and platelet aggregation.
PubMed:Grewialin and optivanin new constituents from the stem bark of Grewia optiva Drummond ex Burret (Tiliaceae).
PubMed:Lupeol protects against acetaminophen-induced oxidative stress and cell death in rat primary hepatocytes.
PubMed:Bioactive phenolic amides from Celtis africana.
PubMed:[Study on the triterpenoids from the fruits of Ligustrum lucidum].
PubMed:Chemical constituents of the hemiparasitic plant Phoradendron brachystachyum DC Nutt (Viscaceae).
PubMed:Lupane-type pentacyclic triterpenes in Langmuir monolayers: a synchrotron radiation scattering study.
PubMed:Lupeol prevents acetaminophen-induced in vivo hepatotoxicity by altering the Bax/Bcl-2 and oxidative stress-mediated mitochondrial signaling cascade.
PubMed:A phytochemical investigation of Zanthoxylum setulosum.
PubMed:Hypoglycemic and β-cells regenerative effects of Aegle marmelos (L.) Corr. bark extract in streptozotocin-induced diabetic rats.
PubMed:Effect of Costus igneus stem extract on calcium oxalate urolithiasis in albino rats.
PubMed:Aerva lanata: A review on phytochemistry and pharmacological aspects.
PubMed:Metabolism of terpenes in the response of grape (Vitis vinifera L.) leaf tissues to UV-B radiation.
PubMed:Bioactive constituents from Harpephyllum caffrum Bernh. and Rhus coriaria L.
PubMed:Lupeol supplementation improves blood pressure and lipid metabolism parameters in stroke-prone spontaneously hypertensive rats.
PubMed:Ixora coccinea Linn.: traditional uses, phytochemistry and pharmacology.
PubMed:Antidiabetic activity of Terminalia sericea constituents.
PubMed:Simultaneous quantification of five marker compounds of Betula utilis stem bark using a validated high-performance thin-layer chromatography method.
PubMed:Pharmacological properties and related constituents of stem bark of Pterocarpus erinaceus Poir. (Fabaceae).
PubMed:Antifungal metabolites from the roots of Diospyros virginiana by overpressure layer chromatography.
PubMed:Chemical constituents and allelopathic and antioxidant activities of Alchorneopsis floribunda Müll. Arg. (Euphorbiaceae).
PubMed:Secondary metabolites from Spirotropis longifolia (DC) Baill and their antifungal activity against human pathogenic fungi.
PubMed:The triterpenes 3β-lup-20(29)-en-3-ol and 3β-lup-20(29)-en-3-yl acetate and the carbohydrate 1,2,3,4,5,6-hexa-O-acetyl-dulcitol as photosynthesis light reactions inhibitors.
PubMed:Effects of Medicinal herb Extracts and their Components on Steatogenic Hepatotoxicity in Sk-hep1 Cells.
PubMed:A new fatty aldol ester from the aerial part of Mimosa invisa (Mimosaceae).
PubMed:Evaluation of antidiabetic and antioxidant potential of lupeol in experimental hyperglycaemia.
PubMed:CYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis.
PubMed:Cembranolides from the leaves of Croton gratissimus.
PubMed:Two new xanthones from Calophyllum nodusum (Guttiferae).
PubMed:Three hydroxylated lupeol-based triterpenoid esters isolated from the Eastern Nigeria mistletoe parasitic on Kola acuminata.
PubMed:New icetexane diterpenes with intestinal α-glucosidase inhibitory and free-radical scavenging activity isolated from Premna tomentosa roots.
PubMed:Lupeol, a triterpenoid isolated from Calotropis gigantea latex ameliorates the primary and secondary complications of FCA induced adjuvant disease in experimental rats.
PubMed:Long-chain alkanoic acid esters of lupeol from Dorstenia harmsiana Engl. (Moraceae).
PubMed:[Dietetic factors associated with prostate cancer: protective effects of Mediterranean diet].
PubMed:Autophagy is induced by 3β-O-succinyl-lupeol (LD9-4) in A549 cells via up-regulation of Beclin 1 and down-regulation mTOR pathway.
PubMed:Chemical constituents of Cichorium intybus and their inhibitory effects against urease and alpha-chymotrypsin enzymes.
PubMed:Wound healing efficacy of Jatyadi Taila: in vivo evaluation in rat using excision wound model.
PubMed:Hepatoprotective constituents of Torilis radiata Moench (Apiaceae).
PubMed:Isolation and chromatographic analysis of bioactive triterpenoids from the bark extract of Cariniana domestica (Mart) Miers.
PubMed:[Studies on the chemical constituents of Coleus forskohlii transplanted in Tongcheng and their antitumor activity].
PubMed:Immunomodulatory activity of a lupane triterpenoid ester isolated from the eastern Nigeria mistletoe, Loranthus micranthus (Linn).
PubMed:Triacylglycerol and triterpene ester composition of shea nuts from seven African countries.
PubMed:[Chemical constituents from petroleum ether portion of Abelmoschus esculentus II].
PubMed:Prospective randomized clinical trial comparing phytotherapy with potassium citrate in management of minimal burden (≤8 mm) nephrolithiasis.
PubMed:Minor pregnanes from Caralluma adscendens var. gracilis and Caralluma pauciflora.
PubMed:Isolation of biologically active constituents from Moringa peregrina (Forssk.) Fiori. (family: Moringaceae) growing in Egypt.
PubMed:Lupeol, a novel androgen receptor inhibitor: implications in prostate cancer therapy.
PubMed:Asymmetric somatic hybridization between Bupleurum scorzonerifolium Willd. and Taxus chinensis var. mairei.
PubMed:Chemical constituents and in vitro antioxidant activity of Phyllanthus wightianus.
PubMed:Triterpenes involved in the anti-inflammatory effect of ethanolic extract of Pterodon emarginatus Vogel stem bark.
PubMed:Abronione, a rotenoid from the desert annual Abronia villosa.
PubMed:Brazilian red propolis: unreported substances, antioxidant and antimicrobial activities.
PubMed:Chemical constituents of Piptadenia gonoacantha J.F. Macbr.
PubMed:Mycobacterium tuberculosis and cholinesterase inhibitors from Voacanga globosa.
PubMed:Isolation and identification of acaricidal compounds in Inula japonica (Asteraceae).
PubMed:Chemical constituents of Melicope ptelefolia.
PubMed:Analgesic and anti-inflammatory property of the methanol extract from Ligustrum morrisonense leaves in rodents.
PubMed:Growth inhibition and apoptosis induced by lupeol, a dietary triterpene, in human hepatocellular carcinoma cells.
PubMed:Phytochemical evaluation and antispermatogenic activity of Thevetia peruviana methanol extract in male albino rats.
PubMed:Tyrosinase inhibitory potential of natural products isolated from various medicinal plants.
PubMed:Phytotoxic, antifungal activities and acute toxicity studies of the crude extract and compounds from Diospyros canaliculata.
PubMed:Isolation and high-performance thin layer chromatographic estimation of Lupeol from Oxystelma esculentum.
PubMed:Antiproliferative activity of Luehea candicans Mart. et Zucc. (Tiliaceae).
PubMed:Structure elucidation and NMR assignments of two new triterpenoids from the stems of Paragonia pyramidata (Bignoniaceae).
PubMed:[Chemical constituents of caulis Marsdeniae tenocissimae].
PubMed:[Chemical constituents from roots of Pueraria lobata].
PubMed:A New Ceramide Isolated from Ficus lutea Vahl (Moraceae).
PubMed:The Antimicrobial Activities of Extract and Compounds Isolated from Brillantaisia lamium.
PubMed:Compounds with tyrosinase inhibition, elastase inhibition and DPPH radical scavenging activities from the branches of Distylium racemosum Sieb. et Zucc.
PubMed:Lignans and other constituents from the roots of the Vietnamese medicinal plant Pseuderanthemum palatiferum.
PubMed:Phenylpropanoids from the stem bark of Jacaranda mimosaefolia.
PubMed:Triterpenoids from Psidium guajava with Biocidal Activity.
PubMed:Triterpenoid contents and anti-inflammatory properties of the methanol extracts of ligustrum species leaves.
PubMed:Friedolanostane, friedocycloartane and benzophenone constituents of the bark and leaves of Garcinia benthami.
PubMed:Anti-inflammatory effects and possible mechanism of action of lupeol acetate isolated from Himatanthus drasticus (Mart.) Plumel.
PubMed:Ceramide and Cerebroside from the stem bark of Ficus mucuso (Moraceae).
PubMed:[Identification of chemical compositions in ether extracts of Ligustrum lucidum by GC-MS and chemometrics].
PubMed:Chemical and biological investigations of Delonix regia (Bojer ex Hook.) Raf.
PubMed:Beneficial health effects of lupeol triterpene: a review of preclinical studies.
PubMed:Hypoglycemic evaluation of a new triterpene and other compounds isolated from Euclea undulata Thunb. var. myrtina (Ebenaceae) root bark.
PubMed:Chemical constituents of the bark of Dipteryx alata vogel, an active species against Bothrops jararacussu venom.
PubMed:[Studies on the chemical constituents of Ficus microcarpa].
PubMed:Re: Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeol.
PubMed:Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation.
PubMed:Antiplasmodial constituents from the fruit pericarp of Pentadesma butyracea.
PubMed:Further Insight into the Latex Metabolite Profile of Ficus carica.
PubMed:Screening of filamentous fungi to identify biocatalysts for lupeol biotransformation.
PubMed:[Studies on the triterpenoids constituents from Phyllodium elegans].
PubMed:Role of lupeol synthase in Lotus japonicus nodule formation.
PubMed:[Chemical constituents of stem barks of Mucuna birdwoodiana].
PubMed:Phenolic compounds in leaves of Alchornea triplinervia: anatomical localization, mutagenicity, and antibacterial activity.
PubMed:Chemical and biological investigation of some Clerodendrum species cultivated in Egypt.
PubMed:Antimicrobial and antioxidant effects of phenolic constituents from Klainedoxa gabonensis.
PubMed:Key enzymes of triterpenoid saponin biosynthesis and the induction of their activities and gene expressions in plants.
PubMed:Xanthones, biflavanones and triterpenes from Pentadesma grandifolia (Clusiaceae): structural determination and bioactivity.
PubMed:Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeol.
PubMed:Alstonia scholaris Linn R Br in the treatment and prevention of cancer: past, present, and future.
PubMed:[Studies on the chemical constituents of Ligularia macrophylla].
PubMed:Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids.
PubMed:[Chemical constituents from fruits of Ligustrum lucidum].
PubMed:Natural products from Scorzonera aristata (Asteraceae).
PubMed:Triterpene alcohol and fatty acid composition of shea nuts from seven African countries.
PubMed:Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat.
PubMed:Anti inflammatory potential of Decalepis hamiltonii (Wight and Arn) as evidenced by down regulation of pro inflammatory cytokines-TNF-alpha and IL-2.
PubMed:A pentacyclic triterpene from Litchi chinensis.
PubMed:A phenethyl bromo ester from Citharexylum fruticosum.
PubMed:Triterpenoids from aerial parts of Glochidion eriocarpum.
PubMed:An anti-influenza component of the bark of Alnus japonica.
PubMed:Chemical constituents of Periploca forrestii and their cytotoxicity activity.
PubMed:Erythropoietic activity of Asteracantha longifolia (Nees.) in rats.
PubMed:Secondary plant substances in various extracts of the leaves, fruits, stem and bark of Caraipa densifolia Mart.
PubMed:Antinociceptive effect of Zanthoxylum rhoifolium Lam. (Rutaceae) in models of acute pain in rodents.
PubMed:[Bioactive constituents from whole herbs of Vernonia cinerea (II)].
PubMed:Flavonoids with prolyl oligopeptidase inhibitory activity isolated from Scutellaria racemosa Pers.
PubMed:Anti-inflammatory effect of Acacia visco extracts in animal models.
PubMed:Triterpenoids from the stem bark of Rhizophora mucronata.
PubMed:Chemical composition of French mimosa absolute oil.
PubMed:[A novel azo-type compound from Dendrolobium triangulare].
PubMed:[A new trincallane derivative from Salacia hainanensis Chun et How].
PubMed:Diuretic and natriuretic activity of two mistletoe species in rats.
PubMed:A bioactive isoprenylated xanthone and other constituents of Garcinia edulis.
PubMed:[Chemical constituents from fruits of Ailanthus altissima].
PubMed:Boswellia frereana (frankincense) suppresses cytokine-induced matrix metalloproteinase expression and production of pro-inflammatory molecules in articular cartilage.
PubMed:Minor secondary metabolic products from the stem bark of Plumeria rubra Linn. displaying antimicrobial activities.
PubMed:Antimicrobial and cytotoxic constituents from leaves of Sapium baccatum.
PubMed:Apoptosis by dietary agents for prevention and treatment of prostate cancer.
PubMed:Triterpenoids with acetylcholinesterase inhibition from Chuquiraga erinacea D. Don. subsp. erinacea (Asteraceae).
PubMed:[Constituents of Millettia nitida var. hirsutissima].
PubMed:[Study on the constituents of petroleum ether fraction of Buxus microphylla].
PubMed:Hydrophobic metabolites from Rhododendron formosanum and their allelopathic activities.
PubMed:Analgesic and anti-inflammatory effects of Cassia siamea Lam. stem bark extracts.
PubMed:A short enantioselective total synthesis of the fundamental pentacyclic triterpene lupeol.
PubMed:Review of the use of phytosterols as a detection tool for adulteration of olive oil with hazelnut oil.
PubMed:Triterpenoids as new promising anticancer drugs.
PubMed:Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy.
PubMed:Bioactivity-guided isolation of cytotoxic constituents from stem-bark of Premna tomentosa.
PubMed:Separation and identification of some common isomeric plant triterpenoids by thin-layer chromatography and high-performance liquid chromatography.
PubMed:Turrealabdane, turreanone and an antisalmonellal agent from Turraeanthus africanus.
PubMed:Lupeol triterpene, a novel diet-based microtubule targeting agent: disrupts survivin/cFLIP activation in prostate cancer cells.
PubMed:[Studies on chemical constituents of Ligularia altaica].
PubMed:Induction of apoptosis by lupeol in human epidermoid carcinoma A431 cells through regulation of mitochondrial, Akt/PKB and NFkappaB signaling pathways.
PubMed:Gastroprotective effect of lupeol on ethanol-induced gastric damage and the underlying mechanism.
PubMed:Inhibition of protein tyrosine phosphatase 1B by lupeol and lupenone isolated from Sorbus commixta.
PubMed:Downregulation of pro-inflammatory cytokines by lupeol measured using cytometric bead array immunoassay.
PubMed:Expression of terpenoid synthase mRNA and terpenoid content in salt stressed mangrove.
PubMed:[Studies on chemical constituents in stems of Zanthoxylum dissitum].
PubMed:New bioactive compounds from Aloe hijazensis.
PubMed:Synthesis of novel triterpenoid (lupeol) derivatives and their in vivo antihyperglycemic and antidyslipidemic activity.
PubMed:[Studies on the chemical constituents from Cissus assamica].
PubMed:Mutiniside, new antioxidant phenolic glucoside from Abutilon muticum.
PubMed:Antiplasmodial activities of furoquinoline alkaloids from Teclea afzelii.
PubMed:Curtisia dentata (Cornaceae) leaf extracts and isolated compounds inhibit motility of parasitic and free-living nematodes.
PubMed:Lupeol, a novel anti-inflammatory and anti-cancer dietary triterpene.
PubMed:The regulation of inflammatory cytokine secretion in macrophage cell line by the chemical constituents of Rhus sylvestris.
PubMed:Structural determination of quercusides A and B, new flavonoid glucosides from Quercus incana, by 1D and 2D NMR spectroscopy.
PubMed:Conferols A and B, new anti-inflammatory 4-hydroxyisoflavones from Caragana conferta.
PubMed:Cytotoxic and antiplasmodial xanthones from Pentadesma butyracea.
PubMed:Biological activity of secondary metabolites from Peltostigma guatemalense.
PubMed:Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products.
PubMed:Identification and isolation of pharmacologically active triterpenes in Betuale cortex, Betula pendula Roth., Betulaceae.
PubMed:Lupeol.
PubMed:[Triterpenoids and steroids of root of Rubus biflorus].
PubMed:Lupeol, a dietary triterpene, inhibited growth, and induced apoptosis through down-regulation of DR3 in SMMC7721 cells.
PubMed:Lupeol inhibits proliferation of human prostate cancer cells by targeting beta-catenin signaling.
PubMed:Lupeol induces p53 and cyclin-B-mediated G2/M arrest and targets apoptosis through activation of caspase in mouse skin.
PubMed:Melanoma cell differentiation induced by lupeol separates into two stages: morphological and functional changes.
PubMed:[Studies on chemical constituents of Salacia prinoides].
PubMed:[Chemical constituents of Solanum cathayanum].
PubMed:Suppression of cFLIP by lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells.
PubMed:Dual biosynthetic pathways to phytosterol via cycloartenol and lanosterol in Arabidopsis.
PubMed:Anti-oxidative and anti-inflammatory activities of some isolated constituents from the stem bark of Allanblackia monticola Staner L.C (Guttiferae).
PubMed:[Research on chemical constituents from stem of Gymnema sylvestre].
PubMed:Byrsonima fagifolia Niedenzu Apolar Compounds with Antitubercular Activity.
PubMed:A new chalcone glycoside from Rhamnus nipalensis.
PubMed:Xanthones from the seeds of Allanblackia monticola and their apoptotic and antiproliferative activities.
PubMed:Portulene, a new diterpene from Portulaca oleracea L.
PubMed:Differentiation-inducing activity of lupane triterpenes on a mouse melanoma cell line.
PubMed:A new monoterpene alkaloid and other constituents of Plumeria acutifolia.
PubMed:[Study on liposoluble constituents of Teucrium labiosum].
PubMed:Validation of a method for the determination of sterols and triterpenes in the aerial part of Justicia anselliana (Nees) T. Anders by capillary gas chromatography.
PubMed:Seasonal variations in the chemical composition of vine-grape leaf surface.
PubMed:Sorocenols G and H, anti-MRSA oxygen heterocyclic Diels-Alder-type adducts from Sorocea muriculata roots.
PubMed:[Studies on chemical constituents from Euonymus alatus II].
PubMed:Active metabolites from Dunalia spinosa resinous exudates.
PubMed:Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria.
PubMed:A triterpenoidal saponin and sphingolipids from Pteleopsis hylodendron.
PubMed:Four pentacyclic triterpenoids with antifungal and antibacterial activity from Curtisia dentata (Burm.f) C.A. Sm. leaves.
PubMed:[Study on chemical constituents in roots and rhizomes of Ligularia duciforms II].
PubMed:Chemical constituents from Clerodendron serratum.
PubMed:Report: quantitative estimation of beta-sitosterol, lupeol, quercetin and quercetin glycosides from leaflets of Soymida febrifuga using HPTLC technique.
PubMed:The triterpenoid lupeol attenuates allergic airway inflammation in a murine model.
PubMed:Betulin binds to gamma-aminobutyric acid receptors and exerts anticonvulsant action in mice.
PubMed:Antibacterial activity of labdane diterpenoids from Stemodia foliosa.
PubMed:Secondary metabolites from Tectona philippinensis.
PubMed:Chemical investigation of Finlaysonia obovata: part I--a rare triterpene acid showing antibacterial activity against fish pathogens.
PubMed:A new dibenzofuran and other constituents from Ligularia caloxantha, a Chinese medicinal plant.
PubMed:Protective effect of lupeol and lupeol linoleate in hypercholesterolemia associated renal damage.
PubMed:[Study on triterpenes from of Ligularia xanthotricha].
PubMed:Identification of chemical compounds from the leaves of Leea indica.
PubMed:Protective effects of lupeol against benzo[a]pyrene induced clastogenicity in mouse bone marrow cells.
PubMed:Potential anti-tumor-promoting activity of 3alpha-hydroxy-D:A-friedooleanan-2-one from the stem bark of Mallotus philippensis.
PubMed:Induction of apoptosis by lupeol and mango extract in mouse prostate and LNCaP cells.
PubMed:Regulation of signaling pathways involved in lupeol induced inhibition of proliferation and induction of apoptosis in human prostate cancer cells.
PubMed:A new benzofuranic acid from the leaves of Rhus alata.
PubMed:Dietary agents for chemoprevention of prostate cancer.
PubMed:Lupeol inhibits growth of highly aggressive human metastatic melanoma cells in vitro and in vivo by inducing apoptosis.
PubMed:Development of liquid chromatographic methods for the determination of phytosterols in Standard Reference Materials containing saw palmetto.
PubMed:Modulatory effect of Byrsonima basiloba extracts on the mutagenicity of certain direct and indirect-acting mutagens in Salmonella typhimurium assays.
PubMed:Lupeol: connotations for chemoprevention.
PubMed:alpha-Glucosidase inhibitory activity of triterpenoids from Cichorium intybus.
PubMed:Synthesis of lupane-type saponins bearing mannosyl and 3,6-branched trimannosyl residues and their evaluation as anticancer agents.
PubMed:Novel class of hybrid natural products derived from lupeol as antimalarial agents.
PubMed:[Studies on chemical constituents of Liriope platyphylla].
PubMed:Wound healing activity and docking of glycogen-synthase-kinase-3-beta-protein with isolated triterpenoid lupeol in rats.
PubMed:Tyrosinase inhibitors and sesquiterpene diglycosides from Guioa villosa.
PubMed:Antibacterial activities and cytotoxicity of terpenoids isolated from Spirostachys africana.
PubMed:Seco-terpenoids and other constituents from Elateriospermum tapos.
PubMed:Erythrina alkaloids and a pterocarpan from the bark of Erythrina subumbrans.
PubMed:Cancer chemoprevention through dietary antioxidants: progress and promise.
PubMed:NMR spectral assignments of a new [C--O--C] isoflavone dimer from Andira surinamensis.
PubMed:Protective effects of lupeol and mango extract against androgen induced oxidative stress in Swiss albino mice.
PubMed:Biological activities of the chemical constituents of Erythrina stricta and Erythrina subumbrans.
PubMed:Some natural compounds enhance N epsilon-(carboxymethyl)lysine formation.
PubMed:[Studies on triterpenoid constituents in leaf of Ilex pernyi].
PubMed:Analytical investigation of styrax and benzoin balsams by HPLC- PAD-fluorimetry and GC-MS.
PubMed:Chemical phenotypes of the hmg1 and hmg2 mutants of Arabidopsis demonstrate the in-planta role of HMG-CoA reductase in triterpene biosynthesis.
PubMed:Phytochemical and antinociceptive properties of Matayba elaeagnoides Radlk. barks.
PubMed:Lupeol suppresses cisplatin-induced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model.
PubMed:Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae.
PubMed:Anti-inflammatory and analgesic activities of the ethanolic extracts from Zanthoxylum riedelianum (Rutaceae) leaves and stem bark.
PubMed:Flavaglines and triterpenoids from the leaves of Aglaia forbesii.
PubMed:Antiplasmodial compounds from Cassia siamea stem bark extract.
PubMed:Determination of three major triterpenoids in epicuticular wax of cabbage (Brassica oleracea L.) by high-performance liquid chromatography with UV and mass spectrometric detection.
PubMed:[Study on chemical constiuents from Ligularia intermedia of shanxi].
PubMed:Lipid constituents of Trifolium resupinatum var. microcephalum.
PubMed:Preventive effects of lupeol on DMBA induced DNA alkylation damage in mouse skin.
PubMed:Anticytomegalovirus activity of pristimerin, a triterpenoid quinone methide isolated from Maytenus heterophylla (Eckl. & Zeyh.).
PubMed:A new fatty acid ester of triterpenoid from Celastrus rosthornianus with anti-tumor activitives.
PubMed:Naturally occurring compounds affect glutamatergic neurotransmission in rat brain.
PubMed:Triterpenoids from swallow roots--a convenient HPLC method for separation.
PubMed:Identification and determination of triterpenoids in Hieracium pilosella L.
PubMed:Two triterpenes lupanone and lupeol isolated and identified from Tamarindus indica linn.
PubMed:Prevention of prostate cancer through custom tailoring of chemopreventive regimen.
PubMed:Antihyperglycemic activity of Rhizophora apiculata Bl. in rats.
PubMed:A new flavonol from Sophora tonkinensis.
PubMed:[Terpenoid compounds isolated from Ligularia sagitta].
PubMed:[Chemical constitutents of Bauhinia aurea].
PubMed:Hepatoprotective effects of lupeol and mango pulp extract of carcinogen induced alteration in Swiss albino mice.
PubMed:Protective effect of lupeol and its ester on cardiac abnormalities in experimental hypercholesterolemia.
PubMed:Constituents of the leaves of Holarrhena pubescens.
PubMed:alpha-Glucosidase inhibitory pentacyclic triterpenes from the stem bark of Fagara tessmannii (Rutaceae).
PubMed:Oxyfunctionalization products of terpenoids with dimethyldioxirane and their biological activity.
PubMed:ent-Beyerane diterpenoids from the heartwood of Excoecaria parvifolia.
PubMed:Two new tetracyclic triterpenes from the heartwood of Ailanthus excelsa Roxb.
PubMed:Antihyperglycemic activity and chemical constituents of Eysenhardtia platycarpa.
PubMed:Pentacyclic triterpenes with selective bioactivity from Sebastiania adenophora leaves, Euphorbiaceae.
PubMed:Antidermatophytic triterpenoids from Syzygium jambos (L.) Alston (Myrtaceae).
PubMed:Stereochemical course in water addition during LUP1-catalyzed triterpene cyclization.
PubMed:Effect of lupeol and lupeol linoleate on lipemic--hepatocellular aberrations in rats fed a high cholesterol diet.
PubMed:Physical, chemical and pharmacological characterization of a new oleogel-forming triterpene extract from the outer bark of birch (betulae cortex).
PubMed:Molecular cloning and functional expression of a multifunctional triterpene synthase cDNA from a mangrove species Kandelia candel (L.) Druce.
PubMed:A novel isoflavonoid from Millettia puguensis.
PubMed:[Compounds from marine mangrove plant Bruguiera sexangula var. rhynchopetala].
PubMed:Lupeol and its ester inhibit alteration of myocardial permeability in cyclophosphamide administered rats.
PubMed:Mitigating role of lupeol and lupeol linoleate on hepatic lipemic-oxidative injury and lipoprotein peroxidation in experimental hypercholesterolemia.
PubMed:alpha-Glucosidase inhibitory activity of the methanolic extract from Tournefortia hartwegiana: an anti-hyperglycemic agent.
PubMed:Triterpenoids from Drypetes chevalieri Beille (euphorbiaceae).
PubMed:Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents.
PubMed:Constituents of Salvia microphylla.
PubMed:Loading of erythrocyte membrane with pentacyclic triterpenes inhibits Plasmodium falciparum invasion.
PubMed:Lupeol ameliorates aflatoxin B1-induced peroxidative hepatic damage in rats.
PubMed:alpha-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus.
PubMed:Chemical study of triterpenoid resinous materials in archaeological findings by means of direct exposure electron ionisation mass spectrometry and gas chromatography/mass spectrometry.
PubMed:Two new 18-en-oleane derivatives from marine mangrove plant, Barringtonia racemosa.
PubMed:Acyl-CoA: cholesterol acyltransferase inhibitors from Ilex macropoda.
PubMed:Ceanothane- and lupane-type triterpenes with antiplasmodial and antimycobacterial activities from Ziziphus cambodiana.
PubMed:Suppression of T lymphocyte activity by lupeol isolated from Crataeva religiosa.
PubMed:[Treatment of actinic keratoses with birch bark extract: a pilot study].
PubMed:Lupeol and its ester exhibit protective role against cyclophosphamide-induced cardiac mitochondrial toxicity.
PubMed:Mechanistic insights into triterpene synthesis from quantum mechanical calculations. Detection of systematic errors in B3LYP cyclization energies.
PubMed:Cloning and characterization of a lupeol synthase involved in the synthesis of epicuticular wax crystals on stem and hypocotyl surfaces of Ricinus communis.
PubMed:Lupeol long-chain fatty acid esters with antimalarial activity from Holarrhena floribunda.
PubMed:Daboia russellii and Naja kaouthia venom neutralization by lupeol acetate isolated from the root extract of Indian sarsaparilla Hemidesmus indicus R.Br.
PubMed:Enzymatic cyclization of dioxidosqualene to heterocyclic triterpenes.
PubMed:Structural determination of 3beta-stearyloxy-urs-12-ene from Maytenus salicifolia by 1D and 2D NMR and quantitative 13C NMR spectroscopy.
PubMed:A novel dietary triterpene Lupeol induces fas-mediated apoptotic death of androgen-sensitive prostate cancer cells and inhibits tumor growth in a xenograft model.
PubMed:Lupeol and its ester ameliorate the cyclophosphamide provoked cardiac lysosomal damage studied in rat.
PubMed:Remodeling of actin cytoskeleton in lupeol-induced B16 2F2 cell differentiation.
PubMed:Role of lupeol and its ester on cyclophosphamide-induced hyperlipidaemic cardiomyopathy in rats.
PubMed:Crystal structures of the free and sterol-bound forms of beta-cinnamomin.
PubMed:[Chemical investingation of Chinese mangrove Sonneratia apetala II].
PubMed:Role of lupeol and lupeol linoleate on lipemic-oxidative stress in experimental hypercholesterolemia.
PubMed:Surface composition of myrmecophilic plants: cuticular wax and glandular trichomes on leaves of Macaranga tanarius.
PubMed:Plant sterols and stanols: effects on mixed micellar composition and LXR (target gene) activation.
PubMed:The chemical constituents of Ligularia pleurocaulis.
PubMed:Unusual naphthoquinones, catechin and triterpene from Byrsonima microphylla.
PubMed:Expression of estrogen receptor alpha gene in breast cancer cells treated with transcription factor decoy is modulated by Bangladeshi natural plant extracts.
PubMed:Bangangxanthone A and B, two xanthones from the stem bark of Garcinia polyantha Oliv.
PubMed:Induction of antifertility with lupeol acetate in male albino rats.
PubMed:Tabouensinium chloride, a novel quaternary pyranoquinoline alkaloid from Araliopsis tabouensis.
PubMed:Cardioprotective effect of pentacyclic triterpene, lupeol and its ester on cyclophosphamide-induced oxidative stress.
PubMed:Structure and reactivity of the dammarenyl cation: configurational transmission in triterpene synthesis.
PubMed:[Studies on chemical constituents from Salvia roborowskii Maxim].
PubMed:Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway.
PubMed:Antimicrobial terpenoids from Pterocarpus indicus.
PubMed:New indolopyridoquinazoline, benzo[c]phenanthridines and cytotoxic constituents from Zanthoxylum integrifoliolum.
PubMed:Prenylated anthronoid antioxidants from the stem bark of Harungana madagascariensis.
PubMed:Caesaldecan, a cassane diterpenoid from the leaves of Caesalpinia decapetala.
PubMed:A new flavonol glycoside derivative from leaves of Moldenhawera nutans.
PubMed:Prenylated chalcones, flavone and other constituents of the twigs of Dorstenia angusticornis and Dorstenia barteri var. subtriangularis.
PubMed:Cytotoxic activity of lupane-type triterpenes from Glochidion sphaerogynum and Glochidion eriocarpum two of which induce apoptosis.
PubMed:An antibacterial biphenyl derivative from Garcinia bancana MIQ.
PubMed:A new glucoceramide from the watermelon Begonia, Pellionia repens.
PubMed:A new and known cytotoxic aryltetralin-type lignans from stems of Bursera graveolens.
PubMed:Two diterpenes and three diterpene glucosides from Phlogacanthus curviflorus.
PubMed:Potential anti-tumor promoting activity of lupane-type triterpenoids from the stem bark of Glochidion zeylanicum and Phyllanthus flexuosus.
PubMed:Apoptosis inducing activity of viscin, a lipophilic extract from Viscum album L.
PubMed:A new triterpenoid ester from the fruits of Bruguiera parviflora.
PubMed:Glycosides from Grewia damine and Filicium decipiens.
PubMed:Furanolabdane diterpenes from Hypoestes purpurea.
PubMed:Antibacterial activity of naphthoquinones and triterpenoids from Euclea natalensis root bark.
PubMed:[Studies on chemical constituents of Caesalpinia decapetala (Roth) Alston].
PubMed:[Studies on chemical constituents of Salvia roborowskii Maxim].
PubMed:New lupane triterpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase beta.
PubMed:A new sesquiterpene-coumarin ether and a new abietane diterpene and their effects as inhibitors of P-glycoprotein.
PubMed:A new lignan glycoside and phenylethanoid glycosides from Strobilanthes cusia BREMEK.
PubMed:Allanxanthone B, a polyisoprenylated xanthone from the stem bark of Allanblackia monticola Staner L.C.
PubMed:Enzymatic synthesis of an indole diterpene by an oxidosqualene cyclase: mechanistic, biosynthetic, and phylogenetic implications.
PubMed:Apoptotic activity of betulinic acid derivatives on murine melanoma B16 cell line.
PubMed:Effect of lupeol isolated from Crataeva nurvala Buch.-Ham. stem bark extract against free radical induced nephrotoxicity in rats.
PubMed:Lignans from the roots of Echinops giganteus.
PubMed:Cytotoxic constituents from Plumbago zeylanica.
PubMed:Differential expression of three oxidosqualene cyclase mRNAs in Glycyrrhiza glabra.
PubMed:Lupeol, a triterpene, prevents free radical mediated macromolecular damage and alleviates benzoyl peroxide induced biochemical alterations in murine skin.
PubMed:Anti-inflammatory constituents of Mortonia greggii Gray.
PubMed:New cycloartenol esters from Ixora coccinea.
PubMed:A new 3,4-seco-lupane derivative from Lasianthus gardneri.
PubMed:New cytotoxic terpenoids from the wood of Vepris punctata from the Madagascar Rainforest.
PubMed:Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice.
PubMed:Lipoxygenase inhibition by anadanthoflavone, a new flavonoid from the aerial parts of Anadenanthera colubrina.
PubMed:Cytotoxic lupane-type triterpenoids from Acacia mellifera.
PubMed:Cytotoxic activity of five compounds isolated from Colombian plants.
PubMed:Prolyl endopeptidase inhibitors from Syzygium samarangense (Blume) Merr. & L. M. Perry.
PubMed:[Studies on chemical constituents in leafs of Ilex kudingcha].
PubMed:[Chemical constituents from the leaves of Dalbergia hainanensis].
PubMed:Characterization of archaeological frankincense by gas chromatography-mass spectrometry.
PubMed:[A review of the study on kudingcha].
PubMed:A new pterocarpan, (-)-maackiain sulfate, from the roots of Sophora subprostrata.
PubMed:Induction of apoptosis by lupeol isolated from mokumen (Gossampinus malabarica L. Merr) in human promyelotic leukemia HL-60 cells.
PubMed:Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues.
PubMed:[Studies on the chemical constituents of Ampelopsis humulifolia var. heterophylla (Thunb.) K. Koch].
PubMed:Antimicrobial and cytotoxicity evaluation of Buchholzia coriacea stem bark.
PubMed:Triterpenoids from the stembark of Pyrus communis.
PubMed:Antiprotease effect of anti-inflammatory lupeol esters.
PubMed:Role of p38 MAPK in lupeol-induced B16 2F2 mouse melanoma cell differentiation.
PubMed:Evaluation of the analgesic activity of extracts of Miconia rubiginosa (Melastomataceae).
PubMed:Antiplasmodial triterpenes from twigs of Gardenia saxatilis.
PubMed:Immunomodulatory triterpenoids from the oleogum resin of Boswellia carterii Birdwood.
PubMed:Biflavonoids and a glucopyranoside derivative from Ouratea semiserrata.
PubMed:Antimicrobial activity of terpenoids from Trichodesma amplexicaule Roth.
PubMed:[Studies on the chemical constituents of the stems of Alyxia sinensis (I)].
PubMed:Biological activity of some naturally occurring resins, gums and pigments against in vitro LDL oxidation.
PubMed:Oxidosqualene cyclases from cell suspension cultures of Betula platyphylla var. japonica: molecular evolution of oxidosqualene cyclases in higher plants.
PubMed:Antiangiogenic activity of lupeol from Bombax ceiba.
PubMed:Chemical composition of Tipuana tipu, a source for tropical honey bee products.
PubMed:Eremophilenolides and other constituents from the roots of Ligularia sagitta.
PubMed:New cytotoxic lupane triterpenoids from the twigs of Coussarea paniculata.
PubMed:Constituents of antibacterial extract of Caesalpinia paraguariensis Burk.
PubMed:Homologous very-long-chain 1,3-alkanediols and 3-hydroxyaldehydes in leaf cuticular waxes of Ricinus communis L.
PubMed:Irritant potential of some constituents from the seeds of Caesalpinia bonducella (L.) fleming.
PubMed:Lipid composition of mangrove and its relevance to salt tolerance.
PubMed:Hypotensive activity and toxicology of constituents from Bombax ceiba stem bark.
PubMed:Constituents of Acacia cedilloi and Acacia gaumeri. Revised structure and complete NMR assignments of resinone.
PubMed:Pentacyclic triterpenoids from Ilex macropoda.
PubMed:Triterpenes and phytosterols as human leucocyte elastase inhibitors.
PubMed:Effect of three triterpenoids, lupeol, betulin, and betulinic acid on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
PubMed:Solid-phase synthesis and bioevaluation of lupeol-based libraries as antimalarial agents.
PubMed:Lupeol alkanoates in Brazilian propolis.
PubMed:Flavonoids from Tephrosia major. A new prenyl-beta-hydroxychalcone.
PubMed:Evaluation of the effect of triterpenes on urinary risk factors of stone formation in pyridoxine deficient hyperoxaluric rats.
PubMed:[A study on major chemical components of Uvaria grandiflora].
PubMed:Two new triterpene esters from the twigs of Brachylaena ramiflora from the Madagascar rainforest.
PubMed:A bis-bithiophene from Tridax procumbens L. (Asteraceae).
PubMed:Irritant potential of triterpenoids from Ficus carica leaves.
PubMed:Triterpenoids from Parthenium argentatum x P. tomentosa.
PubMed:Diterpenoids from the stem bark of Croton zambesicus.
PubMed:Differentiation- and apoptosis-inducing activities by pentacyclic triterpenes on a mouse melanoma cell line.
PubMed:Chemical composition and ultrastructure of broad bean (Vicia faba L.) nodule endodermis in comparison to the root endodermis.
PubMed:In vitro Plasmodium falciparum drug sensitivity assay: inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane.
PubMed:Triterpenoids from Gentiana scabra.
PubMed:Two novel long-chain alkanoic acid esters of lupeol from alecrim-propolis.
PubMed:Bowdenol, a new 2,3-dihydrobenzofuran constituent from Bowdichia virgilioides.
PubMed:Phytosterol content in American ginseng seed oil.
PubMed:New ursane-type triterpenic esters from the stem bark of Thevetia peruviana.
PubMed:Screening of triterpenoids isolated from Phyllanthus flexuosus for DNA topoisomerase inhibitory activity.
PubMed:Proposed active constituents of Dipladenia martiana.
PubMed:Apianane terpenoids from Salvia officinalis.
PubMed:New insights into the mechanism of action of the anti-inflammatory triterpene lupeol.
PubMed:A bioactive spirolactone iridoid and triterpenoids from Himatanthus sucuuba.
PubMed:Triterpenoids from Bersama swinnyi.
PubMed:[Chemical constituents of Quercus mongolica Fisch].
PubMed:Sterols, triterpenes and biflavonoids of Viburnum jucundum and cytotoxic activity of ursolic acid.
PubMed:Cloning and characterization of a cDNA encoding beta-amyrin synthase involved in glycyrrhizin and soyasaponin biosyntheses in licorice.
PubMed:Cytotoxic activity of moronic acid and identification of the new triterpene 3,4-seco-olean-18-ene-3,28-dioic acid from Phoradendron reichenbachianum.
PubMed:[Description, distribution, anatomy, chemical composition and uses of Mimosa tenuiflora(Fabaceae-Mimosoideae) in Mexico].
PubMed:Control of urinary risk factors of stones by betulin and lupeol in experimental hyperoxaluria.
PubMed:Lupeol esters from the twig bark of Japanese pear (Pyrus serotina Rehd.) cv. Shinko.
PubMed:Constituents of the stem bark of Ormosia wayana.
PubMed:Hepatoprotective effect of lupeol and lupeol linoleate on tissue antioxidant defence system in cadmium-induced hepatotoxicity in rats.
PubMed:Anti-inflammatory effect of Pimenta racemosa var. ozua and isolation of the triterpene lupeol.
PubMed:3,4-seco-Lupanes and other constituents from Platypodium elegans.
PubMed:Ursene type nortriterpene from Debregeasia salicifolia.
PubMed:Anti-inflammatory activity of lupeol and lupeol linoleate in rats.
PubMed:Cytotoxic principles from Ventilago leiocarpa.
PubMed:Effects of antiinflammatory triterpenes isolated from Leptadenia hastata latex on keratinocyte proliferation.
PubMed:Triterpenoids from Dysoxylum malabaricum.
PubMed:Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana.
PubMed:Lupeol, a triterpene, inhibits early responses of tumor promotion induced by benzoyl peroxide in murine skin.
PubMed:A novel derivative pentacyclic triterpene and omega 3 fatty acid.
PubMed:A new oleanane glycoside from the stem bark of Albizia gummifera.
PubMed:Release of intermediate reactive hydrogen peroxide by macrophage cells activated by natural products.
PubMed:Effect of lupeol, a pentacyclic triterpene, on the lipid peroxidation and antioxidant status in rat kidney after chronic cadmium exposure.
PubMed:Major constituents of the foliar epicuticular waxes of species from the Caatinga and Cerrado.
PubMed:A new lupane caffeoyl ester from Hippocratea volubilis.
PubMed:Effect of pentacyclic triterpenes on oxalate-induced changes in rat erythrocytes.
PubMed:Differentiation-inducing activity of lupeol, a lupane-type triterpene from Chinese dandelion root (Hokouei-kon), on a mouse melanoma cell line.
PubMed:Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol.
PubMed:Lupene-type triterpenes from Periploca aphylla.
PubMed:Anti-inflammatory and analgesic activities of the latex containing triterpenes from Himatanthus sucuuba.
PubMed:Inhibition of serine proteases by anti-inflammatory triterpenoids.
PubMed:Two glycosides from the stem bark of Tetracentron sinense.
PubMed:[Synthesis of the lupane group triterpenoids and there hepatoprotective activity].
PubMed:Chemical characterization and biological activity of Macfadyena unguis-cati (Bignoniaceae).
PubMed:Constituents of Caesalpinia pyramidalis.
PubMed:Bioactive constituents of the bark of Parkia biglobosa.
PubMed:Protective effect of triterpenes on calcium oxalate crystal-induced peroxidative changes in experimental urolithiasis.
PubMed:Unsaponifiable lipid constituents of some underutilized tropical seed oils.
PubMed:Xanthones and triterpenoids from the bark of Garcinia vilersiana.
PubMed:Pentacyclic triterpenes from Chuquiraga ulicina.
PubMed:Effect of lupeol and lupeol linoleate on lysosomal enzymes and collagen in adjuvant-induced arthritis in rats.
PubMed:Constituents of zanthoxylum sprucei.
PubMed:The traditional plant treatment, Sambucus nigra (elder), exhibits insulin-like and insulin-releasing actions in vitro.
PubMed:Two branches of the lupeol synthase gene in the molecular evolution of plant oxidosqualene cyclases.
PubMed:Molluscicidal constituents of Marsypianthes chamaedrys.
PubMed:Anticomplement activity of triterpenes from Crataeva nurvala stem bark in adjuvant arthritis in rats.
PubMed:Selective inhibition of eukaryote protein kinases by anti-inflammatory triterpenoids.
PubMed:A new amide from zanthoxylum armatum
PubMed:Terpenoids of Syzygium formosanum.
PubMed:Cloning and characterization of the Arabidopsis thaliana lupeol synthase gene.
PubMed:Beta-amyrin synthase--cloning of oxidosqualene cyclase that catalyzes the formation of the most popular triterpene among higher plants.
PubMed:Lupeol is the cytotoxic principle in the leaf extract of Dendropanax cf. querceti.
PubMed:Effect of triterpenes from Crataeva nurvala stem bark on lipid peroxidation in adjuvant induced arthritis in rats.
PubMed:Antiplasmodial triterpene from Vernonia brasiliana.
PubMed:Norditerpenoids and diterpenoids from Salvia multicaulis with antituberculous activity.
PubMed:Cytotoxic constituents from the stems of Diospyros maritima.
PubMed:Linear, steroidal, and triterpene esters, and steryl glycosides from Festuca argentina.
PubMed:Antimutagens from Plumeria acuminata Ait.
PubMed:Triterpene alcohols from the flowers of compositae and their anti-inflammatory effects.
PubMed:Constituents from the stem wood of Euphorbia quinquecostata with phorbol dibutyrate receptor-binding inhibitory activity.
PubMed:A new sesquiterpene lactone from Elephantopus mollis.
PubMed:Chemical and biological investigation of the root bark of Clerodendrum mandarinorum.
PubMed:Lupane derivatives from Lophopetalum wallichii with farnesyl protein transferase inhibitory activity.
PubMed:[Chemical constituents in roots of Ampelopsis sinica (Miq.) W.T. Wang].
PubMed:[Chemical components of Lindernia ciliata (Colsm) Pennell].
PubMed:Effect of lupeol, a pentacyclic triterpene, on urinary enzymes in hyperoxaluric rats.
PubMed:Some lupane-type triterpenes inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin.
PubMed:Aloe vera, hydrocortisone, and sterol influence on wound tensile strength and anti-inflammation.
PubMed:The role of triterpenoids in the topical anti-inflammatory activity of Calendula officinalis flowers.
PubMed:Antimicrobial activity of Visnea mocanera leaf extracts.
PubMed:A New Triterpenoidal from Vernonia cinerea.
PubMed:Pharmacognosy of Mimosa tenuiflora (Willd.) Poiret.
PubMed:[Chemical studies of Strobilanthes cusia].
PubMed:[Studies on the chemical constituents of Desmodium styracifolium (Osbeck) Merr].
PubMed:Biological and chemical studies of Pera benensis, a Bolivian plant used in folk medicine as a treatment of cutaneous leishmaniasis.
PubMed:Isolation and identification of xochitloldione and isoxochitlolone from Cnidosculus urens.
PubMed:[Studies on the chemical constituents of Cynanchum thesioides].
PubMed:Triterpene saponins from the roots of Ampelozizyphus amazonicus.
PubMed:Constituents and biological activity of Bidens pilosa L. grown in Egypt.
PubMed:[Sedative chemical constituents of leaves of Apocynum venetum Linn].
PubMed:[Studies on the chemical constituents of Flemingia philippinensis].
PubMed:[Isolation and identification of cynanester A from Cynanchum chinense R. Br].
PubMed:Leucasin, a triterpene saponin from Leucas nutans.
PubMed:Lignans and other constituents from South and central american zanthoxylum species.
PubMed:[Studies on the chemical constituents of Rhynchotechum vestitum Hook. F. et Thoms].
PubMed:Examination of triterpenoids produced by callus and cell suspension cultures of Glycyrrhiza glabra.
PubMed:[Study on anthraquinones of Uentilago leiocarpa].
PubMed:[Chemical constituents of Sophora glauca Lesch].
PubMed:[Isolation and identification of the lipophilic constituents from the root of Euphorbia fischeriana Steud].
PubMed:Constituents of the Stems of Arbutus unedo.
PubMed:Investigation of Grewia bicolor Juss.
PubMed:Limonoids of Teclea ouabanguiensis.
PubMed:A Contribution to the Phytochemistry of Zanthoxylum tessmannii1.
PubMed:3 beta-hydroxy-28-P-coumaroyloxy-lup-20(29)-en-27-oic acid from Caraipa densifolia.
PubMed:Antitumor agents XXXVIII: Isolation and structural elucidation of novel germacranolides and triterpenes from Elephantopus mollis.
PubMed:Tumor inhibitors II: constituents and antitumor activity of Sarracenia flava.
PubMed:Analysis of methylsterol fractions from twenty vegetable oils.
PubMed:Structure of lupeol and its 19alpha-H-isomer.
PubMed:Isolation of 19alpha-H-lupeol from Maclura pomifera.
PubMed:Pentacylic triterpenes ofJurinea anatolic boiss. andJurinea consanguinea DC. Fruit.
PubMed:Studies on the sterol of Bombyx mori. V. Lupeol in silkworm blood.
PubMed:ACTION OF RANEY NICKEL ON LUPEOL.
PubMed:Isolation of lupeol from Sweetia panamensis.
PubMed:[Obtention and identification of lupeol from the strawberry tree (Arbutus unedo L.)].
PubMed:A phytochemical investigation of the fruit of Maclura pomifera (Rafinesque) Schneider. III. Color tests, paper chromatography, and infrared spectra of lurenol, lupeol, and their derivatives.
 
Notes:
None found
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy